{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,25]],"date-time":"2025-02-25T05:40:02Z","timestamp":1740462002415,"version":"3.37.3"},"reference-count":44,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010,10]]},"DOI":"10.1097\/fbp.0b013e32833e7eab","type":"journal-article","created":{"date-parts":[[2010,8,27]],"date-time":"2010-08-27T15:12:18Z","timestamp":1282921938000},"page":"649-653","source":"Crossref","is-referenced-by-count":7,"title":["Quetiapine anxiolytic-like effect in the Vogel conflict test is serotonin dependent"],"prefix":"10.1097","volume":"21","author":[{"given":"Carla","family":"Pisu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luigi","family":"Pira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luca","family":"Pani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R2-7-20210202","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1002\/da.10137","article-title":"Preliminary experience with adjunctive quetiapine in patients receiving selective serotonin reuptake inhibitors","volume":"19","author":"Adson","year":"2004","journal-title":"Depress Anxiety"},{"key":"R3-7-20210202","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1016\/S0028-3908(03)00304-6","article-title":"Regulation by 5-HT1A receptors of the in vivo release of 5-HT and DA in mouse frontal cortex","volume":"45","author":"Ago","year":"2003","journal-title":"Neuropharmacology"},{"key":"R4-7-20210202","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1016\/j.biopsych.2009.03.012","article-title":"The serotonin-1A receptor in anxiety disorders","volume":"66","author":"Akimova","year":"2009","journal-title":"Biol Psychiatry"},{"key":"R6-7-20210202","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1017\/S1461145709990423","article-title":"Extended-release quetiapine fumarate (quetiapine XR): a once-daily monotherapy effective in generalized anxiety disorder. Data from a randomized, double-blind, placebo- and active-controlled study","volume":"13","author":"Bandelow","year":"2010","journal-title":"Int J Neuropsychopharmacol"},{"key":"R7-7-20210202","first-page":"59","article-title":"5HT1A agonists, 5HT3 antagonists and benzodiazepines, their comparative behavioural pharmacology","author":"Barret","year":"1991"},{"key":"R8-7-20210202","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.2147\/NDT.S3238","article-title":"New developments in the management of major depressive disorder and generalized anxiety disorder: role of quetiapine","volume":"4","author":"Baune","year":"2008","journal-title":"Neuropsychiatr Dis Treat"},{"key":"R11-7-20210202","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/j.bbr.2009.08.010","article-title":"Involvement of the serotonergic system in the anxiolytic-like effect caused by m-trifluoromethyl-diphenyl diselenide in mice","volume":"205","author":"Bruning","year":"2009","journal-title":"Behav Brain Res"},{"key":"R12-7-20210202","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.neuroscience.2010.01.062","article-title":"Facilitation of endocannabinoid effects in the ventral hippocampus modulates anxiety-like behaviors depending on previous stress experience","volume":"167","author":"Campos","year":"2010","journal-title":"Neuroscience"},{"key":"R14-7-20210202","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1016\/0091-3057(95)00189-4","article-title":"5-HT1A receptor full and partial agonists and 5-HT2C (but not 5-HT3) receptor antagonists increase rates of punished responding in rats","volume":"52","author":"Cervo","year":"1995","journal-title":"Pharmacol Biochem Behav"},{"key":"R15-7-20210202","first-page":"1301","article-title":"Psycopharmacology: the fourth generation of progress","author":"Coplan","year":"1995"},{"key":"R16-7-20210202","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1002\/da.20633","article-title":"What is an anxiety disorder?","volume":"26","author":"Craske","year":"2009","journal-title":"Depress Anxiety"},{"key":"R17-7-20210202","first-page":"87","article-title":"Psychopharmacology of depression","author":"Deakin","year":"1994"},{"key":"R18-7-20210202","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.4088\/JCP.v65n0803","article-title":"A double-blind, randomized, placebo-controlled trial of quetiapine addition in patients with obsessive-compulsive disorder refractory to serotonin reuptake inhibitors","volume":"65","author":"Denys","year":"2004","journal-title":"J Clin Psychiatry"},{"key":"R19-7-20210202","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1586\/ern.09.37","article-title":"Atypical antipsychotics in primary generalized anxiety disorder or comorbid with mood disorders","volume":"9","author":"Gao","year":"2009","journal-title":"Expert Rev Neurother"},{"key":"R20-7-20210202","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/j.euroneuro.2009.01.011","article-title":"Research in anxiety disorders: from the bench to the bedside","volume":"19","author":"Garner","year":"2009","journal-title":"Eur Neuropsychopharmacol"},{"key":"R21-7-20210202","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1016\/S0306-4522(99)00211-0","article-title":"Buspirone modulates basal and fluoxetine-stimulated dialysate levels of dopamine, noradrenaline and serotonin in the frontal cortex of freely moving rats: activation of serotonin1A receptors and blockade of alpha2-adrenergic receptors underlie its actions","volume":"93","author":"Gobert","year":"1999","journal-title":"Neuroscience"},{"key":"R22-7-20210202","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1007\/s00213-002-1112-4","article-title":"On serotonin and experimental anxiety","volume":"163","author":"Graeff","year":"2002","journal-title":"Psychopharmacology (Berl)"},{"key":"R23-7-20210202","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1016\/S0149-7634(96)00059-0","article-title":"Dual role of 5-HT in defense and anxiety","volume":"21","author":"Graeff","year":"1997","journal-title":"Neurosci Biobehav Rev"},{"key":"R24-7-20210202","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1016\/S0028-3908(97)00034-8","article-title":"A comparative study of the effects of selective and non-selective 5-HT2 receptor subtype antagonists in rat and mouse models of anxiety","volume":"36","author":"Griebel","year":"1997","journal-title":"Neuropharmacology"},{"key":"R25-7-20210202","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/S0028-3908(98)00175-0","article-title":"Influence of 5-HT1A receptors on central noradrenergic activity: microdialysis studies using (\u00b1)-MDL 73005EF and its enantiomers","volume":"38","author":"Hajos-Korcsok","year":"1999","journal-title":"Neuropharmacology"},{"key":"R26-7-20210202","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1097\/00004714-200302000-00003","article-title":"Quetiapine treatment in patients with posttraumatic stress disorder: an open trial of adjunctive therapy","volume":"23","author":"Hamner","year":"2003","journal-title":"J Clin Psychopharmacol"},{"key":"R27-7-20210202","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/0163-7258(95)00004-Z","article-title":"5-hydroxytryptamine pathways in anxiety and its treatment","volume":"66","author":"Handley","year":"1995","journal-title":"Pharmacol Ther"},{"key":"R28-7-20210202","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1124\/jpet.102.046987","article-title":"Antipsychotic dosing in preclinical models is often unrepresentative of the clinical condition: a suggested solution based on in vivo occupancy","volume":"305","author":"Kapur","year":"2003","journal-title":"J Pharmacol Exp Ther"},{"key":"R29-7-20210202","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1007\/s00213-008-1121-z","article-title":"Antagonism of AMPA receptors produces anxiolytic-like behavior in rodents: effects of GYKI 52466 and its novel analogues","volume":"198","author":"Kapus","year":"2008","journal-title":"Psychopharmacology (Berl)"},{"key":"R30-7-20210202","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.1016\/j.janxdis.2008.03.002","article-title":"Quetiapine as an adjunctive pharmacotherapy for the treatment of non-remitting generalized anxiety disorder: a flexible-dose, open-label pilot trial","volume":"22","author":"Katzman","year":"2008","journal-title":"J Anxiety Disord"},{"key":"R31-7-20210202","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1016\/S0006-3223(98)00187-5","article-title":"Serotonergic basis of antipsychotic drug effects in schizophrenia","volume":"44","author":"Lieberman","year":"1998","journal-title":"Biol Psychiatry"},{"key":"R32-7-20210202","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1002\/da.20275","article-title":"Quetiapine adjunct to selective serotonin reuptake inhibitors or venlafaxine in patients with major depression, comorbid anxiety, and residual depressive symptoms: a randomized, placebo-controlled pilot study","volume":"24","author":"McIntyre","year":"2007a","journal-title":"Depress Anxiety"},{"key":"R33-7-20210202","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1517\/14656566.8.9.1211","article-title":"A preclinical and clinical rationale for quetiapine in mood syndromes","volume":"8","author":"McIntyre","year":"2007b","journal-title":"Expert Opin Pharmacother"},{"key":"R34-7-20210202","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1007\/BF02245590","article-title":"Aggression, anxiety and vocalizations in animals: GABAA and 5-HT anxiolytics","volume":"121","author":"Miczek","year":"1995","journal-title":"Psychopharmacology (Berl)"},{"key":"R35-7-20210202","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1016\/S0022-3565(24)38982-7","article-title":"Improving the treatment of schizophrenia: focus on serotonin (5-HT)(1A) receptors","volume":"295","author":"Millan","year":"2000","journal-title":"J Pharmacol Exp Ther"},{"key":"R36-7-20210202","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/S0014-2999(03)01275-5","article-title":"The Vogel conflict test: procedural aspects, gamma-aminobutyric acid, glutamate and monoamines","volume":"463","author":"Millan","year":"2003","journal-title":"Eur J Pharmacol"},{"key":"R39-7-20210202","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1254\/jphs.09139FP","article-title":"Morphine, oxycodone, and fentanyl exhibit different analgesic profiles in mouse pain models","volume":"111","author":"Minami","year":"2009","journal-title":"J Pharmacol Sci"},{"key":"R40-7-20210202","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1016\/S0022-3565(25)12304-5","article-title":"Differential genetic mediation of sensitivity to morphine in genetic models of opiate antinociception: influence of nociceptive assay","volume":"276","author":"Mogil","year":"1996","journal-title":"J Pharmacol Exp Ther"},{"key":"R41-7-20210202","doi-asserted-by":"crossref","first-page":"1466","DOI":"10.1016\/j.pnpbp.2006.06.004","article-title":"Anxiolytic-like effect of cannabidiol in the rat Vogel conflict test","volume":"30","author":"Moreira","year":"2006","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"R42-7-20210202","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S0014-2999(01)01005-6","article-title":"Anxiolytic effects of aniracetam in three different mouse models of anxiety and the underlying mechanism","volume":"420","author":"Nakamura","year":"2001","journal-title":"Eur J Pharmacol"},{"key":"R43-7-20210202","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1517\/14728214.12.4.541","article-title":"Emerging anxiolytics","volume":"12","author":"Pillay","year":"2007","journal-title":"Expert Opin Emerg Drugs"},{"key":"R44-7-20210202","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.physbeh.2007.08.009","article-title":"Anxiolytic-like effects induced by medial prefrontal cortex inhibition in rats submitted to the Vogel conflict test","volume":"93","author":"Resstel","year":"2008","journal-title":"Physiol Behav"},{"key":"R45-7-20210202","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1007\/s11920-003-0062-9","article-title":"Treatment for mood and anxiety disorders: quetiapine and aripiprazole","volume":"5","author":"Sajatovic","year":"2003","journal-title":"Curr Psychiatry Rep"},{"key":"R46-7-20210202","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0163-7258(00)00082-6","article-title":"The psychobiology of anxiolytic drugs. Part 1: basic neurobiology","volume":"88","author":"Sandford","year":"2000","journal-title":"Pharmacol Ther"},{"key":"R47-7-20210202","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1111\/j.1476-5381.2008.00025.x","article-title":"Anti-nociceptive properties of the xanthine oxidase inhibitor allopurinol in mice: role of A1 adenosine receptors","volume":"156","author":"Schmidt","year":"2009","journal-title":"Br J Pharmacol"},{"key":"R48-7-20210202","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/0278-5846(93)90034-P","article-title":"5-HT1A receptor ligands in animal models of anxiety, impulsivity and depression: multiple mechanisms of action?","volume":"17","author":"Schreiber","year":"1993","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"R49-7-20210202","doi-asserted-by":"crossref","first-page":"88","DOI":"10.3928\/0048-5713-19960201-09","article-title":"The 5HT1A receptor system: possible implications for schizophrenic negative symptomatology","volume":"26","author":"Sharma","year":"1996","journal-title":"Psychiatric Ann"},{"key":"R50-7-20210202","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF00403989","article-title":"A simple and reliable conflict procedure for testing anti-anxiety agents","volume":"21","author":"Vogel","year":"1971","journal-title":"Psychopharmacologia"},{"key":"R51-7-20210202","doi-asserted-by":"crossref","first-page":"263","DOI":"10.33549\/physiolres.931756","article-title":"Quetiapine ameliorates anxiety-like behavior and cognitive impairments in stressed rats: implications for the treatment of posttraumatic stress disorder","volume":"59","author":"Wang","year":"2010","journal-title":"Physiol Res"}],"container-title":["Behavioural Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/journals.lww.com\/00008877-201010000-00007","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,25]],"date-time":"2025-02-25T04:45:26Z","timestamp":1740458726000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00008877-201010000-00007"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,10]]},"references-count":44,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2010]]}},"URL":"https:\/\/doi.org\/10.1097\/fbp.0b013e32833e7eab","relation":{},"ISSN":["0955-8810"],"issn-type":[{"type":"print","value":"0955-8810"}],"subject":[],"published":{"date-parts":[[2010,10]]}}}