{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T13:15:58Z","timestamp":1777554958476,"version":"3.51.4"},"reference-count":17,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2012,8,1]],"date-time":"2012-08-01T00:00:00Z","timestamp":1343779200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Dermatitis\u00ae"],"published-print":{"date-parts":[[2012,8,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Sorbitan sesquioleate (SSO), an emulsifier in many corticosteroids, was previously found positive in 8.9% of 112 dermatitis patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The objective of this study was to present data on 24 of 591 dermatitis patients with reactions to SSO and\/or sorbitan monooleate (SMO) on patch testing.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective chart review was conducted on 591 consecutive dermatitis patients patch tested from November 2008 to May 2010. In addition to being tested to a modified North American Contact Dermatitis Group standard series, all patients were tested to a cosmetic series.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of the 591 patients tested, 24 reacted to SSO and\/or SMO (4.1%), 19 (3.2%) reacted to SSO alone, 1 (0.17%) to SMO alone, and 4 (0.68%) reacted to both. Of the 24 sorbitan-allergic patients, 2 (8.3%) reacted to any of 4 corticosteroid screening chemicals tested.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In this follow-up study, 4.1% of 591 dermatitis patients reacted to SSO and\/or SMO. Given the presence of SSO in many popular topical corticosteroid formulations, clinicians should consider allergy to sorbitans when patients do not improve with topical corticosteroid therapy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1097\/der.0b013e318260d75f","type":"journal-article","created":{"date-parts":[[2014,4,16]],"date-time":"2014-04-16T12:04:26Z","timestamp":1397649866000},"page":"158-161","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":17,"title":["Contact Allergy to Sorbitans: A Follow-up Study"],"prefix":"10.1177","volume":"23","author":[{"given":"Brienne D.","family":"Cressey","sequence":"first","affiliation":[{"name":"From the Tufts Medical Center, Department of Dermatology, Boston, MA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neal","family":"Kumar","sequence":"additional","affiliation":[{"name":"From the Tufts Medical Center, Department of Dermatology, Boston, MA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pamela L.","family":"Scheinman","sequence":"additional","affiliation":[{"name":"From the Tufts Medical Center, Department of Dermatology, Boston, MA."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2012,8,1]]},"reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.2310\/6620.2008.08029"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2007.01214.x"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.2310\/6620.2008.07054"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.2310\/6620.2008.08013"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2007.01075.x"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1994.tb00708.x"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1990.tb03225.x"},{"key":"e_1_3_1_9_2","first-page":"1438","article-title":"The penetration and permeation of drugs in skin","volume":"4","author":"Tuomi A","year":"1986","unstructured":"Tuomi A. The penetration and permeation of drugs in skin. Diagnosis, 1986; 4: 1438\u20131446.","journal-title":"Diagnosis"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1994.tb01993.x"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2010.11.004"},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.2310\/6620.2009.08097"},{"issue":"1","key":"e_1_3_1_13_2","first-page":"93","article-title":"Final report on the safety assessment of sorbitan caprylate, sorbitan cocoate, sorbitan diisostearate, sorbitan dioleate, sorbitan distearate, sorbitan isostearate, sorbitan olivate, sorbitan sesquiisostearate, sorbitan sesquistearate, and sorbitan triisostearate","volume":"21","author":"Lanigan RS","year":"2002","unstructured":"Lanigan RS, , Yamarik TA. Final report on the safety assessment of sorbitan caprylate, sorbitan cocoate, sorbitan diisostearate, sorbitan dioleate, sorbitan distearate, sorbitan isostearate, sorbitan olivate, sorbitan sesquiisostearate, sorbitan sesquistearate, and sorbitan triisostearate. 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