{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T00:29:41Z","timestamp":1773102581705,"version":"3.50.1"},"reference-count":26,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:sec>\n            <jats:title>Background:<\/jats:title>\n            <jats:p>Few studies have examined the prevalence of cancer worry in the general and at-risk population. The objective of this study was to describe the prevalence of cancer worry in a sample of individuals at increased risk of developing hereditary cancer, determine differences in cancer worry by socio-demographic characteristics and assess the relationship between cancer worry and psychological distress.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>A cross-sectional study was designed with 895 patients. The Cancer Worry Scale (CWS), Hospital Anxiety and Depression Scale (HADS) for psychological distress and sociodemographic characteristics were examined. The multiple linear regression model was developed to explore what variables were predicted for cancer worry. To identify variables associated with higher cancer worry scores, a logistic model was fitted.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>In the at-higher-risk sample of hereditary cancer, the mean of CWS was 10.20 (SD: 3.70). The significant predictors for cancer worry were gender, age, previous psychiatric treatment, patients affected by cancer and having children. In the sample, 38% of patients had higher scores on cancer worry, the variables associated were patients affected by cancer compared, women, widow\/divorced participants, less than secondary school, patients with previous psychiatric treatment and patients less than 55\u2009years old. Using the HADS cutoff score 29% of the sample showed significant psychological distress, more anxiety (35%) than depressive (22%) symptomatology. Psychological distress showed a higher variability (36%) on cancer worry.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>Findings highlighted distinctive profiles in socio-demographic characteristics according to the degree of cancer worry; therefore, genetic counseling should continue to be provided to address cancer worry and relieve psychological distress.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/cej.0000000000000862","type":"journal-article","created":{"date-parts":[[2023,11,24]],"date-time":"2023-11-24T13:00:58Z","timestamp":1700830858000},"page":"293-298","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Cancer worry at higher-risk sample of hereditary cancer in Spain"],"prefix":"10.1097","volume":"33","author":[{"given":"Gema","family":"Costa-Requena","sequence":"first","affiliation":[{"name":"Department of Psychiatry and Clinical Psychology, Hospital Universitari i Polit\u00e8cnic La Fe"},{"name":"Genetic Counselling Unit for Hereditary Cancer, Department of Oncology, Hospital Universitari i Polit\u00e8cnic La Fe, Valencia, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paula","family":"Richart-Aznar","sequence":"additional","affiliation":[{"name":"Genetic Counselling Unit for Hereditary Cancer, Department of Oncology, Hospital Universitari i Polit\u00e8cnic La Fe, Valencia, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c1ngel","family":"Segura-Huerta","sequence":"additional","affiliation":[{"name":"Genetic Counselling Unit for Hereditary Cancer, Department of Oncology, Hospital Universitari i Polit\u00e8cnic La Fe, Valencia, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","published-online":{"date-parts":[[2023,11,13]]},"reference":[{"key":"R1-20250527","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1007\/s13187-017-1195-6","article-title":"Influence of cancer worry on four cancer related health protective behaviors among a nationally representative sample: implications for health promotion efforts.","volume":"33","author":"Amuta","year":"2017","journal-title":"J Cancer Educ"},{"key":"R2-20250527","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1023\/A:1012272031953","article-title":"Adherence to recommendations for clinical follow-up after benign breast biopsy.","volume":"69","author":"Andrykowski","year":"2001","journal-title":"Breast Cancer Res Treat"},{"key":"R3-20250527","article-title":"The evolution of worry after breast cancer risk assessment: 6-year follow-up of the TRACE study cohort.","volume":"2","author":"Brain","year":"2011","journal-title":"Psycho-Oncol"},{"key":"R4-20250527","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1016\/j.pec.2009.10.032","article-title":"The impact of genetic counseling on knowledge and emotional responses in Spanish population with family history of breast cancer.","volume":"78","author":"Cabrera","year":"2010","journal-title":"Patient Educ Couns"},{"key":"R5-20250527","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.medcli.2010.04.015","article-title":"Versi\u00f3n espa\u00f1ola de la Cancer Worry Scale (Escala de Preocupaci\u00f3n por el C\u00e1ncer: adaptaci\u00f3n cultural y an\u00e1lisis de la validez y fiabilidad).","volume":"136","author":"Cabrera","year":"2011","journal-title":"Med Clin (Barc)"},{"key":"R6-20250527","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1186\/s13053-022-00229-x","article-title":"Psychological and health behaviour outcomes following multi-gene panel testing for hereditary breast and ovarian cancer risk: a mini-review of the literature.","volume":"20","author":"Carlsson","year":"2022","journal-title":"Hered Cancer Clin Pract"},{"key":"R7-20250527","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1038\/bjc.1994.423","article-title":"The impact of genetic counselling on risk perception in women with a family history of breast cancer.","volume":"70","author":"Evans","year":"1994","journal-title":"Br J Cancer"},{"key":"R8-20250527","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1002\/pon.864","article-title":"The role of cancer worry in cancer screening: a theoretical and empirical review of the literature.","volume":"14","author":"Hay","year":"2005","journal-title":"Psychooncology"},{"key":"R9-20250527","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.ypmed.2006.03.002","article-title":"Does worry about breast cancer predict screening behaviors? 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