{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T23:26:52Z","timestamp":1779233212024,"version":"3.51.4"},"reference-count":17,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2012,3]]},"abstract":"<jats:sec>\n            <jats:title>Objective<\/jats:title>\n            <jats:p>Carpal tunnel syndrome is the most common entrapment neuropathy. We explore the clinical use of nerve conduction study in the outcome prediction and preoperative selection for endoscopic carpal tunnel syndrome surgery.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>Sixty-seven patients with carpal tunnel syndrome were prospectively enrolled. Each patient's clinical symptomatic score at baseline and 3 months postsurgery was compared with nerve conduction study parameters of distal motor latency, motor amplitude, motor conduction velocity, distal sensory latency, sensory amplitude, and sensory conduction velocity. A statistical logistic regression model was used to ascertain outcomes.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>Endoscopic surgery resulted in significant improvement for all four major symptoms pain, numbness, paresthesia, and weakness. From multivariate logistic regression, a shorter distal sensory latency is associated with a higher likelihood of a good outcome (<jats:italic toggle=\"yes\">P<\/jats:italic> = 0.058; odds ratio, 0.912; 95% confidence interval, 0.828\u20131.0) only for paresthesia. The other factors were not found to be significant (all <jats:italic toggle=\"yes\">P<\/jats:italic> &gt; 0.10). The area under the curve (AUC) was 0.69 (95% confidence interval for AUC, 0.50\u20130.88). A cutoff of 6.0 ms or lower for sensory latency predicts for good outcome (in terms of paresthesia score) with the sensitivity\/certainty of 84.6% and positive predictive value of 86.8%. A receiver operating characteristic analysis of baseline paresthesia score for good outcome of the paraesthesia domain showed that the AUC was 0.967 (95% confidence interval for AUC, 0\u20131.0). At a cutoff of baseline paraesthesia score of 4 or above, prediction for good outcome achieved a sensitivity of 87.2% and positive predictive value of 97.1%.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>A shorter distal sensory latency is associated with a higher likelihood of a good outcome for paraesthesia. In addition, patients with baseline of 4 or above had correlated with better surgical outcome than those with less severe symptoms. Our data thus suggest that surgical benefit is best seen in patients with moderate symptoms, in combination with electrophysiological evidence of early demyelination, as a possible therapeutic window.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/cnd.0b013e31822b19a5","type":"journal-article","created":{"date-parts":[[2012,2,22]],"date-time":"2012-02-22T10:50:41Z","timestamp":1329907841000},"page":"153-158","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":11,"title":["Outcome Prediction Value of Nerve Conduction Studies for Endoscopic Carpal Tunnel Surgery"],"prefix":"10.1097","volume":"13","author":[{"given":"Yew-Long","family":"Lo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shu-Han","family":"Lim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephanie","family":"Fook-Chong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sau-Ying","family":"Lum","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lam-Chuan","family":"Teoh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fook-Chuan","family":"Yong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-8-20240808","doi-asserted-by":"crossref","first-page":"1923","DOI":"10.1212\/WNL.45.10.1923","article-title":"Low-dose, short term 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estimation.","volume":"129","author":"Mickey","year":"1989","journal-title":"Am J Epidemiol"},{"key":"R10-8-20240808","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1177\/1753193409102380","article-title":"Severity scoring in carpal tunnel syndrome helps predict the value of conservative therapy.","volume":"34","author":"Ollivere","year":"2009","journal-title":"J Hand Surg Eur Vol"},{"key":"R12-8-20240808","doi-asserted-by":"crossref","first-page":"541","DOI":"10.3171\/JNS\/2008\/108\/3\/0541","article-title":"Magnetic resonance imaging compared with electrodiagnostic studies in patients with suspected carpal tunnel syndrome: predicting symptoms, function, and surgical benefit at 1 year.","volume":"108","author":"Jarvk","year":"2008","journal-title":"J Neurosurg"},{"key":"R13-8-20240808","first-page":"786","article-title":"Usefulness of clinical findings, nerve conduction studies and ultrasonography to predict response to surgical release in idiopathic carpal tunnel syndrome.","volume":"27","author":"Naranjo","year":"2009","journal-title":"Clin Exp Rheumatol"},{"key":"R14-8-20240808","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.2106\/00004623-199311000-00002","article-title":"A self-administered questionnaire for the assessment of severity of symptoms and functional status in carpal tunnel syndrome.","volume":"75","author":"Levine","year":"1993","journal-title":"J Bone Joint Surg Am"},{"key":"R16-8-20240808","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1054\/jhsb.2000.0376","article-title":"Value of electrodiagnostic tests in carpal tunnel syndrome.","volume":"25","author":"Porras","year":"2000","journal-title":"J Hand Surg Br"},{"key":"R17-8-20240808","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1302\/0301-620X.85B6.13759","article-title":"Carpal tunnel release. A prospective, randomized study of endoscopic versus limited-open methods.","volume":"85","author":"Wong","year":"2003","journal-title":"J Bone Joint Surg Br"},{"key":"R18-8-20240808","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1016\/S1388-2457(02)00169-4","article-title":"Carpal tunnel syndrome: pathophysiology and clinical neurophysiology.","volume":"113","author":"Werner","year":"2002","journal-title":"Clin Neurophysiol"},{"key":"R19-8-20240808","doi-asserted-by":"crossref","first-page":"565","DOI":"10.2519\/jospt.2004.34.10.565","article-title":"Clinical and electrodiagnostic testing of carpal tunnel syndrome: a narrative review.","volume":"34","author":"MacDermid","year":"2004","journal-title":"J Orthop Sports Phys Ther"},{"key":"R20-8-20240808","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/j.jhsa.2004.01.011","article-title":"Time course and predictors of median nerve conduction after carpal tunnel release.","volume":"29","author":"Rotman","year":"2004","journal-title":"J Hand Surg Am"}],"container-title":["Journal of Clinical Neuromuscular Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/00131402-201203000-00008","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,8]],"date-time":"2024-08-08T23:24:35Z","timestamp":1723159475000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00131402-201203000-00008"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,3]]},"references-count":17,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2012]]}},"URL":"https:\/\/doi.org\/10.1097\/cnd.0b013e31822b19a5","relation":{},"ISSN":["1522-0443"],"issn-type":[{"value":"1522-0443","type":"print"}],"subject":[],"published":{"date-parts":[[2012,3]]}}}