{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:16:08Z","timestamp":1786119368680,"version":"build-2736575974"},"reference-count":16,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2009,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title\/>\n                    <jats:p>We present a case of Ehlers-Danlos Syndrome (EDS) type IV with associated neuromuscular manifestations. The patient presented with nonspecific myopathic-type symptoms and later developed a spontaneous median mononeuropathy in the forearm. We believe that the case presented here complements current published neuromuscular manifestations occurring in EDS IV patients and illustrates the urgency of making the diagnosis, given the increased mortality associated with EDS IV.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1097\/cnd.0b013e3181bab6e3","type":"journal-article","created":{"date-parts":[[2009,11,27]],"date-time":"2009-11-27T19:23:44Z","timestamp":1259349824000},"page":"81-87","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Neuromuscular Manifestations in a Patient with Ehlers-Danlos Syndrome Type IV"],"prefix":"10.1097","volume":"11","author":[{"given":"Alexandru","family":"Barboi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cedric","family":"Dennis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Timins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wendy","family":"Peltier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Craig M","family":"Klotz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Safwan","family":"Jaradeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-5-20240808","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1056\/NEJM200003093421001","article-title":"Clinical and genetic features of Ehlers-Danlos syndrome type IV, the vascular type.","volume":"342","author":"Pepin","year":"2000","journal-title":"N Engl J Med"},{"key":"R2-5-20240808","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1002\/(SICI)1096-8628(19980428)77:1<31::AID-AJMG8>3.0.CO;2-O","article-title":"Ehlers-Danlos syndromes: revised nosology, Villefranche, 1997. Ehlers-Danlos National Foundation (USA) and Ehlers-Danlos Support Group (UK).","volume":"77","author":"Beighton","year":"1998","journal-title":"Am J Med Genet"},{"key":"R3-5-20240808","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1007\/s10016-001-0229-y","article-title":"Clinical and genetic features of vascular Ehlers-Danlos syndrome.","volume":"16","author":"Germain","year":"2002","journal-title":"Ann Vasc Surg"},{"key":"R4-5-20240808","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.jvs.2005.03.053","article-title":"The spectrum, management and clinical outcome of Ehlers-Danlos syndrome type IV: a 30-year experience.","volume":"42","author":"Oderich","year":"2005","journal-title":"J Vasc Surg"},{"key":"R5-5-20240808","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1136\/ard.48.11.953","article-title":"Ehlers-Danlos syndrome, clotting disorders and muscular dystrophy.","volume":"48","author":"Bertin","year":"1989","journal-title":"Ann Rheum Dis"},{"key":"R6-5-20240808","first-page":"444","article-title":"Muscle formation in Ehlers-Danlos syndrome.","volume":"62","author":"Bilkey","year":"1981","journal-title":"Arch Phys Med Rehabil"},{"key":"R7-5-20240808","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1034\/j.1399-0004.2003.00075.x","article-title":"Neurological presentation of Ehlers-Danlos syndrome type IV in a family with parental mosaicism.","volume":"63","author":"Palmeri","year":"2003","journal-title":"Clin Genet"},{"key":"R8-5-20240808","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1055\/s-2008-1071447","article-title":"Type III collagen deficient EDS IV producing muscular hypotonia with abnormal muscle fibroblasts.","volume":"22","author":"Fidzianska","year":"1991","journal-title":"Neuropediatrics"},{"key":"R9-5-20240808","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1002\/(SICI)1097-4598(199807)21:7<972::AID-MUS25>3.0.CO;2-R","article-title":"Axonal polyneuropathy in Ehlers-Danlos syndrome.","volume":"21","author":"Muellbacher","year":"1998","journal-title":"Muscle Nerve"},{"key":"R10-5-20240808","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1212\/WNL.34.9.1270-a","article-title":"Ehlers-Danlos in association with tomaculous neuropathy.","volume":"34","author":"Schady","year":"1984","journal-title":"Neurology"},{"key":"R11-5-20240808","doi-asserted-by":"crossref","first-page":"612","DOI":"10.3109\/17453679108994511","article-title":"Recurrent common peroneal palsy in association with the Ehlers-Danlos syndrome. A case report.","volume":"62","author":"Bell","year":"1991","journal-title":"Acta Orthop Scand"},{"key":"R12-5-20240808","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1007\/s00415-005-0056-0","article-title":"Recurrent neuropathy associated with Ehlers-Danlos syndrome.","volume":"253","author":"Voermans","year":"2006","journal-title":"J Neurol"},{"key":"R13-5-20240808","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/0887-8994(95)00003-X","article-title":"Peripheral neuropathy in Ehlers-Danlos syndrome.","volume":"12","author":"Galan","year":"1995","journal-title":"Pediatr Neurol"},{"key":"R14-5-20240808","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.2106\/00004623-197658070-00024","article-title":"Brachial-artery rupture in Ehlers-Danlos syndrome: an unusual cause of high median-nerve palsy. A case report.","volume":"58","author":"Bowers","year":"1976","journal-title":"J Bone Joint Surg Am"},{"key":"R15-5-20240808","first-page":"57","article-title":"Spontaneous gluteal artery rupture resulting in compartment syndrome and sciatic neuropathy. Report of a case in Ehlers-Danlos syndrome.","volume":"53-","author":"Schmalzried","year":"1992","journal-title":"Clin Orthop Relat Res"},{"key":"R16-5-20240808","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.pain.2006.02.022","article-title":"Patients with Ehlers Danlos syndrome and CRPS: a possible association?","volume":"123","author":"Stoler","year":"2006","journal-title":"Pain"}],"container-title":["Journal of Clinical Neuromuscular Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00131402-200912000-00005","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T18:07:59Z","timestamp":1786039679000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00131402-200912000-00005"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,12]]},"references-count":16,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2009]]}},"URL":"https:\/\/doi.org\/10.1097\/cnd.0b013e3181bab6e3","relation":{},"ISSN":["1522-0443"],"issn-type":[{"value":"1522-0443","type":"print"}],"subject":[],"published":{"date-parts":[[2009,12]]}}}