{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:05:45Z","timestamp":1786118745654,"version":"build-2736575974"},"reference-count":50,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2007,4]]},"DOI":"10.1097\/gco.0b013e32807fb199","type":"journal-article","created":{"date-parts":[[2007,3,12]],"date-time":"2007-03-12T02:53:11Z","timestamp":1173667991000},"page":"113-119","source":"Crossref","is-referenced-by-count":34,"title":["Reproductive outcomes after in-vitro fertilization"],"prefix":"10.1097","volume":"19","author":[{"given":"Neelanjana","family":"Mukhopadhaya","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabaratnam","family":"Arulkumaran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-4-20210129","doi-asserted-by":"crossref","first-page":"1680","DOI":"10.1093\/humrep\/del075","article-title":"Assisted reproductive technology in Europe, 2002: results generated from European registers by ESHRE","volume":"21","author":"Andersen","year":"2006","journal-title":"Hum Reprod"},{"key":"R2-4-20210129","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1136\/bmj.291.6503.1160","article-title":"High incidence of preterm births and early losses in pregnancy after in vitro fertilisation.","volume":"291","year":"1985","journal-title":"BMJ"},{"key":"R3-4-20210129","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1016\/S0022-3476(95)70175-3","article-title":"Maternal and neonatal morbidity associated with in vitro fertilisation","volume":"127","author":"Tallo","year":"1995","journal-title":"J Pediatr"},{"key":"R4-4-20210129","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/S0015-0282(98)00160-5","article-title":"Obstetric outcome of singleton pregnancies conceived by in vitro fertilisation and ovulation induction compared with those conceived spontaneously","volume":"70","author":"Maman","year":"1998","journal-title":"Fertil Steril"},{"key":"R5-4-20210129","doi-asserted-by":"crossref","first-page":"1755","DOI":"10.1093\/humrep\/17.7.1755","article-title":"Obstetric outcome among women with unexplained infertility after IVF: a matched case control study","volume":"17","author":"Isaksson","year":"2002","journal-title":"Hum Reprod"},{"key":"R6-4-20210129","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1007\/s10815-004-8760-8","article-title":"A meta-analysis of controlled studies comparing major malformations rates in IVF and ICSI infants with naturally conceived children","volume":"21","author":"Rimm","year":"2004","journal-title":"J Assist Reprod Genet"},{"issue":"Suppl 1","key":"R7-4-20210129","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1111\/j.1471-0528.2005.00598.x","article-title":"Impact of medically assisted fertility on preterm birth","volume":"112","author":"Filicori","year":"2005","journal-title":"BJOG"},{"key":"R8-4-20210129","doi-asserted-by":"crossref","first-page":"F10","DOI":"10.1136\/fn.75.1.F10","article-title":"Recent trends in the incidence of multiple births associated mortality in England and Wales","volume":"75","author":"Dunn","year":"1996","journal-title":"Arch Dis Child"},{"key":"R9-4-20210129","doi-asserted-by":"crossref","first-page":"1579","DOI":"10.1016\/S0140-6736(99)04345-7","article-title":"Deliveries and children born after in-vitro fertilization in Sweden 1982\u201395: a retrospective cohort study","volume":"254","author":"Bergh","year":"1999","journal-title":"Lancet"},{"key":"R10-4-20210129","first-page":"1313","article-title":"Reducing the risk of multiple births by transfer of two embryos after in vitro fertilization","volume":"341","author":"Templeton","year":"1999","journal-title":"N Engl J Med"},{"key":"R11-4-20210129","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/j.fertnstert.2005.02.020","article-title":"One last chance for pregnancy: a review of 2,705 in-vitro fertilisation cycles initiated in women age 40 years and above","volume":"84","author":"Klipstein","year":"2005","journal-title":"Fertil Steril"},{"key":"R12-4-20210129","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1007\/s10815-005-4919-1","article-title":"Lower embryonic loss rates among twin gestations following assisted reproduction","volume":"22","author":"La Sala","year":"2005","journal-title":"J Assist Reprod Genet"},{"key":"R13-4-20210129","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/S1472-6483(10)60981-9","article-title":"Early pregnancy loss is significantly higher after day 3 single embryo transfer than after day 5 single blastocyst transfer in GnRH antagonist stimulated cycles","volume":"12","author":"Papanikolaou","year":"2006","journal-title":"Reprod Biomed Online"},{"key":"R14-4-20210129","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1016\/j.fertnstert.2005.10.014","article-title":"Preimplantation genetic diagnosis significantly reduces pregnancy loss in infertile couples: a multicenter study","volume":"85","author":"Munne","year":"2006","journal-title":"Fertil Steril"},{"key":"R16-4-20210129","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1097\/01.AOG.0000196503.78126.62","article-title":"Ectopic pregnancy risk with assisted reproductive technology procedures","volume":"107","author":"Clayton","year":"2006","journal-title":"Obstet Gynecol"},{"key":"R17-4-20210129","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.1016\/S0015-0282(98)00350-1","article-title":"Obstetric outcome of in vitro fertilized pregnancies complicated by severe ovarian hyperstimulation syndrome: a multicenter study","volume":"70","author":"Abramov","year":"1998","journal-title":"Fertil Steril"},{"key":"R18-4-20210129","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1093\/humrep\/deh713","article-title":"Outcome of pregnancies complicated by severe ovarian hyperstimulation syndrome (OHSS): a follow up beyond the second trimester","volume":"20","author":"Wiser","year":"2005","journal-title":"Hum Reprod"},{"key":"R19-4-20210129","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1093\/humrep\/dei501","article-title":"A systematic review and metaanalysis of randomised controlled trials on metformin co-administration during gonadotrophin ovulation induction or IVF in women with polycystic ovary syndrome","volume":"21","author":"Costello","year":"2006","journal-title":"Hum Reprod"},{"key":"R20-4-20210129","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1111\/j.1471-0528.2005.00745.x","article-title":"In vitro fertilization in Sweden: obstetric characteristics and maternal morbidity and mortality","volume":"112","author":"Kallen","year":"2005","journal-title":"BJOG"},{"key":"R21-4-20210129","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1097\/01.AOG.0000183593.24583.7c","article-title":"Assisted reproductive technology and pregnancy outcome","volume":"106","author":"Shevell","year":"2005","journal-title":"Obstet Gynecol"},{"key":"R22-4-20210129","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/S1701-2163(16)32112-0","article-title":"Pregnancy outcomes after assisted reproductive technology","volume":"28","author":"Allen","year":"2006","journal-title":"J Obstet Gynaecol Can"},{"key":"R23-4-20210129","doi-asserted-by":"crossref","first-page":"2353","DOI":"10.1093\/humrep\/del153","article-title":"Increased risk of placenta previa in pregnancies following IVF\/ICSI: a comparison of ART and non-ART pregnancies in the same mother","volume":"21","author":"Romundstad","year":"2006","journal-title":"Hum Reprod"},{"key":"R24-4-20210129","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1097\/01.AOG.0000114989.84822.51","article-title":"Perinatal outcomes in singletons following in vitro fertilization: a meta-analysis","volume":"103","author":"Jackson","year":"2004","journal-title":"Obstet Gynecol"},{"key":"R25-4-20210129","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1016\/S0002-9378(97)70017-6","article-title":"The association of placenta praevia with a history of caesarean delivery and abortion: a metaanalysis","volume":"177","author":"Ananth","year":"1997","journal-title":"Am J Obstet Gynecol"},{"key":"R26-4-20210129","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1016\/0029-7844(95)00322-I","article-title":"Singleton pregnancy after in vitro fertilization: expectations and outcome","volume":"86","author":"Verlaenen","year":"1995","journal-title":"Obstet Gynecol"},{"key":"R27-4-20210129","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1111\/j.1471-0528.2005.00565.x","article-title":"Outcomes of severe preeclampsia\/eclampsia in Yorkshire: 1999\/2003","volume":"112","author":"Tuffnell","year":"2005","journal-title":"BJOG"},{"key":"R28-4-20210129","doi-asserted-by":"crossref","first-page":"1332","DOI":"10.1136\/bmj.318.7194.1332","article-title":"Fortnightly review: management of hypertension in pregnancy","volume":"318","author":"Magee","year":"1999","journal-title":"BMJ"},{"key":"R29-4-20210129","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1016\/S0002-9378(11)91589-0","article-title":"Obstetric outcome of in vitro fertilization pregnancies compared with normally conceived pregnancies","volume":"167","author":"Tan","year":"1992","journal-title":"Am J Obstet Gynecol"},{"key":"R30-4-20210129","doi-asserted-by":"crossref","first-page":"2948","DOI":"10.1093\/humrep\/del155","article-title":"Decreased ovarian reserve related to preeclampsia in IVF\/ICSI pregnancies","volume":"21","author":"Woldringh","year":"2006","journal-title":"Hum Reprod"},{"key":"R31-4-20210129","doi-asserted-by":"crossref","first-page":"2080","DOI":"10.1016\/S0140-6736(00)05180-1","article-title":"Outcome in the second year of life after in vitro fertilization by intracytoplasmic injection: a UK based case-control study","volume":"357","author":"Sutcliffe","year":"2001","journal-title":"Lancet"},{"key":"R32-4-20210129","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1067\/S0002-9378(03)00485-X","article-title":"Pregnancy outcome in spontaneous twins versus twins who were conceived through in vitro fertilization","volume":"189","author":"Nassar","year":"2003","journal-title":"Am J Obstet Gynecol"},{"key":"R33-4-20210129","doi-asserted-by":"crossref","first-page":"1604","DOI":"10.1016\/j.fertnstert.2003.10.053","article-title":"Pregnancy course and outcome after intracytoplasmic sperm injection: a controlled prospective cohort study","volume":"81","author":"Katalinic","year":"2004","journal-title":"Fertil Steril"},{"key":"R34-4-20210129","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1136\/bmj.37957.560278.EE","article-title":"Perinatal outcome of singletons and twins after assisted conception: a systematic review of controlled studies","volume":"328","author":"Helmerhorst","year":"2004","journal-title":"BMJ"},{"key":"R35-4-20210129","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1016\/S0015-0282(03)00793-3","article-title":"High frequency of caesarean section, antepartum haemorrhage, placenta praevia and preterm delivery in in vitro fertilization twin pregnancies","volume":"80","author":"Smithers","year":"2003","journal-title":"Fertil Steril"},{"key":"R36-4-20210129","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/j.fertnstert.2003.10.020","article-title":"Parenting stress in first time mothers of twins and triplets conceived after in vitro fertilization","volume":"81","author":"Glazebrook","year":"2004","journal-title":"Fertil Steril"},{"key":"R37-4-20210129","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1056\/NEJMoa010035","article-title":"The risk of major birth defects after intracytoplasmic injection and in vitro fertilisation","volume":"346","author":"Hansen","year":"2002","journal-title":"N Engl J Med"},{"key":"R39-4-20210129","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.1016\/S0140-6736(02)11476-0","article-title":"Preterm delivery","volume":"360","author":"Slattery","year":"2002","journal-title":"Lancet"},{"key":"R40-4-20210129","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1016\/S0002-9378(99)70514-4","article-title":"Perinatal outcomes of pregnancies after assisted reproduction: a case-control study","volume":"181","author":"Dhont","year":"1999","journal-title":"Am J Obstet Gynecol"},{"key":"R41-4-20210129","doi-asserted-by":"crossref","first-page":"1819","DOI":"10.1093\/humrep\/15.8.1819","article-title":"Obstetric outcome of singleton pregnancies after IVF: a matched control study in four Dutch University Hospitals","volume":"15","author":"Koudstaal","year":"2000","journal-title":"Hum Reprod"},{"key":"R42-4-20210129","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1016\/0029-7844(95)00159-O","article-title":"Obstetric outcome in singleton pregnancies after assisted reproduction","volume":"86","author":"Tanbo","year":"1995","journal-title":"Obstet Gynecol"},{"key":"R43-4-20210129","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1016\/S0015-0282(97)81442-2","article-title":"Is the obstetric outcome of in vitro fertilized singleton gestations different from natural ones? A controlled study","volume":"67","author":"Reubinoff","year":"1997","journal-title":"Fertil Steril"},{"key":"R44-4-20210129","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1023\/A:1022682908307","article-title":"The incidence of major birth defects following in vitro fertilization","volume":"20","author":"Zadori","year":"2003","journal-title":"J Assist Reprod Genet"},{"key":"R46-4-20210129","doi-asserted-by":"crossref","first-page":"3332","DOI":"10.1093\/humrep\/13.12.3332","article-title":"Y chromosome deletions in azoospermic and severely oligozoospermic men undergoing intracytoplasmic sperm injection after testicular sperm extraction","volume":"13","author":"Silber","year":"1998","journal-title":"Hum Reprod"},{"key":"R47-4-20210129","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1016\/S0015-0282(00)01568-5","article-title":"Y chromosome analysis of infertile men and their sons conceived through intracytoplasmic sperm injection: vertical transmission of deletions and rarity of de novo deletions","volume":"74","author":"Cram","year":"2000","journal-title":"Fertil Steril"},{"key":"R48-4-20210129","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1086\/423902","article-title":"Beckwith-Wiedemann syndrome and IVF: a case-control study","volume":"75","author":"Halliday","year":"2004","journal-title":"Am J Hum Genet"},{"key":"R49-4-20210129","doi-asserted-by":"crossref","first-page":"1975","DOI":"10.1016\/S0140-6736(03)13592-1","article-title":"Rare congenital disorders, imprinted genes and assisted reproductive technology","volume":"361","author":"Gosden","year":"2003","journal-title":"Lancet"},{"key":"R50-4-20210129","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1111\/j.1471-0528.2006.00942.x","article-title":"Predicting the impact of in vitro fertilisation and other forms of assisted conception on perinatal and infant mortality in England and Wales: examining the role of multiplicity","volume":"113","author":"Oakley","year":"2006","journal-title":"BJOG"},{"key":"R51-4-20210129","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1136\/bmj.38751.524132.2F","article-title":"Spontaneous preterm delivery in primiparous women at low risk in Denmark: population based study","volume":"332","author":"Lanhoff-Roos","year":"2006","journal-title":"BMJ"},{"key":"R52-4-20210129","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1093\/humrep\/15.4.935","article-title":"Obstetric outcome of twin pregnancies after in-vitro fertilization: a matched control study in four Dutch university hospitals","volume":"15","author":"Koudstaal","year":"2000","journal-title":"Hum Reprod"},{"key":"R53-4-20210129","doi-asserted-by":"crossref","first-page":"757","DOI":"10.7863\/jum.2001.20.7.757","article-title":"Frequency of a monochorionic pair in multiple gestations: relationship to mode of conception","volume":"20","author":"Chow","year":"2001","journal-title":"J Ultrasound Med"}],"container-title":["Current Opinion in Obstetrics & Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.1097\/GCO.0b013e32807fb199","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T16:36:18Z","timestamp":1786034178000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00001703-200704000-00004"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,4]]},"references-count":50,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2007]]}},"URL":"https:\/\/doi.org\/10.1097\/gco.0b013e32807fb199","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.1070997.523967","asserted-by":"object"}]},"ISSN":["1040-872X"],"issn-type":[{"value":"1040-872X","type":"print"}],"subject":[],"published":{"date-parts":[[2007,4]]}}}