{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T03:31:03Z","timestamp":1790220663239,"version":"4.1.0"},"reference-count":50,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","license":[{"start":{"date-parts":[[2019,8,1]],"date-time":"2019-08-01T00:00:00Z","timestamp":1564617600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:sec>\n            <jats:title>Objectives:<\/jats:title>\n            <jats:p>Despite improvements in the management of in-hospital cardiac arrest over the past decade, in-hospital cardiac arrest continues to be associated with poor prognosis. This has led to the development of rapid response systems, hospital-wide efforts to improve patient outcomes by centering on prompt identification of decompensating patients, expert clinical management, and continuous quality improvement of processes of care. The rapid response system may include cardiac arrest teams, which are centered on identification and treatment of patients with in-hospital cardiac arrest. However, few evidence-based guidelines exist to guide the formation of such teams, and the degree of their variation across the United States has not been well described.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Design:<\/jats:title>\n            <jats:p>Descriptive cross-sectional, internet-based survey.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Setting:<\/jats:title>\n            <jats:p>Cohort of preidentified clinicians involved in their hospital\u2019s adult rapid response system across the United States.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Subjects:<\/jats:title>\n            <jats:p>Clinicians who had been identified by study team members using personal and professional contacts over a 7-month period from June 2018 to December 2018.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Interventions:<\/jats:title>\n            <jats:p>An 80-item survey was developed by the investigators. It sought information on the afferent (identification and notification of providers) and efferent (response of providers to patient) limbs of the rapid response system, as well as management of patients post in-hospital cardiac arrest.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Measurements and Main Results:<\/jats:title>\n            <jats:p>One-hundred fourteen surveys were distributed. Of these, 109 (96%) were completed. Six were duplicates and were excluded, leaving a total of 103 surveys from 103 hospitals in 30 states. Seventy-six percent of hospitals were academic, 30% were large hospitals (&gt; 750 inpatient beds), and 58% had large ICUs (&gt; 50 ICU beds). We found wide variation in the structure and function in both the afferent and efferent limbs of the rapid response system. The majority of hospitals had a rapid response team and a cardiac arrest team. Most rapid response teams contained a provider, a critical care nurse, and a respiratory therapist. In hospitals with training programs in internal medicine, anesthesia, emergency medicine, or critical care, 45% of rapid response teams and 75% of cardiac arrest teams were led by trainees, with inconsistent attending presence. Targeted temperature management and coronary catheterization were widely used post in-hospital cardiac arrest, but indications varied considerably.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions:<\/jats:title>\n            <jats:p>We have demonstrated substantial variation in the structure and function of rapid response systems as well as in management of patients during and after in-hospital cardiac arrest.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/cce.0000000000000031","type":"journal-article","created":{"date-parts":[[2019,8,8]],"date-time":"2019-08-08T04:42:46Z","timestamp":1565239366000},"page":"e0031","source":"Crossref","is-referenced-by-count":17,"title":["Rapid Response and Cardiac Arrest Teams: A Descriptive Analysis of 103 American Hospitals"],"prefix":"10.1097","volume":"1","author":[{"given":"Oscar J. L.","family":"Mitchell","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, New York School of Medicine, New York, NY."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline W.","family":"Motschwiller","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, New York School of Medicine, New York, NY."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James M.","family":"Horowitz","sequence":"additional","affiliation":[{"name":"Division of Cardiology, New York School of Medicine, New York, NY."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oren A.","family":"Friedman","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Cedars Sinai, Los Angeles, CA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Graham","family":"Nichol","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Washington, Seattle, WA."},{"name":"Department of Emergency Medicine, University of Washington, Seattle, WA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura E.","family":"Evans","sequence":"additional","affiliation":[{"name":"Medical Director of Critical Care, Bellevue Hospital, New York School of Medicine, New York, NY."},{"name":"Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, New York School of Medicine, New York, NY."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vikramjit","family":"Mukherjee","sequence":"additional","affiliation":[{"name":"Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, New York School of Medicine, New York, NY."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2019,8]]},"reference":[{"key":"R1-20230728","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1001\/jama.299.7.785","article-title":"Survival from in-hospital cardiac arrest during nights and weekends.","volume":"299","author":"Peberdy","year":"2008","journal-title":"JAMA"},{"key":"R2-20230728","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1016\/j.resuscitation.2014.04.002","article-title":"Incidence and outcome of in-hospital cardiac arrest in the United Kingdom National Cardiac Arrest Audit.","volume":"85","author":"Nolan","year":"2014","journal-title":"Resuscitation"},{"key":"R3-20230728","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.resuscitation.2017.10.023","article-title":"Long-term survival trends of medicare patients after in-hospital cardiac arrest: Insights from Get With The Guidelines-Resuscitation\u00ae.","volume":"123","author":"Thompson","year":"2018","journal-title":"Resuscitation"},{"key":"R4-20230728","doi-asserted-by":"crossref","first-page":"1388","DOI":"10.1378\/chest.98.6.1388","article-title":"Clinical antecedents to in-hospital cardiopulmonary arrest.","volume":"98","author":"Schein","year":"1990","journal-title":"Chest"},{"key":"R5-20230728","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/S0300-9572(98)00056-2","article-title":"Can some in-hospital cardio-respiratory arrests be prevented? A prospective survey.","volume":"37","author":"Smith","year":"1998","journal-title":"Resuscitation"},{"key":"R6-20230728","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.resuscitation.2004.05.016","article-title":"A comparison of antecedents to cardiac arrests, deaths and emergency intensive care admissions in Australia and New Zealand, and the United Kingdom\u2013the ACADEMIA study.","volume":"62","author":"Kause","year":"2004","journal-title":"Resuscitation"},{"key":"R7-20230728","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.resuscitation.2009.09.026","article-title":"The impact of rapid response system on delayed emergency team activation patient characteristics and outcomes\u2013a follow-up study.","volume":"81","author":"Calzavacca","year":"2010","journal-title":"Resuscitation"},{"key":"R8-20230728","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1056\/NEJMra0910926","article-title":"Rapid-response teams.","volume":"365","author":"Jones","year":"2011","journal-title":"N Engl J Med"},{"key":"R9-20230728","doi-asserted-by":"crossref","first-page":"2463","DOI":"10.1097\/01.CCM.0000235743.38172.6E","article-title":"Findings of the first consensus conference on medical emergency teams.","volume":"34","author":"Devita","year":"2006","journal-title":"Crit Care Med"},{"key":"R10-20230728","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1007\/s00134-016-4219-5","article-title":"Rapid response teams improve outcomes: Yes.","volume":"42","author":"Jones","year":"2016","journal-title":"Intensive Care Med"},{"key":"R13-20230728","doi-asserted-by":"crossref","first-page":"283","DOI":"10.5694\/j.1326-5377.2003.tb05548.x","article-title":"A prospective before-and-after trial of a medical emergency team.","volume":"179","author":"Bellomo","year":"2003","journal-title":"Med J Aust"},{"key":"R14-20230728","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1136\/qshc.2003.006585","article-title":"Use of medical emergency team responses to reduce hospital cardiopulmonary arrests.","volume":"13","author":"DeVita","year":"2004","journal-title":"Qual Saf Health Care"},{"key":"R15-20230728","doi-asserted-by":"crossref","first-page":"2091","DOI":"10.1016\/S0140-6736(05)66733-5","article-title":"Introduction of the medical emergency team (MET) system: A cluster-randomised controlled trial.","volume":"365","author":"Hillman","year":"2005","journal-title":"Lancet"},{"key":"R16-20230728","doi-asserted-by":"crossref","first-page":"1210","DOI":"10.1136\/bmj.39385.534236.47","article-title":"Six year audit of cardiac arrests and medical emergency team calls in an Australian outer metropolitan teaching hospital.","volume":"335","author":"Buist","year":"2007","journal-title":"BMJ"},{"key":"R17-20230728","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1186\/s13054-015-0973-y","article-title":"Rapid response systems: A systematic review and meta-analysis.","volume":"19","author":"Maharaj","year":"2015","journal-title":"Crit Care"},{"key":"R18-20230728","doi-asserted-by":"crossref","first-page":"R808","DOI":"10.1186\/cc3906","article-title":"Long term effect of a medical emergency team on cardiac arrests in a teaching hospital.","volume":"9","author":"Jones","year":"2005","journal-title":"Crit Care"},{"key":"R19-20230728","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1002\/jhm.2174","article-title":"Hospital cardiac arrest resuscitation practice in the United States: A nationally representative survey.","volume":"9","author":"Edelson","year":"2014","journal-title":"J Hosp Med"},{"key":"R20-20230728","doi-asserted-by":"crossref","first-page":"e024548","DOI":"10.1136\/bmjopen-2018-024548","article-title":"Characterising variation in composition and activation criteria of rapid response and cardiac arrest teams: A survey of Medicare participating hospitals in five American states.","volume":"9","author":"Mitchell","year":"2019","journal-title":"BMJ Open"},{"key":"R21-20230728","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.jbi.2008.08.010","article-title":"Research electronic data capture (REDCap)\u2013a metadata-driven methodology and workflow process for providing translational research informatics support.","volume":"42","author":"Harris","year":"2009","journal-title":"J Biomed Inform"},{"key":"R22-20230728","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1093\/qjmed\/94.10.521","article-title":"Validation of a modified Early Warning Score in medical admissions.","volume":"94","author":"Subbe","year":"2001","journal-title":"QJM"},{"key":"R23-20230728","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1308\/003588406X130615","article-title":"The value of Modified Early Warning Score (MEWS) in surgical in-patients: A prospective observational study.","volume":"88","author":"Gardner-Thorpe","year":"2006","journal-title":"Ann R Coll Surg Engl"},{"key":"R24-20230728","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/j.resuscitation.2012.12.016","article-title":"The ability of the National Early Warning Score (NEWS) to discriminate patients at risk of early cardiac arrest, unanticipated intensive care unit admission, and death.","volume":"84","author":"Smith","year":"2013","journal-title":"Resuscitation"},{"key":"R25-20230728","doi-asserted-by":"crossref","first-page":"1805","DOI":"10.1097\/CCM.0000000000002648","article-title":"Investigating the impact of different suspicion of infection criteria on the accuracy of quick sepsis-related organ failure assessment, systemic inflammatory response syndrome, and early warning scores.","volume":"45","author":"Churpek","year":"2017","journal-title":"Crit Care Med"},{"key":"R26-20230728","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1097\/CCM.0000000000001571","article-title":"Multicenter comparison of machine learning methods and conventional regression for predicting clinical deterioration on the wards.","volume":"44","author":"Churpek","year":"2016","journal-title":"Crit Care Med"},{"key":"R27-20230728","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.resuscitation.2014.11.014","article-title":"Aggregate National Early Warning Score (NEWS) values are more important than high scores for a single vital signs parameter for discriminating the risk of adverse outcomes.","volume":"87","author":"Jarvis","year":"2015","journal-title":"Resuscitation"},{"key":"R28-20230728","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1097\/CCM.0000000000001346","article-title":"Delayed rapid response team activation is associated with increased hospital mortality, morbidity, and length of stay in a tertiary care institution.","volume":"44","author":"Barwise","year":"2016","journal-title":"Crit Care Med"},{"key":"R29-20230728","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1097\/CCM.0b013e31829e53b9","article-title":"Delayed medical emergency team calls and associated outcomes.","volume":"42","author":"Boniatti","year":"2014","journal-title":"Crit Care Med"},{"key":"R30-20230728","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.jcrc.2018.04.010","article-title":"Factors associated with delayed rapid response team activation.","volume":"46","author":"Reardon","year":"2018","journal-title":"J Crit Care"},{"key":"R31-20230728","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1097\/CCM.0b013e3181928ce3","article-title":"The relationship between early emergency team calls and serious adverse events.","volume":"37","author":"Chen","year":"2009","journal-title":"Crit Care Med"},{"key":"R32-20230728","doi-asserted-by":"crossref","first-page":"2284","DOI":"10.1097\/CCM.0b013e318291cccd","article-title":"The impact of rapid response team on outcome of patients transferred from the ward to the ICU: A single-center study.","volume":"41","author":"Karpman","year":"2013","journal-title":"Crit Care Med"},{"key":"R33-20230728","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.resuscitation.2010.09.480","article-title":"An eight year audit before and after the introduction of modified early warning score (MEWS) charts, of patients admitted to a tertiary referral intensive care unit after CPR.","volume":"82","author":"Moon","year":"2011","journal-title":"Resuscitation"},{"key":"R35-20230728","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1161\/CIR.0b013e31829d8654","article-title":"Cardiopulmonary resuscitation quality: [corrected] improving cardiac resuscitation outcomes both inside and outside the hospital: A consensus statement from the American Heart Association.","volume":"128","author":"Meaney","year":"2013","journal-title":"Circulation"},{"key":"R36-20230728","doi-asserted-by":"crossref","first-page":"S397","DOI":"10.1161\/CIR.0000000000000258","article-title":"Part 4: Systems of care and continuous quality improvement: 2015 American Heart Association guidelines update for cardiopulmonary resuscitation and emergency cardiovascular care.","volume":"132","author":"Kronick","year":"2015","journal-title":"Circulation"},{"key":"R37-20230728","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.resuscitation.2015.07.016","article-title":"European Resuscitation Council Guidelines for resuscitation 2015: Section 3. Adult advanced life support.","volume":"95","author":"Soar","year":"2015","journal-title":"Resuscitation"},{"key":"R38-20230728","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1016\/j.resuscitation.2010.01.024","article-title":"Identifying non-technical skills and barriers for improvement of teamwork in cardiac arrest teams.","volume":"81","author":"Andersen","year":"2010","journal-title":"Resuscitation"},{"key":"R39-20230728","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.resuscitation.2003.08.004","article-title":"Human factors affect the quality of cardiopulmonary resuscitation in simulated cardiac arrests.","volume":"60","author":"Marsch","year":"2004","journal-title":"Resuscitation"},{"key":"R40-20230728","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/1471-227X-9-3","article-title":"Hands-on time during cardiopulmonary resuscitation is affected by the process of teambuilding: A prospective randomised simulator-based trial.","volume":"9","author":"Hunziker","year":"2009","journal-title":"BMC Emerg Med"},{"key":"R41-20230728","doi-asserted-by":"crossref","first-page":"1668","DOI":"10.1097\/01.CCM.0000268059.42429.39","article-title":"Residents feel unprepared and unsupervised as leaders of cardiac arrest teams in teaching hospitals: A survey of internal medicine residents.","volume":"35","author":"Hayes","year":"2007","journal-title":"Crit Care Med"},{"key":"R42-20230728","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1080\/01421590600627821","article-title":"Graduating internal medicine residents\u2019 self-assessment and performance of advanced cardiac life support skills.","volume":"28","author":"Wayne","year":"2006","journal-title":"Med Teach"},{"key":"R43-20230728","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1161\/CIRCULATIONAHA.118.033674","article-title":"How do resuscitation teams at top-performing hospitals for in-hospital cardiac arrest succeed? A qualitative study.","volume":"138","author":"Nallamothu","year":"2018","journal-title":"Circulation"},{"key":"R44-20230728","doi-asserted-by":"crossref","first-page":"S444","DOI":"10.1161\/CIR.0000000000000261","article-title":"Part 7: Adult Advanced Cardiovascular Life Support: 2015 American Heart Association guidelines update for cardiopulmonary resuscitation and emergency cardiovascular care.","volume":"132","author":"Link","year":"2015","journal-title":"Circulation"},{"key":"R45-20230728","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1177\/1751143715591402","article-title":"Mechanical versus manual chest compression for out-of-hospital cardiac arrest (PARAMEDIC): A pragmatic, cluster randomised control trial.","volume":"16","author":"Perkins","year":"2015","journal-title":"J Intensive Care Soc"},{"key":"R46-20230728","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.resuscitation.2015.01.026","article-title":"Quantitative relationship between end-tidal carbon dioxide and CPR quality during both in-hospital and out-of-hospital cardiac arrest.","volume":"89","author":"Sheak","year":"2015","journal-title":"Resuscitation"},{"key":"R47-20230728","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/j.annemergmed.2011.07.020","article-title":"Intraosseous versus intravenous vascular access during out-of-hospital cardiac arrest: A randomized controlled trial.","volume":"58","author":"Reades","year":"2011","journal-title":"Ann Emerg Med"},{"key":"R48-20230728","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1097\/CCM.0b013e318287f2c4","article-title":"Use of therapeutic hypothermia after in-hospital cardiac arrest.","volume":"41","author":"Mikkelsen","year":"2013","journal-title":"Crit Care Med"},{"key":"R49-20230728","doi-asserted-by":"crossref","first-page":"S465","DOI":"10.1161\/CIR.0000000000000262","article-title":"Part 8: Post-cardiac arrest care: 2015 American Heart Association guidelines update for cardiopulmonary resuscitation and emergency cardiovascular care.","volume":"132","author":"Callaway","year":"2015","journal-title":"Circulation"},{"key":"R50-20230728","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1097\/MAT.0000000000000475","article-title":"Extracorporeal life support organization registry international report 2016.","volume":"63","author":"Thiagarajan","year":"2017","journal-title":"ASAIO J"},{"key":"R51-20230728","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1016\/j.resuscitation.2013.01.022","article-title":"A review of rapid response team activation parameters in New Zealand hospitals.","volume":"84","author":"Psirides","year":"2013","journal-title":"Resuscitation"},{"key":"R52-20230728","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1111\/aas.12280","article-title":"Cardiac arrest teams and medical emergency teams in Finland: A nationwide cross-sectional postal survey.","volume":"58","author":"Tirkkonen","year":"2014","journal-title":"Acta Anaesthesiol Scand"},{"key":"R53-20230728","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.resuscitation.2015.01.014","article-title":"Organisation of in-hospital cardiac arrest teams - a nationwide study.","volume":"89","author":"Lauridsen","year":"2015","journal-title":"Resuscitation"}],"container-title":["Critical Care Explorations"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/02107256-201908000-00006","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,28]],"date-time":"2023-07-28T04:15:10Z","timestamp":1690517710000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/02107256-201908000-00006"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8]]},"references-count":50,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2019]]}},"URL":"https:\/\/doi.org\/10.1097\/cce.0000000000000031","relation":{},"ISSN":["2639-8028"],"issn-type":[{"value":"2639-8028","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,8]]}}}