{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T04:58:04Z","timestamp":1782968284729,"version":"3.54.5"},"reference-count":23,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2012,6,1]],"date-time":"2012-06-01T00:00:00Z","timestamp":1338508800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Dermatitis\u00ae"],"published-print":{"date-parts":[[2012,6,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The objective of this study was to determine whether contact allergens play a role in chronic idiopathic urticaria (CIU).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a longitudinal prospective study of 23 patients with CIU. Patients were patch tested to a modified North American Contact Dermatitis Group standard, fragrance, and cosmetic series; other series were tested as warranted by relevant history and physical examination. Readings were performed at 48 and 72 hours. Patients were counseled to avoid proven contact allergens and were followed up 2 to 9 months after testing.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Twenty-one of 23 patients were female. The mean age was 46 years. The mean duration of urticaria was 32 months. Of the 23 patients, 8 (35%) experienced improvement of their symptoms with allergen avoidance. Four (17%) experienced a complete remission, and 4 (17%) experienced partial improvement. Two of the complete responders challenged themselves to proven contact allergens and developed urticaria, which resolved upon allergen avoidance. The most common allergens were potassium dichromate (n = 9), nickel sulfate (n = 7),\n                      <jats:italic toggle=\"yes\">Myroxylon pereirae<\/jats:italic>\n                      (n = 6), cobalt chloride, neomycin,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      -phenylenediamine (n = 5); fragrance mix I, fragrance mix II (n = 4); cinnamic aldehyde (n = 3); and formaldehyde (n = 2).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Patch testing may be helpful in the evaluation of CIU patients for whom previous workup has failed to reveal an etiology.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1097\/der.0b013e318250b448","type":"journal-article","created":{"date-parts":[[2014,4,16]],"date-time":"2014-04-16T12:05:29Z","timestamp":1397649929000},"page":"110-116","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":18,"title":["The Role of Contact Allergens in Chronic Idiopathic Urticaria"],"prefix":"10.1177","volume":"23","author":[{"given":"Meghan T.","family":"Hession","sequence":"first","affiliation":[{"name":"From the Dermatology Department, Tufts Medical Center, Boston, MA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pamela L.","family":"Scheinman","sequence":"additional","affiliation":[{"name":"From the Dermatology Department, Tufts Medical Center, Boston, MA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2012,6,1]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2002.122759"},{"key":"e_1_3_2_3_2","first-page":"421","article-title":"Chronic urticaria: a model questionnaire for patient screening","volume":"46","author":"Gross AS","year":"1990","unstructured":"Gross AS, , Latour DL, , King LE. Chronic urticaria: a model questionnaire for patient screening. Cutis, 1990; 46: 421\u2013424.","journal-title":"Cutis"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1067\/mai.2000.105706"},{"key":"e_1_3_2_5_2","doi-asserted-by":"crossref","first-page":"196","DOI":"10.2340\/00015555-0240","article-title":"Urticaria: current opinions about etiology, diagnosis, and therapy","volume":"87","author":"Zuberbier T","year":"2007","unstructured":"Zuberbier T, , Maurer M. Urticaria: current opinions about etiology, diagnosis, and therapy. Acta Derm Venereol, 2007; 87: 196\u2013205.","journal-title":"Acta Derm Venereol"},{"issue":"3","key":"e_1_3_2_6_2","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.anai.2011.06.008","article-title":"Utility of routine laboratory testing in management of chronic urticaria\/angioedema","volume":"107","author":"Tarbox JA","year":"2011","unstructured":"Tarbox JA, , Gutta RC, , Radojicic C, et al.. Utility of routine laboratory testing in management of chronic urticaria\/angioedema. Ann Allergy Asthma Immunol, 2011; 107 (3): 239\u2013243.","journal-title":"Ann Allergy Asthma Immunol"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.2340\/0001555573438439"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1989.tb04744.x"},{"issue":"21","key":"e_1_3_2_9_2","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1056\/NEJM199311183292121","article-title":"Chronic urticaria due to surgical clips","volume":"329","author":"King L","year":"1993","unstructured":"King L, , Fransway A, , Benton Adkins R. Chronic urticaria due to surgical clips. 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