{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T22:43:10Z","timestamp":1791067390675,"version":"4.1.0"},"reference-count":57,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Cardiovascular Pharmacology"],"published-print":{"date-parts":[[2010,12]]},"DOI":"10.1097\/fjc.0b013e3181e1d263","type":"journal-article","created":{"date-parts":[[2010,6,8]],"date-time":"2010-06-08T05:35:45Z","timestamp":1275975345000},"page":"598-603","source":"Crossref","is-referenced-by-count":55,"title":["Cardiac Hypertrophy and Heart Failure Development Through Gq and CaM Kinase II Signaling"],"prefix":"10.1097","volume":"56","author":[{"given":"Shikha","family":"Mishra","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haiyun","family":"Ling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Grimm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Don M","family":"Bers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joan Heller","family":"Brown","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R2-4-20101208","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1146\/annurev.physiol.65.092101.142243","volume":"65","author":"Frey","year":"2003","journal-title":"Annu Rev Physiol"},{"key":"R3-4-20101208","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1161\/01.RES.83.2.167","volume":"83","author":"Adams","year":"1998","journal-title":"Circ Res"},{"key":"R4-4-20101208","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1074\/jbc.271.2.1179","volume":"271","author":"Adams","year":"1996","journal-title":"J Biol Chem"},{"key":"R5-4-20101208","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1161\/01.RES.51.6.787","volume":"51","author":"Simpson","year":"1982","journal-title":"Circ Res"},{"key":"R6-4-20101208","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1172\/JCI111023","volume":"72","author":"Simpson","year":"1983","journal-title":"J Clin Invest"},{"key":"R7-4-20101208","doi-asserted-by":"crossref","first-page":"20555","DOI":"10.1016\/S0021-9258(17)30538-0","volume":"265","author":"Shubeita","year":"1990","journal-title":"J Biol Chem"},{"key":"R8-4-20101208","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1172\/JCI116579","volume":"92","author":"Ito","year":"1993","journal-title":"J Clin Invest"},{"key":"R9-4-20101208","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1016\/0092-8674(93)90541-W","volume":"75","author":"Sadoshima","year":"1993","journal-title":"Cell"},{"key":"R10-4-20101208","doi-asserted-by":"crossref","first-page":"15374","DOI":"10.1016\/S0021-9258(18)82267-0","volume":"268","author":"Knowlton","year":"1993","journal-title":"J Biol Chem"},{"key":"R11-4-20101208","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1126\/science.1846707","volume":"251","author":"Smrcka","year":"1991","journal-title":"Science"},{"key":"R12-4-20101208","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1038\/350516a0","volume":"350","author":"Taylor","year":"1991","journal-title":"Nature"},{"key":"R13-4-20101208","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/S1050-1738(99)00004-3","volume":"9","author":"Dorn","year":"1999","journal-title":"Trends Cardiovasc Med"},{"key":"R14-4-20101208","doi-asserted-by":"crossref","first-page":"10140","DOI":"10.1073\/pnas.95.17.10140","volume":"95","author":"Adams","year":"1998","journal-title":"Proc Natl Acad Sci U S A"},{"key":"R15-4-20101208","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1161\/01.RES.87.12.1180","volume":"87","author":"Adams","year":"2000","journal-title":"Circ Res"},{"key":"R16-4-20101208","doi-asserted-by":"crossref","first-page":"8121","DOI":"10.1073\/pnas.94.15.8121","volume":"94","author":"DAngelo","year":"1997","journal-title":"Proc Natl Acad Sci U S A"},{"key":"R17-4-20101208","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1126\/science.280.5363.574","volume":"280","author":"Akhter","year":"1998","journal-title":"Science"},{"key":"R18-4-20101208","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1038\/nm1101-1236","volume":"7","author":"Wettschureck","year":"2001","journal-title":"Nat Med"},{"key":"R19-4-20101208","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1161\/01.RES.57.4.532","volume":"57","author":"Brown","year":"1985","journal-title":"Circ Res"},{"key":"R20-4-20101208","first-page":"H130","volume":"272","author":"Hilal-Dandan","year":"1997","journal-title":"Am J Physiol"},{"key":"R21-4-20101208","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/0165-6147(84)90490-5","volume":"5","author":"Brown","year":"1984","journal-title":"Trends Pharmacol Sci"},{"key":"R22-4-20101208","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1172\/JCI24178","volume":"115","author":"Dorn","year":"2005","journal-title":"J Clin Invest"},{"key":"R23-4-20101208","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1161\/01.RES.0000241053.89089.c3","volume":"99","author":"Clerk","year":"2006","journal-title":"Circ Res"},{"key":"R24-4-20101208","doi-asserted-by":"crossref","first-page":"15910","DOI":"10.1016\/S0021-9258(18)98495-4","volume":"266","author":"Sei","year":"1991","journal-title":"J Biol Chem"},{"key":"R25-4-20101208","doi-asserted-by":"crossref","first-page":"15912","DOI":"10.1074\/jbc.M414212200","volume":"280","author":"Bare","year":"2005","journal-title":"J Biol Chem"},{"key":"R26-4-20101208","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1083\/jcb.126.4.839","volume":"126","author":"Srinivasan","year":"1994","journal-title":"J Cell Biol"},{"key":"R27-4-20101208","doi-asserted-by":"crossref","first-page":"31203","DOI":"10.1074\/jbc.272.49.31203","volume":"272","author":"Ramirez","year":"1997","journal-title":"J Biol Chem"},{"key":"R28-4-20101208","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1172\/JCI27374","volume":"116","author":"Wu","year":"2006","journal-title":"J Clin Invest"},{"key":"R29-4-20101208","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.1161\/01.RES.0000172556.05576.4c","volume":"96","author":"Li","year":"2005","journal-title":"Circ Res"},{"key":"R30-4-20101208","doi-asserted-by":"crossref","first-page":"14400","DOI":"10.1073\/pnas.260501497","volume":"97","author":"McKinsey","year":"2000","journal-title":"Proc Natl Acad Sci U S A"},{"key":"R31-4-20101208","doi-asserted-by":"crossref","first-page":"1937","DOI":"10.1101\/gad.1110103","volume":"17","author":"Olson","year":"2003","journal-title":"Genes Dev"},{"key":"R32-4-20101208","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1210\/me.2002-0350","volume":"17","author":"Colomer","year":"2003","journal-title":"Mol Endocrinol"},{"key":"R33-4-20101208","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1161\/01.RES.0000069686.31472.C5","volume":"92","author":"Zhang","year":"2003","journal-title":"Circ Res"},{"key":"R34-4-20101208","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1016\/S0022-2828(03)00234-7","volume":"35","author":"Saito","year":"2003","journal-title":"J Mol Cell Cardiol"},{"key":"R35-4-20101208","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1074\/jbc.M108525200","volume":"277","author":"Zhang","year":"2002","journal-title":"J Biol Chem"},{"key":"R36-4-20101208","doi-asserted-by":"crossref","first-page":"35078","DOI":"10.1074\/jbc.M707083200","volume":"282","author":"Zhang","year":"2007","journal-title":"J Biol Chem"},{"key":"R37-4-20101208","doi-asserted-by":"crossref","first-page":"4070","DOI":"10.1073\/pnas.080064097","volume":"97","author":"Lu","year":"2000","journal-title":"Proc Natl Acad Sci U S A"},{"key":"R38-4-20101208","doi-asserted-by":"crossref","first-page":"8374","DOI":"10.1128\/MCB.24.19.8374-8385.2004","volume":"24","author":"Vega","year":"2004","journal-title":"Mol Cell Biol"},{"key":"R39-4-20101208","doi-asserted-by":"crossref","first-page":"1853","DOI":"10.1172\/JCI27438","volume":"116","author":"Backs","year":"2006","journal-title":"J Clin Invest"},{"key":"R40-4-20101208","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1161\/01.RES.0000069685.20258.F1","volume":"92","author":"Maier","year":"2003","journal-title":"Circ Res"},{"key":"R41-4-20101208","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1161\/01.RES.75.3.401","volume":"75","author":"Luo","year":"1994","journal-title":"Circ Res"},{"key":"R42-4-20101208","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1161\/CIRCRESAHA.109.207423","volume":"106","author":"Zhang","year":"2009","journal-title":"Circ Res"},{"key":"R43-4-20101208","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1172\/JCI38022","volume":"119","author":"Ling","year":"2009","journal-title":"J Clin Invest"},{"key":"R44-4-20101208","doi-asserted-by":"crossref","first-page":"3059","DOI":"10.1073\/pnas.0712265105","volume":"105","author":"Fielitz","year":"2008","journal-title":"Proc Natl Acad Sci U S A"},{"key":"R45-4-20101208","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1161\/01.RES.0000194329.41863.89","volume":"97","author":"Ai","year":"2005","journal-title":"Circ Res"},{"key":"R46-4-20101208","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1016\/j.yjmcc.2009.10.016","volume":"48","author":"Grimm","year":"2009","journal-title":"J Mol Cell Cardiol"},{"key":"R47-4-20101208","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/1050-1738(92)90026-O","volume":"2","author":"Brown","year":"1992","journal-title":"Trends Cardiovasc Med"},{"key":"R48-4-20101208","doi-asserted-by":"crossref","first-page":"1488","DOI":"10.1161\/01.CIR.97.15.1488","volume":"97","author":"Sakata","year":"1998","journal-title":"Circulation"},{"key":"R49-4-20101208","doi-asserted-by":"crossref","first-page":"3036","DOI":"10.1161\/01.CIR.0000101920.72665.58","volume":"108","author":"Hayakawa","year":"2003","journal-title":"Circulation"},{"key":"R50-4-20101208","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1038\/nm719","volume":"8","author":"Yussman","year":"2002","journal-title":"Nat Med"},{"key":"R51-4-20101208","first-page":"203","volume":"119","author":"Diwan","year":"2009","journal-title":"J Clin Invest"},{"key":"R52-4-20101208","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1038\/nm1215","volume":"11","author":"Zhang","year":"2005","journal-title":"Nat Med"},{"key":"R53-4-20101208","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/j.cardiores.2006.12.003","volume":"73","author":"Vila-Petroff","year":"2007","journal-title":"Crdiovasc Res"},{"key":"R54-4-20101208","doi-asserted-by":"crossref","first-page":"25063","DOI":"10.1074\/jbc.M302193200","volume":"278","author":"Ji","year":"2003","journal-title":"J Biol Chem"},{"key":"R55-4-20101208","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1038\/nature03434","volume":"434","author":"Baines","year":"2005","journal-title":"Nature"},{"key":"R56-4-20101208","doi-asserted-by":"crossref","first-page":"10833","DOI":"10.1074\/jbc.M611507200","volume":"282","author":"Zhu","year":"2007","journal-title":"J Biol Chem"},{"key":"R57-4-20101208","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1161\/CIRCRESAHA.109.210914","volume":"106","author":"Peng","year":"2010","journal-title":"Circ Res"},{"key":"R58-4-20101208","doi-asserted-by":"crossref","first-page":"24857","DOI":"10.1074\/jbc.M109.003186","volume":"284","author":"Little","year":"2009","journal-title":"J Biol Chem"}],"container-title":["Journal of Cardiovascular Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00005344-201012000-00004","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T18:22:54Z","timestamp":1786040574000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00005344-201012000-00004"}},"subtitle":[""],"short-title":[],"issued":{"date-parts":[[2010,12]]},"references-count":57,"journal-issue":{"issue":"6"},"URL":"https:\/\/doi.org\/10.1097\/fjc.0b013e3181e1d263","relation":{},"ISSN":["0160-2446"],"issn-type":[{"value":"0160-2446","type":"print"}],"subject":[],"published":{"date-parts":[[2010,12]]}}}