{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:12:53Z","timestamp":1786119173488,"version":"build-2736575974"},"reference-count":59,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2007,10]]},"DOI":"10.1097\/gco.0b013e3282efdc21","type":"journal-article","created":{"date-parts":[[2009,3,4]],"date-time":"2009-03-04T17:57:14Z","timestamp":1236189434000},"page":"464-468","source":"Crossref","is-referenced-by-count":26,"title":["Familial transmission of urogenital prolapse and incontinence"],"prefix":"10.1097","volume":"19","author":[{"given":"Christian","family":"Twiss","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veronica","family":"Triaca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Larissa V","family":"Rodr\u00edguez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-11-20210129","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1016\/S0889-8545(05)70039-5","article-title":"Epidemiology and natural history of pelvic floor dysfunction","volume":"25","author":"Bump","year":"1998","journal-title":"Obstet Gynecol Clin North Am"},{"key":"R2-11-20210129","doi-asserted-by":"crossref","first-page":"74","DOI":"10.3109\/00016349709047789","article-title":"A population study of urinary incontinence and nocturia among women aged 20\u201359 years","volume":"76","author":"Samuelsson","year":"1997","journal-title":"Acta Obstet Gynecol Scand"},{"key":"R3-11-20210129","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1136\/bmj.306.6881.832","article-title":"Urinary incontinence in the community-analysis of a MORI poll","volume":"306","author":"Broklehurst","year":"1993","journal-title":"Br Med J"},{"key":"R4-11-20210129","first-page":"66","article-title":"Prevalence of urinary incontinence associated risk factors in postmenopausal women","volume":"94","author":"Brown","year":"1999","journal-title":"Obstet Gynecol"},{"key":"R5-11-20210129","doi-asserted-by":"crossref","first-page":"2149","DOI":"10.1016\/j.ajog.2005.08.055","article-title":"Delivery mode is a major environmental determinant of stress urinary incontinence: Results of the Evanston-Northwestern Twin Sisters Study","volume":"193","author":"Goldberg","year":"2005","journal-title":"Am J Obstet Gynecol"},{"key":"R6-11-20210129","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1097\/01.AOG.0000175832.13266.bb","article-title":"Pelvic organ prolapse","volume":"106","author":"Weber","year":"2005","journal-title":"Obstet Gynecol"},{"key":"R7-11-20210129","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/S1701-2163(16)30518-7","article-title":"A review of the epidemiology and pathophysiology of pelvic floor dysfunction: Do racial differences matter?","volume":"27","author":"Kim","year":"2005","journal-title":"J Obstet Gynecol Can"},{"key":"R8-11-20210129","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1007\/s00192-005-0009-2","article-title":"Prevalence of severe pelvic organ prolapse in relation to job description and socioeconomic status: a multicenter cross-sectional study","volume":"17","author":"Woodman","year":"2006","journal-title":"Int Urogynecol J Pelvic Floor Dysfunct"},{"key":"R9-11-20210129","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1093\/occmed\/44.1.47","article-title":"Heavy lifting at work and risk of genital prolapse and herniated lumbar disc in assistant nurses","volume":"44","author":"Jorgensen","year":"1994","journal-title":"Occup Med"},{"key":"R10-11-20210129","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/S0301-2115(98)00175-4","article-title":"Reproductive factors, family history, occupation and risk of urogenital prolapse","volume":"82","author":"Chiaffarino","year":"1999","journal-title":"Eur J Obstet Gynecol Rep Biol"},{"key":"R11-11-20210129","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1001\/archinte.165.5.537","article-title":"Urinary Incontinence in US women","volume":"165","author":"Melville","year":"2005","journal-title":"Arch Int Med"},{"key":"R12-11-20210129","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1007\/s00192-006-0188-5","article-title":"Quality of life in women with stress urinary incontinence","volume":"18","author":"Tennstedt","year":"2006","journal-title":"Int Urogynecol J Pelvic Floor Dysfunct"},{"key":"R13-11-20210129","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1067\/mob.2002.123819","article-title":"Pelvic organ prolapse in the Women's Health Initiative: Gravity and gravidity","volume":"186","author":"Hendrix","year":"2002","journal-title":"Am J Obstet Gynecol"},{"key":"R14-11-20210129","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1016\/j.ajog.2004.10.602","article-title":"Pelvic Organ Support Study (POSST): The distribution, clinical definition, and epidemiologic condition of pelvic organ support defects","volume":"192","author":"Swift","year":"2005","journal-title":"Am J Obstet Gynecol"},{"key":"R15-11-20210129","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1007\/s00192-003-1073-0","article-title":"Do Asian women have less pelvic organ mobility than Caucasians?","volume":"14","author":"Dietz","year":"2003","journal-title":"Int Urogynecol J"},{"key":"R16-11-20210129","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1479-828X.1977.tb02661.x","article-title":"\u201cA Chinese anatomy\u201d \u2013 the pelvic supporting tissues of the Chinese and Occidental female compared and contrasted","volume":"17","author":"Zacharin","year":"1977","journal-title":"Aust N Z J Obstet Gynaecol"},{"key":"R17-11-20210129","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/S0002-9378(99)70203-6","article-title":"Signs of genital prolapse in a Swedish population of women 20 to 59 years of age and possible related factors","volume":"180","author":"Samuelsson","year":"1999","journal-title":"Am J Obstet Gynecol"},{"key":"R18-11-20210129","doi-asserted-by":"crossref","first-page":"1396","DOI":"10.1097\/01.AOG.0000263469.68106.90","article-title":"Symptomatic pelvic organ prolapse: prevalence and risk factors in a population-based, racially diverse cohort","volume":"109","author":"Rortveit","year":"2007","journal-title":"Obstet Gynecol"},{"key":"R19-11-20210129","first-page":"1","article-title":"Births: Final Data for 2004","volume":"55","author":"Martin","year":"2006","journal-title":"Nat Vital Stat Rep"},{"key":"R20-11-20210129","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1111\/j.1471-0528.1997.tb11536.x","article-title":"Epidemiology of genital prolapse: observations from the Oxford Family Planning Association study","volume":"104","author":"Mant","year":"1997","journal-title":"Br J Obstet Gynecol"},{"key":"R21-11-20210129","first-page":"951","article-title":"Urinary incontinence and pelvic organ prolapse in nulliparous women","volume":"92","author":"Harris","year":"1998","journal-title":"Obstet Gynecol"},{"key":"R22-11-20210129","doi-asserted-by":"crossref","first-page":"1388","DOI":"10.1097\/01.AOG.0000245784.31082.ed","article-title":"Pelvic organ prolapse in nulliparous women and their parous sisters","volume":"108","author":"Buchsbaum","year":"2006","journal-title":"Obstet Gynecol"},{"key":"R23-11-20210129","first-page":"226","article-title":"Prevalence of urinary incontinence and associated risk factors in a cohort of nuns","volume":"100","author":"Buchsbaum","year":"2002","journal-title":"Obstet Gynecol"},{"key":"R24-11-20210129","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1097\/01.AOG.0000187309.46650.b2","article-title":"Urinary incontinence in nulliparous women and their parous sisters","volume":"106","author":"Buchsbaum","year":"2005","journal-title":"Obstet Gynecol"},{"key":"R25-11-20210129","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S0301-2115(99)00002-0","article-title":"What predisposes young women to genital prolapse?","volume":"84","author":"Rinne","year":"1999","journal-title":"Eur J Obstet Gynecol Rep Biol"},{"key":"R26-11-20210129","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1007\/s00192-005-0054-x","article-title":"Familial transmission of genitovaginal prolapse","volume":"17","author":"Jack","year":"2006","journal-title":"Int Urogynecol J Pelvic Floor Dysfunct"},{"key":"R27-11-20210129","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1016\/S0002-9378(96)70437-4","article-title":"Female urinary stress incontinence\u2013 does it have a familial prevalence?","volume":"174","author":"Mushkat","year":"1996","journal-title":"Am J Obstet Gynecol"},{"key":"R28-11-20210129","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1111\/j.0001-6349.2004.00333.x","article-title":"Is stress urinary incontinence a familial condition?","volume":"83","author":"Ertunc","year":"2004","journal-title":"Acta Obstet Gynecol Scand"},{"key":"R29-11-20210129","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1136\/bmj.329.7471.889","article-title":"Familial risk of urinary incontinence in women: population based cross sectional study","volume":"329","author":"Hannestad","year":"2004","journal-title":"Br Med J"},{"key":"R30-11-20210129","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.ajog.2004.01.025","article-title":"Pelvic organ descent in young nulligravid women","volume":"191","author":"Dietz","year":"2004","journal-title":"Am J Obstet Gynecol"},{"key":"R31-11-20210129","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1375\/136905204774200532","article-title":"Genetic covariation of pelvic organ and elbow mobility in twins and their sisters","volume":"7","author":"Hansell","year":"2004","journal-title":"Twin Res"},{"key":"R32-11-20210129","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/0029-7844(94)00386-R","article-title":"Genitourinary prolapse and joint hypermobility in women","volume":"85","author":"Norton","year":"1995","journal-title":"Obstet Gynecol"},{"key":"R33-11-20210129","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1067\/mob.2000.105410","article-title":"Urinary incontinence and pelvic organ prolapse in women with Marfan's or Ehlers\u2013Danlos syndrome","volume":"182","author":"Carley","year":"2000","journal-title":"Am J Obstet Gynecol"},{"key":"R34-11-20210129","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1016\/1071-5576(94)00050-B","article-title":"Gynecologic disorders in women with ehlers-danlos syndrome","volume":"2","author":"McIntosh","year":"1995","journal-title":"J Sot Gynecol Invest"},{"key":"R35-11-20210129","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1136\/jmg.2005.039669","article-title":"The molecular genetics of Marfan syndrome and related disorders","volume":"43","author":"Robinson","year":"2006","journal-title":"J Med Genet"},{"key":"R36-11-20210129","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/S0945-053X(00)00099-8","article-title":"Genetic disorders of the elastic fiber system","volume":"19","author":"Milewicz","year":"2000","journal-title":"Matrix Biol"},{"key":"R37-11-20210129","doi-asserted-by":"crossref","first-page":"1965","DOI":"10.1016\/S0140-6736(05)67789-6","article-title":"Marfan's syndrome","volume":"366","author":"Judge","year":"2005","journal-title":"Lancet"},{"key":"R38-11-20210129","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1046\/j.1524-475X.1997.50105.x","article-title":"Hereditary disorders of connective tissue: a review","volume":"5","author":"Klett","year":"1997","journal-title":"Wound Rep Reg"},{"key":"R39-11-20210129","doi-asserted-by":"crossref","first-page":"1658","DOI":"10.1016\/S0140-6736(96)91489-0","article-title":"Changes in metabolism of collagen in genitourinary prolapse","volume":"347","author":"Jackson","year":"1996","journal-title":"Lancet"},{"key":"R40-11-20210129","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1111\/j.0001-6349.2004.00438.x","article-title":"Young women with genital prolapse have a low collagen concentration","volume":"83","author":"S\u00f6derberg","year":"2004","journal-title":"Acta Obstet Gynecol Scand"},{"key":"R41-11-20210129","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1007\/s00192-004-1191-3","article-title":"mRNA assessment for procollagen production in women with genuine stress urinary incontinence","volume":"15","author":"Bakas","year":"2004","journal-title":"Int Urogynecol J"},{"key":"R42-11-20210129","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1007\/s002400000120","article-title":"Changes in the quantity of type I in women with genuine stress incontinence","volume":"28","author":"Liapis","year":"2000","journal-title":"Urol Res"},{"key":"R43-11-20210129","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/S0301-2115(00)00478-4","article-title":"Changes of collagen type III in female patients with genuine stress incontience and pelvic floor prolapse","volume":"97","author":"Liapis","year":"2001","journal-title":"Eur J Obstet Gynecol Rep Biol"},{"key":"R44-11-20210129","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1007\/s001920200020","article-title":"Collagen metabolism and turnover in women with stress urinary incontience and pelvic prolapse","volume":"13","author":"Chen","year":"2002","journal-title":"Int Urogynecol J"},{"key":"R45-11-20210129","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1034\/j.1600-0412.2003.00019.x","article-title":"Periurethral connective tissue status of postmenopausal women with genital prolapse with and without stress incontinence","volume":"82","author":"Goepel","year":"2003","journal-title":"Acta Obstet Gynecol Scand"},{"key":"R47-11-20210129","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1111\/j.1471-0528.1997.tb12055.x","article-title":"Analysis of collagen status in premenopausal nulliparous women with genuine stress incontinence","volume":"104","author":"Keane","year":"1997","journal-title":"Br J Ob Gyn"},{"key":"R48-11-20210129","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1097\/01.AOG.0000182584.15087.dd","article-title":"Remodeling of vaginal connective tissue in patients with prolapse","volume":"106","author":"Moalli","year":"2005","journal-title":"Obstet Gynecol"},{"key":"R49-11-20210129","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1007\/s004040100194","article-title":"Histopathological evaluation of the connective tissue of the vaginal fascia and the uterine ligaments in women with and without pelvic relaxation","volume":"266","author":"K\u00f6k\u00e7\u00fc","year":"2002","journal-title":"Arch Gynecol Obstet"},{"key":"R50-11-20210129","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1002\/nau.20006","article-title":"Collagen synthesis is not altered in women with stress urinary incontinence","volume":"23","author":"Chen","year":"2005","journal-title":"Neurourol Urodyn"},{"key":"R51-11-20210129","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1007\/s00240-002-0293-y","article-title":"Differences in the quantity of elastic fibres and collagen type I and type III in endopelvic fascia between women with stress urinary incontinence and controls","volume":"31","author":"Cor","year":"2003","journal-title":"Urol Res"},{"key":"R52-11-20210129","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1016\/j.ajog.2005.07.034","article-title":"An alpha-1 chain of type I collagen Sp1-binding site polymorphism in women suffering from stress urinary incontinence","volume":"194","author":"Skorupski","year":"2006","journal-title":"Am J Obstet Gynecol"},{"key":"R53-11-20210129","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1172\/JCI10347","article-title":"A COL1A1 Sp1 binding site polymorphism predisposes to osteoporotic fracture by affecting bone density and quality","volume":"107","author":"Mann","year":"2001","journal-title":"J Clin Invest"},{"key":"R54-11-20210129","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1006\/cbir.1997.0192","article-title":"Decrease in elastin gene expression and protein synthesis in fibroblasts derived from cardinal ligaments of patients with prolapsus uteri","volume":"21","author":"Yamamoto","year":"1997","journal-title":"Cell Biol Int"},{"key":"R55-11-20210129","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1002\/nau.20347","article-title":"The role of neutrophil elastase in elastin metabolism of pelvic tissues from women with stress urinary incontinence","volume":"26","author":"Chen","year":"2007","journal-title":"Neurourol Urodyn"},{"key":"R56-11-20210129","doi-asserted-by":"crossref","first-page":"519","DOI":"10.2353\/ajpath.2006.050399","article-title":"Failure of elastic fiber homeostasis leads to pelvic floor disorders","volume":"168","author":"Liu","year":"2006","journal-title":"Am J Path"},{"key":"R57-11-20210129","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1038\/ng1297","article-title":"Elastic fiber homeostasis requires lysyl oxidase-like 1 protein","volume":"36","author":"Liu","year":"2004","journal-title":"Nat Genet"},{"key":"R58-11-20210129","doi-asserted-by":"crossref","first-page":"578","DOI":"10.2353\/ajpath.2007.060662","article-title":"Pelvic organ prolapse in fibulin-5 knockout mice","volume":"170","author":"Drewes","year":"2007","journal-title":"Am J Pathol"},{"key":"R59-11-20210129","first-page":"827","article-title":"Expression of lysyl oxidase and transforming growth factor beta2 in women with severe pelvic organ prolapse","volume":"50","author":"Kobak","year":"2005","journal-title":"J Reprod Med"},{"key":"R60-11-20210129","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1007\/s00439-006-0267-1","article-title":"Sequence variant in the laminin \u03b31 (LAMC1) gene associated with familial pelvic organ prolapse","volume":"120","author":"Nikolova","year":"2007","journal-title":"Hum Genet"}],"container-title":["Current Opinion in Obstetrics & Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.1097\/GCO.0b013e3282efdc21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T17:44:44Z","timestamp":1786038284000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00001703-200710000-00011"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,10]]},"references-count":59,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2007]]}},"URL":"https:\/\/doi.org\/10.1097\/gco.0b013e3282efdc21","relation":{},"ISSN":["1040-872X"],"issn-type":[{"value":"1040-872X","type":"print"}],"subject":[],"published":{"date-parts":[[2007,10]]}}}