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Propolis is available as a dietary supplement, in products for the protection of health and prevention of diseases, in biopharmaceuticals, and as a constituent of (bio)cosmetics. In this article, the following aspects of propolis are reviewed: the nature and chemical composition, its biological properties and applications, contact allergy and allergic contact dermatitis (sensitizing potential, products causing contact allergy, clinical picture, frequency of sensitization, coreactivity and cross-reactivity, the allergens in propolis), and other adverse effects.<\/jats:p>","DOI":"10.1097\/der.0000000000000011","type":"journal-article","created":{"date-parts":[[2014,4,16]],"date-time":"2014-04-16T12:02:00Z","timestamp":1397649720000},"page":"263-282","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":210,"title":["Propolis"],"prefix":"10.1177","volume":"24","author":[{"given":"Anton C.","family":"de Groot","sequence":"first","affiliation":[{"name":"From Acdegroot Publishing, Wapserveen, the Netherlands."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2013,12,1]]},"reference":[{"key":"e_1_3_1_2_2","first-page":"163","article-title":"Propolis allergy (I)","volume":"17","author":"Hausen BM","year":"1987","unstructured":"Hausen BM, , Wollenweber E, , Senf H, et al. 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