{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T21:14:58Z","timestamp":1770498898680,"version":"3.49.0"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:p>Metastatic bone disease of the radius is rare, but the functional loss of an upper extremity can profoundly impact patient quality of life and hinder independent living. When the mechanical stability of the radius is compromised, surgical intervention such as intramedullary (IM) nailing or plating may be considered in combination with radiation therapy (RT) to alleviate pain, control local tumor progression, and provide immediate stability to the bone. There are several limitations to traditional metallic IM nails, such as limited use in adults, complicated postoperative CT planning for RT, the obscuring of local tumor recurrence or progression, and metal scattering that affects RT dosing. Photodynamic nail IM stabilization is a novel, minimally invasive surgical technique that circumvents several of these shortcomings, in which a photocurable monomer is introduced through a balloon that can conform to the irregularities of an osteolytic metastatic lesion. We describe the photodynamic nail technique for the treatment of impending and\/or pathologic fractures of the proximal radius.<\/jats:p>","DOI":"10.1097\/bth.0000000000000513","type":"journal-article","created":{"date-parts":[[2025,3,30]],"date-time":"2025-03-30T16:34:25Z","timestamp":1743352465000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Management of Impending and\/or Pathologic Fractures of the Proximal Radius in the Setting of Metastatic Bone Disease With an Intramedullary Photodynamic Nail"],"prefix":"10.1097","volume":"29","author":[{"given":"Megan H.","family":"Goh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah E.","family":"Ballatori","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcos R.","family":"Gonzalez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0681-9004","authenticated-orcid":false,"given":"Santiago A.","family":"Lozano-Calderon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","published-online":{"date-parts":[[2025,6]]},"reference":[{"key":"R1-20250520","doi-asserted-by":"crossref","first-page":"17","DOI":"10.3322\/caac.21763","article-title":"Cancer statistics, 2023","volume":"73","author":"Siegel","year":"2023","journal-title":"CA Cancer J Clin"},{"key":"R2-20250520","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1016\/S0030-5898(05)70182-6","article-title":"Management of metastatic disease of other bones","volume":"31","author":"Esther","year":"2000","journal-title":"Orthop Clin North Am"},{"key":"R3-20250520","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1007\/s00590-013-1311-1","article-title":"Acrometastases","volume":"24","author":"Mavrogenis","year":"2014","journal-title":"Eur J Orthop Surg Traumatol"},{"key":"R4-20250520","doi-asserted-by":"crossref","first-page":"807","DOI":"10.3928\/01477447-20100924-29","article-title":"Treatment of metastatic bone lesions in the upper extremity: indications for surgery","volume":"33","author":"Muramatsu","year":"2010","journal-title":"Orthopedics"},{"key":"R5-20250520","doi-asserted-by":"crossref","first-page":"e116","DOI":"10.5435\/JAAOS-D-20-00819","article-title":"Management of metastatic disease of the upper extremity","volume":"29","author":"Voskuil","year":"2021","journal-title":"J Am Acad Orthop Surg"},{"key":"R6-20250520","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1097\/BOT.0000000000002360","article-title":"Management of metastatic disease in long bones","volume":"36","author":"Auran","year":"2022","journal-title":"J Orthop Trauma"},{"key":"R7-20250520","doi-asserted-by":"crossref","first-page":"83","DOI":"10.4103\/0019-5413.143915","article-title":"Management of skeletal metastases: an orthopaedic surgeon\u2019s guide","volume":"49","author":"Agarwal","year":"2015","journal-title":"Indian J Orthop"},{"key":"R8-20250520","doi-asserted-by":"crossref","first-page":"4081","DOI":"10.1245\/s10434-014-4002-1","article-title":"Surgical management of bone metastases: quality of evidence and systematic review","volume":"21","author":"Wood","year":"2014","journal-title":"Ann Surg Oncol"},{"key":"R9-20250520","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1302\/2058-5241.1.000008","article-title":"Treatment of pathological fractures of the long bones","volume":"1","author":"Willeumier","year":"2016","journal-title":"EFORT Open Rev"},{"key":"R10-20250520","doi-asserted-by":"crossref","first-page":"2286","DOI":"10.1016\/j.jse.2023.04.023","article-title":"Titanium vs. carbon fiber-reinforced intramedullary nailing for humeral bone tumors","volume":"32","author":"Bhashyam","year":"2023","journal-title":"J Shoulder Elbow Surg"},{"key":"R11-20250520","doi-asserted-by":"crossref","first-page":"154","DOI":"10.3928\/01477447-20210416-06","article-title":"Early experience in pathologic humerus fracture treated with the photodynamic bone stabilization system shows limitations related to patient selection","volume":"44","author":"Krumme","year":"2021","journal-title":"Orthopedics"},{"key":"R12-20250520","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1186\/s12891-020-03927-6","article-title":"The IlluminOss photodynamic bone stabilization system for pathological osteolyses and fractures of the humerus: indications, advantages and limits in a series of 12 patients at 24 months of minimum follow-up","volume":"22","author":"Zoccali","year":"2021","journal-title":"BMC Musculoskelet Disord"},{"key":"R13-20250520","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1530\/EOR-21-0119","article-title":"Surgical management options for long-bone metastasis","volume":"7","author":"Cirstoiu","year":"2022","journal-title":"EFORT Open Rev"},{"key":"R14-20250520","doi-asserted-by":"crossref","first-page":"100352","DOI":"10.1016\/j.jbo.2021.100352","article-title":"Surgical outcomes of metastatic bone tumors in the extremities (surgical outcomes of bone metastases)","volume":"27","author":"Hara","year":"2021","journal-title":"J Bone Oncol"},{"key":"R15-20250520","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.jmbbm.2018.03.008","article-title":"Glass -polyalkenoate cement: an alternative material for kyphoplasty in osteoporotic vertebral compression fractures \u2013 an ex vivo study","volume":"83","author":"Leschinger","year":"2018","journal-title":"J Mech Behav Biomed Mater"},{"key":"R17-20250520","doi-asserted-by":"crossref","first-page":"2309499020915989","DOI":"10.1177\/2309499020915989","article-title":"Incidence, prevalence, and outcomes of systemic malignancy with bone metastases","volume":"28","author":"Jiang","year":"2020","journal-title":"J Orthop Surg (Hong Kong)"},{"key":"R18-20250520","doi-asserted-by":"crossref","first-page":"2510","DOI":"10.3390\/ma13112510","article-title":"Enhancing the mechanical properties of glass-ionomer dental cements: a review","volume":"13","author":"Nicholson","year":"2020","journal-title":"Materials (Basel)"},{"key":"R19-20250520","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/S1348-8643(18)30005-3","article-title":"Unraveling the mechanical strength of biomaterials used as a bone scaffold in oral and maxillofacial defects","volume":"15","author":"Prasadh","year":"2018","journal-title":"Oral Sci Int"},{"key":"R20-20250520","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1097\/00003086-198309000-00041","article-title":"Fracture healing in metastatic bone disease","author":"Gainor","year":"1983","journal-title":"Clin Orthop Relat Res"},{"key":"R21-20250520","doi-asserted-by":"crossref","first-page":"5","DOI":"10.17140\/ORTOJ-1-102","article-title":"A biomechanical comparison of a novel expandable photodynamic intramedullary system to a metal plate and screw system in humerus and femur osteotomy models","volume":"1","author":"Johnston","year":"2016","journal-title":"Orthop Res Traumatol Open J"}],"container-title":["Techniques in Hand &amp; Upper Extremity Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/BTH.0000000000000513","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,20]],"date-time":"2025-05-20T16:00:40Z","timestamp":1747756840000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.1097\/BTH.0000000000000513"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,28]]},"references-count":20,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.1097\/bth.0000000000000513","relation":{},"ISSN":["1531-6572"],"issn-type":[{"value":"1531-6572","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,28]]}}}