{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:18:04Z","timestamp":1786119484784,"version":"build-2736575974"},"reference-count":24,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2010,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title\/>\n                    <jats:p>A patient with acute purely motor polyneuropathy with positive GD1a ganglioside antibodies who presented with paresis in combination with hyperreflexia is reported. Neurophysiological tests revealed features compatible with acute motor axonal neuropathy. Therapy with intravenous immunoglobulin led to rapid clinical improvement. However, at the time when signs of active denervation appeared on electromyographic testing, the patient developed bilateral papillitis. The pathogenesis of pure motor Guillain-Barr\u00e9 syndrome with hyperreflexia and papillitis is discussed.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1097\/cnd.0b013e3181cc21de","type":"journal-article","created":{"date-parts":[[2010,2,27]],"date-time":"2010-02-27T01:03:34Z","timestamp":1267232614000},"page":"114-119","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":6,"title":["GD1a-Associated Pure Motor Guillain-Barr\u00e9 Syndrome With Hyperreflexia and Bilateral Papillitis"],"prefix":"10.1097","volume":"11","author":[{"given":"Christoph","family":"Neuwirth","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Mojon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markus","family":"Weber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-3-20240808","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1002\/ana.410440512","article-title":"Electrophysiological classification of Guillain-Barre syndrome: clinical associations and outcome. Plasma Exchange\/Sandoglobulin Guillain-Barre Syndrome Trial Group.","volume":"44","author":"Hadden","year":"1998","journal-title":"Ann Neurol"},{"key":"R2-3-20240808","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1002\/ana.410380516","article-title":"Anti-ganglioside GM1 antibodies in Guillain-Barre syndrome and their relationship to Campylobacter jejuni infection.","volume":"38","author":"Rees","year":"1995","journal-title":"Ann Neurol"},{"key":"R3-3-20240808","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1093\/brain\/118.3.597","article-title":"Guillain-Barre syndrome in northern China. Relationship to Campylobacter jejuni infection and anti-glycolipid antibodies.","volume":"118","author":"Ho","year":"1995","journal-title":"Brain"},{"key":"R4-3-20240808","first-page":"932","article-title":"High-dose intravenous immunoglobulins for treatment of optic neuritis in Guillain-Barre syndrome [in German].","volume":"224","author":"Luke","year":"2007","journal-title":"Klin Monatsbl Augenheilkd"},{"key":"R5-3-20240808","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1136\/jnnp.40.2.144","article-title":"Hypertension and papilloedema in the Guillain-Barre syndrome.","volume":"40","author":"Davidson","year":"1977","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"R6-3-20240808","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1002\/mus.880080609","article-title":"Sequential electrodiagnostic abnormalities in acute inflammatory demyelinating polyradiculoneuropathy.","volume":"8","author":"Albers","year":"1985","journal-title":"Muscle Nerve"},{"key":"R7-3-20240808","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1212\/01.WNL.0000153071.71335.E9","article-title":"Patterns and serial changes in electrodiagnostic abnormalities of axonal Guillain-Barre syndrome.","volume":"64","author":"Hiraga","year":"2005","journal-title":"Neurology"},{"key":"R8-3-20240808","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1136\/jnnp.67.2.180","article-title":"Hyperreflexia in Guillain-Barre syndrome: relation with acute motor axonal neuropathy and anti-GM1 antibody.","volume":"67","author":"Kuwabara","year":"1999","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"R9-3-20240808","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1212\/WNL.48.3.717","article-title":"Motor nerve terminal degeneration provides a potential mechanism for rapid recovery in acute motor axonal neuropathy after Campylobacter infection.","volume":"48","author":"Ho","year":"1997","journal-title":"Neurology"},{"key":"R10-3-20240808","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1212\/01.WNL.0000133205.05169.04","article-title":"Does Campylobacter jejuni infection elicit demyelinating Guillain-Barre syndrome?","volume":"63","author":"Kuwabara","year":"2004","journal-title":"Neurology"},{"key":"R11-3-20240808","first-page":"270","article-title":"Guillain-Barre syndrome with nerve conduction blocks at multiple common entrapment sites that rapidly disappeared after plasmapheresis [in Japanese].","volume":"38","author":"Susuki","year":"1998","journal-title":"Rinsho Shinkeigaku"},{"key":"R12-3-20240808","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1111\/j.1529-8027.2007.00153.x","article-title":"Axonal Guillain-Barre syndrome: carbohydrate mimicry and pathophysiology.","volume":"12","author":"Yuki","year":"2007","journal-title":"J Peripher Nerv Syst"},{"key":"R13-3-20240808","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1212\/WNL.61.5.617","article-title":"Acute motor conduction block neuropathy. Another Guillain-Barre syndrome variant.","volume":"61","author":"Capasso","year":"2003","journal-title":"Neurology"},{"key":"R14-3-20240808","doi-asserted-by":"crossref","first-page":"1683","DOI":"10.1212\/01.wnl.0000335160.72184.7d","article-title":"GM1\/GalNAc-GD1a complex: a target for pure motor Guillain-Barre syndrome.","volume":"71","author":"Kaida","year":"2008","journal-title":"Neurology"},{"key":"R15-3-20240808","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1212\/WNL.61.5.598","article-title":"Axonal Guillain-Barre syndrome subtypes: do we need more splitting?","volume":"61","author":"Yuki","year":"2003","journal-title":"Neurology"},{"key":"R16-3-20240808","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.nbd.2007.07.008","article-title":"Anti-ganglioside antibodies alter presynaptic release and calcium influx.","volume":"28","author":"Buchwald","year":"2007","journal-title":"Neurobiol Dis"},{"key":"R17-3-20240808","doi-asserted-by":"crossref","first-page":"1620","DOI":"10.1523\/JNEUROSCI.4279-04.2005","article-title":"Overexpression of GD1a ganglioside sensitizes motor nerve terminals to anti-GD1a antibody-mediated injury in a model of acute motor axonal neuropathy.","volume":"25","author":"Goodfellow","year":"2005","journal-title":"J Neurosci"},{"key":"R18-3-20240808","first-page":"801","article-title":"Fisher syndrome with optic neuropathy [in Japanese].","volume":"112","author":"Koga","year":"2008","journal-title":"Nippon Ganka Gakkai Zasshi"},{"key":"R19-3-20240808","first-page":"571","article-title":"Atypical Fisher syndrome with optic nerve involvement [in Japanese].","volume":"53","author":"Sasaki","year":"2001","journal-title":"No To Shinkei"},{"key":"R20-3-20240808","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/0303-8467(95)00041-H","article-title":"Hydrocephalus in Guillain-Barre syndrome.","volume":"97","author":"Ersahin","year":"1995","journal-title":"Clin Neurol Neurosurg"},{"key":"R21-3-20240808","doi-asserted-by":"crossref","first-page":"2306","DOI":"10.1523\/JNEUROSCI.23-06-02306.2003","article-title":"Functional specialization of the axon initial segment by isoform-specific sodium channel targeting.","volume":"23","author":"Boiko","year":"2003","journal-title":"J Neurosci"},{"key":"R22-3-20240808","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1212\/WNL.43.2.408","article-title":"Sulfated glucuronyl glycolipids and gangliosides in the optic nerve of humans.","volume":"43","author":"Yoshino","year":"1993","journal-title":"Neurology"},{"key":"R23-3-20240808","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1136\/jnnp.73.5.568","article-title":"Central motor conduction in patients with anti-ganglioside antibody associated neuropathy syndromes and hyperreflexia.","volume":"73","author":"Oshima","year":"2002","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"R24-3-20240808","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/S0022-510X(02)00088-6","article-title":"Hyperreflexia in axonal Guillain-Barre syndrome subsequent to Campylobacter jejuni enteritis.","volume":"199","author":"Kuwabara","year":"2002","journal-title":"J Neurol Sci"}],"container-title":["Journal of Clinical Neuromuscular Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00131402-201003000-00003","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T18:16:18Z","timestamp":1786040178000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00131402-201003000-00003"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,3]]},"references-count":24,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2010]]}},"URL":"https:\/\/doi.org\/10.1097\/cnd.0b013e3181cc21de","relation":{},"ISSN":["1522-0443"],"issn-type":[{"value":"1522-0443","type":"print"}],"subject":[],"published":{"date-parts":[[2010,3]]}}}