{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T12:36:18Z","timestamp":1767962178587,"version":"3.49.0"},"reference-count":55,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,3]]},"DOI":"10.1097\/hco.0b013e32835dd020","type":"journal-article","created":{"date-parts":[[2013,1,23]],"date-time":"2013-01-23T11:53:38Z","timestamp":1358942018000},"page":"130-138","source":"Crossref","is-referenced-by-count":7,"title":["Hypertrophic cardiomyopathy"],"prefix":"10.1097","volume":"28","author":[{"given":"Ingegerd","family":"\u00d6stman-Smith","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph W.","family":"Rossano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert E.","family":"Shaddy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-8-20210204","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.1056\/NEJMoa021737","article-title":"The epidemiology of childhood cardiomyopathy in Australia.","volume":"348","author":"Nugent","year":"2003","journal-title":"N Engl J Med"},{"key":"R2-8-20210204","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.1056\/NEJMoa021715","article-title":"The incidence of pediatric cardiomyopathy in two regions of the United States.","volume":"348","author":"Lipshultz","year":"2003","journal-title":"N Engl J Med"},{"key":"R3-8-20210204","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1161\/CIRCULATIONAHA.108.804617","article-title":"Sudden deaths in young competitive athletes: analysis of 1866 deaths in the United States, 1980-2006.","volume":"119","author":"Maron","year":"2009","journal-title":"Circulation"},{"key":"R4-8-20210204","doi-asserted-by":"crossref","first-page":"1332","DOI":"10.1161\/CIRCULATIONAHA.104.530303","article-title":"Clinical features and outcomes of childhood hypertrophic cardiomyopathy: results from a national population-based study.","volume":"112","author":"Nugent","year":"2005","journal-title":"Circulation"},{"key":"R5-8-20210204","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1161\/CIRCULATIONAHA.106.621185","article-title":"Epidemiology and cause-specific outcome of hypertrophic cardiomyopathy in children: findings from the Pediatric Cardiomyopathy Registry.","volume":"115","author":"Colan","year":"2007","journal-title":"Circulation"},{"key":"R6-8-20210204","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1007\/s00246-011-9967-y","article-title":"Long-term follow-up of children and adolescents diagnosed with hypertrophic cardiomyopathy: risk factors for adverse arrhythmic events.","volume":"32","author":"Moak","year":"2011","journal-title":"Pediatr Cardiol"},{"key":"R7-8-20210204","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.1161\/CIRCULATIONAHA.106.174287","article-title":"Contemporary definitions and classification of the cardiomyopathies: an American Heart Association Scientific Statement from the Council on Clinical Cardiology, Heart Failure and Transplantation Committee; Quality of Care and Outcomes Research and Functional Genomics and Translational Biology Interdisciplinary Working Groups; and Council on Epidemiology and Prevention.","volume":"113","author":"Maron","year":"2006","journal-title":"Circulation"},{"key":"R8-8-20210204","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1161\/01.CIR.92.4.785","article-title":"Prevalence of hypertrophic cardiomyopathy in a general population of young adults. Echocardiographic analysis of 4111 subjects in the CARDIA Study. Coronary Artery Risk Development in (Young) Adults.","volume":"92","author":"Maron","year":"1995","journal-title":"Circulation"},{"key":"R9-8-20210204","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1016\/j.jacc.2012.02.068","article-title":"Genetics of hypertrophic cardiomyopathy after 20 years: clinical perspectives.","volume":"60","author":"Maron","year":"2012","journal-title":"J Am Coll Cardiol"},{"key":"R10-8-20210204","doi-asserted-by":"crossref","first-page":"1813","DOI":"10.1016\/S0735-1097(99)00421-0","article-title":"A cohort study of childhood hypertrophic cardiomyopathy: improved survival following high-dose beta-adrenoceptor antagonist treatment.","volume":"34","author":"Ostman-Smith","year":"1999","journal-title":"J Am Coll Cardiol"},{"key":"R11-8-20210204","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1017\/S1047951105001824","article-title":"Echocardiographic and electrocardiographic identification of those children with hypertrophic cardiomyopathy who should be considered at high-risk of dying suddenly.","volume":"15","author":"Ostman-Smith","year":"2005","journal-title":"Cardiol Young"},{"key":"R12-8-20210204","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/j.jacc.2009.03.051","article-title":"Risk factors and mode of death in isolated hypertrophic cardiomyopathy in children.","volume":"54","author":"Decker","year":"2009","journal-title":"J Am Coll Cardiol"},{"key":"R13-8-20210204","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1111\/j.1440-1754.2012.02450.x","article-title":"Clinicopathological features of fatal cardiomyopathy in childhood: an autopsy series.","volume":"48","author":"Roberts","year":"2012","journal-title":"J Paediatr Child Health"},{"key":"R14-8-20210204","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1111\/j.1472-8206.2010.00869.x","article-title":"Hypertrophic cardiomyopathy in childhood and adolescence - strategies to prevent sudden death.","volume":"24","author":"Ostman-Smith","year":"2010","journal-title":"Fundam Clin Pharmacol"},{"key":"R15-8-20210204","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1093\/eurheartj\/ehn122","article-title":"Age- and gender-specific mortality rates in childhood hypertrophic cardiomyopathy.","volume":"29","author":"Ostman-Smith","year":"2008","journal-title":"Eur Heart J"},{"key":"R16-8-20210204","doi-asserted-by":"crossref","first-page":"1388","DOI":"10.1161\/01.CIR.65.7.1388","article-title":"Sudden death in hypertrophic cardiomyopathy: a profile of 78 patients.","volume":"65","author":"Maron","year":"1982","journal-title":"Circulation"},{"key":"R17-8-20210204","doi-asserted-by":"crossref","first-page":"2406","DOI":"10.1016\/j.jacc.2011.07.044","article-title":"Mortality risk of untreated myosin-binding protein C-related hypertrophic cardiomyopathy: insight into the natural history.","volume":"58","author":"Nannenberg","year":"2011","journal-title":"J Am Coll Cardiol"},{"key":"R18-8-20210204","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1093\/europace\/eup431","article-title":"Risk stratification for sudden cardiac death in hypertrophic cardiomyopathy: systematic review of clinical risk markers.","volume":"12","author":"Christiaans","year":"2010","journal-title":"Europace"},{"key":"R19-8-20210204","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1093\/eurheartj\/ehp443","article-title":"Electrocardiographic amplitudes: a new risk factor for sudden death in hypertrophic cardiomyopathy.","volume":"31","author":"Ostman-Smith","year":"2010","journal-title":"Eur Heart J"},{"key":"R20-8-20210204","doi-asserted-by":"crossref","first-page":"1943","DOI":"10.1016\/S0735-1097(98)00493-8","article-title":"Long-term outcome and prognostic determinants in children with hypertrophic cardiomyopathy.","volume":"32","author":"Yetman","year":"1998","journal-title":"J Am Coll Cardiol"},{"issue":"Suppl","key":"R21-8-20210204","first-page":"S30","article-title":"ECG risk score: a significant advance in the risk stratification of paediatric patients with hypertrophic cardiomyopathy.","volume":"22","author":"Ostman-Smith","year":"2012","journal-title":"Cardiol Young"},{"key":"R22-8-20210204","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1007\/s00246-011-0106-6","article-title":"Restrictive physiology is associated with poor outcomes in children with hypertrophic cardiomyopathy.","volume":"33","author":"Maskatia","year":"2012","journal-title":"Pediatr Cardiol"},{"key":"R23-8-20210204","doi-asserted-by":"crossref","first-page":"2761","DOI":"10.1161\/CIR.0b013e318223e230","article-title":"2011ACCFAHA guideline for the diagnosis and treatment of hypertrophic cardiomyopathy: executive summary: a report of the American College of Cardiology FoundationAmerican Heart Association Task Force on Practice Guidelines.","volume":"124","author":"Gersh","year":"2011","journal-title":"Circulation"},{"key":"R24-8-20210204","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1097\/01.hjr.0000238393.96975.32","article-title":"Recommendations for participation in competitive sport and leisure-time physical activity in individuals with cardiomyopathies, myocarditis and pericarditis.","volume":"13","author":"Pelliccia","year":"2006","journal-title":"Eur J Cardiovasc Prev Rehabil"},{"key":"R25-8-20210204","doi-asserted-by":"crossref","first-page":"1593","DOI":"10.1001\/jama.296.13.1593","article-title":"Trends in sudden cardiovascular death in young competitive athletes after implementation of a preparticipation screening program.","volume":"296","author":"Corrado","year":"2006","journal-title":"JAMA"},{"key":"R26-8-20210204","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1056\/NEJMoa021332","article-title":"Effect of left ventricular outflow tract obstruction on clinical outcome in hypertrophic cardiomyopathy.","volume":"348","author":"Maron","year":"2003","journal-title":"N Engl J Med"},{"key":"R27-8-20210204","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1136\/heartjnl-2011-300531","article-title":"Hypertrophic cardiomyopathy in children.","volume":"98","author":"Moak","year":"2012","journal-title":"Heart"},{"key":"R28-8-20210204","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1111\/j.1747-0803.2011.00613.x","article-title":"Hypertrophic cardiomyopathy: infants, children, and adolescents.","volume":"7","author":"Maskatia","year":"2012","journal-title":"Congenit Heart Dis"},{"key":"R29-8-20210204","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1111\/j.1365-2125.2007.03046.x","article-title":"Population pharmacokinetics and dose simulation of carvedilol in paediatric patients with congestive heart failure.","volume":"65","author":"Albers","year":"2008","journal-title":"Br J Clin Pharmacol"},{"issue":"Suppl 1","key":"R30-8-20210204","doi-asserted-by":"crossref","first-page":"I41","DOI":"10.1007\/s003950070008","article-title":"Cardioprotection with beta-adrenoceptor blockers.","volume":"95","author":"Hjalmarson","year":"2000","journal-title":"Does lipophilicity matter Basic Res Cardiol"},{"key":"R31-8-20210204","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1016\/j.jacc.2005.05.053","article-title":"Reversal of inappropriate peripheral vascular responses in hypertrophic cardiomyopathy.","volume":"46","author":"Thaman","year":"2005","journal-title":"J Am Coll Cardiol"},{"key":"R32-8-20210204","doi-asserted-by":"crossref","first-page":"1424","DOI":"10.1016\/j.athoracsur.2005.03.109","article-title":"Septal myectomy for obstructive hypertrophic cardiomyopathy in pediatric patients: early and late results.","volume":"80","author":"Minakata","year":"2005","journal-title":"Ann Thorac Surg"},{"key":"R33-8-20210204","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1016\/j.athoracsur.2011.10.032","article-title":"Hypertrophic cardiomyopathy in childhood: disease natural history, impact of obstruction, and its influence on survival.","volume":"93","author":"Hickey","year":"2012","journal-title":"Ann Thorac Surg"},{"key":"R34-8-20210204","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/j.hfc.2010.05.004","article-title":"Hypertrophic cardiomyopathy in childhood.","volume":"6","author":"Colan","year":"2010","journal-title":"Heart Fail Clin"},{"key":"R35-8-20210204","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1017\/S1047951100006818","article-title":"Verapamil therapy in infants with hypertrophic cardiomyopathy.","volume":"8","author":"Moran","year":"1998","journal-title":"Cardiol Young"},{"key":"R36-8-20210204","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1016\/j.jacc.2005.01.012","article-title":"Multicenter study of the efficacy and safety of disopyramide in obstructive hypertrophic cardiomyopathy.","volume":"45","author":"Sherrid","year":"2005","journal-title":"J Am Coll Cardiol"},{"key":"R37-8-20210204","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1016\/j.jacc.2005.02.090","article-title":"Long-term effects of surgical septal myectomy on survival in patients with obstructive hypertrophic cardiomyopathy.","volume":"46","author":"Ommen","year":"2005","journal-title":"J Am Coll Cardiol"},{"key":"R38-8-20210204","doi-asserted-by":"crossref","first-page":"2080","DOI":"10.1093\/eurheartj\/ehs064","article-title":"A contemporary European experience with surgical septal myectomy in hypertrophic cardiomyopathy.","volume":"33","author":"Iacovoni","year":"2012","journal-title":"Eur Heart J"},{"key":"R39-8-20210204","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/j.jtcvs.2003.09.040","article-title":"Extended septal myectomy for hypertrophic obstructive cardiomyopathy with anomalous mitral papillary muscles or chordae.","volume":"127","author":"Minakata","year":"2004","journal-title":"J Thorac Cardiovasc Surg"},{"key":"R40-8-20210204","doi-asserted-by":"crossref","first-page":"2501","DOI":"10.1016\/j.jacc.2011.09.020","article-title":"Percutaneous radiofrequency septal reduction for hypertrophic obstructive cardiomyopathy in children.","volume":"58","author":"Sreeram","year":"2011","journal-title":"J Am Coll Cardiol"},{"key":"R41-8-20210204","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.ijcard.2005.02.009","article-title":"Nonsurgical septal reduction for hypertrophic cardiomyopathy in childhood.","volume":"106","author":"Subash Chandra","year":"2006","journal-title":"Int J Cardiol"},{"key":"R42-8-20210204","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1016\/j.healun.2009.05.028","article-title":"Outcomes of pediatric patients with hypertrophic cardiomyopathy listed for transplant.","volume":"28","author":"Gajarski","year":"2009","journal-title":"J Heart Lung Transplant"},{"key":"R43-8-20210204","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1161\/CIRCHEARTFAILURE.109.922872","article-title":"Survival after cardiac transplantation in patients with hypertrophic cardiomyopathy.","volume":"3","author":"Maron","year":"2010","journal-title":"Circ Heart Fail"},{"key":"R44-8-20210204","doi-asserted-by":"crossref","first-page":"1596","DOI":"10.1016\/S0735-1097(99)00056-X","article-title":"Survival after cardiac arrest or sustained ventricular tachycardia in patients with hypertrophic cardiomyopathy.","volume":"33","author":"Elliott","year":"1999","journal-title":"J Am Coll Cardiol"},{"key":"R45-8-20210204","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1001\/jama.298.4.405","article-title":"Implantable cardioverter-defibrillators and prevention of sudden cardiac death in hypertrophic cardiomyopathy.","volume":"298","author":"Maron","year":"2007","journal-title":"JAMA"},{"key":"R46-8-20210204","doi-asserted-by":"crossref","first-page":"1118","DOI":"10.1111\/j.1540-8167.2008.01147.x","article-title":"Implantable defibrillators and prevention of sudden death in hypertrophic cardiomyopathy.","volume":"19","author":"Maron","year":"2008","journal-title":"J Cardiovasc Electrophysiol"},{"key":"R47-8-20210204","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1136\/hrt.2010.217182","article-title":"The long-term survival and the risks and benefits of implantable cardioverter defibrillators in patients with hypertrophic cardiomyopathy.","volume":"98","author":"OMahony","year":"2012","journal-title":"Heart"},{"key":"R48-8-20210204","doi-asserted-by":"crossref","first-page":"3084","DOI":"10.1093\/eurheartj\/ehq308","article-title":"Sudden death in hypertrophic cardiomyopathy: old risk factors re-assessed in a new model of maximalized follow-up.","volume":"31","author":"Dimitrow","year":"2010","journal-title":"Eur Heart J"},{"key":"R49-8-20210204","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1016\/S0735-1097(03)00827-1","article-title":"Nonsustained ventricular tachycardia in hypertrophic cardiomyopathy: an independent marker of sudden death risk in young patients.","volume":"42","author":"Monserrat","year":"2003","journal-title":"J Am Coll Cardiol"},{"key":"R50-8-20210204","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.jacc.2009.02.071","article-title":"Outcome of patients with hypertrophic cardiomyopathy and a normal electrocardiogram.","volume":"54","author":"McLeod","year":"2009","journal-title":"J Am Coll Cardiol"},{"key":"R51-8-20210204","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1111\/j.1540-8167.2009.01716.x","article-title":"Implantable cardioverter-defibrillator in patients with hypertrophic cardiomyopathy: efficacy and complications of the therapy in long-term follow-up.","volume":"21","author":"Syska","year":"2010","journal-title":"J Cardiovasc Electrophysiol"},{"key":"R52-8-20210204","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1136\/hrt.2006.094730","article-title":"Outcomes after implantable cardioverter-defibrillator treatment in children with hypertrophic cardiomyopathy.","volume":"93","author":"Kaski","year":"2007","journal-title":"Heart"},{"key":"R53-8-20210204","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1093\/europace\/euq263","article-title":"Long-term follow-up of children and young adults treated with implantable cardioverter-defibrillator: the authors own experience with optimal implantable cardioverter-defibrillator programming.","volume":"12","author":"Lewandowski","year":"2010","journal-title":"Europace"},{"issue":"Suppl 1","key":"R54-8-20210204","first-page":"60","article-title":"Frequency of diagnostic ECG-abnormalities in children of parents with familial hypertrophic cardiomyopathy.","volume":"17","author":"Ostman-Smith","year":"2007","journal-title":"Cardiol Young"},{"key":"R55-8-20210204","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1016\/j.ehj.2003.10.031","article-title":"Diagnostic value of abnormal Q-waves for identification of preclinical carriers of hypertrophic cardiomyopathy based on a molecular genetic diagnosis.","volume":"25","author":"Konno","year":"2004","journal-title":"Eur Heart J"}],"container-title":["Current Opinion in Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/HCO.0b013e32835dd020","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,5]],"date-time":"2024-05-05T03:29:30Z","timestamp":1714879770000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00001573-201303000-00008"}},"subtitle":["do sudden death prevention strategies in children differ between Europe and North America?"],"short-title":[],"issued":{"date-parts":[[2013,3]]},"references-count":55,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013]]}},"URL":"https:\/\/doi.org\/10.1097\/hco.0b013e32835dd020","relation":{},"ISSN":["0268-4705"],"issn-type":[{"value":"0268-4705","type":"print"}],"subject":[],"published":{"date-parts":[[2013,3]]}}}