{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T15:55:32Z","timestamp":1790610932966,"version":"4.1.0"},"reference-count":22,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,2,15]]},"abstract":"<jats:sec>\n                    <jats:title>Study Design.<\/jats:title>\n                    <jats:p>Retrospective multicenter study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective.<\/jats:title>\n                    <jats:p>We reviewed 15-year trends in operative factors, radiographic and quality of life outcomes, and complication rates in children with cerebral palsy (CP)-related scoliosis who underwent spinal fusion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Summary of Background Data.<\/jats:title>\n                    <jats:p>Over the past two decades, significant efforts have been made to decrease complications and improve outcomes of this population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods.<\/jats:title>\n                    <jats:p>We retrospectively reviewed a multicenter registry of pediatric CP patients who underwent spinal fusion from 2008 to 2020. We evaluated baseline and operative, hospitalization, and complication data as well as radiographic and quality of life outcomes at a minimum 2-year follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results.<\/jats:title>\n                    <jats:p>\n                      Mean estimated blood loss and transfusion volume declined from 2.7\u00b12.0\u00a0L in 2008 to 0.71\u00b10.34\u00a0L in 2020 and 1.0\u00b10.5\u00a0L in 2008 to 0.5\u00b10.2\u00a0L in 2020, respectively, with a concomitant increase in antifibrinolytic use from 58% to 97% (all,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt;0.01). Unit rod and pelvic fusion use declined from 33% in 2008 to 0% in 2020 and 96% in 2008 to 79% in 2020, respectively (both,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt;0.05). Mean postoperative intubation time declined from 2.5\u00b12.6 to 0.42\u00b10.63 days (\n                      <jats:italic toggle=\"yes\">P&lt;<\/jats:italic>\n                      0.01). No changes were observed in preoperative and postoperative coronal angle and pelvic obliquity, operative time, frequency of anterior\/anterior-posterior approach, and durations of hospital and intensive care unit stays. Improvements in the Caregiver Priorities and Child Health Index of Life with Disabilities postoperatively did not change significantly over the study period. Complication rates, including reoperation, superficial and deep surgical site infection, and gastrointestinal and medical complications remained stable over the study period.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions.<\/jats:title>\n                    <jats:p>Over the past 15 years of CP scoliosis surgery, surgical blood loss, transfusion volumes, duration of postoperative intubation, and pelvic fusion rates have decreased. However, the degree of radiographic correction, the rates of surgical and medical complications (including infection), and health-related quality of life measures have broadly remained constant.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1097\/brs.0000000000004792","type":"journal-article","created":{"date-parts":[[2023,11,22]],"date-time":"2023-11-22T08:01:35Z","timestamp":1700640095000},"page":"247-254","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":9,"title":["Fifteen Years of Spinal Fusion Outcomes in Children With Cerebral Palsy"],"prefix":"10.1097","volume":"49","author":[{"given":"Daniel","family":"Badin","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, The Johns Hopkins University, Baltimore, MD"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suken A.","family":"Shah","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Nemours\/Alfred I. DuPont Hospital for Children, Wilmington, DE"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Unni G.","family":"Narayanan","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, University of Toronto and The Hospital for Sick Children, Toronto, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick J.","family":"Cahill","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Children\u2019s Hospital of Philadelphia, Philadelphia, PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Majd","family":"Marrache","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, The Johns Hopkins University, Baltimore, MD"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amer F.","family":"Samdani","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Shriners Hospitals for Children, Philadelphia, PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Burt","family":"Yaszay","sequence":"additional","affiliation":[{"name":"Department of Orthopedics and Sports Medicine, Seattle Children\u2019s Hospital and University of Washington, Seattle, WA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joann B.","family":"Hunsberger","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle C.","family":"Marks","sequence":"additional","affiliation":[{"name":"Setting Scoliosis Straight, El Cajon, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"HARMS Study Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul D.","family":"Sponseller","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic 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