{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T04:45:07Z","timestamp":1789706707575,"version":"4.0.1"},"reference-count":19,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2009,11]]},"DOI":"10.1097\/fjc.0b013e3181be7578","type":"journal-article","created":{"date-parts":[[2009,11,12]],"date-time":"2009-11-12T03:15:57Z","timestamp":1257995757000},"page":"451-455","source":"Crossref","is-referenced-by-count":20,"title":["Upregulation of OX40\u2013OX40 Ligand System on T Lymphocytes in Patients With Acute Coronary Syndromes"],"prefix":"10.1097","volume":"54","author":[{"given":"JinChuan","family":"Yan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"GuangHua","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Gong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"CuiPing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rongzeng","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-14-20210208","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1161\/hc0902.104353","article-title":"Inflammation and atherosclerosis.","volume":"105","author":"Libby","year":"2002","journal-title":"Circulation"},{"key":"R2-14-20210208","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1038\/nri1882","article-title":"The immune response in atherosclerosis: a double-edged sword.","volume":"6","author":"Hansson","year":"2006","journal-title":"Nat Rev Immunol"},{"key":"R3-14-20210208","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1152\/physrev.00024.2005","article-title":"Cytokines in atherosclerosis: pathogenic and regulatory pathways.","volume":"86","author":"Tedgui","year":"2006","journal-title":"Physiol Rev"},{"key":"R4-14-20210208","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1111\/j.1365-2567.2005.02279.x","article-title":"Activated T cells express the OX40 ligand: requirments for induction and costimulatory function.","volume":"117","author":"Mendel","year":"2006","journal-title":"Immunology"},{"key":"R5-14-20210208","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.cca.2008.07.003","article-title":"The clinical implications of increased OX40 ligand expression in patients with acute coronary syndrome.","volume":"397","author":"Liu","year":"2008","journal-title":"Clin Chim Acta"},{"key":"R6-14-20210208","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1161\/01.CIR.97.5.425","article-title":"Plasma concentration of C-reactive protein and risk of developing peripheral vascular disease.","volume":"97","author":"Ridker","year":"1998","journal-title":"Circulation"},{"key":"R7-14-20210208","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1038\/nri1148","article-title":"Co-stimulatory members of the TNFR family:keys to effective T-cell immunity?","volume":"3","author":"Croft","year":"2003","journal-title":"Nat Rev Immunol"},{"key":"R8-14-20210208","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1038\/nri1371","article-title":"Therapeutic targeting if the effector T-cell co-stimulatory molecule OX40.","volume":"4","author":"Sugamura","year":"2004","journal-title":"Nat Rev Immunol"},{"key":"R9-14-20210208","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1038\/ng1524","article-title":"Positional idendification of TNFSF4, encodingOX40 ligand, as a gene that inflences atherosclerosis susceptibility.","volume":"4","author":"Wang","year":"2005","journal-title":"Nat Genet"},{"key":"R10-14-20210208","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1161\/01.ATV.0000251007.07648.81","article-title":"Interruption of the Tnfrsf4\/Tnfsf4(OX40\/OX40L) pathway attenuates atherogenesis in low-density lipoprotein receptor-deficient mice.","volume":"27","author":"Van Wanrooij","year":"2007","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"R11-14-20210208","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1016\/j.bbrc.2005.11.092","article-title":"Human genetic evidence that OX40 is implicated in myocardial infarction.","volume":"339","author":"Ria","year":"2006","journal-title":"Biochem Biophys Res Commun"},{"key":"R12-14-20210208","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.ijcard.2005.06.021","article-title":"C-reactive protein in patients with acute coronary syndrome: correlation with diagnosis, myocardial damage, ejection fraction and angiographic findings.","volume":"109","author":"Brunetti","year":"2006","journal-title":"Int J Cardiol"},{"key":"R13-14-20210208","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1253\/circj.70.1379","article-title":"Incremental prognostic value of C-reactive protein and N-terminal proB-type natriuretic peptide in acute coronary syndrome.","volume":"70","author":"Kim","year":"2006","journal-title":"Circ J"},{"key":"R14-14-20210208","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1007\/s00059-004-2577-1","article-title":"Time-dependent changes of hs-CRP serum concentration in patients with non-ST elevation acute coronary syndrome.","volume":"29","author":"Jahn","year":"2004","journal-title":"Herz"},{"key":"R15-14-20210208","first-page":"159","article-title":"The effect of elevated serum soluble CD40 ligand on the prognotic value in patients with acute coronary syndromes.","volume":"155-","author":"Yan","year":"2004","journal-title":"Clin Chim Acta"},{"key":"R16-14-20210208","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1056\/NEJM200003233421202","article-title":"C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women.","volume":"342","author":"Ridker","year":"2000","journal-title":"N Engl J Med"},{"key":"R17-14-20210208","doi-asserted-by":"crossref","first-page":"486","DOI":"10.4049\/jimmunol.162.1.486","article-title":"Regulation of T cell activation in vitro and in vivo by targeting the OX40-OX40 ligand interaction: amelioration of ongoing inflammatory bowel disease with an OX40-IgG fusion protein, but not with an OX40 ligand-IgG fusion protein.","volume":"162","author":"Higgins","year":"1999","journal-title":"J Immunol"},{"key":"R18-14-20210208","doi-asserted-by":"crossref","first-page":"2108","DOI":"10.4049\/jimmunol.166.3.2108","article-title":"Amelioration of experimental autoimmune encephalomyelitis with anti-OX40 ligand monoclonal antibody: a critical role for OX40 ligand in migration, but not development of pathogenic T cells.","volume":"166","author":"Nohara","year":"2001","journal-title":"J Immunol"},{"key":"R19-14-20210208","doi-asserted-by":"crossref","first-page":"3597","DOI":"10.1002\/eji.200636975","article-title":"Blockade of the OX40 ligand prolongs corneal allograft survival.","volume":"37","author":"Hattori","year":"2007","journal-title":"Eur J Immunol"}],"container-title":["Journal of Cardiovascular Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00005344-200911000-00014","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T18:08:00Z","timestamp":1786039680000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00005344-200911000-00014"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,11]]},"references-count":19,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2009]]}},"URL":"https:\/\/doi.org\/10.1097\/fjc.0b013e3181be7578","relation":{},"ISSN":["0160-2446"],"issn-type":[{"value":"0160-2446","type":"print"}],"subject":[],"published":{"date-parts":[[2009,11]]}}}