{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:28:44Z","timestamp":1786120124608,"version":"build-2736575974"},"reference-count":7,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,3]]},"DOI":"10.1097\/fpc.0b013e32835de25e","type":"journal-article","created":{"date-parts":[[2013,1,3]],"date-time":"2013-01-03T09:06:53Z","timestamp":1357204013000},"page":"175-179","source":"Crossref","is-referenced-by-count":6,"title":["Effect of HNF4\u03b1 genetic polymorphism G60D on the pharmacokinetics of CYP2D6 substrate tolterodine in healthy Korean individuals"],"prefix":"10.1097","volume":"23","author":[{"given":"Fen","family":"Jiang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang-Woo","family":"Yeo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang-Seop","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min-Kyung","family":"Oh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jong-Lyul","family":"Ghim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji-Hong","family":"Shon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ho-Sook","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eun-Young","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong-Hyun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae-Gook","family":"Shin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-9-20210213","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1677\/jme.0.0270011","article-title":"Mutations in the human genes encoding the transcription factors of the hepatocyte nuclear factor (HNF)1 and HNF4 families: functional and pathological consequences.","volume":"27","author":"Ryffel","year":"2001","journal-title":"J Mol Endocrinol"},{"key":"R3-9-20210213","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1002\/hep.22396","article-title":"Genetic polymorphism of hepatocyte nuclear factor-4alpha influences human cytochrome P450 2D6 activity.","volume":"48","author":"Lee","year":"2008","journal-title":"Hepatology"},{"key":"R4-9-20210213","doi-asserted-by":"crossref","first-page":"1456","DOI":"10.1124\/dmd.110.033407","article-title":"Effect of the CYP2D610 genotype on tolterodine pharmacokinetics.","volume":"38","author":"Oishi","year":"2010","journal-title":"Drug Metab Dispos"},{"key":"R7-9-20210213","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1046\/j.1365-2125.1999.00053.x","article-title":"Ketoconazole inhibits the metabolism of tolterodine in subjects with deficient CYP2D6 activity.","volume":"48","author":"Brynne","year":"1999","journal-title":"Br J Clin Pharmacol"},{"key":"R8-9-20210213","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1097\/00008571-200007000-00006","article-title":"Effect of gender, sex hormones, time variables and physiological urinary pH on apparent CYP2D6 activity as assessed by metabolic ratios of marker substrates.","volume":"10","author":"Labbe","year":"2000","journal-title":"Pharmacogenetics"},{"key":"R9-9-20210213","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1038\/sj.clpt.6100406","article-title":"The CYP2D6 activity score: translating genotype information into a qualitative measure of phenotype.","volume":"83","author":"Gaedigk","year":"2008","journal-title":"Clin Pharmacol Ther"},{"key":"R10-9-20210213","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1124\/dmd.111.040329","article-title":"In silico and in vitro identification of microRNAs that regulate hepatic nuclear factor 4alpha expression.","volume":"40","author":"Ramamoorthy","year":"2012","journal-title":"Drug Metab Dispos"}],"container-title":["Pharmacogenetics and Genomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/01213011-201303000-00009","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T20:14:30Z","timestamp":1786047270000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/01213011-201303000-00009"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,3]]},"references-count":7,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2013]]}},"URL":"https:\/\/doi.org\/10.1097\/fpc.0b013e32835de25e","relation":{},"ISSN":["1744-6872"],"issn-type":[{"value":"1744-6872","type":"print"}],"subject":[],"published":{"date-parts":[[2013,3]]}}}