{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:33:27Z","timestamp":1786120407806,"version":"build-2736575974"},"reference-count":100,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,3]]},"DOI":"10.1097\/dcr.0b013e318239d1e4","type":"journal-article","created":{"date-parts":[[2012,2,8]],"date-time":"2012-02-08T07:23:48Z","timestamp":1328685828000},"page":"351-358","source":"Crossref","is-referenced-by-count":141,"title":["A Systematic Review of the Anal Fistula Plug for Patients With Crohn's and Non-Crohn's Related Fistula-in-Ano"],"prefix":"10.1097","volume":"55","author":[{"given":"J. M.","family":"O'Riordan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Datta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Johnston","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N. N.","family":"Baxter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-18-20210119","first-page":"139","article-title":"Anorectal sepsis and fistula-in-ano.","volume":"17","author":"Juviler","year":"2008","journal-title":"Surg Technol Int"},{"key":"R2-18-20210119","first-page":"CD006319","article-title":"Surgical intervention for anorectal fistula.","volume":"5","author":"Jacob","year":"2010","journal-title":"Cochrane Database Syst Rev"},{"key":"R3-18-20210119","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1111\/j.1463-1318.2009.01806.x","article-title":"Risk factors for recurrence and incontinence after anal fistula surgery.","volume":"12","author":"Jordan","year":"2010","journal-title":"Colorectal Dis"},{"key":"R4-18-20210119","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1002\/bjs.6608","article-title":"Outcome of surgical treatment for fistula in ano in Crohns disease.","volume":"96","author":"Van Koperen","year":"2009","journal-title":"Br J Surg"},{"key":"R5-18-20210119","doi-asserted-by":"crossref","first-page":"1652","DOI":"10.1007\/DCR.0b013e3181f2e9cd","article-title":"Sphincter-preserving fistula management: what patients want.","volume":"53","author":"Ellis","year":"2010","journal-title":"Dis Colon Rectum"},{"key":"R6-18-20210119","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/S0002-9610(99)00180-4","article-title":"Endoanal advancement flap repair for complex anorectal fistulas.","volume":"178","author":"Hyman","year":"1999","journal-title":"Am J Surg"},{"key":"R7-18-20210119","first-page":"1616","article-title":"Zmora O, et al..","volume":"45","author":"Mizrahi","year":"2002","journal-title":"Endorectal advancement flap: are there predictors of failure Dis Colon Rectum"},{"key":"R8-18-20210119","doi-asserted-by":"crossref","first-page":"1680","DOI":"10.1046\/j.1365-2168.2000.01582.x","article-title":"Endorectal flap advancement repair and fistulectomy for high trans-sphincteric and suprasphincteric fistulas.","volume":"87","author":"Ortiz","year":"2000","journal-title":"Br J Surg"},{"key":"R9-18-20210119","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1007\/BF02235039","article-title":"Transanal advancement flap repair of transsphincteric fistulas.","volume":"42","author":"Schouten","year":"1999","journal-title":"Dis Colon Rectum"},{"key":"R10-18-20210119","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1007\/BF02050009","article-title":"Autologous fibrin glue in the treatment of rectovaginal and complex fistulas.","volume":"36","author":"Abel","year":"1993","journal-title":"Dis Colon Rectum"},{"key":"R11-18-20210119","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1007\/BF02237355","article-title":". Repair of fistulas-in-ano using fibrin adhesive: long-term follow-up.","volume":"43","author":"Cintron","year":"2000","journal-title":"Dis Colon Rectum"},{"key":"R12-18-20210119","doi-asserted-by":"crossref","first-page":"1608","DOI":"10.1007\/s10350-004-7247-0","article-title":"A randomized, controlled trial of fibrin glue vs conventional treatment for anal fistula.","volume":"45","author":"Lindsey","year":"2002","journal-title":"Dis Colon Rectum"},{"key":"R13-18-20210119","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1007\/s10350-004-0898-z","article-title":". Treatment of fistulas-in-ano with fibrin sealant in combination with intra-adhesive antibiotics andor surgical closure of the internal fistula opening.","volume":"48","author":"Singer","year":"2005","journal-title":"Dis Colon Rectum"},{"key":"R14-18-20210119","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1007\/s10151-005-0204-7","article-title":"Fibrin glue for fistula-in-ano: the evidence reviewed.","volume":"9","author":"Swinscoe","year":"2005","journal-title":"Tech Coloproctol"},{"key":"R15-18-20210119","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1007\/BF02070710","article-title":"Cutting seton for anal fistulas: high risk of minor control defects.","volume":"40","author":"Hamalainen","year":"1997","journal-title":"Dis Colon Rectum"},{"key":"R16-18-20210119","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1046\/j.1365-2168.1998.02877.x","article-title":"Cutting seton versus two-stage seton fistulotomy in the surgical management of high anal fistula.","volume":"85","author":"Garcia-Aguilar","year":"1998","journal-title":"Br J Surg"},{"key":"R17-18-20210119","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1007\/BF02234574","article-title":"The cutting seton: an experience at King Faisal Specialist Hospital.","volume":"44","author":"Isbister","year":"2001","journal-title":"Dis Colon Rectum"},{"key":"R18-18-20210119","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1111\/j.1463-1318.2008.01713.x","article-title":"Incontinence rates after cutting seton treatment for anal fistula.","volume":"11","author":"Ritchie","year":"2009","journal-title":"Colorectal Dis"},{"key":"R19-18-20210119","first-page":"581","article-title":"Total anal sphincter saving technique for fistula-in-ano: the ligation of intersphincteric fistula tract.","volume":"90","author":"Rojanasakul","year":"2007","journal-title":"J Med Assoc Thai"},{"key":"R20-18-20210119","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1007\/DCR.0b013e3181bb869f","article-title":"Ligation of the intersphincteric fistula tract: an effective new technique for complex fistulas.","volume":"53","author":"Bleier","year":"2010","journal-title":"Dis Colon Rectum"},{"key":"R21-18-20210119","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1007\/DCR.0b013e3181c160c4","article-title":"Ligation of the intersphincteric fistula tract (LIFT): a sphincter-saving technique for fistula-in-ano.","volume":"53","author":"Shanwani","year":"2010","journal-title":"Dis Colon Rectum"},{"key":"R22-18-20210119","doi-asserted-by":"crossref","first-page":"1817","DOI":"10.1007\/s10350-006-0755-3","article-title":"Efficacy of anal fistula plug in closure of cryptoglandular fistulas: long-term follow-up.","volume":"49","author":"Champagne","year":"2006","journal-title":"Dis Colon Rectum"},{"key":"R23-18-20210119","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/S1084952102000940","article-title":"The extracellular matrix as a scaffold for tissue reconstruction.","volume":"13","author":"Badylak","year":"2002","journal-title":"Semin Cell Dev Biol"},{"key":"R24-18-20210119","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1007\/DCR.0b013e31819c96ac","article-title":"Anal fistula plug: initial experience and outcomes.","volume":"52","author":"Safar","year":"2009","journal-title":"Dis Colon Rectum"},{"key":"R25-18-20210119","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1007\/DCR.0b013e318206043e","article-title":". The anal fistula plug treatment compared with the mucosal advancement flap for cryptoglandular high transsphincteric perianal fistula: a double-blinded multicenter randomized trial.","volume":"54","author":"Van Koperen","year":"2011","journal-title":"Dis Colon Rectum"},{"key":"R26-18-20210119","first-page":"4369","article-title":"Anal fistula treated with collagen plug in Danish.","volume":"169","author":"Rasmussen","year":"2007","journal-title":"Ugeskr Laeger"},{"key":"R27-18-20210119","first-page":"157","article-title":"Initial experience with collagen plug for the treatment of complex anal fistula in Hebrew.","volume":"148","author":"Itah","year":"2009","journal-title":"Harefuah"},{"key":"R28-18-20210119","first-page":"46","article-title":". Conservative anal fistula treatment with collagenic plug and human fibrin sealant: preliminary results.","volume":"30","author":"Gubitosi","year":"2009","journal-title":"G Chir"},{"key":"R29-18-20210119","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1002\/bjs.6772","article-title":"Randomized clinical trial of anal fistula plug versus endorectal advancement flap for the treatment of high cryptoglandular fistula in ano.","volume":"96","author":"Garg","year":"2009","journal-title":"Br J Surg"},{"key":"R30-18-20210119","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1007\/DCR.0b013e3181e1a49e","article-title":"Focus on sphincter-saving procedures for fistula-in-ano.","volume":"53","author":"Milito","year":"2010","journal-title":"Dis Colon Rectum"},{"key":"R31-18-20210119","doi-asserted-by":"crossref","first-page":"7143","DOI":"10.3748\/wjg.14.7143","article-title":"Acellular extracellular matrix anal fistula plug: results in high fistula-in-ano awaited.","volume":"14","author":"Garg","year":"2008","journal-title":"World J Gastroenterol"},{"key":"R32-18-20210119","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/1750-1164-3-12","article-title":". Fibrin glue in the treatment of anal fistula: a systematic review.","volume":"3","author":"Cirocchi","year":"2009","journal-title":"Ann Surg Innov Res"},{"key":"R33-18-20210119","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1111\/j.1463-1318.2008.01483.x","article-title":"Surgical management of anal fistulae: a systematic review.","volume":"10","author":"Malik","year":"2008","journal-title":"Colorectal Dis"},{"key":"R34-18-20210119","doi-asserted-by":"crossref","first-page":"4263","DOI":"10.3748\/wjg.15.4263","article-title":"Emerging treatments for complex perianal fistula in Crohns disease.","volume":"15","author":"Taxonera","year":"2009","journal-title":"World J Gastroenterol"},{"key":"R35-18-20210119","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.suc.2009.09.004","article-title":"Anorectal Crohns disease.","volume":"90","author":"Lewis","year":"2010","journal-title":"Surg Clin North Am"},{"key":"R36-18-20210119","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1111\/j.1463-1318.2009.01933.x","article-title":"The efficacy of the anal fistula plug in fistula-in-ano: a systematic review.","volume":"12","author":"Garg","year":"2010","journal-title":"Colorectal Dis"},{"key":"R37-18-20210119","first-page":"1105","article-title":"Who benefits from the anal fistula plug Dis Colon Rectum.","volume":"53","author":"Christoforidis","year":"2010","journal-title":""},{"key":"R38-18-20210119","doi-asserted-by":"crossref","first-page":"3277","DOI":"10.3748\/wjg.v17.i28.3277","article-title":"Idiopathic fistula-in-ano.","volume":"17","author":"Shawki","year":"2011","journal-title":"World J Gastroenterol"},{"key":"R39-18-20210119","doi-asserted-by":"crossref","first-page":"e203","DOI":"10.1016\/j.jviscsurg.2010.07.007","article-title":"Cryptoglandular anal fistula.","volume":"147","author":"De Parades","year":"2010","journal-title":"J Visc Surg"},{"key":"R40-18-20210119","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.cursur.2006.07.005","article-title":"Bioprosthetic plugs for complex anal fistulas: an early experience.","volume":"64","author":"Ellis","year":"2007","journal-title":"J Surg Educ"},{"key":"R41-18-20210119","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1007\/s10151-009-0470-x","article-title":"Innovative technique for the closure of rectovaginal fistula using Surgisis mesh.","volume":"13","author":"Schwandner","year":"2009","journal-title":"Tech Coloproctol"},{"key":"R42-18-20210119","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1007\/s00384-007-0398-4","article-title":"Initial experience on efficacy in closure of cryptoglandular and Crohns transsphincteric fistulas by use of the anal fistula plug.","volume":"23","author":"Schwandner","year":"2008","journal-title":"Int J Colorectal Dis"},{"key":"R43-18-20210119","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1007\/s10350-005-0288-1","article-title":"Efficacy of anal fistula plug versus fibrin glue in closure of anorectal fistulas.","volume":"49","author":"Johnson","year":"2006","journal-title":"Dis Colon Rectum"},{"key":"R44-18-20210119","doi-asserted-by":"crossref","first-page":"1482","DOI":"10.1007\/s10350-008-9374-5","article-title":"Treatment of complex anal fistulas with the collagen fistula plug.","volume":"51","author":"Christoforidis","year":"2008","journal-title":"Dis Colon Rectum"},{"issue":"suppl s2","key":"R45-18-20210119","first-page":"62","article-title":"Anal fistula plug in high and complicated fistula-in-ano: a Saudi experience.","volume":"10","author":"Zubaidi","year":"2008","journal-title":"Colorectal Dis"},{"key":"R46-18-20210119","first-page":"725","article-title":". Anal fistula plug: initial experience and outcomes.","volume":"50","author":"Safar","year":"2007","journal-title":"Dis Colon Rectum"},{"key":"R47-18-20210119","first-page":"749","article-title":". Anal fistula plug (AFP) for the treatment of fistula-in-ano.","volume":"50","author":"Abbas","year":"2007","journal-title":"Dis Colon Rectum"},{"key":"R48-18-20210119","first-page":"636","article-title":"Long term results with the bioprosthetic anal fistula plug (AFP).","volume":"51","author":"Rostos","year":"2008","journal-title":"Dis Colon Rectum"},{"key":"R49-18-20210119","first-page":"638","article-title":"Treatment of transphincteric anal fistulas by endorectal advancement flap or anal fistula plug: a comparative study.","volume":"51","author":"Christoforidis","year":"2008","journal-title":"Dis Colon Rectum"},{"key":"R50-18-20210119","first-page":"A862","article-title":"Plugging away at the anal fistula: an exercise in futility Gastroenterology.","volume":"134","author":"El-Gazzaz","year":"2008","journal-title":""},{"key":"R51-18-20210119","first-page":"842","article-title":". Fistula tract length predicts success with the Surgisis fistula plug.","volume":"52","author":"McGee","year":"2009","journal-title":"Dis Colon Rectum"},{"issue":"suppl s2","key":"R52-18-20210119","first-page":"1","article-title":"Anal fistula plug for closure of difficult anorectal fistula; results of a prospective randomized study.","volume":"10","author":"Ciga","year":"2008","journal-title":"Colorectal Dis"},{"issue":"suppl s3","key":"R53-18-20210119","first-page":"7","article-title":"Zawadzki. The results of the anal fistula plug for high transphincteric fistula.","volume":"9","author":"Bohe","year":"2007","journal-title":"Colorectal Dis"},{"issue":"suppl s3","key":"R54-18-20210119","first-page":"59","article-title":"Anal fistula plug for closure of difficult perianal fistulas-a prospective study.","volume":"9","author":"Van Koperen","year":"2007","journal-title":"Colorectal Dis"},{"issue":"suppl s3","key":"R55-18-20210119","first-page":"59","article-title":". Efficacy of anal fistula plug in closure of recurrent anorectal fistulae.","volume":"9","author":"Thekkinkattil","year":"2007","journal-title":"Colorectal Dis"},{"issue":"suppl s3","key":"R56-18-20210119","first-page":"58","article-title":"Therapy of the complex transsphincteric fistula with a fistula plug: first results.","volume":"9","author":"Schwandner","year":"2007","journal-title":"Colorectal Dis"},{"issue":"suppl s3","key":"R57-18-20210119","first-page":"51","article-title":"Repair of high anal fistula with a bioprosthetic collagen plug.","volume":"9","author":"Christoforidis","year":"2007","journal-title":"Colorectal Dis"},{"issue":"suppl s1","key":"R58-18-20210119","first-page":"8","article-title":". Anal fistula plug: initial experience and outcomes.","volume":"9","author":"Safar","year":"2007","journal-title":"Colorectal Dis"},{"key":"R59-18-20210119","doi-asserted-by":"crossref","first-page":"4791","DOI":"10.3748\/wjg.14.4791","article-title":"An anorectal fistula treatment with acellular extracellular matrix: a new technique.","volume":"14","author":"Song","year":"2008","journal-title":"World J Gastroenterol"},{"key":"R60-18-20210119","doi-asserted-by":"crossref","first-page":"1877","DOI":"10.1007\/DCR.0b013e3181b55560","article-title":"Assessment of the efficacy of the rectovaginal button fistula plug for the treatment of ileal pouch-vaginal and rectovaginal fistulas.","volume":"52","author":"Gonsalves","year":"2009","journal-title":"Dis Colon Rectum"},{"key":"R61-18-20210119","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1007\/s10350-008-9339-8","article-title":"Outcomes after repair of rectovaginal fistulas using bioprosthetics.","volume":"51","author":"Ellis","year":"2008","journal-title":"Dis Colon Rectum"},{"issue":"suppl s1","key":"R62-18-20210119","first-page":"41","article-title":"Assessment of the efficacy of the Surgisis Biodesign rectovaginal fistula plug (button fistula plug) for the treatment of ileal-pouch vaginal and recto-vaginal fistulas.","volume":"11","author":"Gonsalves","year":"2009","journal-title":"Colorectal Dis"},{"key":"R63-18-20210119","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1007\/s00384-010-0957-y","article-title":". Anal fistula plug is a valid alternative option for the treatment of complex anal fistula in the long term.","volume":"25","author":"Lenisa","year":"2010","journal-title":"Int J Colorectal Dis"},{"key":"R64-18-20210119","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.1007\/s10350-006-0695-y","article-title":"Efficacy of anal fistula plug in closure of Crohns anorectal fistulas.","volume":"49","author":"OConnor","year":"2006","journal-title":"Dis Colon Rectum"},{"key":"R65-18-20210119","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1007\/DCR.0b013e3181d43b7d","article-title":"Long-term outcomes with the use of bioprosthetic plugs for the management of complex anal fistulas.","volume":"53","author":"Ellis","year":"2010","journal-title":"Dis Colon Rectum"},{"key":"R66-18-20210119","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1007\/s10350-007-9191-2","article-title":"Collagen fistula plug for the treatment of anal fistulas.","volume":"51","author":"Ky","year":"2008","journal-title":"Dis Colon Rectum"},{"issue":"suppl s2","key":"R67-18-20210119","first-page":"52","article-title":". Long term results in the treatment of anal fistulae with anal fistula plug (Surgisis AFP).","volume":"10","author":"Espin Basany","year":"2008","journal-title":"Colorectal Dis"},{"issue":"suppl s2","key":"R68-18-20210119","first-page":"15","article-title":". The long term efficacy of the anal plug procedure (AFP) for complex cryptoglandular fistula.","volume":"11","author":"Lenisa","year":"2009","journal-title":"Colorectal Dis"},{"key":"R69-18-20210119","first-page":"725","article-title":"Short-term results in the treatment of anal fistulas with Surgisis AFP.","volume":"50","author":"Ky","year":"2007","journal-title":"Dis Colon Rectum"},{"key":"R70-18-20210119","first-page":"779","article-title":"Follow-up of collagen plug for anorectal fistulas.","volume":"52","author":"Khaitov","year":"2009","journal-title":"Dis Colon Rectum"},{"issue":"suppl s3","key":"R71-18-20210119","first-page":"54","article-title":"Obliterative treatment for cryptoglandular fistula with anal plug.","volume":"9","author":"Lenisa","year":"2007","journal-title":"Does it work in Europe Colorectal Dis"},{"key":"R72-18-20210119","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1111\/j.1463-1318.2008.01627.x","article-title":". Efficacy of the anal fistula plug in complex anorectal fistulae.","volume":"11","author":"Thekkinkattil","year":"2009","journal-title":"Colorectal Dis"},{"key":"R73-18-20210119","doi-asserted-by":"crossref","first-page":"2022","DOI":"10.1007\/DCR.0b013e3181b72378","article-title":"Outcomes after fistulotomy: results of a prospective, multicenter regional study.","volume":"52","author":"Hyman","year":"2009","journal-title":"Dis Colon Rectum"},{"key":"R74-18-20210119","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1007\/DCR.0b013e3181b72378","article-title":"Outcomes after fistulotomy: results of a prospective, multicenter regional study.","volume":"52","author":"Hyman","year":"2009","journal-title":"Dis Colon Rectum"},{"issue":"suppl s3","key":"R75-18-20210119","first-page":"49","article-title":"Anal fistula plug versus cutting seton for the treatment of transphincteric anal fistula.","volume":"12","author":"Herman","year":"2010","journal-title":"Colorectal Dis"},{"issue":"suppl s1","key":"R76-18-20210119","first-page":"1","article-title":"Anal canal pressures are reduced following insertion of anal fistula plug.","volume":"12","author":"Schizas","year":"2010","journal-title":"Colorectal Dis"},{"key":"R77-18-20210119","doi-asserted-by":"crossref","first-page":"1713","DOI":"10.1007\/DCR.0b013e3181f569f8","article-title":"The anal fistula plug as an adjunct to transanal advancement flap repair.","volume":"5312","author":"Mitalas","year":"2010","journal-title":"Dis Colon Rectum"},{"key":"R78-18-20210119","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/j.gcb.2009.06.021","article-title":"Treatment of fistula-in-ano with the Surgisis() AFP(TM) anal fistula plug.","volume":"34","author":"Lupinacci","year":"2010","journal-title":"Gastroenterol Clin Biol"},{"key":"R79-18-20210119","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/j.amjsurg.2010.01.007","article-title":"Outcomes of anal fistula surgery in patients with inflammatory bowel disease.","volume":"199","author":"Chung","year":"2010","journal-title":"Am J Surg"},{"key":"R80-18-20210119","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1007\/DCR.0b013e3181d972a9","article-title":"Tract length predicts successful closure with anal fistula plug in cryptoglandular fistulas.","volume":"53","author":"McGee","year":"2010","journal-title":"Dis Colon Rectum"},{"key":"R81-18-20210119","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.surg.2009.05.018","article-title":"To plug or not to plug: a cost-effectiveness analysis for complex anal fistula.","volume":"147","author":"Adamina","year":"2010","journal-title":"Surgery"},{"key":"R82-18-20210119","first-page":"575","article-title":"The anal fistula plug in simple and complex fistula-in-ano: a western New York experience.","volume":"53","author":"Anyadike","year":"2010","journal-title":"Dis Colon Rectum"},{"key":"R83-18-20210119","first-page":"1584","article-title":"Anal fistula plug in high fistula-in-ano: an early Saudi experience.","volume":"52","author":"Zubaidi","year":"2009","journal-title":"Dis Colon Rectum"},{"key":"R84-18-20210119","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1177\/1553350609338041","article-title":"Preliminary results on efficacy in closure of transsphincteric and rectovaginal fistulas associated with Crohns disease using new biomaterials.","volume":"16","author":"Schwandner","year":"2009","journal-title":"Surg Innov"},{"key":"R85-18-20210119","doi-asserted-by":"crossref","first-page":"1578","DOI":"10.1007\/DCR.0b013e3181a8fbb7","article-title":"Surgical treatment of complex anal fistulas with the anal fistula plug: a prospective, multicenter study.","volume":"52","author":"Schwandner","year":"2009","journal-title":"Dis Colon Rectum"},{"key":"R86-18-20210119","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1002\/bjs.6613","article-title":"Randomized clinical trial of anal fistula plug versus endorectal advancement flap for the treatment of high cryptoglandular fistula in ano.","volume":"96","author":"Ortiz","year":"2009","journal-title":"Br J Surg"},{"key":"R87-18-20210119","first-page":"692","article-title":"Treatment of transsphincteric anal fistulas: are fistula plugs an acceptable alternative Dis Colon Rectum.","volume":"52","author":"Wang","year":"2009","journal-title":""},{"key":"R88-18-20210119","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1016\/j.amjsurg.2008.12.013","article-title":". Anal fistula plug and fibrin glue versus conventional treatment in repair of complex anal fistulas.","volume":"197","author":"Chung","year":"2009","journal-title":"Am J Surg"},{"key":"R89-18-20210119","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1007\/DCR.0b013e31819756ac","article-title":"Treatment of transsphincteric anal fistulas by endorectal advancement flap or collagen fistula plug: a comparative study.","volume":"52","author":"Christoforidis","year":"2009","journal-title":"Dis Colon Rectum"},{"key":"R90-18-20210119","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1007\/s00268-008-9504-1","article-title":"Early experience with the bioabsorbable anal fistula plug.","volume":"32","author":"Lawes","year":"2008","journal-title":"World J Surg"},{"key":"R91-18-20210119","first-page":"692","article-title":"Success rate of closure of high transphincteric fistulas using anal fistula plug.","volume":"51","author":"Starck","year":"2008","journal-title":"Dis Colon Rectum"},{"key":"R92-18-20210119","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1111\/j.1463-1318.2008.01632.x","article-title":"To determine the efficacy of anal fistula plug in the treatment of high fistula-in-ano: an initial experience.","volume":"11","author":"Garg","year":"2009","journal-title":"Colorectal Dis"},{"key":"R93-18-20210119","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1111\/j.1463-1318.2009.01802.x","article-title":"A retrospective review of chronic anal fistulae treated by anal fistulae plug.","volume":"12","author":"El-Gazzaz","year":"2010","journal-title":"Colorectal Dis"},{"key":"R94-18-20210119","first-page":"8","article-title":"Puerto Rico experience with plugs in the treatment of anal fistulas.","volume":"100","author":"Echenique","year":"2008","journal-title":"Bol Asoc Med P R"},{"key":"R95-18-20210119","doi-asserted-by":"crossref","first-page":"2168","DOI":"10.1007\/s10350-007-0298-2","article-title":"Anal fistula plug for closure of difficult anorectal fistula: a prospective study.","volume":"50","author":"Van Koperen","year":"2007","journal-title":"Dis Colon Rectum"},{"key":"R96-18-20210119","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1007\/s10350-003-0076-8","article-title":"Fibrin glue treatment of complex anal fistulas has low success rate.","volume":"47","author":"Loungnarath","year":"2004","journal-title":"Dis Colon Rectum"},{"key":"R97-18-20210119","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1007\/DCR.0b013e3181ce8b01","article-title":"Endorectal advancement flap for cryptoglandular or Crohns fistula-in-ano.","volume":"53","author":"Soltani","year":"2010","journal-title":"Dis Colon Rectum"},{"key":"R98-18-20210119","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1111\/j.1445-2197.2010.05278.x","article-title":". Plugs unplugged. Anal fistula plug: the Concord experience.","volume":"80","author":"Owen","year":"2010","journal-title":"ANZ J Surg"},{"key":"R99-18-20210119","first-page":"413","article-title":"Innovative management of anal fistula by use of the anal fistula plug: hype or help Minerva Chir.","volume":"63","author":"Schwander","year":"2008","journal-title":""},{"key":"R100-18-20210119","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1097\/DCR.0b013e31821df266","article-title":"Long-term efficacy of the button fistula plug in the treatment of ileal pouch-vaginal and Crohns-related rectovaginal fistulas.","volume":"54","author":"Gajsek","year":"2011","journal-title":"Dis Colon Rectum"}],"container-title":["Diseases of the Colon & Rectum"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.1097\/DCR.0b013e318239d1e4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T20:34:00Z","timestamp":1786048440000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00003453-201203000-00018"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,3]]},"references-count":100,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2012]]}},"URL":"https:\/\/doi.org\/10.1097\/dcr.0b013e318239d1e4","relation":{},"ISSN":["0012-3706"],"issn-type":[{"value":"0012-3706","type":"print"}],"subject":[],"published":{"date-parts":[[2012,3]]}}}