{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T21:47:47Z","timestamp":1792792067902,"version":"4.5.0"},"reference-count":27,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,10]]},"DOI":"10.1097\/bot.0b013e31828d92ee","type":"journal-article","created":{"date-parts":[[2013,2,27]],"date-time":"2013-02-27T12:50:02Z","timestamp":1361969402000},"page":"552-557","source":"Crossref","is-referenced-by-count":56,"title":["Prophylactic Antibiotics in Open Fractures"],"prefix":"10.1097","volume":"27","author":[{"given":"Carla C.","family":"Saveli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven J.","family":"Morgan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert W.","family":"Belknap","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erin","family":"Ross","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip F.","family":"Stahel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George W.","family":"Chaus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J.","family":"Hak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Walter L.","family":"Biffl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bryan","family":"Knepper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Connie S.","family":"Price","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R2-2-20210212","doi-asserted-by":"crossref","first-page":"453","DOI":"10.2106\/00004623-197658040-00004","article-title":"Prevention of infection in the treatment of one thousand and twenty-five open fractures of long bones: retrospective and prospective analyses.","volume":"58","author":"Gustilo","year":"1976","journal-title":"J Bone Joint Surg Am"},{"key":"R3-2-20210212","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1097\/00005373-198408000-00009","article-title":"Problems in the management of type III (severe) open fractures: a new classification of type III open fractures.","volume":"24","author":"Gustilo","year":"1984","journal-title":"J Trauma"},{"key":"R4-2-20210212","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1097\/00005131-198701010-00002","article-title":"A double-blind clinical trial of prophylactic cloxacillin in open fractures.","volume":"1","author":"Braun","year":"1987","journal-title":"J Orthop Trauma"},{"key":"R5-2-20210212","doi-asserted-by":"crossref","first-page":"57","DOI":"10.3109\/17453678208992179","article-title":"Antibiotic prophylaxis in open and closed fractures: a controlled clinical trial.","volume":"53","author":"Bergman","year":"1982","journal-title":"Acta Orthop"},{"key":"R6-2-20210212","doi-asserted-by":"crossref","first-page":"532","DOI":"10.2106\/00004623-197456030-00010","article-title":"The role of antibiotics in the management of open fractures.","volume":"56","author":"Patzakis","year":"1974","journal-title":"J Bone Joint Surg Am"},{"key":"R7-2-20210212","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1097\/00003086-198611000-00031","article-title":"Orthopedic experience with methicillin-resistant Staphylococcus aureus during a hospital epidemic.","volume":"212","author":"Johnson","year":"1986","journal-title":"Clin Orthop Relat Res"},{"key":"R8-2-20210212","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1086\/423965","article-title":". Natural history of community-acquired methicillin-resistant Staphylococcus aureus colonization and infection in soldiers.","volume":"39","author":"Ellis","year":"2004","journal-title":"Clin Infect Dis"},{"key":"R9-2-20210212","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1089\/sur.2006.7.379","article-title":"Council of the Surgical Infection Society. Surgical Infection Society guideline: prophylactic antibiotic use in open fractures: an evidence-based guideline.","volume":"7","author":"Hauser","year":"2006","journal-title":"Surg Infect (Larchmt)"},{"key":"R10-2-20210212","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1093\/clinids\/18.3.422","article-title":". Quality standard for antimicrobial prophylaxis in surgical procedures. Infectious Diseases Society of America.","volume":"18","author":"Dellinger","year":"1994","journal-title":"Clin Infect Dis"},{"key":"R11-2-20210212","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1086\/501763","article-title":"MD, van Nieuwland-Bollen E, Bogaers-Hofman D, et al.. Nasal carriage of Staphylococcus aureus is a major risk factor for surgical-site infections in orthopedic surgery.","volume":"21","year":"2000","journal-title":"Infect Control Hosp Epidemiol"},{"key":"R12-2-20210212","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1302\/0301-620X.91B2.21715","article-title":". Incidence of MRSA surgical-site infection in MRSA carriers in an orthopaedic trauma unit.","volume":"91","author":"Shukla","year":"2009","journal-title":"J Bone Joint Surg Br"},{"key":"R13-2-20210212","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1086\/367653","article-title":". Adverse clinical and economic outcomes attributable to methicillin resistance among patients with Staphylococcus aureus surgical site infection.","volume":"36","author":"Engemann","year":"2003","journal-title":"Clin Infect Dis"},{"key":"R14-2-20210212","doi-asserted-by":"crossref","first-page":"e8305","DOI":"10.1371\/journal.pone.0008305","article-title":". Clinical and financial outcomes due to methicillin resistant Staphylococcus aureus surgical site infection: a multi-center matched outcomes study.","volume":"4","author":"Anderson","year":"2009","journal-title":"PLoS One"},{"key":"R15-2-20210212","doi-asserted-by":"crossref","first-page":"1820","DOI":"10.2106\/JBJS.I.01050","article-title":". Institutional prescreening for detection and eradication of methicillin-resistant Staphylococcus aureus in patients undergoing elective orthopaedic surgery.","volume":"92","author":"Kim","year":"2010","journal-title":"J Bone Joint Surg Am"},{"key":"R16-2-20210212","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1093\/jac\/dki372","article-title":". Guidelines for the laboratory diagnosis and susceptibility testing of methicillin-resistant Staphylococcus aureus (MRSA).","volume":"56","author":"Brown","year":"2005","journal-title":"J Antimicrob Chemother"},{"key":"R17-2-20210212","doi-asserted-by":"crossref","first-page":"606","DOI":"10.2307\/30148464","article-title":". CDC definitions of nosocomial surgical site infections, 1992: a modification of CDC definitions of surgical wound infections.","volume":"13","author":"Horan","year":"1992","journal-title":"Infect Control Hosp Epidemiol"},{"key":"R18-2-20210212","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1093\/jac\/dkp030","article-title":"Methodological issues regarding safety evaluation in randomized controlled trials of the effectiveness of antibiotic prophylaxis for the prevention of post-operative wound infection: systematic review.","volume":"63","author":"Yiannakopoulou","year":"2009","journal-title":"J Antimicrob Chemother"},{"key":"R19-2-20210212","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1037\/a0012850","article-title":". Comparisons of methods for multiple hypothesis testing in neuropsychological research.","volume":"23","author":"Blakesley","year":"2009","journal-title":"Neuropsychology"},{"key":"R20-2-20210212","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1086\/502229","article-title":". Rates of carriage of methicillin-resistant and methicillin-susceptible Staphylococcus aureus in an outpatient population.","volume":"24","author":"Kenner","year":"2003","journal-title":"Infect Control Hosp Epidemiol"},{"key":"R21-2-20210212","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1086\/502033","article-title":". The impact of surgical-site infections following orthopedic surgery at a community hospital and a university hospital: adverse quality of life, excess length of stay, and extra cost.","volume":"23","author":"Whitehouse","year":"2002","journal-title":"Infect Control Hosp Epidemiol"},{"key":"R22-2-20210212","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1097\/00003086-199706000-00010","article-title":"Efficacy of cultures in the management of open fractures.","volume":"339","author":"Lee","year":"1997","journal-title":"Clin Orthop Relat Res"},{"key":"R23-2-20210212","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1001\/archsurg.1988.01400270067010","article-title":". Duration of preventive antibiotic administration for open extremity fractures.","volume":"123","author":"Dellinger","year":"1988","journal-title":"Arch Surg"},{"key":"R24-2-20210212","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1097\/00003086-198906000-00006","article-title":"Factors influencing infection rate in open fracture wounds.","volume":"243","author":"Patzakis","year":"1989","journal-title":"Clin Orthop Relat Res"},{"key":"R25-2-20210212","doi-asserted-by":"crossref","first-page":"881","DOI":"10.3201\/eid0809.020063","article-title":"Biofilms: microbial life on surfaces.","volume":"8","author":"Donlan","year":"2002","journal-title":"Emerg Infect Dis"},{"key":"R26-2-20210212","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1007\/PL00015012","article-title":". Epidemiology of bacterial infection during management of open leg fractures.","volume":"18","author":"Carsenti-Etesse","year":"1999","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"R27-2-20210212","doi-asserted-by":"crossref","first-page":"611","DOI":"10.3928\/01477447-20110627-25","article-title":". The role of prophylactic antibiotics in open fractures in an era of community-acquired methicillin-resistant Staphylococcus aureus.","volume":"34","author":"Saveli","year":"2011","journal-title":"Orthopedics"},{"key":"R28-2-20210212","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1086\/383318","article-title":". Glycopeptides are no more effective than beta-lactam agents for prevention of surgical site infection after cardiac surgery: a meta-analysis.","volume":"38","author":"Bolon","year":"2004","journal-title":"Clin Infect Dis"}],"container-title":["Journal of Orthopaedic Trauma"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/BOT.0b013e31828d92ee","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,9]],"date-time":"2022-02-09T15:42:48Z","timestamp":1644421368000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00005131-201310000-00002"}},"subtitle":["A Pilot Randomized Clinical Safety Study"],"short-title":[],"issued":{"date-parts":[[2013,10]]},"references-count":27,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2013]]}},"URL":"https:\/\/doi.org\/10.1097\/bot.0b013e31828d92ee","relation":{},"ISSN":["0890-5339"],"issn-type":[{"value":"0890-5339","type":"print"}],"subject":[],"published":{"date-parts":[[2013,10]]}}}