{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T09:19:17Z","timestamp":1778318357009,"version":"3.51.4"},"reference-count":6,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":["Dermatol Surg","DS"],"published-print":{"date-parts":[[2026,3]]},"abstract":"\n BACKGROUND<\/jats:title>\n In the histologic analysis of melanoma, Breslow depth is a critical component of prognostication. Transecting the tumor through tangential biopsy technique potentially affects staging, treatment, and outcomes.<\/jats:p>\n <\/jats:sec>\n \n OBJECTIVE<\/jats:title>\n Compare outcomes of transected and nontransected melanomas biopsied by tangential biopsy technique.<\/jats:p>\n <\/jats:sec>\n \n PATIENTS AND METHODS<\/jats:title>\n This is a single-center retrospective cohort study. Patients were matched based on American Joint Commission on Cancer eighth edition Tumor (T) stage and tumor transection status.<\/jats:p>\n <\/jats:sec>\n \n RESULTS<\/jats:title>\n \n Patients with transected melanomas experienced significant increases in 5-year recurrence (\n p<\/jats:italic>\n = .023), 5-year mortality (\n p<\/jats:italic>\n = .004), metastasis (\n p<\/jats:italic>\n = .035), and melanoma-related mortality (\n p<\/jats:italic>\n = .002). However, after stratifying by T stage, there were no significant differences in recurrence, metastasis, or mortality between transected and nontransected tumors. Transected tumors <1.0 mm had a higher rate of sentinel lymph node biopsies (SNLB) performed compared with the nontransected tumors <1.0 mm. Limitations include population size, single-institution retrospective nature of the study, and homogenous population.\n <\/jats:p>\n <\/jats:sec>\n \n CONCLUSION<\/jats:title>\n While there were no significant differences in patient outcomes by T stage when melanomas were transected by shave biopsy, shallow (<1.0 mm) transected melanomas were more likely to receive sentinel lymph node biopsy compared with nontransected melanomas. Biopsy technique should aim to a depth that provides the full Breslow depth of melanoma tumors.<\/jats:p>\n <\/jats:sec>","DOI":"10.1097\/dss.0000000000004802","type":"journal-article","created":{"date-parts":[[2025,8,8]],"date-time":"2025-08-08T12:01:22Z","timestamp":1754654482000},"page":"212-215","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Outcomes of Transected Melanoma Diagnosed by Shave Biopsy: A Single-Institution Retrospective Analysis"],"prefix":"10.1097","volume":"52","author":[{"given":"David","family":"Griffin","sequence":"first","affiliation":[{"name":"Department of Dermatology, Marshfield Clinic Health System, Marshfield, Wisconsin;"},{"name":"Idaho Skin Institute, Twin Falls, Idaho"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erik J.","family":"Stratman","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Marshfield Clinic Health System, Marshfield, Wisconsin;"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","published-online":{"date-parts":[[2025,8,8]]},"reference":[{"key":"R3-20260227","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jaad.2015.06.033","article-title":"Skin biopsy: biopsy issues in specific diseases","volume":"74","author":"Elston","year":"2016","journal-title":"J Am Acad Dermatol"},{"key":"R4-20260227","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1016\/j.jaad.2017.04.1134","article-title":"Clinical and pathologic factors associated with deep transection of biopsies of invasive melanoma","volume":"77","author":"Woodcock","year":"2017","journal-title":"J Am Acad Dermatol"},{"key":"R5-20260227","doi-asserted-by":"crossref","first-page":"2105","DOI":"10.1245\/s10434-018-6513-7","article-title":"Melanoma Staging: American Joint Committee on cancer (AJCC) 8th edition and beyond","volume":"25","author":"Gershenwald","year":"2018","journal-title":"Ann Surg Oncol"},{"key":"R6-20260227","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1111\/j.1469-1809.1955.tb01348.x","article-title":"On estimating the relation between blood group and disease","volume":"19","author":"Woolf","year":"1955","journal-title":"Ann Hum Genet"},{"key":"R9-20260227","doi-asserted-by":"crossref","first-page":"5248","DOI":"10.1245\/s10434-020-08558-8","article-title":"Sentinel lymph node biopsy for T1b melanoma: balancing prognostic value and cost","volume":"27","author":"Hu","year":"2020","journal-title":"Ann Surg Oncol"},{"key":"R10-20260227","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1186\/s12885-024-12426-z","article-title":"Patterns and trends in melanoma mortality in the United States, 1999\u20132020","volume":"24","author":"Didier","year":"2024","journal-title":"BMC Cancer"}],"container-title":["Dermatologic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/DSS.0000000000004802","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T14:02:36Z","timestamp":1772200956000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.1097\/DSS.0000000000004802"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,8]]},"references-count":6,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.1097\/dss.0000000000004802","relation":{},"ISSN":["1076-0512","1524-4725"],"issn-type":[{"value":"1076-0512","type":"print"},{"value":"1524-4725","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,8]]}}}