{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T14:23:14Z","timestamp":1750256594721,"version":"3.40.5"},"reference-count":12,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2023,10,19]],"date-time":"2023-10-19T00:00:00Z","timestamp":1697673600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec>\n            <jats:title>Purpose:<\/jats:title>\n            <jats:p>To report and present images of a case in which discrete conjunctival lesions developed in the setting of primary varicella zoster virus infection (ie, chickenpox).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods:<\/jats:title>\n            <jats:p>Case report and literature review.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results:<\/jats:title>\n            <jats:p>This report describes a young, unvaccinated male who developed an acutely painful, red eye in the setting of disseminated primary varicella zoster infection. The cutaneous rash was widespread and included lesions on both eyelids. The patient was found to have multiple discrete de-epithelialized lesions involving the palpebral and bulbar conjunctiva. Throughout the disease course, good visual function was maintained and there was no evidence of intraocular involvement. The ocular surface lesions resolved without sequelae after 1 week of treatment with topical antibiotic ointment.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions:<\/jats:title>\n            <jats:p>Primary varicella zoster infection is an increasingly rare phenomenon in the setting of widespread vaccination. However, unvaccinated or undervaccinated individuals and other at-risk populations remain susceptible to developing severe infections. This case of chickenpox involved discrete conjunctival lesions that resolved without sequelae after conservative treatment with topical antibiotic ointment. While serious ophthalmic complications are uncommon in primary varicella infection, clinicians should be aware of the potential for ocular morbidity in this increasingly rare condition.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/coa.0000000000000022","type":"journal-article","created":{"date-parts":[[2023,10,19]],"date-time":"2023-10-19T04:02:30Z","timestamp":1697688150000},"page":"e0022","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Conjunctival Lesions Secondary to Systemic Varicella Zoster Virus Infection"],"prefix":"10.1097","volume":"2","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9624-9027","authenticated-orcid":false,"given":"Justin J.","family":"Grassmeyer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6836-2695","authenticated-orcid":false,"given":"Kellyn N.","family":"Bellsmith","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allison R.","family":"Bradee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1461-9413","authenticated-orcid":false,"given":"Roma B.","family":"Pegany","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Travis K.","family":"Redd","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","published-online":{"date-parts":[[2023,12]]},"reference":[{"issue":"suppl 4","key":"R1-20241016","doi-asserted-by":"crossref","first-page":"S380","DOI":"10.1093\/infdis\/jiac390","article-title":"Clinical manifestations of varicella: disease is largely forgotten, but it's not gone","volume":"226","author":"Dooling","year":"2022","journal-title":"J Infect 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(Phila)."},{"key":"R6-20241016","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1097\/01.ico.0000224651.19837.6c","article-title":"Ocular manifestations after primary varicella infection","volume":"25","author":"Fern\u00e1ndez de Castro","year":"2006","journal-title":"Cornea"},{"key":"R7-20241016","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1080\/09273948.2017.1383447","article-title":"Review for disease of the year: varicella zoster virus-induced anterior uveitis","volume":"26","author":"Tugal-Tutkun","year":"2018","journal-title":"Ocul Immunol Inflamm."},{"key":"R8-20241016","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/S0008-4182(06)80076-1","article-title":"Panuveitis as presenting sign of chickenpox in a young child","volume":"41","author":"Belfair","year":"2006","journal-title":"Can J Ophthalmol."},{"key":"R9-20241016","first-page":"e44","article-title":"A case of internal ophthalmoplegia associated with varicella zoster","volume":"49 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Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/coa.0000000000000022","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,16]],"date-time":"2024-10-16T23:02:19Z","timestamp":1729119739000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.1097\/coa.0000000000000022"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,19]]},"references-count":12,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.1097\/coa.0000000000000022","relation":{},"ISSN":["2833-6992"],"issn-type":[{"type":"electronic","value":"2833-6992"}],"subject":[],"published":{"date-parts":[[2023,10,19]]},"assertion":[{"value":"2023-07-06","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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