{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T04:48:38Z","timestamp":1791089318056,"version":"4.1.0"},"reference-count":64,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,7]]},"DOI":"10.1097\/gme.0b013e31827cabca","type":"journal-article","created":{"date-parts":[[2013,3,22]],"date-time":"2013-03-22T21:22:33Z","timestamp":1363987353000},"page":"747-753","source":"Crossref","is-referenced-by-count":46,"title":["Concomitant increase in muscle strength and bone mineral density with decreasing IL-6 levels after combination therapy with alendronate and calcitriol in postmenopausal women"],"prefix":"10.1097","volume":"20","author":[{"given":"Joo Hyun","family":"Park","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ki Hyun","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"SiHyun","family":"Cho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young Sik","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seok Kyo","family":"Seo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Byung Seok","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hoon Suk","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-9-20210211","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1152\/jappl.2000.88.4.1321","article-title":"Aging of skeletal muscle: a 12-yr longitudinal study.","volume":"88","author":"Frontera","year":"2000","journal-title":"J Appl Physiol"},{"key":"R2-9-20210211","doi-asserted-by":"crossref","first-page":"2368","DOI":"10.1152\/japplphysiol.00124.2002","article-title":"One- and two-year change in body composition as measured by DXA in a population-based cohort of older men and women.","volume":"94","author":"Visser","year":"2003","journal-title":"J Appl Physiol"},{"key":"R3-9-20210211","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1007\/s00198-008-0560-z","article-title":"European guidance for the diagnosis and management of osteoporosis in postmenopausal women.","volume":"19","author":"Kanis","year":"2008","journal-title":"Osteoporos Int"},{"issue":"suppl 1","key":"R4-9-20210211","doi-asserted-by":"crossref","first-page":"274S","DOI":"10.1093\/ajcn\/54.1.274S","article-title":"Calcium supplementation and bone loss: a review of controlled clinical trials.","volume":"54","author":"Dawson-Hughes","year":"1991","journal-title":"Am J Clin Nutr"},{"key":"R5-9-20210211","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1002\/jbmr.5650070511","article-title":"Bone mineral density in elderly men and women: results from the Framingham Osteoporosis Study.","volume":"7","author":"Hannan","year":"1992","journal-title":"J Bone Miner Res"},{"key":"R6-9-20210211","doi-asserted-by":"crossref","first-page":"1778","DOI":"10.1002\/jbmr.5650101122","article-title":"Hip and calcaneal bone loss increase with advancing age: longitudinal results from the study of osteoporotic fractures.","volume":"10","author":"Ensrud","year":"1995","journal-title":"J Bone Miner Res"},{"key":"R7-9-20210211","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1111\/j.1440-1681.2007.04752.x","article-title":"Age-related changes in the structure and function of skeletal muscles.","volume":"34","author":"Faulkner","year":"2007","journal-title":"Clin Exp Pharmacol Physiol"},{"key":"R8-9-20210211","doi-asserted-by":"crossref","first-page":"809","DOI":"10.2165\/00007256-200434120-00002","article-title":"Effects of aging on muscle fibre type and size.","volume":"34","author":"Deschenes","year":"2004","journal-title":"Sports Med"},{"key":"R9-9-20210211","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1002\/mus.1215","article-title":"Aging of the human neuromuscular system.","volume":"25","author":"Vandervoort","year":"2002","journal-title":"Muscle Nerve"},{"key":"R10-9-20210211","doi-asserted-by":"crossref","first-page":"M716","DOI":"10.1093\/gerona\/55.12.M716","article-title":"Sarcopenia: current concepts.","volume":"55","author":"Roubenoff","year":"2000","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"R11-9-20210211","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1067\/mlc.2001.113504","article-title":"Sarcopenia.","volume":"137","author":"Morley","year":"2001","journal-title":"J Lab Clin Med"},{"issue":"suppl 5","key":"R12-9-20210211","first-page":"998S","article-title":"Functional and metabolic consequences of sarcopenia.","volume":"127","author":"Evans","year":"1997","journal-title":"J Nutr"},{"key":"R13-9-20210211","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1034\/j.1600-0579.2003.00207.x","article-title":"Handgrip strength and cause-specific and total mortality in older disabled women: exploring the mechanism.","volume":"51","author":"Rantanen","year":"2003","journal-title":"J Am Geriatr Soc"},{"key":"R14-9-20210211","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1093\/gerona\/glq056","article-title":"Inflammatory markers and physical performance among nonagenarians.","volume":"65","author":"Tiainen","year":"2010","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"R15-9-20210211","doi-asserted-by":"crossref","first-page":"1947","DOI":"10.1046\/j.1532-5415.2002.50605.x","article-title":"Change in muscle strength explains accelerated decline of physical function in older women with high interleukin-6 serum levels.","volume":"50","author":"Ferrucci","year":"2002","journal-title":"J Am Geriatr Soc"},{"key":"R16-9-20210211","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1007\/s00198-005-1900-x","article-title":"Sarcopenia in premenopausal and postmenopausal women with osteopenia, osteoporosis and normal bone mineral density.","volume":"17","author":"Walsh","year":"2006","journal-title":"Osteoporos Int"},{"key":"R17-9-20210211","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1016\/j.bone.2010.12.025","article-title":"Severe osteopenia and osteoporosis, sarcopenia, and frailty status in community-dwelling older women: results from the Womens Health and Aging Study (WHAS) II.","volume":"48","author":"Frisoli","year":"2011","journal-title":"Bone"},{"key":"R18-9-20210211","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1093\/aje\/kwn407","article-title":"Lifestyle impact on lifetime bone loss in women and men: the Tromso Study.","volume":"169","author":"Wilsgaard","year":"2009","journal-title":"Am J Epidemiol"},{"key":"R19-9-20210211","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1359\/JBMR.041230","article-title":"Low skeletal muscle mass is associated with poor structural parameters of bone and impaired balance in elderly menthe MINOS study.","volume":"20","author":"Szulc","year":"2005","journal-title":"J Bone Miner Res"},{"key":"R20-9-20210211","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1007\/s00198-006-0071-8","article-title":"Higher 1,25-dihydroxyvitamin D3 concentrations associated with lower fall rates in older community-dwelling women.","volume":"17","author":"Faulkner","year":"2006","journal-title":"Osteoporos Int"},{"key":"R21-9-20210211","doi-asserted-by":"crossref","first-page":"M492","DOI":"10.1093\/gerona\/55.9.M492","article-title":"Determinants of bone density in healthy older men with low testosterone levels.","volume":"55","author":"Kenny","year":"2000","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"R22-9-20210211","doi-asserted-by":"crossref","first-page":"657","DOI":"10.7326\/0003-4819-118-9-199305010-00001","article-title":"Factors associated with appendicular bone mass in older women. The Study of Osteoporotic Fractures Research Group.","volume":"118","author":"Bauer","year":"1993","journal-title":"Ann Intern Med"},{"key":"R23-9-20210211","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1007\/s00223-003-0090-9","article-title":"Insulin-like growth factor I is a determinant of hip bone mineral density in men less than 60 years of age: MINOS study.","volume":"74","author":"Szulc","year":"2004","journal-title":"Calcif Tissue Int"},{"key":"R24-9-20210211","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1111\/j.1532-5415.2007.01567.x","article-title":"The mediating role of C-reactive protein and handgrip strength between obesity and walking limitation.","volume":"56","author":"Stenholm","year":"2008","journal-title":"J Am Geriatr Soc"},{"key":"R25-9-20210211","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1152\/japplphysiol.00133.2007","article-title":"Oxidative protein damage is associated with poor grip strength among older women living in the community.","volume":"103","author":"Howard","year":"2007","journal-title":"J Appl Physiol"},{"key":"R26-9-20210211","doi-asserted-by":"crossref","first-page":"2682","DOI":"10.1002\/jbmr.489","article-title":"Cytoplasmic superoxide causes bone fragility owing to low-turnover osteoporosis and impaired collagen cross-linking.","volume":"26","author":"Nojiri","year":"2011","journal-title":"J Bone Miner Res"},{"key":"R27-9-20210211","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.archger.2009.12.006","article-title":"Influence of body composition on bone mass in postmenopausal osteoporotic women.","volume":"51","author":"Genaro","year":"2010","journal-title":"Arch Gerontol Geriatr"},{"key":"R28-9-20210211","doi-asserted-by":"crossref","first-page":"1772","DOI":"10.1001\/jama.297.16.1772-b","article-title":"Effect of 10 days of bed rest on skeletal muscle in healthy older adults.","volume":"297","author":"Kortebein","year":"2007","journal-title":"JAMA"},{"key":"R29-9-20210211","doi-asserted-by":"crossref","first-page":"1780","DOI":"10.1152\/jappl.1992.72.5.1780","article-title":"Skeletal muscle adaptations to endurance training in 60- to 70-yr-old men and women.","volume":"72","author":"Coggan","year":"1992","journal-title":"J Appl Physiol"},{"key":"R30-9-20210211","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1002\/jbmr.181","article-title":"The effects of whole-body vibration training and vitamin D supplementation on muscle strength, muscle mass, and bone density in institutionalized elderly women: a 6-month randomized, controlled trial.","volume":"26","author":"Verschueren","year":"2011","journal-title":"J Bone Miner Res"},{"key":"R32-9-20210211","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1152\/jappl.1995.78.1.334","article-title":"Effects of strength and endurance training on thigh and leg muscle mass and composition in elderly women.","volume":"78","author":"Sipila","year":"1995","journal-title":"J Appl Physiol"},{"key":"R33-9-20210211","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1006\/bbrc.2002.6510","article-title":"Bisphosphonates pamidronate and zoledronic acid stimulate osteoprotegerin production by primary human osteoblasts.","volume":"291","author":"Viereck","year":"2002","journal-title":"Biochem Biophys Res Commun"},{"key":"R34-9-20210211","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1080\/030097498441155","article-title":"Bisphosphonates inhibit IL-6 production by human osteoblast-like cells.","volume":"27","author":"Giuliani","year":"1998","journal-title":"Scand J Rheumatol"},{"key":"R35-9-20210211","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1034\/j.1600-0609.2003.02823.x","article-title":"Pamidronate is superior to ibandronate in decreasing bone resorption, interleukin-6 and 2-microglobulin in multiple myeloma.","volume":"70","author":"Terpos","year":"2003","journal-title":"Eur J Haematol"},{"key":"R36-9-20210211","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1007\/s002239900704","article-title":"The advantage of alfacalcidol over vitamin D in the treatment of osteoporosis.","volume":"65","author":"Shiraishi","year":"1999","journal-title":"Calcif Tissue Int"},{"key":"R37-9-20210211","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1016\/S0140-6736(05)63013-9","article-title":"Oral vitamin D3 and calcium for secondary prevention of low-trauma fractures in elderly people (Randomised Evaluation of Calcium OR vitamin D, RECORD): a randomised placebo-controlled trial.","volume":"365","author":"Grant","year":"2005","journal-title":"Lancet"},{"key":"R38-9-20210211","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1007\/s00296-006-0288-z","article-title":"Superiority of a combined treatment of alendronate and alfacalcidol compared to the combination of alendronate and plain vitamin D or alfacalcidol alone in established postmenopausal or male osteoporosis (AAC-Trial).","volume":"27","author":"Ringe","year":"2007","journal-title":"Rheumatol Int"},{"key":"R39-9-20210211","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1007\/s00774-004-0508-0","article-title":"Alendronate reduced vertebral fracture risk in postmenopausal Japanese women with osteoporosis: a 3-year follow-up study.","volume":"22","author":"Kushida","year":"2004","journal-title":"J Bone Miner Metab"},{"key":"R40-9-20210211","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1007\/s00774-004-0590-3","article-title":"Early changes in urinary cross-linked N-terminal telopeptides of type I collagen level correlate with 1-year response of lumbar bone mineral density to alendronate in postmenopausal Japanese women with osteoporosis.","volume":"23","author":"Iwamoto","year":"2005","journal-title":"J Bone Miner Metab"},{"key":"R41-9-20210211","doi-asserted-by":"crossref","first-page":"1801","DOI":"10.1007\/s00198-006-0200-4","article-title":"Effects of a combined alendronate and calcitriol agent (Maxmarvil) on bone metabolism in Korean postmenopausal women: a multicenter, double-blind, randomized, placebo-controlled study.","volume":"17","author":"Rhee","year":"2006","journal-title":"Osteoporos Int"},{"key":"R42-9-20210211","doi-asserted-by":"crossref","first-page":"9090","DOI":"10.1073\/pnas.1531903100","article-title":"Chronic stress and age-related increases in the proinflammatory cytokine IL-6.","volume":"100","author":"Kiecolt-Glaser","year":"2003","journal-title":"Proc Natl Acad Sci U S A"},{"key":"R43-9-20210211","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1007\/s11357-011-9244-2","article-title":"Effects of aging and menopause on serum interleukin-6 levels and peripheral blood mononuclear cell cytokine production in healthy nonobese women.","volume":"34","author":"Kim","year":"2012","journal-title":"Age"},{"key":"R44-9-20210211","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1007\/s00421-011-2072-3","article-title":"Relationship of low plasma klotho with poor grip strength in older community-dwelling adults: the InCHIANTI study.","volume":"112","author":"Semba","year":"2012","journal-title":"Eur J Appl Physiol"},{"key":"R45-9-20210211","doi-asserted-by":"crossref","first-page":"1550","DOI":"10.1210\/jcem.87.4.8397","article-title":"Effect of estrogen versus testosterone on circulating osteoprotegerin and other cytokine levels in normal elderly men.","volume":"87","author":"Khosla","year":"2002","journal-title":"J Clin Endocrinol Metab"},{"key":"R46-9-20210211","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1016\/S0047-6374(02)00071-4","article-title":"Osteoclastogenic potential of bone marrow cells increases with age in elderly women with fracture.","volume":"123","author":"Koshihara","year":"2002","journal-title":"Mech Ageing Dev"},{"key":"R47-9-20210211","first-page":"2032","article-title":"Serum interleukin 6 is a major predictor of bone loss in women specific to the first decade past menopause.","volume":"86","author":"Scheidt-Nave","year":"2001","journal-title":"J Clin Endocrinol Metab"},{"key":"R48-9-20210211","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1210\/jc.2002-020092","article-title":"Two promoter polymorphisms regulating interleukin-6 gene expression are associated with circulating levels of C-reactive protein and markers of bone resorption in postmenopausal women.","volume":"88","author":"Ferrari","year":"2003","journal-title":"J Clin Endocrinol Metab"},{"key":"R49-9-20210211","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1002\/jbmr.1559","article-title":"Inflammatory markers and the risk of hip fracture: the Womens Health Initiative.","volume":"27","author":"Barbour","year":"2012","journal-title":"J Bone Miner Res"},{"key":"R50-9-20210211","doi-asserted-by":"crossref","first-page":"1952","DOI":"10.1210\/jc.2007-2325","article-title":"Circulating levels of inflammatory markers predict change in bone mineral density and resorption in older adults: a longitudinal study.","volume":"93","author":"Ding","year":"2008","journal-title":"J Clin Endocrinol Metab"},{"key":"R51-9-20210211","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.archger.2008.02.012","article-title":"Correlation between manual muscle strength and interleukin-6 (IL-6) plasma levels in elderly community-dwelling women.","volume":"48","author":"Pereira","year":"2009","journal-title":"Arch Gerontol Geriatr"},{"key":"R52-9-20210211","doi-asserted-by":"crossref","first-page":"536735","DOI":"10.4061\/2011\/536735","article-title":"Similarities in acquired factors related to postmenopausal osteoporosis and sarcopenia.","volume":"2011","author":"Sirola","year":"2011","journal-title":"J Osteoporos"},{"key":"R53-9-20210211","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1210\/edrv.22.4.0437","article-title":"Vitamin D deficiency and secondary hyperparathyroidism in the elderly: consequences for bone loss and fractures and therapeutic implications.","volume":"22","author":"Lips","year":"2001","journal-title":"Endocr Rev"},{"key":"R54-9-20210211","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.1093\/ajcn\/71.6.1577","article-title":"Vitamin D status: effects on parathyroid hormone and 1,25-dihydroxyvitamin D in postmenopausal women.","volume":"71","author":"Need","year":"2000","journal-title":"Am J Clin Nutr"},{"key":"R55-9-20210211","doi-asserted-by":"crossref","first-page":"1745","DOI":"10.1007\/s00198-010-1383-2","article-title":"Racial differences in the relationship between vitamin D, bone mineral density, and parathyroid hormone in the National Health and Nutrition Examination Survey.","volume":"22","author":"Gutierrez","year":"2011","journal-title":"Osteoporos Int"},{"key":"R56-9-20210211","doi-asserted-by":"crossref","first-page":"3215","DOI":"10.1210\/jc.2004-2364","article-title":"Prevalence of vitamin D inadequacy among postmenopausal North American women receiving osteoporosis therapy.","volume":"90","author":"Holick","year":"2005","journal-title":"J Clin Endocrinol Metab"},{"key":"R57-9-20210211","doi-asserted-by":"crossref","first-page":"5766","DOI":"10.1210\/jc.2003-030604","article-title":"Low vitamin D and high parathyroid hormone levels as determinants of loss of muscle strength and muscle mass (sarcopenia): the Longitudinal Aging Study Amsterdam.","volume":"88","author":"Visser","year":"2003","journal-title":"J Clin Endocrinol Metab"},{"key":"R58-9-20210211","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1210\/jc.2008-1832","article-title":"Relationships of serum 25-hydroxyvitamin D to bone mineral density and serum parathyroid hormone and markers of bone turnover in older persons.","volume":"94","author":"Kuchuk","year":"2009","journal-title":"J Clin Endocrinol Metab"},{"key":"R59-9-20210211","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1016\/j.bone.2010.06.013","article-title":"Regulation of PTH secretion by 25-hydroxyvitamin D and ionized calcium depends on vitamin D status: a study in a large cohort of healthy subjects.","volume":"47","author":"Carnevale","year":"2010","journal-title":"Bone"},{"key":"R60-9-20210211","first-page":"455","article-title":"Muscle strength, functional mobility and vitamin D in older women.","volume":"12","author":"Verhaar","year":"2000","journal-title":"Aging"},{"key":"R61-9-20210211","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1007\/s00198-008-0662-7","article-title":"Effects of a long-term vitamin D and calcium supplementation on falls and parameters of muscle function in community-dwelling older individuals.","volume":"20","author":"Pfeifer","year":"2009","journal-title":"Osteoporos Int"},{"key":"R62-9-20210211","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1159\/000087203","article-title":"Low-dose vitamin D prevents muscular atrophy and reduces falls and hip fractures in women after stroke: a randomized controlled trial.","volume":"20","author":"Sato","year":"2005","journal-title":"Cerebrovasc Dis"},{"key":"R63-9-20210211","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1016\/1043-4666(92)90012-G","article-title":"1,25-Dihydroxyvitamin D3 inhibits cytokine production by human blood monocytes at the post-transcriptional level.","volume":"4","author":"Muller","year":"1992","journal-title":"Cytokine"},{"key":"R64-9-20210211","doi-asserted-by":"crossref","first-page":"2127","DOI":"10.4049\/jimmunol.1102412","article-title":"Vitamin D inhibits monocytemacrophage proinflammatory cytokine production by targeting MAPK phosphatase-1.","volume":"188","author":"Zhang","year":"2012","journal-title":"J Immunol"},{"key":"R65-9-20210211","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1007\/s00198-008-0799-4","article-title":"Vitamin D insufficiency does not affect response of bone mineral density to alendronate.","volume":"20","author":"Antoniucci","year":"2009","journal-title":"Osteoporos Int"}],"container-title":["Menopause"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/GME.0b013e31827cabca","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,14]],"date-time":"2021-05-14T00:41:06Z","timestamp":1620952866000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00042192-201307000-00009"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7]]},"references-count":64,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2013]]}},"URL":"https:\/\/doi.org\/10.1097\/gme.0b013e31827cabca","relation":{},"ISSN":["1072-3714"],"issn-type":[{"value":"1072-3714","type":"print"}],"subject":[],"published":{"date-parts":[[2013,7]]}}}