{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T13:24:47Z","timestamp":1792761887089,"version":"4.5.0"},"reference-count":8,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2013,8,1]],"date-time":"2013-08-01T00:00:00Z","timestamp":1375315200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Dermatitis\u00ae"],"published-print":{"date-parts":[[2013,8,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Metal hypersensitivity reactions to implanted devices remain a challenging and controversial topic. Diagnostic criteria and methods are not well delineated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Diagnostic criteria for hypersensitivity reactions after metallic device implantation are evaluated in this study by a multinational group of patch testers using Thyssen\u2019s previously published criteria.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 119 dermatologists at the 2012 European Contact Dermatitis Society and 2013 American Contact Dermatitis Society meetings answered a survey regarding their opinions on topics relating to metal hypersensitivity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Four major and 5 minor diagnostic criteria emerged. Approximately 80% of respondents found the following criteria useful (major criteria): chronic dermatitis beginning weeks to months after metallic implantation, eruption overlying the metal implant, positive patch test to a metal component of the implant, and complete clearing after removal of the potentially allergenic implant. Minor criteria (&lt;61% of respondents) were as follows: systemic allergic dermatitis reaction, therapy-resistant dermatitis, morphology consistent with dermatitis, histology consistent with allergic contact dermatitis, and a positive in vitro test to metals (eg, lymphocyte transformation test). In the challenging situation such as a symptomatic or failing orthopedic device, applying these 4 major criteria and the 5 supportive minor criteria may be useful for guiding decision making.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1097\/der.0b013e31829cb113","type":"journal-article","created":{"date-parts":[[2014,4,16]],"date-time":"2014-04-16T12:03:27Z","timestamp":1397649807000},"page":"183-185","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":35,"title":["Patch Testers\u2019 Opinions Regarding Diagnostic Criteria for Metal Hypersensitivity Reactions to Metallic Implants"],"prefix":"10.1177","volume":"24","author":[{"given":"Peter C.","family":"Schalock","sequence":"first","affiliation":[{"name":"From the *Department of Dermatology, Massachusetts General Hospital, Harvard School of Medicine, Boston"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacob P.","family":"Thyssen","sequence":"additional","affiliation":[{"name":"National Allergy Research Centre, Department of Dermato-Allergology, Gentofte Hospital, University of Copenhagen, Denmark."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2013,8,1]]},"reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.2310\/6620.2011.10055"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0b013e3182948251"},{"key":"e_1_3_1_4_2","first-page":"473","article-title":"Pragmatic approach to the clinical work-up of patients with putative allergic disease to metallic orthopaedic implants before and after surgery","volume":"164","author":"Thyssen JP","year":"2011","unstructured":"Thyssen JP, , Menn\u00e9 T, , Schalock PC, et al. Pragmatic approach to the clinical work-up of patients with putative allergic disease to metallic orthopaedic implants before and after surgery. Br J Dermatol, 2011; 164: 473\u2013478.","journal-title":"Br J Dermatol"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2011.01971.x"},{"key":"e_1_3_1_6_2","first-page":"62","article-title":"Implantation of orthopaedic devices in patients with metal allergy","volume":"69","author":"Carlsson A","year":"1989","unstructured":"Carlsson A, , M\u00f6ller H. Implantation of orthopaedic devices in patients with metal allergy. Acta Derm Venereol, 1989; 69: 62\u201366.","journal-title":"Acta Derm Venereol"},{"issue":"3","key":"e_1_3_1_7_2","doi-asserted-by":"crossref","first-page":"200","DOI":"10.3346\/jkms.1995.10.3.200","article-title":"Cobalt-induced occupational asthma associated with systemic illness","volume":"10","author":"Baik JJ","year":"1995","unstructured":"Baik JJ, , Yoon YB, , Park HS. Cobalt-induced occupational asthma associated with systemic illness. J Korean Med Sci. 1995; 10(3): 200\u2013204.","journal-title":"J Korean Med Sci"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2006.11.640"},{"key":"e_1_3_1_9_2","first-page":"129","article-title":"Intradermal testing and sublingual desensitization for nickel","volume":"61","author":"Morris DL","year":"1998","unstructured":"Morris DL. Intradermal testing and sublingual desensitization for nickel. Cutis, 1998; 61: 129\u2013132.","journal-title":"Cutis"}],"container-title":["Dermatitis\u00ae"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1097\/DER.0b013e31829cb113","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1097\/DER.0b013e31829cb113","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1097\/DER.0b013e31829cb113","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T18:08:07Z","timestamp":1777399687000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1097\/DER.0b013e31829cb113"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,8,1]]},"references-count":8,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2013,8,1]]}},"alternative-id":["10.1097\/DER.0b013e31829cb113"],"URL":"https:\/\/doi.org\/10.1097\/der.0b013e31829cb113","relation":{},"ISSN":["1710-3568","2162-5220"],"issn-type":[{"value":"1710-3568","type":"print"},{"value":"2162-5220","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,8,1]]}}}