{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T15:41:05Z","timestamp":1790869265978,"version":"4.1.0"},"reference-count":28,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2009,10]]},"DOI":"10.1097\/ftd.0b013e3181affd6d","type":"journal-article","created":{"date-parts":[[2009,9,22]],"date-time":"2009-09-22T07:18:02Z","timestamp":1253603882000},"page":"557-565","source":"Crossref","is-referenced-by-count":7,"title":["Pharmacokinetic-Pharmacodynamic Modeling of Manganese After a Single Intravenous Infusion of Mangafodipir in Patients With Acute Alcoholic Hepatitis"],"prefix":"10.1097","volume":"31","author":[{"given":"D\u00e9borah","family":"Hirt","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Philippe","family":"Richardet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sa\u00efk","family":"Urien","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00ebl","family":"Poupon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Sogni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fr\u00e9d\u00e9ric","family":"Batteux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexis","family":"Laurent","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvana","family":"Pavlovic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcel","family":"Debray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Marc","family":"Treluyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernard","family":"Weill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-5-20210129","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1021\/ic00302a019","article-title":"Manganese (II) N,N-dipyridoxylethylenediamine-N,N-diacetate 5,5bis(phosphate). Synthesis and characterization of a paramagnetic chelate for magnetic resonance imaging enhancement.","volume":"28","author":"Rocklage","year":"1989","journal-title":"Inorg Chem"},{"key":"R2-5-20210129","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1080\/02841859709172411","article-title":"Physicochemical characterisation of mangafodipir trisodium.","volume":"38","author":"Tirkkonen","year":"1997","journal-title":"Acta Radiol"},{"key":"R3-5-20210129","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1016\/S0731-7085(96)01945-0","article-title":"Mangafodipir trisodium injection, a new contrast medium for magnetic resonance imaging: detection and quantitation of the parent compound MnDPDP and metabolites in human plasma by high performance liquid chromatography.","volume":"15","author":"Toft","year":"1997","journal-title":"J Pharm Biomed Anal"},{"key":"R4-5-20210129","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1007\/BF03189786","article-title":"Metabolism of mangafodipir trisodium (MnDPDP), a new contrast medium for magnetic resonance imaging, in beagle dogs.","volume":"22","author":"Toft","year":"1997","journal-title":"Eur J Drug Metab Pharmacokinet"},{"key":"R5-5-20210129","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0304-4165(76)90218-X","article-title":"Manganese metabolism in cows and goats.","volume":"444","author":"Gibbons","year":"1976","journal-title":"Biochim Biophys Acta"},{"key":"R6-5-20210129","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1080\/02841859709172401","article-title":"Plasma pharmacokinetics, tissue distribution and excretion of MnDPDP in the rat and dog after intravenous administration.","volume":"38","author":"Hustvedt","year":"1997","journal-title":"Acta Radiol"},{"key":"R7-5-20210129","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1080\/02841859709172402","article-title":"Comparison of manganese biodistribution and MR contrast enhancement in rats after intravenous injection of MnDPDP and MnCl2.","volume":"38","author":"Ni","year":"1997","journal-title":"Acta Radiol"},{"key":"R8-5-20210129","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/S0165-6147(99)01336-X","article-title":"Metalloporphyrin class of therapeutic catalytic antioxidants.","volume":"20","author":"Patel","year":"1999","journal-title":"Trends Pharmacol Sci"},{"key":"R9-5-20210129","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1126\/science.286.5438.304","article-title":"A nonpeptidyl mimic of superoxide dismutase with therapeutic activity in rats.","volume":"286","author":"Salvemini","year":"1999","journal-title":"Science"},{"key":"R10-5-20210129","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S0300-483X(00)00306-1","article-title":"Effects of antioxidant enzymes in the molecular control of reactive oxygen species toxicology.","volume":"153","author":"Mates","year":"2000","journal-title":"Toxicology"},{"key":"R11-5-20210129","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1053\/jhep.2001.24267","article-title":"Detoxification of reactive oxygen species by a nonpeptidyl mimic of superoxide dismutase cures acetaminophen-induced acute liver failure in the mouse.","volume":"33","author":"Ferret","year":"2001","journal-title":"Hepatology"},{"key":"R12-5-20210129","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1053\/gast.2001.29590","article-title":"The superoxide dismutase mimetic MnTBAP prevents Fas-induced acute liver failure in the mouse.","volume":"121","author":"Malassagne","year":"2001","journal-title":"Gastroenterology"},{"key":"R13-5-20210129","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1111\/j.1478-3231.1999.tb00077.x","article-title":"The significance of apoptosis in the liver.","volume":"19","author":"Benedetti","year":"1999","journal-title":"Liver"},{"key":"R14-5-20210129","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1002\/hep.510250219","article-title":"Oxidative stress-mediated apoptosis of hepatocytes exposed to acute ethanol intoxication.","volume":"25","author":"Kurose","year":"1997","journal-title":"Hepatology"},{"key":"R15-5-20210129","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/S0168-8278(01)00289-6","article-title":"Corticosteroids improve short-term survival in patients with severe alcoholic hepatitis (AH): individual data analysis of the last three randomized placebo controlled double blind trials of corticosteroids in severe AH.","volume":"36","author":"Mathurin","year":"2002","journal-title":"J Hepatol"},{"key":"R16-5-20210129","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/0016-5085(78)90401-8","article-title":"Corticosteroid therapy of alcoholic hepatitis.","volume":"75","author":"Maddrey","year":"1978","journal-title":"Gastroenterology"},{"key":"R17-5-20210129","doi-asserted-by":"crossref","first-page":"685","DOI":"10.7326\/0003-4819-110-9-685","article-title":"Methylprednisolone therapy in patients with severe alcoholic hepatitis: a randomized multicenter trial.","volume":"110","author":"Carithers","year":"1989","journal-title":"Ann Intern Med"},{"key":"R18-5-20210129","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0261-5614(97)80022-2","article-title":"ESPEN guidelines for nutrition in liver disease and transplantation.","volume":"16","author":"Plauth","year":"1997","journal-title":"Clin Nutr"},{"key":"R20-5-20210129","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/0003-2697(71)90370-8","article-title":"Superoxide dismutase: improved assays and an assay applicable to acrylamide gels.","volume":"44","author":"Beauchamp","year":"1971","journal-title":"Anal Biochem"},{"key":"R21-5-20210129","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S0076-6879(84)05016-3","article-title":"Catalase in vitro.","volume":"105","author":"Aebi","year":"1984","journal-title":"Methods Enzymol"},{"key":"R23-5-20210129","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1080\/10618600.1996.10474713","article-title":"R: a language for data analysis and graphics.","volume":"5","author":"Ihaka","year":"1996","journal-title":"J Comput Graph Stat"},{"key":"R24-5-20210129","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/S0169-2607(98)00098-4","article-title":"A procedure for generating bootstrap samples for the validation of nonlinear mixed-effects population models.","volume":"59","author":"Parke","year":"1999","journal-title":"Comput Methods Programs Biomed"},{"key":"R26-5-20210129","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1093\/ajcn\/49.1.170","article-title":"Manganese retention in man: a method for estimating manganese absorption in man.","volume":"49","author":"Davidsson","year":"1989","journal-title":"Am J Clin Nutr"},{"key":"R27-5-20210129","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1093\/toxsci\/54.2.295","article-title":"Comparative toxicokinetics of manganese chloride and methylcyclopentadienyl manganese tricarbonyl (MMT) in Sprague-Dawley rats.","volume":"54","author":"Zheng","year":"2000","journal-title":"Toxicol Sci"},{"key":"R28-5-20210129","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1080\/02841859709172400","article-title":"Metabolism and pharmacokinetics of MnDPDP in man.","volume":"38","author":"Toft","year":"1997","journal-title":"Acta Radiol"},{"key":"R29-5-20210129","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1067\/mcp.2001.118244","article-title":"Pharmacodynamic modeling of time-dependent transduction systems.","volume":"70","author":"Mager","year":"2001","journal-title":"Clin Pharmacol Ther"},{"key":"R30-5-20210129","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1016\/j.hep.2003.09.038","article-title":"Early change in bilirubin concentrations is an important prognostic factor in severe alcoholic hepatitis treated with prednisolone.","volume":"38","author":"Mathurin","year":"2003","journal-title":"Hepatology"},{"key":"R31-5-20210129","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1002\/cpt196910122","article-title":"Kinetics of pharmacologic effects in man: the anticoagulant action of warfarin.","volume":"10","author":"Nagashima","year":"1969","journal-title":"Clin Pharmacol Ther"}],"container-title":["Therapeutic Drug Monitoring"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/FTD.0b013e3181affd6d","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,12]],"date-time":"2025-02-12T08:42:13Z","timestamp":1739349733000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00007691-200910000-00005"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,10]]},"references-count":28,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2009]]}},"URL":"https:\/\/doi.org\/10.1097\/ftd.0b013e3181affd6d","relation":{},"ISSN":["0163-4356"],"issn-type":[{"value":"0163-4356","type":"print"}],"subject":[],"published":{"date-parts":[[2009,10]]}}}