{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T13:01:35Z","timestamp":1791810095754,"version":"4.3.4"},"reference-count":39,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2007,7]]},"DOI":"10.1097\/hjh.0b013e3281139ea9","type":"journal-article","created":{"date-parts":[[2007,6,11]],"date-time":"2007-06-11T04:03:26Z","timestamp":1181534606000},"page":"1459-1464","source":"Crossref","is-referenced-by-count":48,"title":["Periodontal disease severity is related to high levels of C-reactive protein in pre-eclampsia"],"prefix":"10.1097","volume":"25","author":[{"given":"Juli\u00e1n A","family":"Herrera","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatriz","family":"Parra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enrique","family":"Herrera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier E","family":"Botero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roger M","family":"Arce","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adolfo","family":"Contreras","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricio","family":"L\u00f3pez-Jaramillo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-23-20210208","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1054\/mehy.2001.1378","article-title":"Is infection a major risk factor for preeclampsia?","volume":"57","author":"Herrera","year":"2001","journal-title":"Med Hypotheses"},{"key":"R2-23-20210208","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1128\/CMR.13.4.547","article-title":"Systemic diseases caused by oral infection","volume":"13","author":"Li","year":"2000","journal-title":"Clin Microbiol Rev"},{"issue":"Suppl","key":"R3-23-20210208","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1902\/jop.1996.67.10s.1103","article-title":"Periodontal infection as a possible risk factor for preterm low birth weight","volume":"67","author":"Offenbacher","year":"1996","journal-title":"J Periodontol"},{"key":"R4-23-20210208","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1177\/002203450208100113","article-title":"Higher risk of preterm birth and low birth weight in women with periodontal disease","volume":"81","author":"Lopez","year":"2002","journal-title":"J Dent Res"},{"key":"R5-23-20210208","first-page":"227","article-title":"Maternal periodontal disease is associated with an increased risk for preeclampsia","volume":"101","author":"Boggess","year":"2003","journal-title":"Obstet Gynecol"},{"key":"R6-23-20210208","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1111\/j.1479-828X.2004.00323.x","article-title":"Periodontal disease as a risk factor for pre-eclampsia: a case control study","volume":"44","author":"Canakci","year":"2004","journal-title":"Aust NZ J Obstet Gynaecol"},{"key":"R7-23-20210208","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1902\/jop.2005.76.1.134","article-title":"Severe pregnancy complication (preeclampsia) is associated with greater periodontal destruction","volume":"76","author":"Oettinger-Barak","year":"2005","journal-title":"J Periodontol"},{"key":"R8-23-20210208","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1902\/jop.2006.050020","article-title":"Periodontitis is associated with preeclampsia in pregnant women","volume":"77","author":"Contreras","year":"2006","journal-title":"J Periodontol"},{"key":"R9-23-20210208","doi-asserted-by":"crossref","first-page":"1955","DOI":"10.1161\/01.CIR.0000125690.80303.A8","article-title":"Clinical usefulness of very high and very low levels of C-reactive protein across the full range of Framingham Risk Scores","volume":"109","author":"Ridker","year":"2004","journal-title":"Circulation"},{"key":"R10-23-20210208","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1053\/j.ajkd.2005.10.028","article-title":"C-reactive protein: a family of proteins to regulate cardiovascular function","volume":"47","author":"Schwedler","year":"2006","journal-title":"Am J Kidney Dis"},{"key":"R11-23-20210208","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.ejogrb.2004.12.009","article-title":"Association of fibrinogen and C-reactive protein with severity of preeclampsia","volume":"121","author":"Ustun","year":"2005","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"R12-23-20210208","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1080\/00016340500432614","article-title":"The role of C-reactive protein in modern obstetric and gynecological practice","volume":"85","author":"Azizia","year":"2006","journal-title":"Acta Obstet Gynecol Scand"},{"key":"R13-23-20210208","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/0301-2115(95)02334-8","article-title":"Caravalho-Guerra, Pereira-Leite L, Quintnhila A. Comparative study of lactoferrin and other blood markers of inflammatory stress between preeclamptic and normal pregnancies.","volume":"64","author":"Rebelo","year":"1996","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"R14-23-20210208","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/S0020-7292(01)00499-4","article-title":"Elevated C-reactive protein and pro-inflammatory cytokines in Andean women with pre-eclampsia","volume":"75","author":"Teran","year":"2001","journal-title":"Int J Gynaecol Obstet"},{"key":"R15-23-20210208","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1093\/aje\/kwi334","article-title":"Inflammation and triglycerides partially mediate the effect of prepregnancy body mass index on the risk of preeclampsia","volume":"162","author":"Bodnar","year":"2005","journal-title":"Am J Epidemiol"},{"key":"R16-23-20210208","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.amjhyper.2003.09.011","article-title":"A prospective study of maternal serum C-reactive protein concentrations and risk of preeclampsia","volume":"17","author":"Qiu","year":"2004","journal-title":"Am J Hypertens"},{"key":"R17-23-20210208","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1902\/annals.1999.4.1.1","article-title":"Development of a classification system for periodontal diseases and conditions","volume":"4","author":"Armitage","year":"1999","journal-title":"Ann Periodontol"},{"issue":"Suppl","key":"R18-23-20210208","first-page":"380","article-title":"Microbiological examination of root canals and periapical tissues of human teeth. Methodological studies","volume":"74","author":"Moller","year":"1966","journal-title":"Odontol Tidskr"},{"key":"R19-23-20210208","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1128\/JCM.37.1.171-174.1999","article-title":"Proficiencies of three anaerobic culture systems for recovering periodontal pathogenic bacteria","volume":"37","author":"Doan","year":"1999","journal-title":"J Clin Microbiol"},{"key":"R20-23-20210208","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1111\/j.1399-302X.1986.tb00318.x","article-title":"Rapid identification of important periodontal microorganisms by cultivation","volume":"1","author":"Slots","year":"1986","journal-title":"Oral Microbiol Immunol"},{"key":"R21-23-20210208","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1128\/JCM.16.6.1148-1151.1982","article-title":"Long-wave UV light fluorescence for identification of black-pigmented Bacteroides spp","volume":"16","author":"Slots","year":"1982","journal-title":"J Clin Microbiol"},{"key":"R22-23-20210208","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1111\/j.1399-302X.1992.tb00034.x","article-title":"Enterococci in human periodontitis","volume":"7","author":"Rams","year":"1992","journal-title":"Oral Microbiol Immunol"},{"key":"R23-23-20210208","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1111\/j.1600-051X.1998.tb02419.x","article-title":"Microbial complexes in subgingival plaque","volume":"25","author":"Socransky","year":"1998","journal-title":"J Clin Periodontol"},{"key":"R24-23-20210208","doi-asserted-by":"crossref","first-page":"S528","DOI":"10.1016\/S0002-8703(99)70293-0","article-title":"Dental infections and atherosclerosis","volume":"138","author":"Beck","year":"1999","journal-title":"Am Heart J"},{"key":"R25-23-20210208","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1902\/annals.1998.3.1.127","article-title":"Periodontitis: a risk factor for coronary heart disease?","volume":"3","author":"Beck","year":"1998","journal-title":"Ann Periodontol"},{"key":"R26-23-20210208","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1034\/j.1600-051x.2001.028009865.x","article-title":"On the association between hypercholesterolemia, cardiovascular disease and severe periodontal disease","volume":"28","author":"Katz","year":"2001","journal-title":"J Clin Periodontol"},{"key":"R27-23-20210208","doi-asserted-by":"crossref","first-page":"5792","DOI":"10.1128\/IAI.67.11.5792-5798.1999","article-title":"Invasion of human coronary artery cells by periodontal pathogens","volume":"67","author":"Dorn","year":"1999","journal-title":"Infect Immun"},{"key":"R28-23-20210208","doi-asserted-by":"crossref","first-page":"1554","DOI":"10.1902\/jop.2000.71.10.1554","article-title":"Identification of periodontal pathogens in atheromatous plaques","volume":"71","author":"Haraszthy","year":"2000","journal-title":"J Periodontol"},{"key":"R29-23-20210208","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1016\/S0002-9378(98)70160-7","article-title":"Etiology and pathogenesis of preeclampsia: current concepts","volume":"179","author":"Dekker","year":"1998","journal-title":"Am J Obstet Gynecol"},{"key":"R30-23-20210208","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1111\/j.1600-051X.1982.tb02108.x","article-title":"Patterns of progression and regression of advanced destructive periodontal disease","volume":"9","author":"Goodson","year":"1982","journal-title":"J Clin Periodontol"},{"key":"R31-23-20210208","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1902\/annals.2001.6.1.175","article-title":"Maternal periodontitis and prematurity. Part II: maternal infection and fetal exposure","volume":"6","author":"Madianos","year":"2001","journal-title":"Ann Periodontol"},{"key":"R32-23-20210208","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1902\/annals.2001.6.1.164","article-title":"Maternal periodontitis and prematurity. Part I: obstetric outcome of prematurity and growth restriction","volume":"6","author":"Offenbacher","year":"2001","journal-title":"Ann Periodontol"},{"key":"R33-23-20210208","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/S0146-0005(00)80050-6","article-title":"Preeclampsia: what we know and what we do not know","volume":"24","author":"Roberts","year":"2000","journal-title":"Semin Perinatol"},{"key":"R34-23-20210208","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1097\/01.hjh.0000170371.49010.4a","article-title":"Preventing pregnancy-induced hypertension: are there regional differences for this global problem?","volume":"23","author":"Lopez-Jaramillo","year":"2005","journal-title":"J Hypertens"},{"key":"R35-23-20210208","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1111\/j.1600-0897.1997.tb00222.x","article-title":"Placental cytokines and the pathogenesis of preeclampsia","volume":"37","author":"Conrad","year":"1997","journal-title":"Am J Reprod Immunol"},{"key":"R36-23-20210208","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/S0002-9378(99)70239-5","article-title":"Preeclampsia: an excessive maternal inflammatory response to pregnancy","volume":"180","author":"Redman","year":"1999","journal-title":"Am J Obstet Gynecol"},{"key":"R37-23-20210208","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/S0301-2115(00)00493-0","article-title":"Pre-eclampsia and the inflammatory response","volume":"95","author":"Faas","year":"2001","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"R38-23-20210208","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1034\/j.1600-0412.2002.810710.x","article-title":"Could an infectious trigger explain the differential maternal response to the shared placental pathology of preeclampsia and normotensive intrauterine growth restriction?","volume":"81","author":"von","year":"2002","journal-title":"Acta Obstet Gynecol Scand"},{"key":"R39-23-20210208","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.amjhyper.2006.06.001","article-title":"Raised C-reactive protein and impaired flow mediated vasodilation precede the development of preeclampsia","volume":"20","author":"Garc\u00eda","year":"2007","journal-title":"Am J Hypertens"}],"container-title":["Journal of Hypertension"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00004872-200707000-00023","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T16:43:27Z","timestamp":1786034607000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00004872-200707000-00023"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,7]]},"references-count":39,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2007]]}},"URL":"https:\/\/doi.org\/10.1097\/hjh.0b013e3281139ea9","relation":{},"ISSN":["0263-6352"],"issn-type":[{"value":"0263-6352","type":"print"}],"subject":[],"published":{"date-parts":[[2007,7]]}}}