{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T14:18:18Z","timestamp":1785161898392,"version":"3.55.0"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,4]]},"DOI":"10.1097\/cmr.0b013e32835e589c","type":"journal-article","created":{"date-parts":[[2013,1,25]],"date-time":"2013-01-25T11:52:51Z","timestamp":1359114771000},"page":"175-178","source":"Crossref","is-referenced-by-count":50,"title":["Long-term stabilization of leptomeningeal disease with whole-brain radiation therapy in a patient with metastatic melanoma treated with vemurafenib"],"prefix":"10.1097","volume":"23","author":[{"given":"Jee Min","family":"Lee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Urvi N.","family":"Mehta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ly H.","family":"Dsouza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beverly Ashleigh","family":"Guadagnolo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deborah L.","family":"Sanders","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin B.","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-12-20210129","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1023\/B:NEON.0000021785.00660.2b","article-title":"Posterior fossa metastases: risk of leptomeningeal disease when treated with stereotactic radiosurgery compared to surgery.","volume":"67","author":"Siomin","year":"2004","journal-title":"J Neurooncol"},{"key":"R2-12-20210129","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1007\/s10585-009-9298-z","article-title":"Leptomeningeal metastases from prostate cancer: an emerging clinical conundrum.","volume":"27","author":"Orphanos","year":"2010","journal-title":"Clin Exp Metastasis"},{"key":"R3-12-20210129","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1215\/15228517-2008-062","article-title":"Prognostic factors and outcomes in patients with leptomeningeal melanomatosis.","volume":"10","author":"Harstad","year":"2008","journal-title":"Neuro Oncol"},{"key":"R4-12-20210129","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1007\/s11940-012-0182-9","article-title":"Leptomeningal metastases.","volume":"14","author":"Bruna","year":"2012","journal-title":"Curr Treat Options Neurol"},{"key":"R5-12-20210129","doi-asserted-by":"crossref","first-page":"1687","DOI":"10.1002\/cncr.25634","article-title":"Prognostic factors for survival in melanoma patients with brain metastases.","volume":"117","author":"Davies","year":"2011","journal-title":"Cancer"},{"key":"R6-12-20210129","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1188\/09.CJON.384-387","article-title":"Diagnosis and management of leptomeningeal disease.","volume":"13","author":"Walker","year":"2009","journal-title":"Clin J Oncol Nurs"},{"key":"R7-12-20210129","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1016\/j.radonc.2010.12.017","article-title":"Melanoma cells show a heterogeneous range of sensitivity to ionizing radiation and are radiosensitized by inhibition of B-RAF with PLX-4032.","volume":"98","author":"Sambade","year":"2011","journal-title":"Radiother Oncol"},{"key":"R9-12-20210129","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1007\/0-387-24199-X_9","article-title":"Radiation therapy for leptomeningeal cancer.","volume":"125","author":"Mehta","year":"2005","journal-title":"Cancer Treat Res"},{"key":"R10-12-20210129","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1124\/jpet.112.192195","article-title":"Impact of P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) on the brain distribution of a novel BRAF inhibitor: vemurafenib (PLX4032).","volume":"342","author":"Mittapalli","year":"2012","journal-title":"J Pharmacol Exp Ther"},{"key":"R11-12-20210129","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1016\/j.ijrobp.2010.12.071","article-title":"The evolving role of radiation therapy in the management of malignant melanoma.","volume":"80","author":"Khan","year":"2011","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"R12-12-20210129","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1186\/1479-5876-10-85","article-title":"The role of BRAF V600 mutation in melanoma.","volume":"10","author":"Ascierto","year":"2012","journal-title":"J Transl Med"}],"container-title":["Melanoma Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/CMR.0b013e32835e589c","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,24]],"date-time":"2021-05-24T20:24:14Z","timestamp":1621887854000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00008390-201304000-00012"}},"subtitle":["a case report"],"short-title":[],"issued":{"date-parts":[[2013,4]]},"references-count":11,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013]]}},"URL":"https:\/\/doi.org\/10.1097\/cmr.0b013e32835e589c","relation":{},"ISSN":["0960-8931"],"issn-type":[{"value":"0960-8931","type":"print"}],"subject":[],"published":{"date-parts":[[2013,4]]}}}