{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T16:47:30Z","timestamp":1791218850609,"version":"4.1.0"},"reference-count":99,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Cardiovascular Pharmacology"],"published-print":{"date-parts":[[2012,7]]},"DOI":"10.1097\/fjc.0b013e318252452a","type":"journal-article","created":{"date-parts":[[2012,3,8]],"date-time":"2012-03-08T20:33:31Z","timestamp":1331238811000},"page":"100-108","source":"Crossref","is-referenced-by-count":21,"title":["Neurogenic and Endothelial Nitric Oxide Regulates Blood Circulation in Lingual and Other Oral Tissues"],"prefix":"10.1097","volume":"60","author":[{"given":"Noboru","family":"Toda","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuhide","family":"Ayajiki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomio","family":"Okamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-13-20120706","doi-asserted-by":"crossref","first-page":"R568","DOI":"10.1152\/ajpcell.1989.257.3.C568","volume":"257","author":"Langille","year":"1989","journal-title":"Am J Physiol"},{"key":"R2-13-20120706","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1124\/pr.55.2.3","volume":"55","author":"Toda","year":"2003","journal-title":"Pharmacol Rev"},{"key":"R3-13-20120706","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1124\/pr.108.000547","volume":"61","author":"Toda","year":"2009","journal-title":"Pharmacol Rev"},{"key":"R4-13-20120706","doi-asserted-by":"crossref","first-page":"2656","DOI":"10.1161\/CIRCULATIONAHA.108.822205","volume":"119","author":"Seddon","year":"2009","journal-title":"Circulation"},{"key":"R5-13-20120706","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000317395","volume":"48","author":"Toda","year":"2011","journal-title":"J Vasc Res"},{"key":"R6-13-20120706","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ejphar.2010.09.042","volume":"649","author":"Toda","year":"2010","journal-title":"Eur J Pharmacol"},{"key":"R7-13-20120706","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1093\/alcalc\/agq028","volume":"45","author":"Toda","year":"2010","journal-title":"Alcohol Alcohol"},{"key":"R8-13-20120706","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1007\/s11906-999-0078-6","volume":"1","author":"Busse","year":"1999","journal-title":"Curr Hypertens Rep"},{"key":"R9-13-20120706","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.pharmthera.2010.04.009","volume":"127","author":"Toda","year":"2010","journal-title":"Pharmacol Ther"},{"key":"R10-13-20120706","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1038\/347768a0","volume":"347","author":"Bredt","year":"1990","journal-title":"Nature"},{"key":"R11-13-20120706","doi-asserted-by":"crossref","first-page":"15583","DOI":"10.1074\/jbc.272.25.15583","volume":"272","author":"Michel","year":"1997","journal-title":"J Biol Chem"},{"key":"R12-13-20120706","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1038\/21224","volume":"399","author":"Dimmeler","year":"1999","journal-title":"Nature"},{"key":"R13-13-20120706","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/0006-291X(90)91275-W","volume":"170","author":"Toda","year":"1990","journal-title":"Biochem Biophys Res Commun"},{"key":"R14-13-20120706","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1111\/j.1476-5381.1993.tb12798.x","volume":"108","author":"Moore","year":"1993","journal-title":"Br J Pharmacol"},{"key":"R15-13-20120706","first-page":"H1582","volume":"272","author":"Toda","year":"1997","journal-title":"Am J Physiol"},{"key":"R16-13-20120706","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0014-2999(98)00425-7","volume":"354","author":"Okamura","year":"1998","journal-title":"Eur J Pharmacol"},{"key":"R17-13-20120706","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/0165-1838(81)90039-4","volume":"4","author":"Nagai","year":"1981","journal-title":"J Auton Nerv Syst"},{"key":"R18-13-20120706","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/S0306-4522(99)00557-6","volume":"96","author":"Toda","year":"2000","journal-title":"Neuroscience"},{"key":"R19-13-20120706","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1097\/00004647-200004000-00007","volume":"20","author":"Toda","year":"2000","journal-title":"J Cereb Blood Flow Metab"},{"key":"R20-13-20120706","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1161\/01.RES.72.2.470","volume":"72","author":"Nakai","year":"1993","journal-title":"Circ Res"},{"key":"R21-13-20120706","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/0168-0102(96)01063-2","volume":"25","author":"Yoshida","year":"1996","journal-title":"Neurosci Res"},{"key":"R22-13-20120706","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/S0168-0102(96)01152-2","volume":"27","author":"Yoshida","year":"1997","journal-title":"Neurosci Res"},{"key":"R23-13-20120706","first-page":"203","volume":"36","author":"Matsuo","year":"1998","journal-title":"Eur J Morphol"},{"key":"R24-13-20120706","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1111\/j.1469-7580.2005.00391.x","volume":"206","author":"Gottanka","year":"2005","journal-title":"J Anat"},{"key":"R25-13-20120706","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/S0891-0618(01)00125-9","volume":"22","author":"Cheng","year":"2001","journal-title":"J Chem Neuroanat"},{"key":"R26-13-20120706","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.brainres.2004.06.010","volume":"1020","author":"Mizuta","year":"2004","journal-title":"Brain Res"},{"key":"R27-13-20120706","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1016\/0030-4220(93)90043-4","volume":"76","author":"Huckabee","year":"1993","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"R28-13-20120706","first-page":"H969","volume":"251","author":"Faraci","year":"1986","journal-title":"Am J Physiol"},{"key":"R29-13-20120706","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/S0304-3940(97)13360-2","volume":"222","author":"Yoshida","year":"1997","journal-title":"Neurosci Lett"},{"key":"R30-13-20120706","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1679\/aohc.59.491","volume":"59","author":"Hu","year":"1996","journal-title":"Arch Histol Cytol"},{"key":"R31-13-20120706","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1007\/BF00571878","volume":"99","author":"Kummer","year":"1993","journal-title":"Histochemistry"},{"key":"R32-13-20120706","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/S0306-3623(01)00103-3","volume":"35","author":"Koss","year":"2000","journal-title":"Gen Pharmacol"},{"key":"R33-13-20120706","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1006\/niox.2001.0346","volume":"5","author":"Roberts","year":"2001","journal-title":"Nitric Oxide"},{"key":"R34-13-20120706","doi-asserted-by":"crossref","first-page":"2211","DOI":"10.1161\/CIRCULATIONAHA.107.742692","volume":"117","author":"Nakata","year":"2008","journal-title":"Circulation"},{"key":"R35-13-20120706","first-page":"366","volume":"38","author":"Schachter","year":"1992","journal-title":"Agents Actions Suppl"},{"key":"R36-13-20120706","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/0014-2999(94)90318-2","volume":"261","author":"Modin","year":"1994","journal-title":"Eur J Pharmacol"},{"key":"R37-13-20120706","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1152\/japplphysiol.00992.2002","volume":"95","author":"Takor","year":"2003","journal-title":"J Appl Physiol"},{"key":"R38-13-20120706","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1113\/expphysiol.1996.sp003939","volume":"81","author":"Edwards","year":"1996","journal-title":"Exp Physiol"},{"key":"R39-13-20120706","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1113\/expphysiol.1997.sp004067","volume":"82","author":"Tobin","year":"1997","journal-title":"Exp Physiol"},{"key":"R40-13-20120706","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1113\/expphysiol.2005.032730","volume":"91","author":"Anderson","year":"2006","journal-title":"Exp Physiol"},{"key":"R41-13-20120706","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1016\/j.archoralbio.2010.06.013","volume":"55","author":"Witcher","year":"2010","journal-title":"Arch Oral Biol"},{"key":"R42-13-20120706","doi-asserted-by":"crossref","first-page":"R18","DOI":"10.1186\/ar2609","volume":"11","author":"Berggreen","year":"2009","journal-title":"Arthritis Res Ther"},{"key":"R43-13-20120706","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/0306-4522(92)90351-2","volume":"48","author":"Grozdanovic","year":"1992","journal-title":"Neuroscience"},{"key":"R44-13-20120706","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/0304-3940(95)11594-M","volume":"192","author":"Lohinai","year":"1995","journal-title":"Neurosci Lett"},{"key":"R45-13-20120706","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1002\/(SICI)1097-0029(19960901)35:1<32::AID-JEMT4>3.0.CO;2-U","volume":"35","author":"Soinila","year":"1996","journal-title":"Microsc Res Tech"},{"key":"R46-13-20120706","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1007\/s00360-004-0448-y","volume":"174","author":"Yamamoto","year":"2004","journal-title":"J Comp Physiol B"},{"key":"R47-13-20120706","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1016\/S0022-3565(24)38055-3","volume":"288","author":"Okamura","year":"1999","journal-title":"J Pharmacol Exp Ther"},{"key":"R48-13-20120706","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1620\/tjem.191.59","volume":"191","author":"Suzuki","year":"2000","journal-title":"Tohoku J Exp Med"},{"key":"R49-13-20120706","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1007\/s00360-007-0222-z","volume":"178","author":"Watanabe","year":"2008","journal-title":"J Comp Physiol B"},{"key":"R50-13-20120706","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/0014-2999(93)90205-V","volume":"241","author":"Kerezoudis","year":"1993","journal-title":"Eur J Pharmacol"},{"key":"R51-13-20120706","doi-asserted-by":"crossref","first-page":"S33","DOI":"10.1016\/S0003-9969(99)90012-2","volume":"44","author":"Feher","year":"1999","journal-title":"Arch Oral Biol"},{"key":"R52-13-20120706","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S0304-3940(97)00319-4","volume":"227","author":"Lohinai","year":"1997","journal-title":"Neurosci Lett"},{"key":"R53-13-20120706","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1007\/BF02576398","volume":"194","author":"Fazekas","year":"1994","journal-title":"Res Exp Med (Berl)"},{"key":"R54-13-20120706","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/0378-5955(96)00102-5","volume":"100","author":"Vass","year":"1996","journal-title":"Hear Res"},{"key":"R55-13-20120706","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/0378-5955(95)00127-4","volume":"89","author":"Vass","year":"1995","journal-title":"Hear Res"},{"key":"R56-13-20120706","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1113\/jphysiol.2003.050633","volume":"552","author":"Dux","year":"2003","journal-title":"J Physiol"},{"key":"R57-13-20120706","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1067\/moe.2001.117806","volume":"92","author":"Verdickt","year":"2001","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"R58-13-20120706","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1177\/154405910308200412","volume":"82","author":"Kemppainen","year":"2003","journal-title":"J Dent Res"},{"key":"R59-13-20120706","first-page":"253","volume":"23","author":"Boudreau","year":"2009","journal-title":"J Orofac Pain"},{"key":"R60-13-20120706","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1124\/jpet.107.133868","volume":"325","author":"Van der Schueren","year":"2008","journal-title":"J Pharmacol Exp Ther"},{"key":"R61-13-20120706","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1111\/j.1365-2125.2009.03543.x","volume":"69","author":"Sinclair","year":"2010","journal-title":"Br J Clin Pharmacol"},{"key":"R62-13-20120706","first-page":"S92","volume":"93","author":"Chularojmontri","year":"2010","journal-title":"J Med Assoc Thai"},{"key":"R63-13-20120706","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.cmet.2010.05.015","volume":"12","author":"Yang","year":"2010","journal-title":"Cell Metab"},{"key":"R64-13-20120706","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1038\/sj.bjp.0702843","volume":"128","author":"Ayajiki","year":"1999","journal-title":"Br J Pharmacol"},{"key":"R65-13-20120706","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1291\/hypres.26.237","volume":"26","author":"Ayajiki","year":"2004","journal-title":"Hypertens Res"},{"key":"R66-13-20120706","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1007\/s10266-005-0050-0","volume":"93","author":"Scardina","year":"2005","journal-title":"Odontology"},{"key":"R67-13-20120706","doi-asserted-by":"crossref","first-page":"1656","DOI":"10.1161\/01.STR.29.8.1656","volume":"29","author":"Iida","year":"1998","journal-title":"Stroke"},{"key":"R68-13-20120706","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1016\/j.lfs.2005.07.004","volume":"78","author":"Iida","year":"2006","journal-title":"Life Sci"},{"key":"R69-13-20120706","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1254\/jphs.11187FP","volume":"118","author":"Shimosato","year":"2012","journal-title":"J Pharmacol Sci"},{"key":"R70-13-20120706","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1016\/S0003-9969(96)00030-1","volume":"41","author":"Lohinai","year":"1996","journal-title":"Arch Oral Biol"},{"key":"R71-13-20120706","first-page":"139","volume":"86","author":"Vag","year":"1999","journal-title":"Acta Physiol Hung"},{"key":"R72-13-20120706","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1007\/s004330050094","volume":"198","author":"Vag","year":"1998","journal-title":"Res Exp Med (Berl)"},{"key":"R73-13-20120706","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1097\/HJH.0b013e328341d19e","volume":"29","author":"Toda","year":"2011","journal-title":"J Hypertens"},{"key":"R74-13-20120706","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1113\/eph8702330","volume":"87","author":"Vag","year":"2002","journal-title":"Exp Physiol"},{"key":"R75-13-20120706","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S1566-0702(02)00139-X","volume":"100","author":"Tobin","year":"2002","journal-title":"Auton Neurosci"},{"key":"R76-13-20120706","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1113\/jphysiol.1997.sp021871","volume":"498","author":"Toda","year":"1997","journal-title":"J Physiol"},{"key":"R77-13-20120706","doi-asserted-by":"crossref","first-page":"1372","DOI":"10.1016\/S0006-291X(05)80034-8","volume":"184","author":"Mayhan","year":"1992","journal-title":"Biochem Biophys Res Commun"},{"key":"R78-13-20120706","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1111\/j.1476-5381.1994.tb17020.x","volume":"113","author":"Hall","year":"1994","journal-title":"Br J Pharmacol"},{"key":"R79-13-20120706","first-page":"H1222","volume":"280","author":"Figueroa","year":"2001","journal-title":"Am J Physiol"},{"key":"R80-13-20120706","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1113\/jphysiol.2002.021972","volume":"544","author":"Figueroa","year":"2002","journal-title":"J Physiol"},{"key":"R81-13-20120706","first-page":"H1931","volume":"288","author":"Colantuoni","year":"2005","journal-title":"Am J Physiol"},{"key":"R82-13-20120706","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1080\/10739680600885210","volume":"13","author":"Kim","year":"2006","journal-title":"Microcirculation"},{"key":"R83-13-20120706","first-page":"H2337","volume":"272","author":"Mayhan","year":"1997","journal-title":"Am J Physiol"},{"key":"R84-13-20120706","doi-asserted-by":"crossref","first-page":"1292","DOI":"10.1152\/jappl.1998.85.4.1292","volume":"85","author":"Mayhan","year":"1998","journal-title":"J Appl Physiol"},{"key":"R85-13-20120706","doi-asserted-by":"crossref","first-page":"1829","DOI":"10.1016\/S0024-3205(99)00434-8","volume":"65","author":"Mayhan","year":"1999","journal-title":"Life Sci"},{"key":"R86-13-20120706","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1007\/0-387-26206-7_4","volume":"566","author":"Bertuglia","year":"2005","journal-title":"Adv Exp Med Biol"},{"key":"R87-13-20120706","first-page":"H1914","volume":"294","author":"Bertuglia","year":"2008","journal-title":"Am J Physiol"},{"key":"R88-13-20120706","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1006\/mvre.2000.2250","volume":"60","author":"Duran","year":"2000","journal-title":"Microvasc Res"},{"key":"R89-13-20120706","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/S0741-5214(95)70056-0","volume":"22","author":"Noel","year":"1995","journal-title":"J Vasc Surg"},{"key":"R90-13-20120706","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1177\/00220345950740081101","volume":"74","author":"Lohinai","year":"1995","journal-title":"J Dent Res"},{"key":"R91-13-20120706","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.1177\/00220345990780090801","volume":"78","author":"Berggreen","year":"1999","journal-title":"J Dent Res"},{"key":"R92-13-20120706","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1046\/j.1365-201X.1996.69319000.x","volume":"158","author":"Olgart","year":"1996","journal-title":"Acta Physiol Scand"},{"key":"R93-13-20120706","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1016\/j.lfs.2005.03.013","volume":"77","author":"Kispelyi","year":"2005","journal-title":"Life Sci"},{"key":"R94-13-20120706","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1179\/135100002125000839","volume":"7","author":"Omori","year":"2002","journal-title":"Redox Rep"},{"key":"R95-13-20120706","doi-asserted-by":"crossref","first-page":"1518","DOI":"10.1902\/jop.2009.080651","volume":"80","author":"Gyurkovics","year":"2008","journal-title":"J Periodontol"},{"key":"R96-13-20120706","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/s007840050108","volume":"4","author":"Ozmeric","year":"2000","journal-title":"Clin Oral Investig"},{"key":"R97-13-20120706","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1016\/j.atherosclerosis.2009.03.037","volume":"206","author":"Higashi","year":"2009","journal-title":"Atherosclerosis"},{"key":"R98-13-20120706","doi-asserted-by":"crossref","first-page":"1929","DOI":"10.1097\/HJH.0b013e32832e8ddf","volume":"27","author":"Toda","year":"2009","journal-title":"J Hypertens"},{"key":"R99-13-20120706","first-page":"148","volume":"7","author":"Toda","year":"1992","journal-title":"News Physiol Sci"}],"container-title":["Journal of Cardiovascular Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.1097\/FJC.0b013e318252452a","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T16:28:07Z","timestamp":1786033687000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00005344-201207000-00013"}},"subtitle":[""],"short-title":[],"issued":{"date-parts":[[2012,7]]},"references-count":99,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.1097\/fjc.0b013e318252452a","relation":{},"ISSN":["0160-2446"],"issn-type":[{"value":"0160-2446","type":"print"}],"subject":[],"published":{"date-parts":[[2012,7]]}}}