{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T16:59:48Z","timestamp":1791910788152,"version":"4.3.4"},"reference-count":16,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,6]]},"DOI":"10.1097\/ftd.0000000000000003","type":"journal-article","created":{"date-parts":[[2013,12,4]],"date-time":"2013-12-04T09:41:25Z","timestamp":1386150085000},"page":"278-287","source":"Crossref","is-referenced-by-count":19,"title":["Low but Inducible Contribution of Renal Elimination to Clearance of Propylene Glycol in Preterm and Term Neonates"],"prefix":"10.1097","volume":"36","author":[{"given":"Roosmarijn F. W.","family":"De Cock","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karel","family":"Allegaert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie","family":"Vanhaesebrouck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"de Hoon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rene","family":"Verbesselt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meindert","family":"Danhof","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherijne A. J.","family":"Knibbe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-2-20210129","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1111\/j.1525-139X.2007.00280.x","article-title":"Recognition, treatment, and prevention of propylene glycol toxicity.","volume":"20","author":"Zar","year":"2007","journal-title":"Semin Dial"},{"key":"R2-2-20210129","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1097\/PCC.0b013e31819a383c","article-title":". Exposure to the pharmaceutical excipients benzyl alcohol and propylene glycol among critically ill neonates.","volume":"10","author":"Shehab","year":"2009","journal-title":"Pediatr Crit Care Med"},{"key":"R3-2-20210129","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1136\/adc.2010.190330","article-title":". Prospective assessment of short-term propylene glycol tolerance in neonates.","volume":"95","author":"Allegaert","year":"2010","journal-title":"Arch Dis Child"},{"key":"R4-2-20210129","first-page":"268","article-title":"American Academy of Pediatrics Committee on Drugs.","volume":"99","year":"1997","journal-title":"Pediatrics"},{"key":"R7-2-20210129","doi-asserted-by":"crossref","first-page":"F392","DOI":"10.1136\/adc.2009.160192","article-title":"Safety of inert additives or excipients in paediatric medicines.","volume":"94","author":"Nahata","year":"2009","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"R8-2-20210129","doi-asserted-by":"crossref","first-page":"1674","DOI":"10.1378\/chest.128.3.1674","article-title":". Propylene glycol toxicity: a severe iatrogenic illness in ICU patients receiving IV benzodiazepines: a case series and prospective, observational pilot study.","volume":"128","author":"Wilson","year":"2005","journal-title":"Chest"},{"key":"R9-2-20210129","doi-asserted-by":"crossref","first-page":"2752","DOI":"10.1097\/00003246-200212000-00021","article-title":". Propylene glycol accumulation associated with continuous infusion of lorazepam in pediatric intensive care patients.","volume":"30","author":"Chicella","year":"2002","journal-title":"Crit Care Med"},{"key":"R10-2-20210129","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1542\/peds.72.3.353","article-title":". Hyperosmolality in small infants due to propylene glycol.","volume":"72","author":"Glasgow","year":"1983","journal-title":"Pediatrics"},{"key":"R11-2-20210129","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1002\/jps.2600740815","article-title":"Pharmacokinetics of propylene glycol in humans during multiple dosing regimens.","volume":"74","author":"Yu","year":"1985","journal-title":"J Pharm Sci"},{"key":"R12-2-20210129","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1097\/00007691-198709000-00001","article-title":". Propylene glycol pharmacokinetics and effects after intravenous infusion in humans.","volume":"9","author":"Speth","year":"1987","journal-title":"Ther Drug Monit"},{"key":"R14-2-20210129","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1203\/00006450-196705000-00001","article-title":"Development of alcohol dehydrogenase activity in the human liver.","volume":"1","author":"Pikkarainen","year":"1967","journal-title":"Pediatr Res"},{"key":"R15-2-20210129","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1111\/j.1365-2125.2012.04312.x","article-title":". Developmental pharmacokinetics of propylene glycol in preterm and term neonates.","volume":"75","author":"De Cock","year":"2013","journal-title":"Br J Clin Pharmacol"},{"key":"R18-2-20210129","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1038\/sj.clpt.6100241","article-title":"Diagnosing model diagnostics.","volume":"82","author":"Karlsson","year":"2007","journal-title":"Clin Pharmacol Ther"},{"key":"R19-2-20210129","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1007\/s11095-010-0333-1","article-title":". Systematic evaluation of the descriptive and predictive performance of paediatric morphine population models.","volume":"28","author":"Krekels","year":"2011","journal-title":"Pharm Res"},{"key":"R21-2-20210129","doi-asserted-by":"crossref","first-page":"2036","DOI":"10.1007\/s11095-006-9067-5","article-title":". Metrics for external model evaluation with an application to the population pharmacokinetics of gliclazide.","volume":"23","author":"Brendel","year":"2006","journal-title":"Pharm Res"},{"key":"R22-2-20210129","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.cmpb.2007.12.002","article-title":"Computing normalised prediction distribution errors to evaluate nonlinear mixed-effect models: the npde add-on package for R.","volume":"90","author":"Comets","year":"2008","journal-title":"Comput Methods Programs Biomed"}],"container-title":["Therapeutic Drug Monitoring"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/FTD.0000000000000003","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,18]],"date-time":"2022-03-18T16:32:43Z","timestamp":1647621163000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00007691-201406000-00002"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,6]]},"references-count":16,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2014]]}},"URL":"https:\/\/doi.org\/10.1097\/ftd.0000000000000003","relation":{},"ISSN":["0163-4356"],"issn-type":[{"value":"0163-4356","type":"print"}],"subject":[],"published":{"date-parts":[[2014,6]]}}}