{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,7]],"date-time":"2025-05-07T04:20:10Z","timestamp":1746591610428,"version":"3.40.5"},"reference-count":27,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:sec>\n            <jats:title>Background:<\/jats:title>\n            <jats:p>Baseline biomarkers including glomerular filtration rate (GFR) guide the management of patients with ST-segment elevation myocardial infarction (STEMI). GFR is a tool for prediction of adverse outcomes in these patients.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Objectives:<\/jats:title>\n            <jats:p>We aimed to determine the prognostic utility of estimated GFR using Chronic Kidney Disease Epidemiology Collaboration in a cohort of STEMI patients.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods:<\/jats:title>\n            <jats:p>A retrospective cohort was designed among 5953 patients with STEMI. Primary endpoint of the study was major adverse cardiovascular events. GFR was classified into 3 categories delineated as C1 (&lt;60 mL\/min), C2 (60\u201390), and C3 (\u2265 90).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results:<\/jats:title>\n            <jats:p>Mean age of the patients was 60.38 \u00b1 5.54 years and men constituted 78.8% of the study participants. After a median of 22 months, Multivariate Cox-regression demonstrated that hazards of major averse cardiovascular event, all-cause mortality, cardiovascular mortality, and nonfatal myocardial infarction were significantly lower for subjects in C3 as compared with those in C1. Corresponding hazard ratios (HRs) for mentioned outcomes regarding C3 versus C1 were (95% confidence interval) were (HR = 0.852 [0.656\u20130.975]; <jats:italic toggle=\"yes\">P<\/jats:italic> = 0.035), (HR = 0.425 [0.250\u20130.725]; <jats:italic toggle=\"yes\">P<\/jats:italic> = 0.002), (HR = 0.425 [0.242\u20130.749]; <jats:italic toggle=\"yes\">P<\/jats:italic> = 0.003), and (0.885 [0.742\u20130.949]; <jats:italic toggle=\"yes\">P<\/jats:italic> = 0.003), respectively. Normal GFR was also associated with declined in-hospital mortality with HR of C3 versus C1: 0.299 (0.178\u20130.504; <jats:italic toggle=\"yes\">P<\/jats:italic> &lt; 0.0001).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions:<\/jats:title>\n            <jats:p>Baseline GFR via Chronic Kidney Disease Epidemiology Collaboration is associated with long-term cardiovascular outcomes following STEMI.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/hpc.0000000000000296","type":"journal-article","created":{"date-parts":[[2022,8,22]],"date-time":"2022-08-22T21:00:49Z","timestamp":1661202049000},"page":"153-159","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Impact of Baseline Estimated Glomerular Filtration Rate Using CKD-EPI Equation on Long-term Prognosis of STEMI Patients: A Matter of Small Increments!"],"prefix":"10.1097","volume":"21","author":[{"given":"Seyed-Ali","family":"Sadre-Bafghi","sequence":"first","affiliation":[{"name":"Afshar Hospital, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehrnaz","family":"Mohebi","sequence":"additional","affiliation":[{"name":"Research Department, Tehran Heart Center, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatemeh","family":"Hadi","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Imam Hossein Medical Center, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanieh","family":"Parsaiyan","sequence":"additional","affiliation":[{"name":"Research Department, Tehran Heart Center, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammadreza","family":"Memarjafari","sequence":"additional","affiliation":[{"name":"Research Department, Tehran Heart Center, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roya","family":"Tayeb","sequence":"additional","affiliation":[{"name":"Research Department, Tehran Heart Center, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saeed","family":"Ghodsi","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reza","family":"Sheikh-Sharbafan","sequence":"additional","affiliation":[{"name":"Research Department, Tehran Heart Center, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hamidreza","family":"Poorhosseini","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Tehran Heart Center, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mojtaba","family":"Salarifar","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Tehran Heart Center, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad","family":"Alidoosti","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Tehran Heart Center, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali-Mohammad","family":"Haji-Zeinali","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Tehran Heart Center, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alireza","family":"Amirzadegan","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Tehran Heart Center, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hassan","family":"Aghajani","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Tehran Heart Center, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yaser","family":"Jenab","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Tehran Heart Center, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zahra","family":"Hosseini","sequence":"additional","affiliation":[{"name":"Research Department, Tehran Heart Center, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","published-online":{"date-parts":[[2022,6,29]]},"reference":[{"key":"R1-20250506","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S0140-6736(03)12113-7","article-title":"Primary angioplasty versus intravenous thrombolytic therapy for acute myocardial infarction: a quantitative review of 23 randomised trials.","volume":"361","author":"Keeley","year":"2003","journal-title":"Lancet"},{"key":"R2-20250506","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1007\/s11886-017-0840-3","article-title":"Prognostic biomarkers in acute coronary syndromes: risk stratification beyond cardiac 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