{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:11:23Z","timestamp":1786119083215,"version":"build-2736575974"},"reference-count":19,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2009,4]]},"DOI":"10.1097\/cej.0b013e3283101292","type":"journal-article","created":{"date-parts":[[2009,1,28]],"date-time":"2009-01-28T03:25:03Z","timestamp":1233113103000},"page":"117-119","source":"Crossref","is-referenced-by-count":39,"title":["CD14-159C\/T and TLR9-1237T\/C polymorphisms are not associated with gastric cancer risk in Caucasian populations"],"prefix":"10.1097","volume":"18","author":[{"given":"Georgina L.","family":"Hold","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles S.","family":"Rabkin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marilie D.","family":"Gammon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan H.","family":"Berry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malcolm G.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jolanta","family":"Lissowska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harvey A.","family":"Risch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wong-Ho","family":"Chow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N. Ashley G.","family":"Mowat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas L.","family":"Vaughan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emad M.","family":"El-Omar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-4-20210128","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S0165-2478(02)00010-X","article-title":"Up-regulation of TLR9 gene expression by LPS in mouse macrophages via activation of NF-kappaB, ERK and p38 MAPK signal pathways","volume":"81","author":"An","year":"2002","journal-title":"Immunol Lett"},{"key":"R2-4-20210128","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1038\/sj.gene.6364111","article-title":"NOD2\/CARD15, TLR4 and CD14 mutations in Scottish and Irish Crohn's disease patients: evidence for genetic heterogeneity within Europe?","volume":"5","author":"Arnott","year":"2004","journal-title":"Genes Immun"},{"key":"R3-4-20210128","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1165\/ajrcmb.20.5.3494","article-title":"A Polymorphism* in the 5' flanking region of the CD14 gene is associated with circulating soluble CD14 levels and with total serum immunoglobulin E","volume":"5","author":"Baldini","year":"1999","journal-title":"Am J Respir Cell Mol Biol"},{"key":"R4-4-20210128","doi-asserted-by":"crossref","first-page":"9237","DOI":"10.1073\/pnas.161293498","article-title":"Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition","volume":"98","author":"Bauer","year":"2001","journal-title":"Proc Natl Acad Sci U S A"},{"key":"R5-4-20210128","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1097\/CEJ.0b013e32809b4d0f","article-title":"The interleukin-8-251*T\/*A polymorphism is not associated with risk for gastric carcinoma development in a Portuguese population","volume":"17","author":"Canedo","year":"2008","journal-title":"Eur J Cancer Prev"},{"key":"R6-4-20210128","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1002\/(SICI)1097-0215(19990611)81:6<871::AID-IJC6>3.0.CO;2-#","article-title":"Risk of stomach cancer in relation to consumption of cigarettes, alcohol, tea and coffee In Warsaw, Poland","volume":"81","author":"Chow","year":"1999","journal-title":"Int J Cancer"},{"key":"R7-4-20210128","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1038\/35006081","article-title":"Interleukin-1 polymorphisms associated with increased risk of gastric cancer","volume":"404","author":"El Omar","year":"2000","journal-title":"Nature"},{"key":"R8-4-20210128","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1093\/jnci\/89.17.1277","article-title":"Tobacco, alcohol, and socioeconomic status and adenocarcinomas of the esophagus and gastric cardia","volume":"89","author":"Gammon","year":"1997","journal-title":"J Natl Cancer Inst"},{"key":"R9-4-20210128","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1038\/35047123","article-title":"A Toll-like receptor recognizes bacterial DNA","volume":"408","author":"Hemmi","year":"2000","journal-title":"Nature"},{"key":"R10-4-20210128","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/S0016-5085(03)80097-5","article-title":"A functional Toll-like receptor 4 polymorphism increases the risk of H. pylori-induced pre-malignant changes in the stomach","volume":"124","author":"Hold","year":"2003","journal-title":"Gastroenterology"},{"key":"R11-4-20210128","first-page":"A61","article-title":"Innate immune response gene polymorphisms and their role in H-pylori-induced gastric cancer","volume":"130","author":"Hold","year":"2006","journal-title":"Gastroenterology"},{"key":"R12-4-20210128","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1053\/j.gastro.2006.12.026","article-title":"A functional polymorphism of toll-like receptor 4 gene increases risk of gastric carcinoma and its precursors","volume":"132","author":"Hold","year":"2007","journal-title":"Gastroenterology"},{"key":"R13-4-20210128","doi-asserted-by":"crossref","first-page":"3218","DOI":"10.1161\/01.CIR.99.25.3218","article-title":"C(\u2013260)\u2013>T polymorphism in the promoter of the CD14 monocyte receptor gene as a risk factor for myocardial infarction","volume":"99","author":"Hubacek","year":"1999","journal-title":"Circulation"},{"key":"R14-4-20210128","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1007\/s10620-006-9303-1","article-title":"Polymorphisms in genes related to bacterial lipopolysaccharide\/peptidoglycan signaling and gastric precancerous lesions in a population at high risk for gastric cancer","volume":"52","author":"Kato","year":"2007","journal-title":"Dig Dis Sci"},{"key":"R15-4-20210128","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1164\/ajrccm.163.4.2004164","article-title":"Association of a promoter polymorphism of the CD14 gene and atopy","volume":"163","author":"Koppelman","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"key":"R16-4-20210128","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1158\/1055-9965.EPI-05-0887","article-title":"Interleukin-8 Polymorphisms Are Not Associated with Gastric Cancer Risk in a Polish Population","volume":"15","author":"Savage","year":"2006","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"R17-4-20210128","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1111\/j.1365-2249.2004.02464.x","article-title":"Expression and subcellular distribution of toll-like receptors TLR4, TLR5 and TLR9 on the gastric epithelium in Helicobacter pylori infection","volume":"136","author":"Schmausser","year":"2004","journal-title":"Clin Exp Immunol"},{"key":"R18-4-20210128","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.clim.2004.03.002","article-title":"Polymorphisms of the lipopolysaccharide-signaling complex in inflammatory bowel disease: association of a mutation in the Toll-like receptor 4 gene with ulcerative colitis","volume":"112","author":"Torok","year":"2004","journal-title":"Clin Immunol"},{"key":"R19-4-20210128","first-page":"807","article-title":"Functional polymorphisms of CD14 and toll-like receptor 4 in Taiwanese Chinese with Helicobacter pylori-related gastric malignancies","volume":"53","author":"Wu","year":"2006","journal-title":"Hepato-Gastroenterology"}],"container-title":["European Journal of Cancer Prevention"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00008469-200904000-00004","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T17:32:47Z","timestamp":1786037567000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00008469-200904000-00004"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,4]]},"references-count":19,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2009]]}},"URL":"https:\/\/doi.org\/10.1097\/cej.0b013e3283101292","relation":{},"ISSN":["0959-8278"],"issn-type":[{"value":"0959-8278","type":"print"}],"subject":[],"published":{"date-parts":[[2009,4]]}}}