{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T19:46:34Z","timestamp":1789847194522,"version":"4.0.1"},"reference-count":23,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The aim of the present study was to evaluate the factors associated with a higher or lower likelihood of being early diagnosed with melanoma at stage I in Germany.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective cross-sectional study utilizes data from the German skin cancer registry (Arbeitsgemeinschaft Dermatologische Onkologie Registry) and included 12 648 patients with a first melanoma diagnosis in 80 hospitals between 1 January 2018 and 30 November 2024. Multivariable logistic regression analyses were conducted to assess the associations between demographic and clinical variables and the likelihood of being early diagnosed with stage I melanoma.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>This study included 4138 patients with stage I and 8510 patients with stages II\u2013IV melanoma. Factors including older age [adjusted odds ratio (aOR): 0.61] for age group 71\u201380 years and 0.54 for age group\u2005&gt;\u200580 years, compared to the age group 18\u201340 year, male sex (aOR: 0.73), Celtic (aOR: 0.66), mixed (aOR: 0.58), and Mediterranean (aOR: 0.31) skin types, melanomas located on the gluteal region (aOR: 0.35), scalp and neck (aOR: 0.44), lower limb (aOR: 0.51), upper limb (aOR: 0.67), and back (aOR: 0.72) and being single (aOR: 0.81) were negatively associated with an early diagnosis of stage I melanoma. Finally, a positive association was observed between a family history of skin cancer and the likelihood of being diagnosed with stage I melanoma (aOR: 1.50).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study provides important insights into the demographic and clinical factors associated with early-stage melanoma diagnosis in Germany and underscores the importance of targeted interventions aimed at increasing melanoma awareness.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1097\/cej.0000000000000970","type":"journal-article","created":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T10:02:08Z","timestamp":1745575328000},"page":"166-172","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Factors associated with the likelihood of being diagnosed with stage I melanoma in Germany: a multicenter study on 12 648 patients from the ADOReg skin cancer registry"],"prefix":"10.1097","volume":"35","author":[{"given":"Karel","family":"Kostev","sequence":"first","affiliation":[{"name":"Epidemiology, IQVIA, Frankfurt, Germany"},{"name":"University Clinic, Philipps-University, Marburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ira","family":"Rodemer","sequence":"additional","affiliation":[{"name":"Epidemiology, IQVIA, Frankfurt, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Svetlana","family":"Alymova","sequence":"additional","affiliation":[{"name":"Epidemiology, IQVIA, Frankfurt, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcel","family":"Konrad","sequence":"additional","affiliation":[{"name":"Department of Health and Social Studies, FOM University of Applied Sciences for Economics and Management, Frankfurt, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,4,18]]},"reference":[{"issue":"1 Suppl","key":"R1-20260130","doi-asserted-by":"crossref","first-page":"S49","DOI":"10.1016\/j.ijwd.2017.02.009","article-title":"Skin cancer concerns particular to women.","volume":"3","author":"Al-Dujaili","year":"2017","journal-title":"Int J Womens Dermatol"},{"key":"R2-20260130","doi-asserted-by":"crossref","first-page":"3857","DOI":"10.1007\/s10792-022-02406-2","article-title":"Uveal melanoma and marital status: a relationship that affects survival.","volume":"42","author":"Alfaar","year":"2022","journal-title":"Int Ophthalmol"},{"key":"R3-20260130","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1001\/jamadermatol.2022.0160","article-title":"Global burden of cutaneous melanoma in 2020 and projections to 2040.","volume":"158","author":"Arnold","year":"2022","journal-title":"JAMA Dermatol"},{"key":"R4-20260130","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1097\/DSS.0000000000000292","article-title":"Family history of skin cancer is associated with increased risk of cutaneous squamous cell carcinoma.","volume":"41","author":"Asgari","year":"2015","journal-title":"Dermatol Surg"},{"key":"R5-20260130","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1007\/s13670-020-00330-w","article-title":"Melanoma diagnosis and treatment in the elderly.","volume":"9","author":"Babbush","year":"2020","journal-title":"Curr Geri Rep"},{"key":"R6-20260130","doi-asserted-by":"crossref","first-page":"85","DOI":"10.2217\/mmt-2016-0001","article-title":"Does an increased number of moles correlate to a higher risk of melanoma?","volume":"3","author":"Bhatt","year":"2016","journal-title":"Melanoma Manag"},{"key":"R7-20260130","doi-asserted-by":"crossref","first-page":"737399","DOI":"10.3389\/fonc.2021.737399","article-title":"Prognosis for cutaneous melanoma by clinical and pathological profile: a population-based study.","volume":"11","author":"Buja","year":"2021","journal-title":"Front Oncol"},{"key":"R8-20260130","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1016\/j.jaad.2011.05.021","article-title":"Skin cancer risk perceptions: a comparison across ethnicity, age, education, gender, and income.","volume":"66","author":"Buster","year":"2012","journal-title":"J Am Acad Dermatol"},{"key":"R9-20260130","doi-asserted-by":"crossref","first-page":"1150","DOI":"10.1001\/jamadermatol.2013.706","article-title":"Distinctive features of melanoma and its management in elderly patients: a population-based study in France.","volume":"149","author":"Ciocan","year":"2013","journal-title":"JAMA Dermatol"},{"key":"R10-20260130","article-title":"S3 - Leitlinie zur Diagnostik, Therapie und Nachsorge des Melanoms.","volume":"18. 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