{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:32:48Z","timestamp":1786120368092,"version":"build-2736575974"},"reference-count":35,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,8]]},"DOI":"10.1097\/cad.0b013e3283512a68","type":"journal-article","created":{"date-parts":[[2012,4,3]],"date-time":"2012-04-03T10:08:03Z","timestamp":1333447683000},"page":"713-717","source":"Crossref","is-referenced-by-count":1,"title":["Pharmacokinetic evaluation of pancreatic arterial infusion chemotherapy with lipid emulsion as a drug carrier in an animal model"],"prefix":"10.1097","volume":"23","author":[{"given":"Qiang","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mao-Qiang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng","family":"Duan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liu-Xin","family":"Duan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guo-Kun","family":"Ao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-6-20210227","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1097\/01.mpa.0000168220.97967.d1","article-title":"Current diagnosis and treatment of pancreatic cancer in China.","volume":"31","author":"Guo","year":"2005","journal-title":"Pancreas"},{"key":"R2-6-20210227","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/1476-4598-2-14","article-title":"Invasion and metastasis in pancreatic cancer.","volume":"2","author":"Keleg","year":"2003","journal-title":"Mol Cancer"},{"key":"R3-6-20210227","first-page":"483","article-title":"Carcinoma of pancreas: critical analysis of cost, results of resection, and the need for standardized reporting.","volume":"181","author":"Gudjonsson","year":"1995","journal-title":"J Am Coll Surg"},{"key":"R4-6-20210227","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1056\/NEJMoa032295","article-title":"A randomized trial of chemoradiotherapy and chemotherapy after resection of pancreatic cancer.","volume":"350","author":"Neoptolemos","year":"2004","journal-title":"N Engl J Med"},{"key":"R5-6-20210227","doi-asserted-by":"crossref","first-page":"5","DOI":"10.3322\/canjclin.53.1.5","article-title":"Cancer statistics, 2003.","volume":"53","author":"Jemal","year":"2003","journal-title":"CA Cancer J Clin"},{"key":"R6-6-20210227","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1016\/S1091-255X(00)80105-5","article-title":"Resected adenocarcinoma of the pancreas-616 patients: results, outcomes, and prognostic indicators.","volume":"4","author":"Sohn","year":"2000","journal-title":"J Gastrointest Surg"},{"key":"R7-6-20210227","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1097\/COC.0b013e31807a328c","article-title":"Intra-arterial infusion chemotherapy with 5-fluorouracil and cisplatin in advanced pancreatic cancer: a feasibility study.","volume":"31","author":"Sasada","year":"2008","journal-title":"Am J Clin Oncol"},{"key":"R9-6-20210227","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1245\/ASO.2003.07.018","article-title":"An experimental study on the pharmacokinetics of 5-fluorouracil regional chemotherapy for pancreatic cancer.","volume":"10","author":"Mitsutsuji","year":"2003","journal-title":"Ann Surg Oncol"},{"key":"R10-6-20210227","first-page":"275","article-title":"Clinical study on regional intra-arterial infusion chemotherapy with solvent of lipid emulsion for treatment of locally advanced pancreatic cancer.","volume":"18","author":"Li","year":"2009","journal-title":"J Intervent Radiol"},{"key":"R11-6-20210227","first-page":"217","article-title":"Experimental study on combining femoral artery infusion of high dose cisplatin with hemodialysis in an animal model.","volume":"2","author":"Tang","year":"2003","journal-title":"Chin J Bone Tumor Bone Dis"},{"key":"R12-6-20210227","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1084\/jem.182.1.267","article-title":"Triglyceride-rich lipoproteins prevent septic death in rats.","volume":"182","author":"Read","year":"1995","journal-title":"J Exp Med"},{"key":"R13-6-20210227","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1248\/yakushi.128.269","article-title":"Lipid carriers: a versatile delivery vehicle for proteins and peptides.","volume":"128","author":"Rawat","year":"2008","journal-title":"Yakugaku Zasshi"},{"key":"R14-6-20210227","first-page":"141","article-title":"The blood supply of the pancreas and duodenum in the dog.","volume":"12","author":"Tang","year":"1995","journal-title":"Zhonghua Shi Yan Wai Ke Za Zhi"},{"key":"R15-6-20210227","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.jvir.2009.09.027","article-title":"Pharmacokinetic evaluation of pancreatic arterial infusion chemotherapy after unification of the blood supply in an animal model.","volume":"21","author":"Tanaka","year":"2010","journal-title":"J Vasc Interv Radiol"},{"key":"R16-6-20210227","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1016\/0959-8049(96)00100-1","article-title":"MDR1 gene expression in solid tumours.","volume":"32A","author":"Goldstein","year":"1996","journal-title":"Eur J Cancer"},{"key":"R17-6-20210227","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1093\/jnci\/81.2.116","article-title":"Expression of a multidrug resistance gene in human cancers.","volume":"81","author":"Goldstein","year":"1989","journal-title":"J Natl Cancer Inst"},{"key":"R18-6-20210227","first-page":"338","article-title":"A new method of intra-arterial regional chemotherapy with more selective drug delivery for locally advanced pancreatic cancer.","volume":"43","author":"Ohigashi","year":"1996","journal-title":"Hepatogastroenterology"},{"key":"R19-6-20210227","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/S0748-7983(97)93720-3","article-title":"Palliative and adjuvant regional chemotherapy in pancreatic cancer.","volume":"23","author":"Link","year":"1997","journal-title":"Eur J Surg Oncol"},{"key":"R20-6-20210227","first-page":"479","article-title":"Locoregional chemotherapy in pancreatic cancer.","volume":"46","author":"Nazli","year":"1999","journal-title":"Hepatogastroenterology"},{"key":"R21-6-20210227","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1002\/1097-0142(20000715)89:2<303::AID-CNCR15>3.0.CO;2-1","article-title":"A novel arterial infusion chemotherapy for the treatment of patients with advanced pancreatic carcinoma after vascular supply distribution via superselective embolization.","volume":"89","author":"Homma","year":"2000","journal-title":"Cancer"},{"key":"R22-6-20210227","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1093\/annonc\/mdn640","article-title":"A phase I study of full-dose gemcitabine and regional arterial infusion of nafamostat mesilate for advanced pancreatic cancer.","volume":"20","author":"Uwagawa","year":"2009","journal-title":"Ann Oncol"},{"key":"R23-6-20210227","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1097\/01.mpa.0000158025.46172.ae","article-title":"5-Fluorouracil intra-arterial infusion combined with systemic gemcitabine for unresectable pancreatic cancer.","volume":"30","author":"Takamori","year":"2005","journal-title":"Pancreas"},{"key":"R24-6-20210227","first-page":"831","article-title":"Regional celiac artery infusion in the adjuvant treatment of pancreatic cancer.","volume":"23","author":"Papachristou","year":"2003","journal-title":"Anticancer Res"},{"key":"R25-6-20210227","first-page":"4407","article-title":"Celiac axis infusion and microembolization for advanced stage IIIIV pancreatic cancer: a phase II study on 265 cases.","volume":"25","author":"Aigner","year":"2005","journal-title":"Anticancer Res"},{"key":"R26-6-20210227","doi-asserted-by":"crossref","first-page":"421","DOI":"10.2214\/AJR.07.2279","article-title":"Arterial infusion of 5-fluorouracil combined with concurrent radiotherapy for unresectable pancreatic cancer: results from a pilot study.","volume":"189","author":"Tanaka","year":"2007","journal-title":"AJR"},{"key":"R27-6-20210227","doi-asserted-by":"crossref","first-page":"168","DOI":"10.2214\/AJR.08.1392","article-title":"A novel interventional radiology technique for arterial infusion chemotherapy against advanced pancreatic cancer.","volume":"192","author":"Tanaka","year":"2009","journal-title":"AJR"},{"key":"R28-6-20210227","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1007\/s00270-001-0040-8","article-title":"Oily chemoembolization of pancreatic head adenocarcinoma.","volume":"24","author":"Tarazov","year":"2001","journal-title":"Cardiovasc Intervent Radiol"},{"key":"R29-6-20210227","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1097\/01.RVI.0000131220.07444.7B","article-title":"Catheter position for adequate intraarterial chemotherapy for advanced pancreatic cancer.","volume":"15","author":"Tanaka","year":"2004","journal-title":"J Vasc Interv Radiol"},{"key":"R30-6-20210227","first-page":"3004","article-title":"Expression of vascular permeability factorvascular endothelial growth factor in human hepatocellular carcinoma.","volume":"56","author":"Suzuki","year":"1996","journal-title":"Cancer Res"},{"key":"R31-6-20210227","first-page":"54","article-title":"Development of the targeting effect of lipid emulsion.","volume":"31","author":"Ke","year":"2007","journal-title":"Yao Xue Jin Zhan"},{"key":"R32-6-20210227","first-page":"169","article-title":"Structure and function of pancreatic microcirculation.","volume":"18","author":"Zhou","year":"2001","journal-title":"Sheng Wu Yi Xue Gong Cheng Xue Za Zhi"},{"key":"R33-6-20210227","first-page":"558","article-title":"Progress of drug loaded intravenous lipid emulsions.","volume":"35","author":"Meng","year":"2004","journal-title":"Zhong Guo Yi Yao Gong Ye Za Zhi"},{"key":"R34-6-20210227","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.ejpb.2008.11.012","article-title":"Development of new lipid-based paclitaxel nanoparticles using sequential simplex optimization.","volume":"72","author":"Dong","year":"2009","journal-title":"Eur J Pharm Biopharm"},{"key":"R35-6-20210227","first-page":"526","article-title":"The effect of different concentration of lipid emulsion on blood flow velocity: an experimental study.","volume":"18","author":"Li","year":"2009","journal-title":"J Intervent Radiol"},{"key":"R36-6-20210227","first-page":"67","article-title":"Clinical pharmacokinetics of cis-diamminedichloroplatinum (DDP).","volume":"14","author":"Zhang","year":"1992","journal-title":"Chin J Oncol"}],"container-title":["Anti-Cancer Drugs"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.1097\/CAD.0b013e3283512a68","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T20:35:53Z","timestamp":1786048553000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00001813-201208000-00006"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,8]]},"references-count":35,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2012]]}},"URL":"https:\/\/doi.org\/10.1097\/cad.0b013e3283512a68","relation":{},"ISSN":["0959-4973"],"issn-type":[{"value":"0959-4973","type":"print"}],"subject":[],"published":{"date-parts":[[2012,8]]}}}