{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,17]],"date-time":"2025-06-17T04:07:46Z","timestamp":1750133266538,"version":"3.41.0"},"reference-count":8,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:title>Abstract:<\/jats:title>\n          <jats:p>Chondrodermatitis nodularis helicis is an inflammatory condition affecting the helix or antihelix of the ear. It is commonly described as a solitary, painful, ulcerated nodule affecting the cartilage or skin because of continuous pressure, trauma, sun exposure, or ischemic changes. In this case report, we present a rare variant of chondrodermatitis, named chondrodermatitis nodularis nasi, which affects the skin and cartilage of the nose. Clinical resemblance to neoplasms of the skin such as squamous cell carcinoma and basal cell carcinoma requires that a biopsy be performed for definitive diagnosis. On histopathological examination, chondrodermatitis presents as a central ulcer bordered by epidermal hyperplasia, hypergranulosis, hyperkeratosis, and parakeratosis with fibrin deposits in the papillary dermis admixed with sparse inflammatory cells. Included in this case report is a discussion of the clinical and histopathology of chondrodermatitis nodularis nasi. With increased frequency of diagnosing this rare variant, better management and treatments can be explored.<\/jats:p>","DOI":"10.1097\/dad.0000000000001981","type":"journal-article","created":{"date-parts":[[2021,6,16]],"date-time":"2021-06-16T15:14:33Z","timestamp":1623856473000},"page":"115-117","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Chondrodermatitis Nodularis Nasi: A Case Report of a Rare Variant of Chondrodermatitis Nodularis Helicis"],"prefix":"10.1097","volume":"44","author":[{"given":"Arjun","family":"Bal","sequence":"first","affiliation":[{"name":"Arizona College of Osteopathic Medicine - Midwestern University, Glendale, AZ;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zaina","family":"Rashid","sequence":"additional","affiliation":[{"name":"La Peau Dermatology Mesa, AZ; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. Nicholas","family":"Shamma","sequence":"additional","affiliation":[{"name":"American Dermatopathology Laboratory Centerville, OH."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","published-online":{"date-parts":[[2021,6,15]]},"reference":[{"key":"R1-20250616","first-page":"e2367","article-title":"Review of the etiopathogenesis and management options of chondrodermatitis nodularis chronica helicis","volume":"10","author":"Salah","year":"2018","journal-title":"Cureus."},{"key":"R2-20250616","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1001\/archderm.1953.01540090003001","article-title":"Chondrodermatitis nodularis chronica helicis; report of ninety-four cases and survey of literature, with emphasis upon pathogenesis and treatment","volume":"68","author":"Newcomer","year":"1953","journal-title":"AMA Arch Derm Syphilol."},{"key":"R3-20250616","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1007\/BF01822914","article-title":"Kn\u00f6tchenf\u00f6rmige Erkrankung am Helix (Chondrodermatitis nodularis chronica helicis)","volume":"121","author":"Winkler","year":"1916","journal-title":"Arch Dermatol Syph."},{"key":"R5-20250616","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1136\/jcp.12.2.179","article-title":"On the histopathology of chondrodermatitis nodularis helicis chronica","volume":"12","author":"Calnan","year":"1959","journal-title":"J Clin Pathol."},{"key":"R6-20250616","doi-asserted-by":"crossref","DOI":"10.1111\/dth.12434","article-title":"Chondrodermatitis nodularis helicis: a review of current therapies","volume":"30","author":"Shah","year":"2017","journal-title":"Dermatol Ther."},{"key":"R7-20250616","first-page":"188","article-title":"Chondrodermatitis nodularis nasalis: a new variant of chondrodermatitis nodularis helicis poster 107 fellow","volume":"41","author":"Motaparthi","year":"2014","journal-title":"J Cutan Pathol."},{"key":"R8-20250616","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1097\/DSS.0000000000001515","article-title":"Chondrodermatitis nodularis chronica helicis of the right nasal vestibule","volume":"44","author":"Darragh","year":"2018","journal-title":"Dermatol Surg."},{"key":"R9-20250616","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1111\/cup.13786","article-title":"Chondrodermatitis nodularis nasi","volume":"47","author":"Kasitinon","year":"2020","journal-title":"J Cutan Pathol."}],"container-title":["The American Journal of Dermatopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/DAD.0000000000001981","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,16]],"date-time":"2025-06-16T19:03:34Z","timestamp":1750100614000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.1097\/DAD.0000000000001981"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,15]]},"references-count":8,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.1097\/dad.0000000000001981","relation":{},"ISSN":["0193-1091"],"issn-type":[{"type":"print","value":"0193-1091"}],"subject":[],"published":{"date-parts":[[2021,6,15]]}}}