{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T18:47:45Z","timestamp":1776710865910,"version":"3.51.2"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:sec>\n                    <jats:title>OBJECTIVES:<\/jats:title>\n                    <jats:p>To determine whether 6\u201312 weeks modified Radiographic Union Score for Tibial fractures (mRUST) scores after lateral locked plating (LLP) of distal femur fractures were associated with nonunion versus healing.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>Retrospective case\u2013control study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting:<\/jats:title>\n                    <jats:p>Two Level 1 Trauma Centers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patient Selection Criteria:<\/jats:title>\n                    <jats:p>Included were adult patients with distal femur fractures (OTA\/AO 33A\/C) treated with LLP between 2006 and 2024 and with available postoperative radiographs between 6 and 12 weeks. Nonunion cases were defined as patients undergoing reoperation for nonunion after 12 weeks and were randomly matched 1:2 to controls, defined as those not undergoing reoperation for nonunion and with documented healing or an mRUST score of \u226512 at final follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Outcome Measures and Comparisons:<\/jats:title>\n                    <jats:p>Total mRUST (scale: 4\u201316) and combined medial and posterior mRUST (scale: 2-8) scores were compared between nonunion cases and controls. Associations of mRUST scores with nonunion versus healing were estimated using logistic regression with adjustment for sampling distribution and time from surgery to mRUST assessment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>\n                      Thirty distal femur nonunion cases and 60 controls were included (median ages 58 and 63 years; with 70% and 67% women, respectively). The median total mRUST score was 6 (interquartile range 6\u20137) for nonunion cases and 10 (interquartile range 8\u201311) for controls (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001). Each 1-point increase in mRUST score was associated with a 57% reduction in odds of nonunion (odds ratio: 0.43, 95% confidence interval: 0.24\u20130.66; area under the curve 0.91). For the combined medial and posterior cortex scores, each 1-point increase was associated with a 70% reduction in odds of nonunion (odds ratio: 0.30, 95% confidence interval: 0.12\u20130.61; area under the curve 0.84).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>mRUST scores between 6 and 12 weeks demonstrated strong association with nonunion versus healing after LLP of distal femur fractures. This was consistent in analysis limited to medial and posterior cortices, although wide confidence intervals suggest imprecision in the effect estimate. Early mRUST assessment may serve as a helpful adjunct to support clinical decision making and patient counseling after LLP of distal femur fractures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>LEVEL OF EVIDENCE:<\/jats:title>\n                    <jats:p>Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1097\/bot.0000000000003136","type":"journal-article","created":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T16:01:18Z","timestamp":1765296078000},"page":"237-244","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Are 6- to 12-Week Radiographic Union Scores Associated With Healing After Lateral Locked Plating of Distal Femur Fractures?"],"prefix":"10.1097","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7031-1643","authenticated-orcid":false,"given":"Robert K.","family":"Wagner","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston, MA;"},{"name":"Harvard Medical School Orthopaedic Trauma Initiative, Boston, MA;"},{"name":"Department of Orthopedic Surgery and Sports Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands;"},{"name":"Amsterdam Movement Sciences, Musculoskeletal Health, Amsterdam, the Netherlands;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-5443-2591","authenticated-orcid":false,"given":"Jacob S.","family":"Borgida","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston, MA;"},{"name":"Harvard Medical School Orthopaedic Trauma Initiative, Boston, MA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-7530-3420","authenticated-orcid":false,"given":"Carla H.","family":"Lehle","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston, MA;"},{"name":"Harvard Medical School Orthopaedic Trauma Initiative, Boston, MA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-3666-6287","authenticated-orcid":false,"given":"Adam N.","family":"Musick","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston, MA;"},{"name":"Harvard Medical School Orthopaedic Trauma Initiative, Boston, MA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alice W.","family":"Wong","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston, MA;"},{"name":"Harvard Medical School Orthopaedic Trauma Initiative, Boston, MA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Healy","family":"Vise","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston, MA;"},{"name":"Harvard Medical School Orthopaedic Trauma Initiative, Boston, MA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1270-2742","authenticated-orcid":false,"given":"Job N.","family":"Doornberg","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands;"},{"name":"Department of Orthopaedic Trauma Surgery, Flinders University Medical Center, Adelaide, Australia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7271-5580","authenticated-orcid":false,"given":"Derek S.","family":"Stenquist","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston, MA;"},{"name":"Harvard Medical School Orthopaedic Trauma Initiative, Boston, MA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9420-2732","authenticated-orcid":false,"given":"Frank F.A.","family":"IJpma","sequence":"additional","affiliation":[{"name":"Department of Trauma Surgery, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3939-7765","authenticated-orcid":false,"given":"Stein J.","family":"Janssen","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery and Sports Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands;"},{"name":"Amsterdam Movement Sciences, Musculoskeletal Health, Amsterdam, the Netherlands;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0011-1184","authenticated-orcid":false,"given":"Arun","family":"Aneja","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston, MA;"},{"name":"Harvard Medical School Orthopaedic Trauma Initiative, Boston, MA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6208-5490","authenticated-orcid":false,"given":"Thuan V.","family":"Ly","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston, MA;"},{"name":"Harvard Medical School Orthopaedic Trauma Initiative, Boston, MA;"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-20260420","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.2174\/1874325001711011277","article-title":"The epidemiology of adult distal femoral shaft fractures in a central London major trauma centre over five years","volume":"11","author":"Khan","year":"2017","journal-title":"Open Orthop J."},{"key":"R2-20260420","doi-asserted-by":"crossref","first-page":"e867","DOI":"10.5435\/JAAOS-D-17-00706","article-title":"Modern implant options for the treatment of distal femur 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