{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T09:18:07Z","timestamp":1790155087749,"version":"4.0.1"},"reference-count":14,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiopulm Phys Ther J"],"published-print":{"date-parts":[[2018,7]]},"abstract":"<jats:sec>\n            <jats:title>Objective:<\/jats:title>\n            <jats:p>The 6-minute walk test (6MWT) is a measure that is routinely used to assess a response to treatment for cardiopulmonary diseases such as pulmonary fibrosis and congestive heart failure. The measure has never been verified as a valid measure of exercise capacity in the highly prevalent patient population of type 2 diabetes (T2DM). This study investigated the correlation between the 6MWT and graded exercise testing (GXT) in an effort to validate the 6MWT as a quality tool for assessing exercise capacity in adults with T2DM.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Research Design and Method:<\/jats:title>\n            <jats:p>This is a secondary data analysis of Program ACTIVE II, a randomized controlled trial designed to assess the effectiveness of 2 behavioral interventions on depression and glycemic outcomes in adults with T2DM. The correlation of 6MWT and predicted VO2 max (PVO2M) using GXT was examined in a subsample of participants at the time of study enrollment and at postintervention.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results:<\/jats:title>\n            <jats:p>PVO2M showed a significant correlation with 6MWT distance both at baseline (r = 0.57, <jats:italic toggle=\"yes\">P<\/jats:italic> = .014) and postintervention (r = 0.66, <jats:italic toggle=\"yes\">P<\/jats:italic> = .037). The regression analysis of baseline data revealed that 6MWT distance alone explained 45% (F = 13.03, <jats:italic toggle=\"yes\">P<\/jats:italic> = .0024) of the variability in PVO2M. When combined with the SF-12 physical health component score (Physical Components Subscale [PCS]), 6MWT explained 66% (F = 13.62, <jats:italic toggle=\"yes\">P<\/jats:italic> &lt; .001) of the variance in PVO2M. After adjusting for PCS, 6MWT distance explained an additional 30% variability in PVO2M.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions:<\/jats:title>\n            <jats:p>Findings from this study indicate that the 6MWT and predicted exercise capacity are significantly correlated. The 6MWT can be used to estimate exercise capacity in adults with T2DM.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/cpt.0000000000000080","type":"journal-article","created":{"date-parts":[[2018,7,3]],"date-time":"2018-07-03T21:30:38Z","timestamp":1530653438000},"page":"124-129","source":"Crossref","is-referenced-by-count":27,"title":["Six-Minute Walk Test as a Predictive Measure of Exercise Capacity in Adults With Type 2 Diabetes"],"prefix":"10.1097","volume":"29","author":[{"given":"Eric","family":"Nolen-Doerr","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Indiana University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kent","family":"Crick","sequence":"additional","affiliation":[{"name":"Diabetes Translational Research Center, Indiana University School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chandan","family":"Saha","sequence":"additional","affiliation":[{"name":"Diabetes Translational Research Center, Indiana University School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary","family":"de Groot","sequence":"additional","affiliation":[{"name":"Diabetes Translational Research Center, Indiana University School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yegan","family":"Pillay","sequence":"additional","affiliation":[{"name":"Ohio University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jay H.","family":"Shubrook","sequence":"additional","affiliation":[{"name":"Primary Care Department, Touro University California"},{"name":"Ohio University Heritage College of Osteopathic Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Donley","sequence":"additional","affiliation":[{"name":"Department of Human Performance\u2014Exercise Physiology, West Virginia University, Morgantown, WV"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W. Guyton","family":"Hornsby","sequence":"additional","affiliation":[{"name":"Department of Human Performance\u2014Exercise Physiology, West Virginia University, Morgantown, WV"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"issue":"suppl 1","key":"R2-20230816","first-page":"S36","article-title":"Prevention or delay of type 2 diabetes","volume":"39","year":"2016","journal-title":"Diabetes Care."},{"issue":"9","key":"R3-20230816","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1016\/S0002-9149(01)01975-0","article-title":"Prognostic usefulness of the six-minute walk in patients with advanced congestive heart failure secondary to ischemic or nonischemic cardiomyopathy","volume":"88","author":"Shah","year":"2001","journal-title":"Am J Cardiol."},{"key":"R4-20230816","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1097\/HCR.0b013e3181c565e4","article-title":"Six-minute walk distance in patients with severe end-stage COPD: Association with survival after inpatient pulmonary rehabilitation","volume":"30","author":"Enfield","year":"2010","journal-title":"J Cardiopulm Rehabil Prev."},{"key":"R5-20230816","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1164\/rccm.200604-488OC","article-title":"Idiopathic pulmonary fibrosis: Prognostic value of changes in physiology and six-minute-walk test","volume":"174","author":"Flaherty","year":"2006","journal-title":"Am J Respir Crit Care Med."},{"key":"R6-20230816","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1164\/ajrccm.161.2.9906015","article-title":"Clinical correlates and prognostic significance of six-minute walk test in patients with primary pulmonary hypertension. Comparison with cardiopulmonary exercise testing","volume":"161","author":"Miyamoto","year":"2000","journal-title":"Am J Respir Crit Care Med."},{"issue":"6","key":"R7-20230816","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1183\/09031936.00150414","article-title":"An official systematic review of the European Respiratory Society\/American Thoracic Society: Measurement properties of field walking tests in chronic respiratory disease","volume":"44","author":"Singh","year":"2014","journal-title":"Eur Respir J."},{"key":"R8-20230816","first-page":"227","article-title":"Six-minute walk test in non-insulin-dependent diabetes mellitus patients living in Northwest Africa","volume":"5","author":"Latiri","year":"2012","journal-title":"Diabetes Metab Syndr Obes."},{"issue":"1","key":"R9-20230816","doi-asserted-by":"crossref","first-page":"18","DOI":"10.2337\/diaspect.23.1.18","article-title":"A model of community-based behavioral intervention for depression in diabetes: Program ACTIVE","volume":"23","author":"de Groot","year":"2010","journal-title":"Diabetes Spectr."},{"issue":"1","key":"R11-20230816","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1164\/ajrccm.166.1.at1102","article-title":"Committee on proficiency standards for clinical pulmonary function laboratories ATS statement: Guidelines for the six-minute walk test","volume":"166","year":"2002","journal-title":"Am J Respir Crit Care Med."},{"key":"R12-20230816","first-page":"675","article-title":"An experimental study of physical fitness of Air Force personnel","volume":"10","author":"Balke","year":"1959","journal-title":"U S Armed Forces Med J."},{"issue":"5","key":"R13-20230816","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1001\/jama.2013.284427","article-title":"2014 evidence-based guideline for the management of high blood pressure in Adults: Report from the panel members appointed to the Eighth Joint National Committee (JNC 8)","volume":"311","author":"James","year":"2014","journal-title":"JAMA."},{"issue":"7","key":"R14-20230816","doi-asserted-by":"crossref","first-page":"1334","DOI":"10.1249\/MSS.0b013e318213fefb","article-title":"American College of Sports Medicine position stand. The quantity and quality of exercise for developing and maintaining cardiorespiratory, musculoskeletal, and neuromotor fitness in apparently healthy adults: Guidance for prescribing exercise","volume":"43","author":"Garber","year":"2011","journal-title":"Med Sci Sports Exerc."},{"issue":"7","key":"R16-20230816","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1001\/jama.1989.03430070055030","article-title":"Functional status and well-being of patients with chronic conditions","volume":"262","author":"Stewart","year":"1989","journal-title":"JAMA."},{"issue":"2","key":"R17-20230816","doi-asserted-by":"crossref","first-page":"203","DOI":"10.2337\/dc06-1128","article-title":"Physical activity in U.S. adults with diabetes and at risk for developing diabetes, 2003","volume":"30","author":"Morrato","year":"2007","journal-title":"Diabetes Care."}],"container-title":["Cardiopulmonary Physical Therapy Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/01823246-201807000-00005","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,16]],"date-time":"2023-08-16T01:04:13Z","timestamp":1692147853000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/01823246-201807000-00005"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7]]},"references-count":14,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018]]}},"URL":"https:\/\/doi.org\/10.1097\/cpt.0000000000000080","relation":{},"ISSN":["1541-7891","2374-8907"],"issn-type":[{"value":"1541-7891","type":"print"},{"value":"2374-8907","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,7]]}}}