{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T02:29:10Z","timestamp":1791253750911,"version":"4.1.0"},"reference-count":60,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Critical Care Medicine"],"published-print":{"date-parts":[[2009,8]]},"DOI":"10.1097\/ccm.0b013e3181a557a2","type":"journal-article","created":{"date-parts":[[2010,2,25]],"date-time":"2010-02-25T01:20:10Z","timestamp":1267060810000},"page":"2421-2426","source":"Crossref","is-referenced-by-count":69,"title":["Orexigenic hormone ghrelin ameliorates gut barrier dysfunction in sepsis in rats*"],"prefix":"10.1097","volume":"37","author":[{"given":"Rongqian","family":"Wu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weifeng","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoling","family":"Qiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haichao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven A.","family":"Blau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thanjavur S.","family":"Ravikumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-13-20160304","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1097\/00003246-200107000-00002","volume":"29","author":"Angus","year":"2001","journal-title":"Crit Care Med"},{"key":"R2-13-20160304","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1097\/CCM.0B013E318165B886","volume":"36","author":"Carlet","year":"2008","journal-title":"Crit Care Med"},{"key":"R3-13-20160304","first-page":"256","volume":"9","author":"Fink","year":"1994","journal-title":"Semin Respir Infect"},{"key":"R4-13-20160304","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1164\/ajrccm.158.2.9710092","volume":"158","author":"Doig","year":"1998","journal-title":"Am J Respir Crit Care Med"},{"key":"R5-13-20160304","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1097\/01.bcr.0000176878.79267.e8","volume":"26","author":"Magnotti","year":"2005","journal-title":"J Burn Care Rehabil"},{"key":"R6-13-20160304","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1007\/s002689900065","volume":"20","author":"Swank","year":"1996","journal-title":"World J Surg"},{"key":"R7-13-20160304","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1038\/45230","volume":"402","author":"Kojima","year":"1999","journal-title":"Nature"},{"key":"R8-13-20160304","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1152\/physrev.00012.2004","volume":"85","author":"Kojima","year":"2005","journal-title":"Physiol Rev"},{"key":"R9-13-20160304","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/S0167-0115(02)00012-5","volume":"105","author":"Wang","year":"2002","journal-title":"Regul Pept"},{"key":"R10-13-20160304","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1097\/01.sla.0000251614.42290.ed","volume":"245","author":"Wu","year":"2007","journal-title":"Ann Surg"},{"key":"R11-13-20160304","doi-asserted-by":"crossref","first-page":"H1296","DOI":"10.1152\/ajpheart.00852.2003","volume":"287","author":"Wu","year":"2004","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"R12-13-20160304","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.cardiores.2005.06.011","volume":"68","author":"Wu","year":"2005","journal-title":"Cardiovasc Res"},{"key":"R13-13-20160304","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1164\/rccm.200604-511OC","volume":"176","author":"Wu","year":"2007","journal-title":"Am J Respir Crit Care Med"},{"key":"R14-13-20160304","doi-asserted-by":"crossref","first-page":"E1697","DOI":"10.1152\/ajpendo.00098.2007","volume":"293","author":"Wu","year":"2007","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"R15-13-20160304","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1126\/science.285.5425.248","volume":"285","author":"Wang","year":"1999","journal-title":"Science"},{"key":"R16-13-20160304","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1084\/jem.192.4.565","volume":"192","author":"Andersson","year":"2000","journal-title":"J Exp Med"},{"key":"R17-13-20160304","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1097\/01.CCM.0000155991.88802.4D","volume":"33","author":"Sunden-Cullberg","year":"2005","journal-title":"Crit Care Med"},{"key":"R18-13-20160304","doi-asserted-by":"crossref","first-page":"2652","DOI":"10.1182\/blood-2002-05-1300","volume":"101","author":"Fiuza","year":"2003","journal-title":"Blood"},{"key":"R19-13-20160304","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1073\/pnas.2434651100","volume":"101","author":"Yang","year":"2004","journal-title":"Proc Natl Acad Sci U S A"},{"key":"R20-13-20160304","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1038\/nm1124","volume":"10","author":"Wang","year":"2004","journal-title":"Nat Med"},{"key":"R21-13-20160304","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1053\/gast.2002.35391","volume":"123","author":"Sappington","year":"2002","journal-title":"Gastroenterology"},{"key":"R22-13-20160304","doi-asserted-by":"crossref","first-page":"105","DOI":"10.2119\/2006-00010.Yang","volume":"12","author":"Yang","year":"2006","journal-title":"Mol Med"},{"key":"R23-13-20160304","doi-asserted-by":"crossref","first-page":"2246","DOI":"10.1097\/00003246-199910000-00030","volume":"27","author":"Chavez","year":"1999","journal-title":"Crit Care Med"},{"key":"R24-13-20160304","doi-asserted-by":"crossref","first-page":"G621","DOI":"10.1152\/ajpgi.00177.2003","volume":"285","author":"Yang","year":"2003","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"R25-13-20160304","doi-asserted-by":"crossref","first-page":"e2026","DOI":"10.1371\/journal.pone.0002026","volume":"3","author":"Wu","year":"2008","journal-title":"PLoS ONE"},{"key":"R26-13-20160304","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1084\/jem.20011714","volume":"195","author":"Bernik","year":"2002","journal-title":"J Exp Med"},{"key":"R27-13-20160304","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1038\/35013070","volume":"405","author":"Borovikova","year":"2000","journal-title":"Nature"},{"key":"R28-13-20160304","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1172\/JCI30587","volume":"117","author":"Strober","year":"2007","journal-title":"J Clin Invest"},{"key":"R29-13-20160304","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1097\/SHK.0b013e318160f47f","volume":"30","author":"Zayat","year":"2008","journal-title":"Shock"},{"key":"R30-13-20160304","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1097\/01.BCR.0000150212.21651.79","volume":"26","author":"Gosain","year":"2005","journal-title":"J Burn Care Rehabil"},{"key":"R31-13-20160304","doi-asserted-by":"crossref","first-page":"2604","DOI":"10.1210\/en.2004-0346","volume":"145","author":"Cowley","year":"2004","journal-title":"Endocrinology"},{"key":"R32-13-20160304","doi-asserted-by":"crossref","first-page":"4284","DOI":"10.1210\/jcem.86.9.7866","volume":"86","author":"Hattori","year":"2001","journal-title":"J Clin Endocrinol Metab"},{"key":"R33-13-20160304","first-page":"3803","volume":"85","author":"Papotti","year":"2000","journal-title":"J Clin Endocrinol Metab"},{"key":"R34-13-20160304","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1016\/S0024-3205(00)01001-8","volume":"68","author":"Shuto","year":"2001","journal-title":"Life Sci"},{"key":"R35-13-20160304","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/S0304-3940(03)00294-5","volume":"342","author":"Sakata","year":"2003","journal-title":"Neurosci Lett"},{"key":"R36-13-20160304","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/S0083-6729(06)77014-5","volume":"77","author":"Taub","year":"2008","journal-title":"Vitam Horm"},{"key":"R37-13-20160304","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1172\/JCI200421134","volume":"114","author":"Dixit","year":"2004","journal-title":"J Clin Invest"},{"key":"R38-13-20160304","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1053\/gast.1997.v113.pm9322519","volume":"113","author":"Unno","year":"1997","journal-title":"Gastroenterology"},{"key":"R39-13-20160304","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1172\/JCI114164","volume":"84","author":"Deitch","year":"1989","journal-title":"J Clin Invest"},{"key":"R40-13-20160304","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/S0016-5085(97)70226-9","volume":"112","author":"De","year":"1997","journal-title":"Gastroenterology"},{"key":"R41-13-20160304","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1126\/science.2922595","volume":"243","author":"Bianchi","year":"1989","journal-title":"Science"},{"key":"R42-13-20160304","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1093\/embo-reports\/kvd030","volume":"1","author":"Bianchi","year":"2000","journal-title":"EMBO Rep"},{"key":"R43-13-20160304","doi-asserted-by":"crossref","first-page":"3890","DOI":"10.4049\/jimmunol.170.7.3890","volume":"170","author":"Rendon-Mitchell","year":"2003","journal-title":"J Immunol"},{"key":"R44-13-20160304","doi-asserted-by":"crossref","first-page":"C990","DOI":"10.1152\/ajpcell.00308.2005","volume":"290","author":"Liu","year":"2006","journal-title":"Am J Physiol Cell Physiol"},{"key":"R45-13-20160304","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1038\/nature00858","volume":"418","author":"Scaffidi","year":"2002","journal-title":"Nature"},{"key":"R46-13-20160304","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/BF03402105","volume":"9","author":"Li","year":"2003","journal-title":"Mol Med"},{"key":"R47-13-20160304","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1038\/nature01339","volume":"421","author":"Wang","year":"2003","journal-title":"Nature"},{"key":"R48-13-20160304","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1038\/nature01321","volume":"420","author":"Tracey","year":"2002","journal-title":"Nature"},{"key":"R49-13-20160304","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/S1566-0702(00)00233-2","volume":"85","author":"Borovikova","year":"2000","journal-title":"Auton Neurosci"},{"key":"R50-13-20160304","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1053\/gast.2002.35954","volume":"123","author":"Date","year":"2002","journal-title":"Gastroenterology"},{"key":"R51-13-20160304","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1124\/jpet.102.034827","volume":"302","author":"Banks","year":"2002","journal-title":"J Pharmacol Exp Ther"},{"key":"R52-13-20160304","first-page":"777","volume":"12","author":"Wu","year":"2003","journal-title":"Int J Mol Med"},{"key":"R53-13-20160304","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1038\/nn1656","volume":"9","author":"Diano","year":"2006","journal-title":"Nat Neurosci"},{"key":"R54-13-20160304","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1016\/S0896-6273(03)00063-1","volume":"37","author":"Cowley","year":"2003","journal-title":"Neuron"},{"key":"R55-13-20160304","doi-asserted-by":"crossref","first-page":"8369","DOI":"10.4049\/jimmunol.180.12.8369","volume":"180","author":"Chorny","year":"2008","journal-title":"J Immunol"},{"key":"R56-13-20160304","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1097\/00024382-200202000-00010","volume":"17","author":"Xu","year":"2002","journal-title":"Shock"},{"key":"R57-13-20160304","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1016\/S1091-255X(01)00016-6","volume":"6","author":"Deitch","year":"2002","journal-title":"J Gastrointest Surg"},{"key":"R58-13-20160304","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1097\/01.shk.0000112346.38599.10","volume":"21","author":"Han","year":"2004","journal-title":"Shock"},{"key":"R59-13-20160304","doi-asserted-by":"crossref","first-page":"1791","DOI":"10.1111\/j.1440-1746.2006.04696.x","volume":"22","author":"El Eter","year":"2007","journal-title":"J Gastroenterol Hepatol"},{"key":"R60-13-20160304","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1038\/bjp.2008.120","volume":"154","author":"Sibilia","year":"2008","journal-title":"Br J Pharmacol"}],"container-title":["Critical Care Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00003246-200908000-00013","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T18:17:47Z","timestamp":1786040267000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00003246-200908000-00013"}},"subtitle":[""],"short-title":[],"issued":{"date-parts":[[2009,8]]},"references-count":60,"journal-issue":{"issue":"8"},"URL":"https:\/\/doi.org\/10.1097\/ccm.0b013e3181a557a2","relation":{},"ISSN":["0090-3493"],"issn-type":[{"value":"0090-3493","type":"print"}],"subject":[],"published":{"date-parts":[[2009,8]]}}}