{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:14:11Z","timestamp":1786119251334,"version":"build-2736575974"},"reference-count":72,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010,1]]},"DOI":"10.1097\/crd.0b013e3181c42f96","type":"journal-article","created":{"date-parts":[[2009,12,10]],"date-time":"2009-12-10T03:30:37Z","timestamp":1260415837000},"page":"12-19","source":"Crossref","is-referenced-by-count":44,"title":["Clinical Applications of Highly Sensitive Troponin Assays"],"prefix":"10.1097","volume":"18","author":[{"given":"Asim A.","family":"Mohammed","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James L.","family":"Januzzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-2-20210203","doi-asserted-by":"crossref","first-page":"1502","DOI":"10.1053\/euhj.2000.2305","article-title":"Myocardial infarction redefined\u2013a consensus document of the Joint European Society of Cardiology\/American College of Cardiology Committee for the redefinition of myocardial infarction.","volume":"21","year":"2000","journal-title":"Eur Heart J"},{"key":"R2-2-20210203","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1161\/01.RES.0000249531.23654.e1","article-title":"Time course of degradation of cardiac troponin I in patients with acute ST-elevation myocardial infarction: the ASSENT-2 troponin substudy.","volume":"99","author":"Madsen","year":"2006","journal-title":"Circ Res"},{"key":"R3-2-20210203","doi-asserted-by":"crossref","first-page":"1760","DOI":"10.1056\/NEJM199212103272415","article-title":"The prognostic value of serum troponin T in unstable angina.","volume":"327","author":"Collinson","year":"1992","journal-title":"N Engl J Med"},{"key":"R4-2-20210203","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1007\/s001340100970","article-title":"Increased troponin in patients with sepsis and septic shock: myocardial necrosis or reversible myocardial depression?","volume":"27","author":"Wu","year":"2001","journal-title":"Intensive Care Med"},{"key":"R5-2-20210203","doi-asserted-by":"crossref","first-page":"2223","DOI":"10.1016\/S0022-2828(95)91587-7","article-title":"Molecular cloning of human cardiac troponin T isoforms: expression in developing and failing heart.","volume":"27","author":"Townsend","year":"1995","journal-title":"J Mol Cell Cardiol"},{"key":"R6-2-20210203","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1161\/01.RES.69.5.1226","article-title":"Troponin T isoform expression in humans. A comparison among normal and failing adult heart, fetal heart, and adult and fetal skeletal muscle.","volume":"69","author":"Anderson","year":"1991","journal-title":"Circ Res"},{"key":"R7-2-20210203","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1161\/01.RES.69.5.1409","article-title":"Troponin I isoform expression in human heart.","volume":"69","author":"Hunkeler","year":"1991","journal-title":"Circ Res"},{"issue":"suppl","key":"R8-2-20210203","first-page":"N30","article-title":"Expression of cardiac troponin T isoforms in skeletal muscle of renal disease patients will not cause false-positive serum results by the second generation cardiac troponin T assay.","volume":"19","author":"Apple","year":"1998","journal-title":"Eur Heart J"},{"key":"R9-2-20210203","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1038\/271031a0","article-title":"Comparison of amino acid sequence of troponin I from different striated muscles.","volume":"271","author":"Wilkinson","year":"1978","journal-title":"Nature"},{"issue":"6","key":"R10-2-20210203","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1093\/clinchem\/44.6.1198","article-title":"Characterization of cardiac troponin subunit release into serum after acute myocardial infarction and comparison of assays for troponin T and I. American Association for Clinical Chemistry Subcommittee on cTnI Standardization.","volume":"44","author":"Wu","year":"1998","journal-title":"Clin Chem"},{"issue":"8","key":"R11-2-20210203","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1093\/clinchem\/43.8.1379","article-title":"Troponin I is released in bloodstream of patients with acute myocardial infarction not in free form but as complex.","volume":"43","author":"Katrukha","year":"1997","journal-title":"Clin Chem"},{"key":"R12-2-20210203","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1161\/01.CIR.96.5.1495","article-title":"Troponin I phosphorylation in the normal and failing adult human heart.","volume":"96","author":"Bodor","year":"1997","journal-title":"Circulation"},{"key":"R13-2-20210203","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1161\/01.CIR.102.11.1221","article-title":"Extensive troponin I and T modification detected in serum from patients with acute myocardial infarction.","volume":"102","author":"Labugger","year":"2000","journal-title":"Circulation"},{"key":"R14-2-20210203","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1016\/S0735-1097(00)00516-7","article-title":"Ingenuous interpretation of elevated blood levels of macromolecular markers of myocardial injury: a recipe for confusion.","volume":"35","author":"Sobel","year":"2000","journal-title":"J Am Coll Cardiol"},{"key":"R15-2-20210203","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1097\/00007611-200194100-00011","article-title":"Plasma elimination of cardiac troponin I in end-stage renal disease.","volume":"94","author":"Ellis","year":"2001","journal-title":"South Med J"},{"key":"R16-2-20210203","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/S0009-8981(01)00547-2","article-title":"Circulating cardiac troponin-T in patients before and after renal transplantation.","volume":"310","author":"Fredericks","year":"2001","journal-title":"Clin Chim Acta"},{"key":"R17-2-20210203","doi-asserted-by":"crossref","first-page":"1568","DOI":"10.1093\/clinchem\/32.8.1568","article-title":"Creatine kinase isoenzymes in extracts of various human skeletal muscles.","volume":"32","author":"Tsung","year":"1986","journal-title":"Clin Chem"},{"key":"R18-2-20210203","doi-asserted-by":"crossref","first-page":"1342","DOI":"10.1056\/NEJM199610313351802","article-title":"Cardiac-specific troponin I levels to predict the risk of mortality in patients with acute coronary syndromes.","volume":"335","author":"Antman","year":"1996","journal-title":"N Engl J Med"},{"key":"R19-2-20210203","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1056\/NEJM199610313351801","article-title":"Cardiac troponin T levels for risk stratification in acute myocardial ischemia. GUSTO IIA Investigators.","volume":"335","author":"Ohman","year":"1996","journal-title":"N Engl J Med"},{"key":"R20-2-20210203","first-page":"e356","article-title":"National Academy of Clinical Biochemistry Laboratory Medicine Practice Guidelines: clinical characteristics and utilization of biochemical markers in acute coronary syndromes.","volume":"115","author":"Morrow","year":"2007","journal-title":"Circulation"},{"key":"R21-2-20210203","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1016\/S0735-1097(00)00804-4","article-title":"Myocardial infarction redefined\u2013a consensus document of the Joint European Society of Cardiology\/American College of Cardiology Committee for the redefinition of myocardial infarction.","volume":"36","author":"Alpert","year":"2000","journal-title":"J Am Coll Cardiol"},{"key":"R22-2-20210203","doi-asserted-by":"crossref","first-page":"2634","DOI":"10.1161\/CIRCULATIONAHA.107.187397","article-title":"Universal definition of myocardial infarction.","volume":"116","author":"Thygesen","year":"2007","journal-title":"Circulation"},{"key":"R23-2-20210203","doi-asserted-by":"crossref","first-page":"1958","DOI":"10.1161\/CIRCULATIONAHA.105.609974","article-title":"Prevalence and determinants of troponin T elevation in the general population.","volume":"113","author":"Wallace","year":"2006","journal-title":"Circulation"},{"key":"R24-2-20210203","doi-asserted-by":"crossref","first-page":"2198","DOI":"10.1373\/clinchem.2005.052886","article-title":"Validation of the 99th percentile cutoff independent of assay imprecision (CV) for cardiac troponin monitoring for ruling out myocardial infarction.","volume":"51","author":"Apple","year":"2005","journal-title":"Clin Chem"},{"key":"R25-2-20210203","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1373\/clinchem.2003.026815","article-title":"Evaluation of imprecision for cardiac troponin assays at low-range concentrations.","volume":"50","author":"Panteghini","year":"2004","journal-title":"Clin Chem"},{"key":"R26-2-20210203","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1373\/clinchem.2007.097865","article-title":"Highly sensitive cardiac troponin T values remain constant after brief exercise-or pharmacologic-induced reversible myocardial ischemia.","volume":"54","author":"Kurz","year":"2008","journal-title":"Clin Chem"},{"key":"R27-2-20210203","doi-asserted-by":"crossref","first-page":"2157","DOI":"10.1373\/clinchem.2006.073163","article-title":"Development and preliminary clinical validation of a high sensitivity assay for cardiac troponin using a capillary flow (single molecule) fluorescence detector.","volume":"52","author":"Wu","year":"2006","journal-title":"Clin Chem"},{"key":"R28-2-20210203","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.1056\/NEJM199905273402103","article-title":"Benefit of abciximab in patients with refractory unstable angina in relation to serum troponin T levels. c7E3 Fab Antiplatelet Therapy in Unstable Refractory Angina (CAPTURE) Study Investigators.","volume":"340","author":"Hamm","year":"1999","journal-title":"N Engl J Med"},{"key":"R29-2-20210203","doi-asserted-by":"crossref","first-page":"2405","DOI":"10.1001\/jama.286.19.2405","article-title":"Ability of minor elevations of troponins I and T to predict benefit from an early invasive strategy in patients with unstable angina and non-ST elevation myocardial infarction: results from a randomized trial.","volume":"286","author":"Morrow","year":"2001","journal-title":"JAMA"},{"key":"R30-2-20210203","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1097\/MCA.0b013e32801682b6","article-title":"Clinical impact of the troponin 99th percentile cut-off and clinical utility of myoglobin measurement in the early management of chest pain patients admitted to the Emergency Cardiology Department.","volume":"18","author":"Amodio","year":"2007","journal-title":"Coron Artery Dis"},{"key":"R31-2-20210203","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1016\/S0002-9149(02)02271-3","article-title":"Clinical performance of three cardiac troponin assays in patients with unstable coronary artery disease (a FRISC II substudy).","volume":"89","author":"Venge","year":"2002","journal-title":"Am J Cardiol"},{"key":"R32-2-20210203","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/S0167-5273(03)00157-8","article-title":"A rapid troponin I assay is not optimal for determination of troponin status and prediction of subsequent cardiac events at suspicion of unstable coronary syndromes.","volume":"93","author":"James","year":"2004","journal-title":"Int J Cardiol"},{"key":"R33-2-20210203","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1373\/clinchem.2008.106500","article-title":"Clinical performance of two highly sensitive cardiac troponin I assays.","volume":"55","author":"Venge","year":"2009","journal-title":"Clin Chem"},{"key":"R34-2-20210203","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1373\/clinchem.2006.076885","article-title":"Long-term health outcomes associated with detectable troponin I concentrations.","volume":"53","author":"Kavsak","year":"2007","journal-title":"Clin Chem"},{"key":"R35-2-20210203","doi-asserted-by":"crossref","first-page":"1907","DOI":"10.1161\/CIRCULATIONAHA.107.708529","article-title":"Persistent cardiac troponin I elevation in stabilized patients after an episode of acute coronary syndrome predicts long-term mortality.","volume":"116","author":"Eggers","year":"2007","journal-title":"Circulation"},{"key":"R36-2-20210203","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1373\/clinchem.2008.114728","article-title":"Role of monitoring changes in sensitive cardiac troponin I assay results for early diagnosis of myocardial infarction and prediction of risk of adverse events.","volume":"55","author":"Apple","year":"2009","journal-title":"Clin Chem"},{"key":"R37-2-20210203","doi-asserted-by":"crossref","first-page":"1832","DOI":"10.1161\/01.CIR.103.14.1832","article-title":"Bedside multimarker testing for risk stratification in chest pain units: the chest pain evaluation by creatine kinase-MB, myoglobin, and troponin I (CHECKMATE) study.","volume":"103","author":"Newby","year":"2001","journal-title":"Circulation"},{"key":"R38-2-20210203","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jacc.2006.02.056","article-title":"Biomarkers in acute cardiac disease: the present and the future.","volume":"48","author":"Jaffe","year":"2006","journal-title":"J Am Coll Cardiol"},{"key":"R39-2-20210203","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1056\/NEJMoa0903515","article-title":"Sensitive troponin I assay in early diagnosis of acute myocardial infarction.","volume":"361","author":"Keller","year":"2009","journal-title":"N Engl J Med"},{"key":"R40-2-20210203","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1056\/NEJMoa0900428","article-title":"Early diagnosis of myocardial infarction with sensitive cardiac troponin assays.","volume":"361","author":"Reichlin","year":"2009","journal-title":"N Engl J Med"},{"key":"R41-2-20210203","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/S0736-4679(01)00456-5","article-title":"Improved identification of acute coronary syndromes with second generation cardiac troponin I assay: utility of 2-hour delta cTnI > or = +0. 02 ng\/mL.","volume":"22","author":"Fesmire","year":"2002","journal-title":"J Emerg Med"},{"key":"R42-2-20210203","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1016\/j.amjcard.2008.11.007","article-title":"Will the universal definition of myocardial infarction criteria result in an overdiagnosis of myocardial infarction?","volume":"103","author":"Eggers","year":"2009","journal-title":"Am J Cardiol"},{"key":"R43-2-20210203","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1016\/j.ahj.2004.04.030","article-title":"Diagnostic value of serial measurement of cardiac markers in patients with chest pain: limited value of adding myoglobin to troponin I for exclusion of myocardial infarction.","volume":"148","author":"Eggers","year":"2004","journal-title":"Am Heart J"},{"key":"R44-2-20210203","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.cca.2007.01.001","article-title":"Effects of contemporary troponin assay sensitivity on the utility of the early markers myoglobin and CKMB isoforms in evaluating patients with possible acute myocardial infarction.","volume":"380","author":"Kavsak","year":"2007","journal-title":"Clin Chim Acta"},{"key":"R45-2-20210203","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1309\/Q9W5HJTT24GQCXXX","article-title":"Earlier detection of myocardial injury in a preliminary evaluation using a new troponin I assay with improved sensitivity.","volume":"128","author":"Melanson","year":"2007","journal-title":"Am J Clin Pathol"},{"key":"R46-2-20210203","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1373\/clinchem.2005.059550","article-title":"Assessing the requirement for the 6-hour interval between specimens in the American Heart Association Classification of Myocardial Infarction in Epidemiology and Clinical Research Studies.","volume":"52","author":"Macrae","year":"2006","journal-title":"Clin Chem"},{"key":"R47-2-20210203","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/S0002-9343(03)00348-6","article-title":"Troponin T levels and risk of 30-day outcomes in patients with the acute coronary syndrome: prospective verification in the GUSTO-IV trial.","volume":"115","author":"James","year":"2003","journal-title":"Am J Med"},{"key":"R48-2-20210203","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/j.ahj.2009.06.011","article-title":"Detection of myocardial injury in patients with unstable angina using a novel nanoparticle cardiac troponin I assay: observations from the PROTECT-TIMI 30 Trial.","volume":"158","author":"Wilson","year":"2009","journal-title":"Am Heart J"},{"key":"R49-2-20210203","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1093\/eurheartj\/ehn504","article-title":"Detection of acute changes in circulating troponin in the setting of transient stress test-induced myocardial ischaemia using an ultrasensitive assay: results from TIMI 35.","volume":"30","author":"Sabatine","year":"2009","journal-title":"Eur Heart J"},{"key":"R50-2-20210203","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1258\/acb.2009.008197","article-title":"Haemodialysis patients longitudinally assessed by highly sensitive cardiac troponin T and commercial cardiac troponin T and cardiac troponin I assays.","volume":"46","author":"Jacobs","year":"2009","journal-title":"Ann Clin Biochem"},{"key":"R51-2-20210203","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1373\/clinchem.2008.106427","article-title":"Reference population and marathon runner sera assessed by highly sensitive cardiac troponin T and commercial cardiac troponin T and I assays.","volume":"55","author":"Mingels","year":"2009","journal-title":"Clin Chem"},{"key":"R52-2-20210203","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1373\/clinchem.2008.107391","article-title":"Short- and long-term biological variation in cardiac troponin I measured with a high-sensitivity assay: implications for clinical practice.","volume":"55","author":"Wu","year":"2009","journal-title":"Clin Chem"},{"key":"R53-2-20210203","doi-asserted-by":"crossref","first-page":"301","DOI":"10.2165\/00002018-200225050-00001","article-title":"Predicting cancer therapy-induced cardiotoxicity: the role of troponins and other markers.","volume":"25","author":"Sparano","year":"2002","journal-title":"Drug Saf"},{"key":"R54-2-20210203","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1309\/AJCPB66LRIIVMQDR","article-title":"Biochemical markers for prediction of chemotherapy-induced cardiotoxicity: systematic review of the literature and recommendations for use.","volume":"130","author":"Dolci","year":"2008","journal-title":"Am J Clin Pathol"},{"key":"R55-2-20210203","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1373\/clinchem.2007.101683","article-title":"Value of cardiac troponin I cutoff concentrations below the 99th percentile for clinical decision-making.","volume":"55","author":"Eggers","year":"2009","journal-title":"Clin Chem"},{"key":"R56-2-20210203","doi-asserted-by":"crossref","first-page":"2086","DOI":"10.1373\/clinchem.2007.095679","article-title":"National Academy of Clinical Biochemistry laboratory medicine practice guidelines: use of cardiac troponin and B-type natriuretic peptide or N-terminal proB-type natriuretic peptide for etiologies other than acute coronary syndromes and heart failure.","volume":"53","author":"Wu","year":"2007","journal-title":"Clin Chem"},{"key":"R57-2-20210203","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1373\/clinchem.2008.108837","article-title":"Specificity of a high-sensitivity cardiac troponin I assay using single-molecule-counting technology.","volume":"55","author":"Wu","year":"2009","journal-title":"Clin Chem"},{"key":"R58-2-20210203","doi-asserted-by":"crossref","first-page":"1598","DOI":"10.1093\/eurheartj\/ehm161","article-title":"Guidelines for the diagnosis and treatment of non-ST-segment elevation acute coronary syndromes.","volume":"28","author":"Bassand","year":"2007","journal-title":"Eur Heart J"},{"key":"R59-2-20210203","doi-asserted-by":"crossref","first-page":"2004","DOI":"10.1016\/S0735-1097(03)00421-2","article-title":"Troponin as a risk factor for mortality in critically ill patients without acute coronary syndromes.","volume":"41","author":"Ammann","year":"2003","journal-title":"J Am Coll Cardiol"},{"key":"R60-2-20210203","doi-asserted-by":"crossref","first-page":"2432","DOI":"10.1161\/01.CIR.0000127882.58426.7A","article-title":"Optimal noninvasive assessment of left ventricular filling pressures: a comparison of tissue doppler echocardiography and B-type natriuretic peptide in patients with pulmonary artery catheters.","volume":"109","author":"Dokainish","year":"2004","journal-title":"Circulation"},{"key":"R61-2-20210203","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1161\/01.CIR.0000134279.79571.73","article-title":"Anemia and its relationship to clinical outcome in heart failure.","volume":"110","author":"Anand","year":"2004","journal-title":"Circulation"},{"key":"R62-2-20210203","doi-asserted-by":"crossref","first-page":"1755","DOI":"10.1016\/j.jacc.2006.05.075","article-title":"A model for troponin I as a quantitative predictor of in-hospital mortality.","volume":"48","author":"Waxman","year":"2006","journal-title":"J Am Coll Cardiol"},{"key":"R63-2-20210203","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1046\/j.1445-5994.2002.00270.x","article-title":"Causes of elevated troponin I with a normal coronary angiogram.","volume":"32","author":"Bakshi","year":"2002","journal-title":"Intern Med J"},{"key":"R64-2-20210203","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/S0002-8703(96)90359-2","article-title":"Improved detection of cardiac confusion with cardiac troponin I.","volume":"131","author":"Adams","year":"1996","journal-title":"Am Heart J"},{"key":"R66-2-20210203","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1016\/S1053-2498(00)00120-0","article-title":"Cardiac troponin I as diagnostic and prognostic marker in severe heart failure.","volume":"19","author":"La Vecchia","year":"2000","journal-title":"J Heart Lung Transplant"},{"key":"R67-2-20210203","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/S0735-1097(98)00257-5","article-title":"Elevated serum concentrations of cardiac troponin T in acute allograft rejection after human heart transplantation.","volume":"32","author":"Dengler","year":"1998","journal-title":"J Am Coll Cardiol"},{"key":"R68-2-20210203","doi-asserted-by":"crossref","first-page":"1560","DOI":"10.1373\/clinchem.2004.031468","article-title":"Cardiac troponin T for prediction of short- and long-term morbidity and mortality after elective open heart surgery.","volume":"50","author":"Lehrke","year":"2004","journal-title":"Clin Chem"},{"key":"R69-2-20210203","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1161\/01.STR.0000114874.96688.54","article-title":"Predictors of neurocardiogenic injury after subarachnoid hemorrhage.","volume":"35","author":"Tung","year":"2004","journal-title":"Stroke"},{"key":"R70-2-20210203","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1161\/01.STR.31.5.1136","article-title":"Regional myocardial perfusion after experimental subarachnoid hemorrhage editorial comment.","volume":"31","author":"Zaroff","year":"2000","journal-title":"Stroke"},{"key":"R71-2-20210203","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1001\/archinte.166.10.1081","article-title":"Cost-effectiveness of B-type natriuretic peptide testing in patients with acute dyspnea.","volume":"166","author":"Mueller","year":"2006","journal-title":"Arch Intern Med"},{"key":"R72-2-20210203","doi-asserted-by":"crossref","first-page":"786","DOI":"10.7326\/0003-4819-142-9-200505030-00015","article-title":"Narrative review: alternative causes for elevated cardiac troponin levels when acute coronary syndromes are excluded.","volume":"142","author":"Jeremias","year":"2005","journal-title":"Ann Intern Med"},{"key":"R73-2-20210203","doi-asserted-by":"crossref","first-page":"2065","DOI":"10.1016\/S0735-1097(02)02608-6","article-title":"Cardiac troponins in renal insufficiency: review and clinical implications.","volume":"40","author":"Freda","year":"2002","journal-title":"J Am Coll Cardiol"}],"container-title":["Cardiology in Review"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.1097\/CRD.0b013e3181c42f96","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T18:06:05Z","timestamp":1786039565000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00045415-201001000-00002"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,1]]},"references-count":72,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010]]}},"URL":"https:\/\/doi.org\/10.1097\/crd.0b013e3181c42f96","relation":{},"ISSN":["1061-5377"],"issn-type":[{"value":"1061-5377","type":"print"}],"subject":[],"published":{"date-parts":[[2010,1]]}}}