{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T16:52:57Z","timestamp":1790700777753,"version":"4.1.0"},"reference-count":108,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,1]]},"DOI":"10.1097\/crd.0000000000000032","type":"journal-article","created":{"date-parts":[[2014,6,19]],"date-time":"2014-06-19T20:07:23Z","timestamp":1403208443000},"page":"18-25","source":"Crossref","is-referenced-by-count":16,"title":["Physical Activity in the Management of Patients with Coronary Artery Disease"],"prefix":"10.1097","volume":"23","author":[{"given":"James","family":"Backshall","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary A.","family":"Ford","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bilal","family":"Bawamia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louise","family":"Quinn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mike","family":"Trenell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vijay","family":"Kunadian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R3-3-20210203","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1161\/01.CIR.102.9.975","article-title":"Physical activity and coronary heart disease in men: the Harvard Alumni Health Study.","volume":"102","author":"Sesso","year":"2000","journal-title":"Circulation"},{"key":"R4-3-20210203","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1097\/01.hjr.0000198923.80555.b7","article-title":"Long-term physical activity in leisure time and mortality from coronary heart disease, stroke, respiratory diseases, and cancer. The Copenhagen City Heart Study.","volume":"13","author":"Schnohr","year":"2006","journal-title":"Eur J Cardiovasc Prev Rehabil"},{"key":"R6-3-20210203","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1161\/CIRCULATIONAHA.110.010710","article-title":"Dose response between physical activity and risk of coronary heart disease: a meta-analysis.","volume":"124","author":"Sattelmair","year":"2011","journal-title":"Circulation"},{"key":"R7-3-20210203","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1136\/hrt.2006.087478","article-title":"Lifetime physical activity patterns and risk of coronary heart disease.","volume":"92","author":"Rothenbacher","year":"2006","journal-title":"Heart"},{"key":"R9-3-20210203","doi-asserted-by":"crossref","first-page":"f5577","DOI":"10.1136\/bmj.f5577","article-title":"Comparative effectiveness of exercise and drug interventions on mortality outcomes: metaepidemiological study.","volume":"347","author":"Naci","year":"2013","journal-title":"BMJ"},{"key":"R10-3-20210203","doi-asserted-by":"crossref","first-page":"1635","DOI":"10.1093\/eurheartj\/ehs092","article-title":"European Association for Cardiovascular Prevention Rehabilitation (EACPR); ESC Committee for Practice Guidelines (CPG). European guidelines on cardiovascular disease prevention in clinical practice (version 2012). The Fifth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of nine societies and by invited experts).","volume":"33","author":"Perk","year":"2012","journal-title":"Eur Heart J"},{"key":"R11-3-20210203","first-page":"6","article-title":"The impact of moderate aerobic physical training on left ventricular mass, exercise capacity and blood pressure response during treadmill testing in borderline and mildly hypertensive males.","volume":"52","author":"Pitsavos","year":"2011","journal-title":"Hellenic J Cardiol"},{"key":"R12-3-20210203","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1056\/NEJM200105033441801","article-title":"Finnish Diabetes Prevention Study Group. Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance.","volume":"344","author":"Tuomilehto","year":"2001","journal-title":"N Engl J Med"},{"key":"R14-3-20210203","doi-asserted-by":"crossref","first-page":"2110","DOI":"10.1161\/CIRCULATIONAHA.107.729939","article-title":"Physical activity and reduced risk of cardiovascular events: potential mediating mechanisms.","volume":"116","author":"Mora","year":"2007","journal-title":"Circulation"},{"key":"R15-3-20210203","doi-asserted-by":"crossref","first-page":"1286","DOI":"10.1001\/archinte.162.11.1286","article-title":"Relationship between physical activity and inflammation among apparently healthy middle-aged and older US adults.","volume":"162","author":"Abramson","year":"2002","journal-title":"Arch Intern Med"},{"key":"R16-3-20210203","doi-asserted-by":"crossref","first-page":"729","DOI":"10.2217\/fca.12.34","article-title":"Exercise-based cardiac rehabilitation in patients with coronary heart disease: meta-analysis outcomes revisited.","volume":"8","author":"Oldridge","year":"2012","journal-title":"Future Cardiol"},{"key":"R17-3-20210203","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/HJR.0b013e3283313592","article-title":"Cardiac Rehabilitation Section of the European Association of Cardiovascular Prevention and Rehabilitation. Secondary prevention through cardiac rehabilitation: from knowledge to implementation. A position paper from the Cardiac Rehabilitation Section of the European Association of Cardiovascular Prevention and Rehabilitation.","volume":"17","author":"Piepoli","year":"2010","journal-title":"Eur J Cardiovasc Prev Rehabil"},{"key":"R18-3-20210203","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1097\/00005768-200002000-00024","article-title":"Leisure-time physical activities and their relationship to cardiorespiratory fitness in healthy men and women 18-95 years old.","volume":"32","author":"Talbot","year":"2000","journal-title":"Med Sci Sports Exerc"},{"key":"R20-3-20210203","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1177\/1741826710389379","article-title":"Self-reported physical inactivity predicts survival after hospitalization for heart disease.","volume":"18","author":"Oerkild","year":"2011","journal-title":"Eur J Cardiovasc Prev Rehabil"},{"key":"R21-3-20210203","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.jacc.2009.01.078","article-title":"Cardiac rehabilitation and survival in older coronary patients.","volume":"54","author":"Suaya","year":"2009","journal-title":"J Am Coll Cardiol"},{"key":"R22-3-20210203","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1093\/gerona\/62.7.731","article-title":"Frailty: an emerging research and clinical paradigmissues and controversies.","volume":"62","author":"Bergman","year":"2007","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"R23-3-20210203","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.cger.2010.08.001","article-title":"Exercise as an intervention for frailty.","volume":"27","author":"Liu","year":"2011","journal-title":"Clin Geriatr Med"},{"key":"R24-3-20210203","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1007\/s12170-011-0186-0","article-title":"Frailty in patients with cardiovascular disease: why, when, and how to measure.","volume":"5","author":"Afilalo","year":"2011","journal-title":"Curr Cardiovasc Risk Rep"},{"key":"R25-3-20210203","doi-asserted-by":"crossref","first-page":"2397","DOI":"10.1161\/CIRCULATIONAHA.111.025452","article-title":"Frailty is independently associated with short-term outcomes for elderly patients with non-ST-segment elevation myocardial infarction.","volume":"124","author":"Ekerstad","year":"2011","journal-title":"Circulation"},{"key":"R26-3-20210203","doi-asserted-by":"crossref","first-page":"173","DOI":"10.7326\/0003-4819-134-3-200102060-00007","article-title":"Sex differences in 2-year mortality after hospital discharge for myocardial infarction.","volume":"134","author":"Vaccarino","year":"2001","journal-title":"Ann Intern Med"},{"key":"R27-3-20210203","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/j.amepre.2004.02.007","article-title":"Physical activity decreases cardiovascular disease risk in women: review and meta-analysis.","volume":"26","author":"Oguma","year":"2004","journal-title":"Am J Prev Med"},{"key":"R29-3-20210203","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1001\/jama.286.13.1621","article-title":"Depression in patients recovering from a myocardial infarction.","volume":"286","author":"Ziegelstein","year":"2001","journal-title":"JAMA"},{"key":"R30-3-20210203","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/S0002-9149(03)00719-7","article-title":"Effect of smoking and sedentary behavior on the association between depressive symptoms and mortality from coronary heart disease.","volume":"92","author":"Brummett","year":"2003","journal-title":"Am J Cardiol"},{"key":"R31-3-20210203","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1136\/hrt.2010.209767","article-title":"Depressive symptoms, physical inactivity and risk of cardiovascular mortality in older adults: the Cardiovascular Health Study.","volume":"97","author":"Win","year":"2011","journal-title":"Heart"},{"key":"R32-3-20210203","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1249\/01.MSS.0000125997.63493.13","article-title":"Exercise, depression, and mortality after myocardial infarction in the ENRICHD trial.","volume":"36","author":"Blumenthal","year":"2004","journal-title":"Med Sci Sports Exerc"},{"key":"R33-3-20210203","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1016\/j.amjmed.2007.03.026","article-title":"Impact of cardiac rehabilitation on depression and its associated mortality.","volume":"120","author":"Milani","year":"2007","journal-title":"Am J Med"},{"key":"R34-3-20210203","doi-asserted-by":"crossref","first-page":"3481","DOI":"10.1161\/CIRCULATIONAHA.105.537878","article-title":"Pathophysiology of coronary artery disease.","volume":"111","author":"Libby","year":"2005","journal-title":"Circulation"},{"key":"R35-3-20210203","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1161\/01.CIR.95.3.594","article-title":"Tissue factor modulates the thrombogenicity of human atherosclerotic plaques.","volume":"95","author":"Toschi","year":"1997","journal-title":"Circulation"},{"key":"R36-3-20210203","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.jacc.2006.10.039","article-title":"Atherosclerosis regression, vascular remodeling, and plaque stabilization.","volume":"49","author":"Klein","year":"2007","journal-title":"J Am Coll Cardiol"},{"key":"R37-3-20210203","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1161\/hc0802.104327","article-title":"Relationship between coronary artery remodeling and plaque vulnerability.","volume":"105","author":"Varnava","year":"2002","journal-title":"Circulation"},{"key":"R38-3-20210203","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.2174\/138920111798281063","article-title":"Exercise-induced modulation of endothelial nitric oxide production.","volume":"12","author":"Gielen","year":"2011","journal-title":"Curr Pharm Biotechnol"},{"key":"R40-3-20210203","doi-asserted-by":"crossref","first-page":"3152","DOI":"10.1161\/01.CIR.0000074229.93804.5C","article-title":"Regular physical activity improves endothelial function in patients with coronary artery disease by increasing phosphorylation of endothelial nitric oxide synthase.","volume":"107","author":"Hambrecht","year":"2003","journal-title":"Circulation"},{"issue":"Pt 1","key":"R41-3-20210203","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1113\/jphysiol.2004.068197","article-title":"Effect of exercise training on endothelium-derived nitric oxide function in humans.","volume":"561","author":"Green","year":"2004","journal-title":"J Physiol"},{"key":"R42-3-20210203","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.2165\/00007256-200333140-00001","article-title":"Exercise and the nitric oxide vasodilator system.","volume":"33","author":"Maiorana","year":"2003","journal-title":"Sports Med"},{"key":"R43-3-20210203","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1139\/h05-133","article-title":"Vascular nitric oxide and oxidative stress: determinants of endothelial adaptations to cardiovascular disease and to physical activity.","volume":"30","author":"Rush","year":"2005","journal-title":"Can J Appl Physiol"},{"key":"R44-3-20210203","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1111\/j.1749-6632.2012.06480.x","article-title":"LDL-cholesterol versus HDL-cholesterol in the atherosclerotic plaque: inflammatory resolution versus thrombotic chaos.","volume":"1254","author":"Badimon","year":"2012","journal-title":"Ann N Y Acad Sci"},{"key":"R45-3-20210203","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1056\/NEJMoa064278","article-title":"Treating to New Targets Investigators. HDL cholesterol, very low levels of LDL cholesterol, and cardiovascular events.","volume":"357","author":"Barter","year":"2007","journal-title":"N Engl J Med"},{"key":"R46-3-20210203","doi-asserted-by":"crossref","first-page":"1905","DOI":"10.1161\/CIRCULATIONAHA.111.066589","article-title":"Cholesterol efflux and atheroprotection: advancing the concept of reverse cholesterol transport.","volume":"125","author":"Rosenson","year":"2012","journal-title":"Circulation"},{"key":"R47-3-20210203","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.1161\/01.CIR.0000013424.28206.8F","article-title":"High-density lipoprotein restores endothelial function in hypercholesterolemic men.","volume":"105","author":"Spieker","year":"2002","journal-title":"Circulation"},{"key":"R49-3-20210203","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0021-9150(01)00651-7","article-title":"HDL and arteriosclerosis: beyond reverse cholesterol transport.","volume":"161","author":"Nofer","year":"2002","journal-title":"Atherosclerosis"},{"key":"R50-3-20210203","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1515\/CCLM.2004.254","article-title":"The apoBapoA-I ratio is better than the cholesterol ratios to estimate the balance between plasma proatherogenic and antiatherogenic lipoproteins and to predict coronary risk.","volume":"42","author":"Walldius","year":"2004","journal-title":"Clin Chem Lab Med"},{"key":"R51-3-20210203","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1177\/0003319710373746","article-title":"Moderate physical activity is associated with lower ApoBApoA-I ratios independently of other risk factors in healthy, middle-aged men.","volume":"61","author":"Behre","year":"2010","journal-title":"Angiology"},{"key":"R52-3-20210203","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1056\/NEJM199807023390103","article-title":"Effects of diet and exercise in men and postmenopausal women with low levels of HDL cholesterol and high levels of LDL cholesterol.","volume":"339","author":"Stefanick","year":"1998","journal-title":"N Engl J Med"},{"key":"R53-3-20210203","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1038\/sj.ijo.0802959","article-title":"Aerobic exercise, lipids and lipoproteins in overweight and obese adults: a meta-analysis of randomized controlled trials.","volume":"29","author":"Kelley","year":"2005","journal-title":"Int J Obes (Lond)"},{"key":"R54-3-20210203","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1001\/jama.298.3.299","article-title":"Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women.","volume":"298","author":"Nordestgaard","year":"2007","journal-title":"JAMA"},{"key":"R55-3-20210203","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1161\/CIRCULATIONAHA.106.637793","article-title":"Triglycerides and the risk of coronary heart disease: 10,158 incident cases among 262,525 participants in 29 Western prospective studies.","volume":"115","author":"Sarwar","year":"2007","journal-title":"Circulation"},{"key":"R56-3-20210203","doi-asserted-by":"crossref","first-page":"985902","DOI":"10.1155\/2012\/985902","article-title":"Combined effects of aerobic exercise and diet on lipids and lipoproteins in overweight and obese adults: a meta-analysis.","volume":"2012","author":"Kelley","year":"2012","journal-title":"J Obes"},{"key":"R57-3-20210203","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1189\/jlb.0607338","article-title":"Chemokine and cytokine processing by matrix metalloproteinases and its effect on leukocyte migration and inflammation.","volume":"82","author":"Van Lint","year":"2007","journal-title":"J Leukoc Biol"},{"key":"R58-3-20210203","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/S0021-9150(03)00251-X","article-title":"Different expression of MMPsTIMP-1 in human atherosclerotic lesions. Relation to plaque features and vascular bed.","volume":"170","author":"Orbe","year":"2003","journal-title":"Atherosclerosis"},{"key":"R59-3-20210203","doi-asserted-by":"crossref","first-page":"2493","DOI":"10.1172\/JCI117619","article-title":"Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques.","volume":"94","author":"Galis","year":"1994","journal-title":"J Clin Invest"},{"key":"R60-3-20210203","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/S0828-282X(08)70602-0","article-title":"Relationships of adiponectin and matrix metalloproteinase-9 to tissue inhibitor of metalloproteinase-1 ratio with coronary plaque morphology in patients with acute coronary syndrome.","volume":"24","author":"Cheng","year":"2008","journal-title":"Can J Cardiol"},{"key":"R61-3-20210203","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.diabet.2009.11.004","article-title":"Exercise ameliorates serum MMP-9 and TIMP-2 levels in patients with type 2 diabetes.","volume":"36","author":"Kadoglou","year":"2010","journal-title":"Diabetes Metab"},{"key":"R62-3-20210203","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1159\/000321174","article-title":"Effects of exercise training on the severity and composition of atherosclerotic plaque in apoE-deficient mice.","volume":"48","author":"Kadoglou","year":"2011","journal-title":"J Vasc Res"},{"key":"R63-3-20210203","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.atherosclerosis.2011.01.036","article-title":"Exercise attenuates matrix metalloproteinase activity in preexisting atherosclerotic plaque.","volume":"216","author":"Shon","year":"2011","journal-title":"Atherosclerosis"},{"key":"R64-3-20210203","doi-asserted-by":"crossref","first-page":"520258","DOI":"10.1155\/2010\/520258","article-title":"The role of exercise-induced myokines in muscle homeostasis and the defense against chronic diseases.","volume":"2010","author":"Brandt","year":"2010","journal-title":"J Biomed Biotechnol"},{"key":"R66-3-20210203","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1016\/S0140-6736(12)60110-X","article-title":"The interleukin-6 receptor as a target for prevention of coronary heart disease: A Mendelian randomisation analysis.","volume":"379","author":"Hingorani","year":"2012","journal-title":"Lancet"},{"key":"R67-3-20210203","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.ijcard.2004.08.073","article-title":"Exercise training modulates cytokines activity in coronary heart disease patients.","volume":"100","author":"Goldhammer","year":"2005","journal-title":"Int J Cardiol"},{"key":"R68-3-20210203","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1249\/MSS.0b013e3181b117ca","article-title":"Effects of resistance or aerobic exercise training on interleukin-6, C-reactive protein, and body composition.","volume":"42","author":"Donges","year":"2010","journal-title":"Med Sci Sports Exerc"},{"key":"R69-3-20210203","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1093\/ajcn\/79.4.544","article-title":"Diet-induced weight loss, exercise, and chronic inflammation in older, obese adults: a randomized controlled clinical trial.","volume":"79","author":"Nicklas","year":"2004","journal-title":"Am J Clin Nutr"},{"key":"R70-3-20210203","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1161\/ATVBAHA.110.207415","article-title":"Recent advances on the role of cytokines in atherosclerosis.","volume":"31","author":"Ait-Oufella","year":"2011","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"R71-3-20210203","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1161\/01.ATV.0000124102.11472.36","article-title":"CXCL16SR-PSOX is an interferon-gamma-regulated chemokine and scavenger receptor expressed in atherosclerotic lesions.","volume":"24","author":"Wuttge","year":"2004","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"R72-3-20210203","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1038\/nm1459","article-title":"Apoptosis of vascular smooth muscle cells induces features of plaque vulnerability in atherosclerosis.","volume":"12","author":"Clarke","year":"2006","journal-title":"Nat Med"},{"key":"R73-3-20210203","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1097\/FJC.0b013e318198fe60","article-title":"Role of FasFas-L in vascular cell apoptosis.","volume":"53","author":"Stoneman","year":"2009","journal-title":"J Cardiovasc Pharmacol"},{"key":"R74-3-20210203","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.atherosclerosis.2007.03.019","article-title":"Interferon-beta attenuates angiotensin II-accelerated atherosclerosis and vascular remodeling in apolipoprotein E deficient mice.","volume":"197","author":"Zhang","year":"2008","journal-title":"Atherosclerosis"},{"key":"R75-3-20210203","doi-asserted-by":"crossref","first-page":"592","DOI":"10.4049\/jimmunol.178.1.592","article-title":"An inflammatory pathway of IFN-gamma production in coronary atherosclerosis.","volume":"178","author":"Ranjbaran","year":"2007","journal-title":"J Immunol"},{"key":"R76-3-20210203","doi-asserted-by":"crossref","first-page":"593","DOI":"10.2116\/analsci.17.593","article-title":"Highly sensitive determination of plasma cytokines by time-resolved fluoroimmunoassay; effect of bicycle exercise on plasma level of interleukin-1 alpha (IL-1 alpha), tumor necrosis factor alpha (TNF alpha), and interferon gamma (IFN gamma).","volume":"17","author":"Kimura","year":"2001","journal-title":"Anal Sci"},{"key":"R77-3-20210203","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1016\/j.intimp.2010.08.008","article-title":"Combined exercise training reduces IFN- and IL-17 levels in the plasma and the supernatant of peripheral blood mononuclear cells in women with multiple sclerosis.","volume":"10","author":"Golzari","year":"2010","journal-title":"Int Immunopharmacol"},{"key":"R78-3-20210203","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1253\/circj.CJ-08-1146","article-title":"Expression levels of Toll-like receptor genes in coronary atherosclerotic lesions of patients with acute coronary syndrome or stable angina pectoris.","volume":"73","author":"Fukushima","year":"2009","journal-title":"Circ J"},{"key":"R79-3-20210203","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1016\/j.atherosclerosis.2011.06.020","article-title":"Myeloid related proteins activate Toll-like receptor 4 in human acute coronary syndromes.","volume":"218","author":"Yonekawa","year":"2011","journal-title":"Atherosclerosis"},{"key":"R80-3-20210203","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1139\/H09-036","article-title":"Toll-like receptor signalling induced by endurance exercise.","volume":"34","author":"Francaux","year":"2009","journal-title":"Appl Physiol Nutr Metab"},{"key":"R81-3-20210203","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1093\/gerona\/60.10.1315","article-title":"Chronic resistance exercise training improves natural killer cell activity in older women.","volume":"60","author":"McFarlin","year":"2005","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"R82-3-20210203","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1093\/gerona\/61.4.388","article-title":"Physical activity status, but not age, influences inflammatory biomarkers and toll-like receptor 4.","volume":"61","author":"McFarlin","year":"2006","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"R83-3-20210203","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1056\/NEJMoa032804","article-title":"C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease.","volume":"350","author":"Danesh","year":"2004","journal-title":"N Engl J Med"},{"key":"R84-3-20210203","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1007\/BF03256418","article-title":"Review of the relationship between C-reactive protein and exercise.","volume":"15","author":"Michigan","year":"2011","journal-title":"Mol Diagn Ther"},{"key":"R85-3-20210203","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1249\/MSS.0b013e3181c03a43","article-title":"Exercise without weight loss does not reduce C-reactive protein: the INFLAME study.","volume":"42","author":"Church","year":"2010","journal-title":"Med Sci Sports Exerc"},{"key":"R86-3-20210203","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1016\/j.ahj.2006.04.019","article-title":"Response of high-sensitivity C-reactive protein to exercise training in an at-risk population.","volume":"152","author":"Huffman","year":"2006","journal-title":"Am Heart J"},{"key":"R87-3-20210203","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1007\/s00421-010-1488-5","article-title":"The effect of aerobic versus strength-based training on high-sensitivity C-reactive protein in older adults.","volume":"110","author":"Martins","year":"2010","journal-title":"Eur J Appl Physiol"},{"key":"R88-3-20210203","doi-asserted-by":"crossref","first-page":"181","DOI":"10.2165\/00007256-200434030-00004","article-title":"Exercise and training effects on blood haemostasis in health and disease: an update.","volume":"34","author":"El-Sayed","year":"2004","journal-title":"Sports Med"},{"key":"R89-3-20210203","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1007\/s11373-006-9105-7","article-title":"Exercise prescription and thrombogenesis.","volume":"13","author":"Wang","year":"2006","journal-title":"J Biomed Sci"},{"key":"R90-3-20210203","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1007\/s00421-010-1640-2","article-title":"Blood coagulation and fibrinolysis in healthy, untrained subjects: effects of different exercise intensities controlled by individual anaerobic threshold.","volume":"111","author":"Menzel","year":"2011","journal-title":"Eur J Appl Physiol"},{"key":"R91-3-20210203","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1007\/s11239-007-0092-y","article-title":"Age-related effects of regular physical activity on hemostatic factors in men.","volume":"26","author":"Sugawara","year":"2008","journal-title":"J Thromb Thrombolysis"},{"key":"R92-3-20210203","doi-asserted-by":"crossref","first-page":"1448","DOI":"10.1161\/CIRCRESAHA.111.241117","article-title":"Exercise protects against myocardial ischemia-reperfusion injury via stimulation of (3)-adrenergic receptors and increased nitric oxide signaling: role of nitrite and nitrosothiols.","volume":"108","author":"Calvert","year":"2011","journal-title":"Circ Res"},{"key":"R93-3-20210203","doi-asserted-by":"crossref","first-page":"1790","DOI":"10.1093\/eurheartj\/eht111","article-title":"Role of exercise in the prevention of cardiovascular disease: results, mechanisms, and new perspectives.","volume":"34","author":"Schuler","year":"2013","journal-title":"Eur Heart J"},{"key":"R94-3-20210203","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1161\/01.RES.0000141145.78900.44","article-title":"Influence of mechanical, cellular, and molecular factors on collateral artery growth (arteriogenesis).","volume":"95","author":"Heil","year":"2004","journal-title":"Circ Res"},{"key":"R96-3-20210203","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1186\/1745-6215-12-92","article-title":"A meta-analysis of the effects of exercise training on left ventricular remodeling following myocardial infarction: start early and go longer for greatest exercise benefits on remodeling.","volume":"12","author":"Haykowsky","year":"2011","journal-title":"Trials"},{"key":"R97-3-20210203","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1097\/01.HCR.0000270693.16882.d9","article-title":"A re-examination of the metabolic equivalent concept in individuals with coronary heart disease.","volume":"27","author":"Savage","year":"2007","journal-title":"J Cardiopulm Rehabil Prev"},{"key":"R98-3-20210203","doi-asserted-by":"crossref","first-page":"1637","DOI":"10.1161\/CIRCULATIONAHA.110.948349","article-title":"Exercise and physical activity: clinical outcomes and applications.","volume":"122","author":"Kokkinos","year":"2010","journal-title":"Circulation"},{"key":"R99-3-20210203","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1007\/s00421-010-1682-5","article-title":"Interval training for patients with coronary artery disease: a systematic review.","volume":"111","author":"Cornish","year":"2011","journal-title":"Eur J Appl Physiol"},{"key":"R100-3-20210203","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1097\/01.hjr.0000131677.96762.0c","article-title":"High intensity aerobic interval exercise is superior to moderate intensity exercise for increasing aerobic capacity in patients with coronary artery disease.","volume":"11","author":"Rognmo","year":"2004","journal-title":"Eur J Cardiovasc Prev Rehabil"},{"key":"R101-3-20210203","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1016\/j.ahj.2009.10.003","article-title":"Aerobic interval training versus continuous moderate exercise after coronary artery bypass surgery: a randomized study of cardiovascular effects and quality of life.","volume":"158","author":"Moholdt","year":"2009","journal-title":"Am Heart J"},{"key":"R102-3-20210203","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1016\/j.ahj.2009.08.021","article-title":"High-intensity interval training may reduce in-stent restenosis following percutaneous coronary intervention with stent implantation A randomized controlled trial evaluating the relationship to endothelial function and inflammation.","volume":"158","author":"Munk","year":"2009","journal-title":"Am Heart J"},{"key":"R103-3-20210203","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1177\/0269215511405229","article-title":"Aerobic interval training increases peak oxygen uptake more than usual care exercise training in myocardial infarction patients: a randomized controlled study.","volume":"26","author":"Moholdt","year":"2012","journal-title":"Clin Rehabil"},{"key":"R104-3-20210203","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1161\/01.CIR.0000024413.15949.ED","article-title":"Prediction of long-term prognosis in 12 169 men referred for cardiac rehabilitation.","volume":"106","author":"Kavanagh","year":"2002","journal-title":"Circulation"},{"key":"R105-3-20210203","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1177\/1741826710393196","article-title":"Intensity versus duration of cycling, impact on all-cause and coronary heart disease mortality: the Copenhagen City Heart Study.","volume":"19","author":"Schnohr","year":"2012","journal-title":"Eur J Prev Cardiol"},{"key":"R106-3-20210203","doi-asserted-by":"crossref","first-page":"1994","DOI":"10.1001\/jama.288.16.1994","article-title":"Exercise type and intensity in relation to coronary heart disease in men.","volume":"288","author":"Tanasescu","year":"2002","journal-title":"JAMA"},{"key":"R107-3-20210203","doi-asserted-by":"crossref","first-page":"37","DOI":"10.3810\/psm.2001.02.366","article-title":"Preventing coronary heart disease: the role of physical activity.","volume":"29","author":"Lee","year":"2001","journal-title":"Phys Sportsmed"},{"key":"R108-3-20210203","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1136\/bjsm.25.2.90","article-title":"Factors affecting adherence of end-stage renal disease patients to an exercise programme.","volume":"25","author":"Williams","year":"1991","journal-title":"Br J Sports Med"},{"key":"R109-3-20210203","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1123\/jpah.8.1.104","article-title":"Factors predicting adherence to 9 months of supervised exercise in healthy older women.","volume":"8","author":"Visek","year":"2011","journal-title":"J Phys Act Health"},{"key":"R110-3-20210203","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1097\/01.hjr.0000086303.28200.50","article-title":"Working Group on Cardiac Rehabilitation and Exercise Physiology. European Society of Cardiology. Physical activity for primary and secondary prevention. Position paper of the Working Group on Cardiac Rehabilitation and Exercise Physiology of the European Society of Cardiology.","volume":"10","author":"Giannuzzi","year":"2003","journal-title":"Eur J Cardiovasc Prev Rehabil"},{"key":"R111-3-20210203","doi-asserted-by":"crossref","first-page":"2535","DOI":"10.1001\/jama.1982.03320430039028","article-title":"Incidence of death during jogging in Rhode Island from 1975 through 1980.","volume":"247","author":"Thompson","year":"1982","journal-title":"JAMA"},{"key":"R112-3-20210203","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1001\/jama.281.10.921","article-title":"Plaque rupture and sudden death related to exertion in men with coronary artery disease.","volume":"281","author":"Burke","year":"1999","journal-title":"JAMA"},{"key":"R113-3-20210203","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1056\/NEJMoa1106468","article-title":"Race Associated Cardiac Arrest Event Registry (RACER) Study Group. Cardiac arrest during long-distance running races.","volume":"366","author":"Kim","year":"2012","journal-title":"N Engl J Med"},{"key":"R114-3-20210203","doi-asserted-by":"crossref","first-page":"2358","DOI":"10.1161\/CIRCULATIONAHA.107.181485","article-title":"American Heart Association Council on Nutrition, Physical Activity, and Metabolism; American Heart Association Council on Clinical Cardiology; American College of Sports Medicine. Exercise and acute cardiovascular events placing the risks into perspective: a scientific statement from the American Heart Association Council on Nutrition, Physical Activity, and Metabolism and the Council on Clinical Cardiology.","volume":"115","author":"Thompson","year":"2007","journal-title":"Circulation"},{"key":"R115-3-20210203","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1159\/000083433","article-title":"Safety of cardiac rehabilitation in a medically supervised, community-based program.","volume":"103","author":"Scheinowitz","year":"2005","journal-title":"Cardiology"},{"key":"R116-3-20210203","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1056\/NEJM200011093431902","article-title":"Triggering of sudden death from cardiac causes by vigorous exertion.","volume":"343","author":"Albert","year":"2000","journal-title":"N Engl J Med"},{"key":"R117-3-20210203","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1056\/NEJM198410043111402","article-title":"The incidence of primary cardiac arrest during vigorous exercise.","volume":"311","author":"Siscovick","year":"1984","journal-title":"N Engl J Med"},{"key":"R118-3-20210203","doi-asserted-by":"crossref","first-page":"1677","DOI":"10.1056\/NEJM199312023292301","article-title":"Triggering of acute myocardial infarction by heavy physical exertion. Protection against triggering by regular exertion. Determinants of Myocardial Infarction Onset Study Investigators.","volume":"329","author":"Mittleman","year":"1993","journal-title":"N Engl J Med"},{"key":"R119-3-20210203","doi-asserted-by":"crossref","first-page":"1358","DOI":"10.1161\/01.CIR.102.12.1358","article-title":"Physical activity and mortality in older men with diagnosed coronary heart disease.","volume":"102","author":"Wannamethee","year":"2000","journal-title":"Circulation"}],"container-title":["Cardiology in Review"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/CRD.0000000000000032","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,13]],"date-time":"2021-05-13T23:49:17Z","timestamp":1620949757000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00045415-201501000-00003"}},"subtitle":["A Review"],"short-title":[],"issued":{"date-parts":[[2015,1]]},"references-count":108,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015]]}},"URL":"https:\/\/doi.org\/10.1097\/crd.0000000000000032","relation":{},"ISSN":["1061-5377"],"issn-type":[{"value":"1061-5377","type":"print"}],"subject":[],"published":{"date-parts":[[2015,1]]}}}