{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:05:46Z","timestamp":1786118746764,"version":"build-2736575974"},"reference-count":31,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2007,9]]},"DOI":"10.1097\/gme.0b013e3180399486","type":"journal-article","created":{"date-parts":[[2007,4,4]],"date-time":"2007-04-04T04:07:27Z","timestamp":1175659647000},"page":"919-924","source":"Crossref","is-referenced-by-count":41,"title":["Effect of Pueraria mirifica on vaginal health"],"prefix":"10.1097","volume":"14","author":[{"given":"Jittima","family":"Manonai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Apichart","family":"Chittacharoen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Urusa","family":"Theppisai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hathai","family":"Theppisai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-22-20210227","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1007\/s00192-003-1042-7","article-title":"Expression of estrogen receptor- and - in anterior vaginal walls of genuine stress incontinent women.","volume":"14","author":"Fu","year":"2003","journal-title":"Int Urogynecol J Pelvic Floor Dysfunct"},{"key":"R2-22-20210227","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1080\/0144361031000120978","article-title":"Prevalence of sexual dysfunction in a cohort of middle-aged women: influence of menopause and hormone replacement therapy.","volume":"23","author":"Castelo-Branco","year":"2003","journal-title":"J Obstet Gynaecol"},{"key":"R3-22-20210227","first-page":"722","article-title":"Meta-analysis of estrogen therapy in the management of urogenital atrophy in postmenopausal women.","volume":"92","author":"Cardozo","year":"1998","journal-title":"Obstet Gynecol"},{"key":"R4-22-20210227","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1001\/jama.288.3.321","article-title":"Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women's Health Initiative randomized controlled trial.","volume":"288","year":"2002","journal-title":"JAMA"},{"key":"R5-22-20210227","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1097\/01.gme.0000172595.68648.16","article-title":"Recent reversal of trends in hormone therapy use in a European population.","volume":"13","author":"Morabia","year":"2006","journal-title":"Menopause"},{"key":"R6-22-20210227","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1097\/01.gme.0000191211.51232.9d","article-title":"Attitudes of Korean clinicians to postmenopausal hormone therapy after the Women's Health Initiative study.","volume":"13","author":"Kang","year":"2006","journal-title":"Menopause"},{"issue":"Suppl","key":"R7-22-20210227","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.amjmed.2005.09.059","article-title":"Estrogens and progestins: background and history, trends in use, and guidelines and regimens approved by the US Food and Drug Administration.","volume":"118","author":"Stefanick","year":"2005","journal-title":"Am J Med"},{"key":"R8-22-20210227","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1089\/jwh.2005.14.634","article-title":"Botanical and dietary supplements for menopausal symptoms: what works, what does not.","volume":"14","author":"Geller","year":"2005","journal-title":"J Womens Health"},{"key":"R9-22-20210227","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1080\/13697130500345257","article-title":"Effect of pure genistein on bone markers and hot flushes.","volume":"8","author":"Albertazzi","year":"2005","journal-title":"Climacteric"},{"key":"R10-22-20210227","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.maturitas.2005.09.011","article-title":"The effect of a soy-rich diet on urogenital atrophy: a randomized, cross-over trial.","volume":"54","author":"Manonai","year":"2006","journal-title":"Maturitas"},{"key":"R11-22-20210227","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.fertnstert.2004.09.003","article-title":"Lack of effect of isoflavonoids on the vagina and endometrium in postmenopausal women.","volume":"83","author":"Nikander","year":"2005","journal-title":"Fertil Steril"},{"key":"R12-22-20210227","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1021\/np990547v","article-title":"Identification of deoxymiroestrol as the actual rejuvenating principle of \"Kwao Keur\", Pueraria mirifica. The known miroestrol may be an artifact.","volume":"63","author":"Chansakaow","year":"2000","journal-title":"J Nat Prod"},{"key":"R13-22-20210227","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1677\/joe.0.0220293","article-title":"The effect of miroestrol on vaginal cornification, pituitary function and pregnancy in the rat.","volume":"22","author":"Jones","year":"1961","journal-title":"J Endocrinol"},{"key":"R15-22-20210227","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1385\/ENDO:29:1:129","article-title":"The estrogenic effect of Pueraria mirifica on gonadotropin levels in aged monkeys.","volume":"29","author":"Trisomboon","year":"2006","journal-title":"Endocrine"},{"key":"R16-22-20210227","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1385\/ENDO:26:1:033","article-title":"Ovulation block by Pueraria mirifica: a study of its endocrinological effect in female monkeys.","volume":"26","author":"Trisomboon","year":"2005","journal-title":"Endocrine"},{"key":"R17-22-20210227","first-page":"15","article-title":"The estrogenic substance (miroestrol) from the tuberous roots of P. mirifica.","volume":"17","author":"Pope","year":"1958","journal-title":"J Endocrinol"},{"key":"R18-22-20210227","first-page":"183","article-title":"Oestrogenic principle of Butea superba, preliminary report.","volume":"24","author":"Sukavattana","year":"1940","journal-title":"J Med Assoc Thai"},{"key":"R20-22-20210227","first-page":"249","article-title":"The maturation value.","volume":"11","author":"Meisels","year":"1967","journal-title":"Acta Cytol"},{"key":"R21-22-20210227","first-page":"445","article-title":"Estrogen deprivation and vaginal function in postmenopausal women.","volume":"248","author":"Semmens","year":"1982","journal-title":"J Am Med Soc"},{"key":"R23-22-20210227","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1016\/0002-9378(94)90074-4","article-title":"A comparative multicenter study of the effects of continuous low dose estradiol released from a new vaginal ring versus estriol pessaries in postmenopausal women with signs and symptoms of urogenital atrophy.","volume":"171","author":"Henriksson","year":"1994","journal-title":"Am J Obstet Gynecol"},{"key":"R24-22-20210227","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1111\/j.1447-0756.2001.tb01266.x","article-title":"The effect of estradiol vaginal tablet and conjugated estrogen cream on urogenital symptoms in postmenopausal women: a comparative study.","volume":"27","author":"Manonai","year":"2001","journal-title":"J Obstet Gynaecol Res"},{"key":"R25-22-20210227","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.ejogrb.2004.01.041","article-title":"Effect of estradiol valerate and levonorgestrel on vaginal health.","volume":"115","author":"Manonai","year":"2004","journal-title":"Eur J Obstet Reprod Biol"},{"key":"R26-22-20210227","first-page":"185","article-title":"Phytoestrogens in health and disease.","volume":"54","author":"Davis","year":"1999","journal-title":"Recent Prog Horm Res"},{"key":"R27-22-20210227","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1055\/s-2000-8603","article-title":"Isoflavonoids from Pueraria mirifica and their estrogenic activity.","volume":"66","author":"ChansakaowS, Ishikawa","year":"2000","journal-title":"Planta Med"},{"issue":"Suppl","key":"R28-22-20210227","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.maturitas.2005.06.014","article-title":"Management of post-menopausal vaginal atrophy and atrophic vaginitis.","volume":"52","author":"Castelo-Branco","year":"2005","journal-title":"Maturitas"},{"key":"R29-22-20210227","first-page":"1685","article-title":"Dietary intervention study to assess estrogenicity of dietary soy among postmenopausal women.","volume":"80","author":"Baird","year":"1995","journal-title":"J Clin Endocrinol Metab"},{"key":"R30-22-20210227","doi-asserted-by":"crossref","first-page":"124","DOI":"10.3109\/13697139809085527","article-title":"Effects of dietary phytoestrogens in postmenopausal women.","volume":"1","author":"Dalais","year":"1998","journal-title":"Climacteric"},{"key":"R31-22-20210227","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1254\/jphs.FPJ04029X","article-title":"Different effects of Pueraria mirifica, a herb containing phytoestrogens, on LH and FSH secretion in gonadectomized female and male rats.","volume":"96","author":"Malaivijitnond","year":"2004","journal-title":"J Pharmacol Sci"},{"key":"R33-22-20210227","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1095\/biolreprod.104.029512","article-title":"Estrogenicity of the isoflavone metabolite equol on reproductive and non-reproductive organs in mice.","volume":"71","author":"Selvaraj","year":"2004","journal-title":"Biol Reprod"},{"key":"R34-22-20210227","first-page":"3479","article-title":"Modest hormonal effects of soy isoflavones in postmenopausal women.","volume":"84","author":"Duncan","year":"1999","journal-title":"J Clin Endocrinol Metab"},{"key":"R35-22-20210227","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/S1071-5576(02)00152-1","article-title":"A pilot study of the effects of phytoestrogen supplementation on postmenopausal endometrium.","volume":"9","author":"Balk","year":"2002","journal-title":"J Soc Gynecol Investig"}],"container-title":["Menopause"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00042192-200714050-00022","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T16:36:23Z","timestamp":1786034183000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00042192-200714050-00022"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,9]]},"references-count":31,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2007]]}},"URL":"https:\/\/doi.org\/10.1097\/gme.0b013e3180399486","relation":{},"ISSN":["1072-3714"],"issn-type":[{"value":"1072-3714","type":"print"}],"subject":[],"published":{"date-parts":[[2007,9]]}}}