{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T00:58:36Z","timestamp":1794013116899,"version":"4.8.0"},"reference-count":46,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2009,7]]},"DOI":"10.1097\/hco.0b013e32832c1284","type":"journal-article","created":{"date-parts":[[2009,6,8]],"date-time":"2009-06-08T07:18:51Z","timestamp":1244445531000},"page":"345-350","source":"Crossref","is-referenced-by-count":123,"title":["Triglycerides as vascular risk factors: new epidemiologic insights"],"prefix":"10.1097","volume":"24","author":[{"given":"William B","family":"Kannel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramachandran S","family":"Vasan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-14-20210204","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1126\/science.106.2748.190","article-title":"Atherosclerosis and alimentary hyperlipemia","volume":"106","author":"Moreton","year":"1947","journal-title":"Science"},{"key":"R2-14-20210204","doi-asserted-by":"crossref","first-page":"2233","DOI":"10.1016\/j.jacc.2004.04.001","article-title":"Triglyceride-rich lipoprotein remnant levels and metabolism: time to adopt these orphan risk factors?","volume":"43","author":"Brinton","year":"2004","journal-title":"J Am Coll Cardiol"},{"key":"R3-14-20210204","doi-asserted-by":"crossref","first-page":"3247","DOI":"10.1172\/JCI35206","article-title":"Molecular processes that handle \u2013 and mishandle \u2013 dietary lipids","volume":"118","author":"Williams","year":"2008","journal-title":"J Clin Invest"},{"key":"R4-14-20210204","doi-asserted-by":"crossref","first-page":"1336","DOI":"10.1161\/01.ATV.12.11.1336","article-title":"Relation of triglyceride metabolism and coronary artery disease. Studies in the postprandial state","volume":"12","author":"Patsch","year":"1992","journal-title":"Arterioscler Thromb"},{"key":"R5-14-20210204","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/j.atherosclerosis.2005.01.012","article-title":"Remnant lipoproteinemia is a risk factor for endothelial vasomotor dysfunction and coronary artery disease in metabolic syndrome","volume":"181","author":"Nakamura","year":"2005","journal-title":"Atherosclerosis"},{"key":"R6-14-20210204","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1161\/01.ATV.15.4.534","article-title":"Selective retention of VLDL, IDL, and LDL in the arterial intima of genetically hyperlipidemic rabbits in vivo: molecular size as a determinant of fractional loss from the intima\u2013inner media","volume":"15","author":"Nordestgaard","year":"1995","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"R7-14-20210204","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1161\/01.ATV.11.3.569","article-title":"Quantitative studies of transfer in vivo of low density, Sf 12-60, and Sf 60-400 lipoproteins between plasma and arterial intima in humans","volume":"11","author":"Shaikh","year":"1991","journal-title":"Arterioscler Thromb"},{"key":"R8-14-20210204","doi-asserted-by":"crossref","first-page":"1832","DOI":"10.1161\/CIRCULATIONAHA.106.676890","article-title":"Subendothelial lipoprotein retention as the initiating process in atherosclerosis: update and therapeutic implications","volume":"116","author":"Tabas","year":"2007","journal-title":"Circulation"},{"key":"R9-14-20210204","doi-asserted-by":"crossref","first-page":"1767","DOI":"10.1161\/01.ATV.14.11.1767","article-title":"Triglyceride-rich lipoproteins isolated by selected-affinity antiapolipoprotein B immunosorption from human atherosclerotic plaque","volume":"14","author":"Rapp","year":"1994","journal-title":"Arterioscler Thromb"},{"key":"R10-14-20210204","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1161\/01.CIR.82.2.495","article-title":"Atherogenic lipoprotein phenotype. A proposed genetic marker for coronary heart disease risk","volume":"82","author":"Austin","year":"1990","journal-title":"Circulation"},{"key":"R11-14-20210204","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1194\/jlr.R200004-JLR200","article-title":"Metabolic origins and clinical significance of LDL heterogeneity","volume":"43","author":"Berneis","year":"2002","journal-title":"J Lipid Res"},{"key":"R12-14-20210204","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/0021-9150(94)05454-Q","article-title":"Fasting and postprandial determinants for the occurrence of small dense LDL species in noninsulin-dependent diabetic patients with and without hypertriglyceridaemia: the involvement of insulin, insulin precursor species and insulin resistance","volume":"113","author":"Tan","year":"1995","journal-title":"Atherosclerosis"},{"key":"R13-14-20210204","doi-asserted-by":"crossref","first-page":"1556","DOI":"10.1161\/CIRCULATIONAHA.105.565135","article-title":"Low-density lipoprotein and high-density lipoprotein particle subclasses predict coronary events and are favorably changed by gemfibrozil therapy in the veterans affairs high-density lipoprotein intervention trial","volume":"113","author":"Otvos","year":"2006","journal-title":"Circulation"},{"key":"R14-14-20210204","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/S0009-9120(03)00078-X","article-title":"Mechanisms of HDL lowering in insulin resistant, hypertriglyceridemic states: the combined effect of HDL triglyceride enrichment and elevated hepatic lipase activity","volume":"36","author":"Rashid","year":"2003","journal-title":"Clin Biochem"},{"key":"R15-14-20210204","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1210\/jc.2005-1895","article-title":"High-density lipoprotein (hdl) transport in the metabolic syndrome: application of a new model for HDL particle kinetics","volume":"91","author":"Ji","year":"2006","journal-title":"J Clin Endocrinol Metab"},{"key":"R16-14-20210204","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1210\/jc.2006-2676","article-title":"Plasma apolipoprotein C-III transport in centrally obese men: associations with very low-density lipoprotein apolipoprotein B and high-density lipoprotein apolipoprotein A-I metabolism","volume":"93","author":"Chan","year":"2008","journal-title":"J Clin Endocrinol Metab"},{"key":"R17-14-20210204","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1007\/s00125-005-0125-z","article-title":"Overproduction of large VLDL particles is driven by increased liver fat content in man","volume":"49","author":"Adiels","year":"2006","journal-title":"Diabetologia"},{"key":"R18-14-20210204","doi-asserted-by":"crossref","first-page":"3052","DOI":"10.1210\/jc.2007-0187","article-title":"Postprandial lipemia associates with liver fat content","volume":"92","author":"Matikainen","year":"2007","journal-title":"J Clin Endocrinol Metab"},{"key":"R19-14-20210204","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1172\/JCI115028","article-title":"Increased apo A-I and apo A-II fractional catabolic rate in patients with low high density lipoprotein-cholesterol levels with or without hypertriglyceridemia","volume":"87","author":"Brinton","year":"1991","journal-title":"J Clin Invest"},{"key":"R20-14-20210204","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1161\/01.RES.0000058881.44913.7B","article-title":"Cardioprotection with high-density lipoproteins: fact or fiction?","volume":"92","author":"Das","year":"2003","journal-title":"Circ Res"},{"key":"R21-14-20210204","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1038\/ng.291","article-title":"Common variants at 30 loci contribute to polygenic dyslipidemia","volume":"41","author":"Kathiresan","year":"2009","journal-title":"Nat Genet"},{"key":"R22-14-20210204","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1038\/ng.75","article-title":"Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans","volume":"40","author":"Kathiresan","year":"2008","journal-title":"Nat Genet"},{"key":"R23-14-20210204","doi-asserted-by":"crossref","first-page":"1773","DOI":"10.1001\/jama.294.14.1773","article-title":"Trends in serum lipids and lipoproteins of adults, 1960\u20132002","volume":"294","author":"Carroll","year":"2005","journal-title":"JAMA"},{"key":"R24-14-20210204","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.ahj.2008.03.005","article-title":"Prevalence and extent of dyslipidemia and recommended lipid levels in US adults with and without cardiovascular comorbidities: the National Health and Nutrition Examination Survey 2003\u20132004","volume":"156","author":"Ghandehari","year":"2008","journal-title":"Am Heart J"},{"key":"R25-14-20210204","first-page":"S470","article-title":"US adults: findings from the National Health and Nutrition Examination Survey II, III, and 1999-2006.","volume":"118","year":"2009","journal-title":"Circulation"},{"key":"R26-14-20210204","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1161\/CIRCULATIONAHA.106.637793","article-title":"Triglycerides and the risk of coronary heart disease: 10 158 incident cases among 262 525 participants in 29 western prospective studies","volume":"115","author":"Sarwar","year":"2007","journal-title":"Circulation"},{"key":"R27-14-20210204","doi-asserted-by":"crossref","first-page":"2678","DOI":"10.1161\/01.CIR.0000145615.33955.83","article-title":"Collaboration: serum triglycerides as a risk factor for cardiovascular diseases in the Asia-Pacific Region.","volume":"110","year":"2004","journal-title":"Circulation"},{"key":"R28-14-20210204","doi-asserted-by":"crossref","first-page":"377","DOI":"10.7326\/0003-4819-147-6-200709180-00007","article-title":"Changes in triglyceride levels and risk for coronary heart disease in young men","volume":"147","author":"Tirosh","year":"2007","journal-title":"Ann Intern Med"},{"key":"R29-14-20210204","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1001\/archinte.1959.00270010010002","article-title":"Serum triglycerides in coronary artery disease","volume":"103","author":"Albrink","year":"1959","journal-title":"Arch Intern Med"},{"key":"R30-14-20210204","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1161\/01.ATV.1.4.273","article-title":"Multivariate analyses of serum apolipoproteins and risk factors in relation to acute myocardial infarction","volume":"1","author":"Fager","year":"1981","journal-title":"Arteriosclerosis"},{"key":"R31-14-20210204","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1172\/JCI107331","article-title":"Hyperlipidemia in coronary heart disease. I: lipid levels in 500 survivors of myocardial infarction","volume":"52","author":"Goldstein","year":"1973","journal-title":"J Clin Invest"},{"key":"R32-14-20210204","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1136\/hrt.68.7.60","article-title":"Plasma triglyceride and high density lipoprotein cholesterol as predictors of ischaemic heart disease in British men: the Caerphilly and Speedwell Collaborative Heart Disease Studies","volume":"68","author":"Bainton","year":"1992","journal-title":"Br Heart J"},{"key":"R33-14-20210204","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1161\/01.ATV.11.1.2","article-title":"Plasma triglyceride and coronary heart disease","volume":"11","author":"Austin","year":"1991","journal-title":"Arterioscler Thromb"},{"key":"R34-14-20210204","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1161\/01.CIR.60.3.473","article-title":"Atherogenesis: a postprandial phenomenon","volume":"60","author":"Zilversmit","year":"1979","journal-title":"Circulation"},{"key":"R35-14-20210204","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1055\/s-2002-35403","article-title":"The complex role of triglycerides in cardiovascular disease","volume":"2","author":"Abdel-Maksoud","year":"2002","journal-title":"Semin Vasc Med"},{"key":"R36-14-20210204","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1097\/00043798-199604000-00014","article-title":"Plasma triglyceride level is a risk factor for cardiovascular disease independent of high-density lipoprotein cholesterol level: a meta-analysis of population-based prospective studies","volume":"3","author":"Hokanson","year":"1996","journal-title":"J Cardiovasc Risk"},{"key":"R37-14-20210204","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1001\/jama.298.3.309","article-title":"Fasting compared with nonfasting triglycerides and risk of cardiovascular events in women","volume":"298","author":"Bansal","year":"2007","journal-title":"JAMA"},{"key":"R38-14-20210204","doi-asserted-by":"crossref","first-page":"2142","DOI":"10.1001\/jama.2008.621","article-title":"Nonfasting triglycerides and risk of ischemic stroke in the general population","volume":"300","author":"Freiberg","year":"2008","journal-title":"JAMA"},{"key":"R39-14-20210204","doi-asserted-by":"crossref","first-page":"2047","DOI":"10.1161\/CIRCULATIONAHA.108.804146","article-title":"Fasting and nonfasting lipid levels: influence of normal food intake on lipids, lipoproteins, apolipoproteins, and cardiovascular risk prediction","volume":"118","author":"Langsted","year":"2008","journal-title":"Circulation"},{"key":"R40-14-20210204","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1161\/CIRCULATIONAHA.108.777334","article-title":"Fasting compared with nonfasting lipids and apolipoproteins for predicting incident cardiovascular events","volume":"118","author":"Mora","year":"2008","journal-title":"Circulation"},{"key":"R41-14-20210204","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1001\/jama.298.3.299","article-title":"Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women","volume":"298","author":"Nordestgaard","year":"2007","journal-title":"JAMA"},{"key":"R42-14-20210204","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/j.amjcard.2007.09.109","article-title":"Usefulness of the triglyceride-high-density lipoprotein versus the cholesterol-high-density lipoprotein ratio for predicting insulin resistance and cardiometabolic risk (from the Framingham Offspring Cohort)","volume":"101","author":"Kannel","year":"2008","journal-title":"Am J Cardiol"},{"key":"R43-14-20210204","doi-asserted-by":"crossref","first-page":"2486","DOI":"10.1001\/jama.285.19.2486","article-title":"Detection, Evaluation, And Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III).","volume":"285","year":"2001","journal-title":"JAMA"},{"key":"R44-14-20210204","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1001\/jama.294.3.326","article-title":"Non-HDL cholesterol, apolipoproteins A-I and B100, standard lipid measures, lipid ratios, and CRP as risk factors for cardiovascular disease in women","volume":"294","author":"Ridker","year":"2005","journal-title":"JAMA"},{"key":"R45-14-20210204","doi-asserted-by":"crossref","first-page":"1512","DOI":"10.1016\/j.jacc.2008.02.034","article-title":"Lipoprotein management in patients with cardiometabolic risk: consensus conference report from the American Diabetes Association and the American College of Cardiology Foundation","volume":"51","author":"Brunzell","year":"2008","journal-title":"J Am Coll Cardiol"},{"key":"R46-14-20210204","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1016\/j.jacc.2007.10.038","article-title":"Impact of triglyceride levels beyond low-density lipoprotein cholesterol after acute coronary syndrome in the PROVE IT-TIMI 22 trial","volume":"51","author":"Miller","year":"2008","journal-title":"J Am Coll Cardiol"}],"container-title":["Current Opinion in Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/HCO.0b013e32832c1284","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,14]],"date-time":"2021-05-14T00:51:08Z","timestamp":1620953468000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00001573-200907000-00014"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,7]]},"references-count":46,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2009]]}},"URL":"https:\/\/doi.org\/10.1097\/hco.0b013e32832c1284","relation":{},"ISSN":["0268-4705"],"issn-type":[{"value":"0268-4705","type":"print"}],"subject":[],"published":{"date-parts":[[2009,7]]}}}