{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T13:00:06Z","timestamp":1790168406003,"version":"4.1.0"},"reference-count":0,"publisher":"Ovid Technologies (Wolters Kluwer Health)","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,9,23]]},"abstract":"<jats:sec>\n                    <jats:title>OBJECTIVES:<\/jats:title>\n                    <jats:p>To determine whether circumferential cerclage wiring for fracture reduction during lateral locked plating (LLP) of Vancouver B1 and C periprosthetic femur fractures is associated with nonunion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>\n                      <jats:italic toggle=\"yes\">Design<\/jats:italic>\n                      : Retrospective cohort study.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting:<\/jats:title>\n                    <jats:p>Three academic Level I trauma centers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patient Selection Criteria:<\/jats:title>\n                    <jats:p>Patients aged &gt;50 years with a Vancouver B1 or C periprosthetic femur fracture (OTA\/AO IV.3B1 and IV.3C) who underwent open reduction and internal fixation with a single LLP with or without circumferential cerclage for fracture reduction from 2010-2023 were included.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Outcome Measures and Comparisons:<\/jats:title>\n                    <jats:p>The primary outcome was nonunion. The association between cerclage use and nonunion was assessed using multivariable logistic regression controlling for age, sex, ASA classification, and Vancouver classification. Secondary outcomes included deep infection and implant revision.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>\n                      141 patients were included: 102 patients (72%; median age 78 years [IQR, 70-87]; 67% female) were treated with cerclage for fracture reduction and 39 patients (28%; median age 82 years [IQR, 70-89]; 85% female) were not. More patients treated with cerclage sustained a Vancouver B1 than Vancouver C fracture (n=78\/102 [76%] vs. n=24\/39 [24%];\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt;0.001). Plates were longer (16 holes [IQR, 13-18] vs. 14 holes [IQR, 13-16];\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      =0.02), stainless steel (n=91\/102 [89%] vs. n=27\/39 [69%];\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt;0.01), and used in neutralization mode (n=96\/102 [94%] vs. n=28\/39 [72%];\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      =0.001) in patients treated with cerclage. Nonunion occurred in 4 patients (4%) treated with cerclage and 4 patients (10%) without (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      =0.30). Cerclage use was not associated with developing nonunion in multivariable regression (adjusted odds ratio, 0.3; 95% CI, 0.1-1.8;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      =0.19). Infection occurred in 6 patients (6%) treated with cerclage and 0 patients (0%) without (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      =0.28). Implant revision occurred in 8 patients (8%) treated with cerclage and 6 patients (15%) without (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      =0.31).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>While baseline between-group differences were noted in Vancouver classification, the judicious use of circumferential cerclage wiring for fracture reduction and stabilization in Vancouver B and C periprosthetic femur fractures with stable implants was not associated with nonunion. No differences were noted in incidence of deep infection or implant revision following cerclage use in this population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>LEVEL OF EVIDENCE:<\/jats:title>\n                    <jats:p>Therapeutic Level III.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1097\/bot.0000000000003285","type":"journal-article","created":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T12:00:09Z","timestamp":1790164809000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Cerclage for Fracture Reduction is Not Associated with Nonunion in Vancouver B or C Periprosthetic Femur Fractures with Stable Implants: A Multicenter Retrospective Study"],"prefix":"10.1097","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8821-6866","authenticated-orcid":false,"given":"Christopher R.","family":"Leland","sequence":"first","affiliation":[{"name":"Harvard Medical School Orthopaedic Trauma Initiative, Boston, MA, USA."},{"name":"Harvard Combined Orthopaedic Residency Program, Harvard Medical School, Boston, MA, USA."},{"name":"Department of Orthopaedic Surgery, Massachusetts General Hospital, Mass General Brigham, Harvard Medical School, Boston, MA, USA."},{"name":"Department of Orthopaedic Surgery, Brigham and Women\u2019s Hospital, Mass General Brigham, Harvard Medical School, Boston, MA, USA."},{"name":"Carl J. Shapiro Department of Orthopaedic Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-3580-7715","authenticated-orcid":false,"given":"Alice W.","family":"Wong","sequence":"additional","affiliation":[{"name":"Harvard Medical School Orthopaedic Trauma Initiative, Boston, MA, USA."},{"name":"Department of Orthopaedic Surgery, Massachusetts General Hospital, Mass General Brigham, Harvard Medical School, Boston, MA, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-7530-3420","authenticated-orcid":false,"given":"Carla H.","family":"Lehle","sequence":"additional","affiliation":[{"name":"Harvard Medical School Orthopaedic Trauma Initiative, Boston, MA, USA."},{"name":"Department of Orthopaedic Surgery, Massachusetts General Hospital, Mass General Brigham, Harvard Medical School, Boston, MA, USA."},{"name":"Department of Orthopaedic Surgery, University Medical Center Groningen, Groningen, The Netherlands."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7031-1643","authenticated-orcid":false,"given":"Robert K.","family":"Wagner","sequence":"additional","affiliation":[{"name":"Harvard Medical School Orthopaedic Trauma Initiative, Boston, MA, USA."},{"name":"Department of Orthopaedic Surgery, Massachusetts General Hospital, Mass General Brigham, Harvard Medical School, Boston, MA, USA."},{"name":"Department of Orthopaedic Surgery, University Medical Center Groningen, Groningen, The Netherlands."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phillip T.","family":"Grisdela","sequence":"additional","affiliation":[{"name":"Harvard Medical School Orthopaedic Trauma Initiative, Boston, MA, USA."},{"name":"Harvard Combined Orthopaedic Residency Program, Harvard Medical School, Boston, MA, USA."},{"name":"Department of Orthopaedic Surgery, Massachusetts General Hospital, Mass General Brigham, Harvard Medical School, Boston, MA, USA."},{"name":"Department of Orthopaedic Surgery, Brigham and Women\u2019s Hospital, Mass General Brigham, Harvard Medical School, Boston, MA, USA."},{"name":"Carl J. Shapiro Department of Orthopaedic Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-5443-2591","authenticated-orcid":false,"given":"Jacob S.","family":"Borgida","sequence":"additional","affiliation":[{"name":"Harvard Medical School Orthopaedic Trauma Initiative, Boston, MA, USA."},{"name":"Department of Orthopaedic Surgery, Massachusetts General Hospital, Mass General Brigham, Harvard Medical School, Boston, MA, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1507-6863","authenticated-orcid":false,"given":"Arun","family":"Aneja","sequence":"additional","affiliation":[{"name":"Harvard Medical School Orthopaedic Trauma Initiative, Boston, MA, USA."},{"name":"Department of Orthopaedic Surgery, Massachusetts General Hospital, Mass General Brigham, Harvard Medical School, Boston, MA, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6208-5490","authenticated-orcid":false,"given":"Thuan V.","family":"Ly","sequence":"additional","affiliation":[{"name":"Harvard Medical School Orthopaedic Trauma Initiative, Boston, MA, USA."},{"name":"Department of Orthopaedic Surgery, Massachusetts General Hospital, Mass General Brigham, Harvard Medical School, Boston, MA, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1608-159X","authenticated-orcid":false,"given":"Nishant","family":"Suneja","sequence":"additional","affiliation":[{"name":"Harvard Medical School Orthopaedic Trauma Initiative, Boston, MA, USA."},{"name":"Carl J. Shapiro Department of Orthopaedic Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4297-225X","authenticated-orcid":false,"given":"John J.","family":"Wixted","sequence":"additional","affiliation":[{"name":"Harvard Medical School Orthopaedic Trauma Initiative, Boston, MA, USA."},{"name":"Carl J. Shapiro Department of Orthopaedic Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5093-7200","authenticated-orcid":false,"given":"Paul T.","family":"Appleton","sequence":"additional","affiliation":[{"name":"Harvard Medical School Orthopaedic Trauma Initiative, Boston, MA, USA."},{"name":"Carl J. Shapiro Department of Orthopaedic Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8217-0593","authenticated-orcid":false,"given":"Edward K.","family":"Rodriguez","sequence":"additional","affiliation":[{"name":"Harvard Medical School Orthopaedic Trauma Initiative, Boston, MA, USA."},{"name":"Carl J. Shapiro Department of Orthopaedic Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7003-6138","authenticated-orcid":false,"given":"Mitchel B.","family":"Harris","sequence":"additional","affiliation":[{"name":"Harvard Medical School Orthopaedic Trauma Initiative, Boston, MA, USA."},{"name":"Department of Orthopaedic Surgery, Massachusetts General Hospital, Mass General Brigham, Harvard Medical School, Boston, MA, USA."},{"name":"Department of Orthopaedic Surgery, Brigham and Women\u2019s Hospital, Mass General Brigham, Harvard Medical School, Boston, MA, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1062-8144","authenticated-orcid":false,"given":"Michael J.","family":"Weaver","sequence":"additional","affiliation":[{"name":"Harvard Medical School Orthopaedic Trauma Initiative, Boston, MA, USA."},{"name":"Department of Orthopaedic Surgery, Massachusetts General Hospital, Mass General Brigham, Harvard Medical School, Boston, MA, USA."},{"name":"Department of Orthopaedic Surgery, Brigham and Women\u2019s Hospital, Mass General Brigham, Harvard Medical School, Boston, MA, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arvind G.","family":"von Keudell","sequence":"additional","affiliation":[{"name":"Harvard Medical School Orthopaedic Trauma Initiative, Boston, MA, USA."},{"name":"Department of Orthopaedic Surgery, Brigham and Women\u2019s Hospital, Mass General Brigham, Harvard Medical School, Boston, MA, USA."},{"name":"Department of Orthopaedic Surgery, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7271-5580","authenticated-orcid":false,"given":"Derek S.","family":"Stenquist","sequence":"additional","affiliation":[{"name":"Harvard Medical School Orthopaedic Trauma Initiative, Boston, MA, USA."},{"name":"Department of Orthopaedic Surgery, Massachusetts General Hospital, Mass General Brigham, Harvard Medical School, Boston, MA, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","container-title":["Journal of Orthopaedic Trauma"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.1097\/BOT.0000000000003285","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T12:00:10Z","timestamp":1790164810000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.1097\/BOT.0000000000003285"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,23]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1097\/bot.0000000000003285","relation":{},"ISSN":["0890-5339","1531-2291"],"issn-type":[{"value":"0890-5339","type":"print"},{"value":"1531-2291","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,23]]}}}