{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T16:44:59Z","timestamp":1761237899299},"reference-count":38,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,7]]},"DOI":"10.1097\/hco.0b013e328353bc4f","type":"journal-article","created":{"date-parts":[[2012,5,5]],"date-time":"2012-05-05T16:02:22Z","timestamp":1336233742000},"page":"374-380","source":"Crossref","is-referenced-by-count":20,"title":["Which, if any, antihypertensive agents cause cancer?"],"prefix":"10.1097","volume":"27","author":[{"given":"Amita","family":"Singh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sripal","family":"Bangalore","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R2-10-20210204","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1016\/S1470-2045(10)70106-6","article-title":"Angiotensin-receptor blockade and risk of cancer: meta-analysis of randomised controlled trials.","volume":"11","author":"Sipahi","year":"2010","journal-title":"Lancet Oncol"},{"key":"R3-10-20210204","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/S1470-2045(10)70260-6","article-title":"Antihypertensive drugs and risk of cancer: network meta-analyses and trial sequential analyses of 324168 participants from randomised trials.","volume":"12","author":"Bangalore","year":"2010","journal-title":"Lancet Oncol"},{"key":"R4-10-20210204","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/S0140-6736(76)92966-4","article-title":"Rauwolfia derivatives and breast cancer in hypertensive women.","volume":"2","author":"Armstrong","year":"1976","journal-title":"Lancet"},{"key":"R5-10-20210204","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/S0140-6736(75)92730-0","article-title":"Rauwolfia derivates and breast cancer.","volume":"306","author":"OFallon","year":"1975","journal-title":"Lancet"},{"key":"R6-10-20210204","first-page":"1090","article-title":"Does diuretic therapy increase the risk of renal cell carcinoma Am J C","volume":"83","author":"Grossman","year":"1999","journal-title":"ardiol"},{"key":"R7-10-20210204","doi-asserted-by":"crossref","first-page":"1964","DOI":"10.1093\/carcin\/bgq173","article-title":"Hypertension, diuretics and antihypertensives in relation to bladder cancer.","volume":"31","author":"Jiang","year":"2010","journal-title":"Carcinogenesis"},{"key":"R8-10-20210204","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1038\/nrc2945","article-title":"The renin-angiotensin system and cancer: old dog, new tricks.","volume":"10","author":"George","year":"2010","journal-title":"Nat Rev Cancer"},{"key":"R9-10-20210204","first-page":"293","article-title":"Angiotensin receptors: a new role in cancer Trends Endocrinol M","volume":"16","author":"Deshaves","year":"2005","journal-title":"etab"},{"key":"R10-10-20210204","doi-asserted-by":"crossref","first-page":"2635","DOI":"10.1200\/JCO.2010.33.5422","article-title":"Beta blockers and breast cancer mortality: a population based study.","volume":"29","author":"Barron","year":"2011","journal-title":"J Clin Oncol"},{"key":"R11-10-20210204","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1002\/ijc.25351","article-title":"Norepiphrine antagonists and cancer risk.","volume":"128","author":"Friedman","year":"2011","journal-title":"Int J Cancer"},{"key":"R12-10-20210204","first-page":"1957","article-title":"Calcium channel blockers, apoptosis and cancer: is there a biologic relationship J Am Coll C","volume":"34","author":"Mason","year":"1999","journal-title":"ardiol"},{"key":"R13-10-20210204","first-page":"695","article-title":"Do calcium channel blockers increase the risk of cancer Am J H","volume":"4","author":"Pahor","year":"1996","journal-title":"ypertens"},{"key":"R14-10-20210204","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1016\/S0140-6736(03)14283-3","article-title":"Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function taking angiotensin-converting enzyme inhibitors: the CHARM-Added Trial.","volume":"362","author":"McMurray","year":"2003","journal-title":"Lancet"},{"key":"R15-10-20210204","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1016\/S0140-6736(03)14282-1","article-title":"Effects of candesartan on mortality and morbidity in patients with chronic heart failure: The CHARM-Overall Program.","volume":"362","author":"Pfeffer","year":"2003","journal-title":"Lancet"},{"key":"R16-10-20210204","first-page":"351","article-title":"Cigarette smoking, obesity, diuretic use and coffee consumption as risk factors for renal cell carcinoma.","volume":"77","author":"Yu","year":"1986","journal-title":"J Natl Cancer Inst"},{"key":"R17-10-20210204","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1093\/jnci\/80.5.378","article-title":"Diuretics and renal cell cancer.","volume":"80","author":"McLaughlin","year":"1988","journal-title":"J Natl Cancer Inst"},{"key":"R19-10-20210204","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1038\/ki.1996.426","article-title":"Thiazide treatment of rats provokes apoptosis in distal tubule cells.","volume":"50","author":"Loffing","year":"1996","journal-title":"Kidney Int"},{"key":"R20-10-20210204","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1007\/s10552-005-0349-8","article-title":"A prospective study of body mass index, hypertension, and smoking and the risk of renal cell carcinoma.","volume":"16","author":"Flaherty","year":"2005","journal-title":"Cancer Causes Control"},{"key":"R21-10-20210204","doi-asserted-by":"crossref","first-page":"2981","DOI":"10.1001\/jama.288.23.2981","article-title":"Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs. diuretic.","volume":"288","year":"2002","journal-title":"JAMA"},{"key":"R22-10-20210204","doi-asserted-by":"crossref","first-page":"19","DOI":"10.4161\/cbt.10.1.11944","article-title":"Beta-2 adrenergic antagonists suppress pancreatic cancer cell invasion by inhibiting CREB, NFKB and AP-1.","volume":"10","author":"Zhang","year":"2010","journal-title":"Cancer Biol Ther"},{"key":"R23-10-20210204","doi-asserted-by":"crossref","first-page":"1615","DOI":"10.1007\/s10552-010-9590-x","article-title":"Hypertension, antihypertensive medication use, and breast cancer risk in the California Teachers Study Cohort.","volume":"21","author":"Largent","year":"2010","journal-title":"Cancer Causes Control"},{"key":"R24-10-20210204","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1136\/bmj.304.6824.405","article-title":"Medical Research Council Trial of treatment of hypertension in older adults: principal results.","volume":"304","year":"1992","journal-title":"BMJ"},{"key":"R25-10-20210204","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/S0002-9343(99)00447-7","article-title":"Calcium channel blockers and cancer.","volume":"108","author":"Cohen","year":"2000","journal-title":"Am J Med"},{"key":"R26-10-20210204","doi-asserted-by":"crossref","first-page":"3076","DOI":"10.1158\/1055-9965.EPI-08-0095","article-title":"Cardiovascular medication use and risk for colorectal cancer.","volume":"17","author":"Boudreau","year":"2008","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"R27-10-20210204","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1158\/1055-9965.EPI-03-0093","article-title":"Inverse association between prostate cancer and the use of calcium channel blockers.","volume":"13","author":"Debes","year":"2004","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"R28-10-20210204","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1111\/j.1440-1746.2006.04797.x","article-title":"Effect of ACE inhibitors and angiotensin II receptor antagonists in a mouse model of colorectal cancer liver metastases.","volume":"22","author":"Neo","year":"2007","journal-title":"J Gastroenterol Hepatol"},{"key":"R29-10-20210204","first-page":"1073","article-title":"The angiotensin-I-converting enzyme inhibitor perindopril suppresses tumor growth and angiogenesis: possible role of the vascular endothelial growth factor.","volume":"7","author":"Yoshiji","year":"2001","journal-title":"Clin Cancer Res"},{"key":"R30-10-20210204","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1007\/s00432-004-0582-7","article-title":"Effects of the angiotensin-I converting enzyme inhibitor perindopril on tumor growth and angiogenesis in head and neck squamous cell carcinoma cells.","volume":"130","author":"Yasumatsu","year":"2004","journal-title":"J Cancer Res Clin Oncol"},{"key":"R31-10-20210204","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1097\/MCG.0b013e3181ea1044","article-title":"Longterm use of angiotensin converting enzyme inhibitors is associated with decreased incidence of advanced adenomatous colon polyps.","volume":"45","author":"Kedika","year":"2011","journal-title":"J Clin Gastroenterol"},{"key":"R35-10-20210204","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1056\/NEJM199108013250501","article-title":"Effect of Enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure.","volume":"325","year":"1991","journal-title":"N Engl J Med"},{"key":"R36-10-20210204","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1097\/HJH.0b013e3282f3ef5e","article-title":"Antihypertensive medication and their impact on cancer incidence: a mixed treatment comparison meta-analysis of randomized controlled trials.","volume":"22","author":"Coleman","year":"2008","journal-title":"J Hypertens"},{"key":"R37-10-20210204","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1097\/HJH.0b013e328344a7de","article-title":"Effects of Telmisartan, Irbesartan, Valsartan, Candesartan, and Losartan on Cancers in 15 trials enrolling 138769 individuals.","volume":"29","author":"Trialists","year":"2011","journal-title":"J Hypertens"},{"key":"R38-10-20210204","doi-asserted-by":"crossref","first-page":"1644","DOI":"10.1038\/sj.bjc.6605955","article-title":"Inhibition of renin-angiotensin system affects prognosis of advanced pancreatic cancer receiving gemcitabine.","volume":"103","author":"Nakai","year":"2010","journal-title":"Br J Cancer"},{"key":"R39-10-20210204","doi-asserted-by":"crossref","first-page":"2061","DOI":"10.1096\/fj.03-0129com","article-title":"Differential regulation of in vivo angiogenesis by angiotensin II receptors.","volume":"17","author":"Walther","year":"2003","journal-title":"FASEB J"},{"key":"R40-10-20210204","doi-asserted-by":"crossref","first-page":"2279","DOI":"10.1002\/ijc.25234","article-title":"Deficiency or blockade of angiotensin II receptor delays tumorigenesis by inhibiting malignant cell proliferation and angiogenesis.","volume":"127","author":"Clere","year":"2010","journal-title":"Int J Cancer"},{"key":"R41-10-20210204","doi-asserted-by":"crossref","first-page":"3001","DOI":"10.1200\/JCO.2011.35.1908","article-title":"Angiotensin receptor blockade and risk of cancer in type 2 diabetes mellitus: a nationwide case-control study.","volume":"29","author":"Chang","year":"2011","journal-title":"J Clin Oncol"},{"key":"R42-10-20210204","doi-asserted-by":"crossref","first-page":"1729","DOI":"10.1161\/CIRCULATIONAHA.110.007336","article-title":"Use of angiotensin receptor blockers and the risk of cancer.","volume":"123","author":"Pasternak","year":"2011","journal-title":"Circulation"},{"key":"R44-10-20210204","first-page":"1","article-title":"Long-term use of drugs affecting the renin-angiotensin system and the risk of cancer: a population-based case-control study.","volume":"73","author":"Hallas","year":"2012","journal-title":"Br J Clin Pharmacol"}],"container-title":["Current Opinion in Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/HCO.0b013e328353bc4f","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,14]],"date-time":"2021-05-14T00:53:37Z","timestamp":1620953617000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00001573-201207000-00010"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,7]]},"references-count":38,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2012]]}},"URL":"https:\/\/doi.org\/10.1097\/hco.0b013e328353bc4f","relation":{},"ISSN":["0268-4705"],"issn-type":[{"value":"0268-4705","type":"print"}],"subject":[],"published":{"date-parts":[[2012,7]]}}}