{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T22:32:35Z","timestamp":1793226755229,"version":"4.5.0"},"reference-count":25,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:sec>\n            <jats:title>Purpose of review<\/jats:title>\n            <jats:p>To bring together and annotate publications about personalised external aortic root support reported in the 18\u200amonths preceding submission.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Recent findings<\/jats:title>\n            <jats:p>The total number of personalised external aortic root support (PEARS) operations is now approaching 700 in 30 centres in Australia, Belgium, Brazil, Czech Republic, Great Britain, Greece, Ireland, Malaysia, Netherlands, New Zealand, Poland and Slovakia. There are continued reports of stability of aortic dimensions and aortic valve function with the only exceptions known being where the surgeon has deviated from the instructions for use of the device. The median root diameter of Marfan patients having PEARS was 47\u200amm suggesting that the existing criterion of 50\u200amm is due for reconsideration. The peri-operative mortality currently estimated to be less than 0.3%. The first recipient remains alive and well after 18\u200ayears. The use of PEARS as an adjunct to the Ross operation to support the pulmonary autograft is being explored in several centres.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Summary<\/jats:title>\n            <jats:p>The operation requires proctoring and adherence to a strict operative protocol and with those precautions excellent results are attained. The evidence and opinions provided in the cited publications indicate that PEARS is a proven and successful prophylactic operation for aortic root aneurysm.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/hco.0000000000000990","type":"journal-article","created":{"date-parts":[[2022,9,12]],"date-time":"2022-09-12T11:02:32Z","timestamp":1662980552000},"page":"454-458","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":11,"title":["Personalized external aortic root support in aneurysm disease"],"prefix":"10.1097","volume":"37","author":[{"given":"Tom","family":"Treasure","sequence":"first","affiliation":[{"name":"Professor of Cardiothoracic Surgery, University College London, London WC1E 6BT UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Conal","family":"Austin","sequence":"additional","affiliation":[{"name":"Consultant Cardiac Surgeon, St Thomas\u2019 Hospital, London SE1 7EH, 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