{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:22:11Z","timestamp":1786119731723,"version":"build-2736575974"},"reference-count":37,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,3]]},"DOI":"10.1097\/htr.0b013e31820e6840","type":"journal-article","created":{"date-parts":[[2011,3,25]],"date-time":"2011-03-25T16:17:15Z","timestamp":1301069835000},"page":"123-134","source":"Crossref","is-referenced-by-count":13,"title":["Clinical Utility of the Protein S100B to Evaluate Traumatic Brain Injury in the Presence of Acute Alcohol Intoxication"],"prefix":"10.1097","volume":"27","author":[{"given":"Rael T.","family":"Lange","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grant L.","family":"Iverson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey R.","family":"Brubacher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"issue":"2","key":"R1-6-20210129","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1097\/MCC.0b013e3282f57564","article-title":"Biomarkers of primary and evolving damage in traumatic and ischemic brain injury: diagnosis, prognosis, probing mechanisms, and therapeutic decision making.","volume":"14","author":"Kochanek","year":"2008","journal-title":"Curr Opin Crit Care"},{"issue":"3-4","key":"R2-6-20210129","first-page":"171","article-title":"Biochemical serum markers for brain damage: a short review with emphasis on clinical utility in mild head injury.","volume":"21","author":"Ingebrigtsen","year":"2003","journal-title":"Restor Neurol Neurosci"},{"key":"R3-6-20210129","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1007\/978-1-59745-562-6_3","article-title":"Clinical and model research of neurotrauma.","volume":"566","author":"Buki","year":"2009","journal-title":"Methods Mol Biol"},{"issue":"3","key":"R4-6-20210129","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1034\/j.1600-0404.2001.103003175.x","article-title":"S-100B and neuron-specific enolase in serum of mild traumatic brain injury patients. A comparison with health controls.","volume":"103","author":"de Kruijk","year":"2001","journal-title":"Acta Neurol Scand"},{"issue":"1","key":"R5-6-20210129","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/s002680020370","article-title":"Evaluation of S-100b as a specific marker for neuronal damage due to minor head trauma.","volume":"25","author":"Biberthaler","year":"2001","journal-title":"World J Surg"},{"issue":"7","key":"R6-6-20210129","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1080\/02699050310001646215","article-title":"S100 in mild traumatic brain injury.","volume":"18","author":"Nygren De Boussard","year":"2004","journal-title":"Brain Inj"},{"issue":"6","key":"R7-6-20210129","doi-asserted-by":"crossref","first-page":"1452","DOI":"10.1097\/TA.0b013e318047bfaa","article-title":"S100B serum level predicts computed tomography findings after minor head injury.","volume":"62","author":"Muller","year":"2007","journal-title":"J Trauma"},{"issue":"4","key":"R8-6-20210129","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1097\/HTR.0b013e3181e57e22","article-title":"Can low serum levels of S100B predict normal CT findings after minor head injury in adults: an evidence-based review and meta-analysis.","volume":"25","author":"Unden","year":"2010","journal-title":"J Head Trauma Rehabil"},{"issue":"2-3","key":"R9-6-20210129","first-page":"109","article-title":"Protein S-100B and neuron specific enolase as early neurobiochemical markers of the severity of traumatic brain injury.","volume":"14","author":"Herrmann","year":"1999","journal-title":"Restor Neurol Neurosci"},{"issue":"1","key":"R10-6-20210129","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1136\/jnnp.70.1.95","article-title":"Release of biochemical markers of damage to neuronal and glial brain tissue is associated with short and long term neuropsychological outcome after traumatic brain injury.","volume":"70","author":"Herrmann","year":"2001","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"3","key":"R11-6-20210129","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1111\/j.1600-0404.2009.01196.x","article-title":"Outcome prediction in traumatic brain injury: comparison of neurological status, CT findings, and blood levels of S100B and GFAP.","volume":"121","author":"Wiesmann","year":"2010","journal-title":"Acta Neurol Scand"},{"issue":"5","key":"R12-6-20210129","first-page":"542","article-title":"Head injury outcome prediction in the emergency department: a role for protein S-100B J Neurol Neurosurg Psychiatry.","volume":"73","author":"Townend","year":"2002","journal-title":""},{"issue":"8","key":"R14-6-20210129","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.1089\/0897715041651088","article-title":"Elevated serum S-100B protein as a predictor of failure to short-term return to work or activities after mild head injury.","volume":"21","author":"Stranjalis","year":"2004","journal-title":"J Neurotrauma"},{"issue":"4","key":"R15-6-20210129","doi-asserted-by":"crossref","first-page":"e697","DOI":"10.1542\/peds.2008-1493","article-title":"Relationship of serum S100B levels and intracranial injury in children with closed head trauma.","volume":"124","author":"Bechtel","year":"2009","journal-title":"Pediatrics"},{"issue":"4","key":"R16-6-20210129","doi-asserted-by":"crossref","first-page":"339","DOI":"10.3171\/2009.5.PEDS08481","article-title":"Diagnostic value of S100B and neuron-specific enolase in mild pediatric traumatic brain injury.","volume":"4","author":"Geyer","year":"2009","journal-title":"J Neurosurg Pediatr"},{"issue":"1","key":"R17-6-20210129","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1159\/000083678","article-title":"S-100B concentration is not related to neurocognitive performance in the first month after mild traumatic brain injury.","volume":"53","author":"Stapert","year":"2005","journal-title":"Eur Neurol"},{"issue":"1","key":"R18-6-20210129","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1080\/16501970410015587","article-title":"S100 and cognitive impairment after mild traumatic brain injury.","volume":"37","author":"de Boussard","year":"2005","journal-title":"J Rehabil Med"},{"issue":"5","key":"R19-6-20210129","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1080\/16501970510032910","article-title":"One-year follow-up of mild traumatic brain injury: postconcussion symptoms, disabilities, and life satisfaction in relation to serum levels of S-100B and neurone-specific enolase in acute phase.","volume":"37","author":"Stalnacke","year":"2005","journal-title":"J Rehabil Med"},{"issue":"7","key":"R23-6-20210129","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1089\/neu.2008.0586","article-title":"Classification of traumatic brain injury for targeted therapies.","volume":"25","author":"Saatman","year":"2008","journal-title":"J Neurotrauma"},{"issue":"5","key":"R24-6-20210129","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1089\/089771504774129900","article-title":"The effects of admission alcohol level on cerebral blood flow and outcomes after severe traumatic brain injury.","volume":"21","author":"Alexander","year":"2004","journal-title":"J Neurotrauma"},{"issue":"2","key":"R25-6-20210129","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1053\/ajem.2003.50025","article-title":"Alcohol intoxication increases morbidity in drivers involved in motor vehicle accidents.","volume":"21","author":"Shih","year":"2003","journal-title":"Am J Emerg Med"},{"issue":"6","key":"R26-6-20210129","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1097\/01.ta.0000240113.13552.96","article-title":"Waiting for the patient to sober up: effect of alcohol intoxication on Glasgow coma scale score of brain injured patients.","volume":"61","author":"Sperry","year":"2006","journal-title":"J Trauma"},{"issue":"4","key":"R27-6-20210129","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1097\/01.sla.0000250413.41265.d3","article-title":"Effect of alcohol on Glasgow Coma Scale in head-injured patients.","volume":"245","author":"Stuke","year":"2007","journal-title":"Ann Surg"},{"issue":"7-8","key":"R28-6-20210129","doi-asserted-by":"crossref","first-page":"919","DOI":"10.3109\/02699052.2010.489794","article-title":"Effect of blood alcohol level on Glasgow Coma Scale scores following traumatic brain injury.","volume":"24","author":"Lange","year":"2010","journal-title":"Brain Inj"},{"key":"R29-6-20210129","first-page":"177","article-title":"Influence of alcohol exposure on S-100b serum levels.","volume":"76","author":"Biberthaler","year":"2000","journal-title":"Acta Neurochir Suppl"},{"issue":"2","key":"R30-6-20210129","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1097\/00024382-200116020-00002","article-title":"Elevated serum levels of S-100B reflect the extent of brain injury in alcohol intoxicated patients after mild head trauma.","volume":"16","author":"Biberthaler","year":"2001","journal-title":"Shock"},{"issue":"6","key":"R31-6-20210129","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1111\/j.1468-1331.2005.00996.x","article-title":"The influence of alcohol and time on the S-100B levels of patients with minor head injury.","volume":"12","author":"Enochsson","year":"2005","journal-title":"Eur J Neurol"},{"issue":"5","key":"R32-6-20210129","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1097\/00024382-200211000-00002","article-title":"Immediate S-100B and neuron-specific enolase plasma measurements for rapid evaluation of primary brain damage in alcohol-intoxicated, minor head-injured patients.","volume":"18","author":"Mussack","year":"2002","journal-title":"Shock"},{"issue":"5","key":"R33-6-20210129","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1097\/TA.0b013e3181bb9890","article-title":"Differential effects of alcohol intoxication on S100B levels following traumatic brain injury.","volume":"68","author":"Lange","year":"2010","journal-title":"J Trauma"},{"issue":"3","key":"R34-6-20210129","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1227\/00006123-199009000-00014","article-title":"Mild head injury classification.","volume":"27","author":"Williams","year":"1990","journal-title":"Neurosurgery"},{"issue":"1","key":"R36-6-20210129","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1177\/1073191105285210","article-title":"California verbal learning test indicators of malingered neurocognitive dysfunction: sensitivity and specificity in traumatic brain injury.","volume":"13","author":"Curtis","year":"2006","journal-title":"Assessment"},{"issue":"4","key":"R37-6-20210129","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1177\/1073191105281099","article-title":"WAIS digit span-based indicators of malingered neurocognitive dysfunction: classification accuracy in traumatic brain injury.","volume":"12","author":"Heinly","year":"2005","journal-title":"Assessment"},{"issue":"3","key":"R39-6-20210129","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1080\/13854040590967144","article-title":"Sensitivity and specificity of MMPI-2 validity scales and indicators to malingered neurocognitive dysfunction in traumatic brain injury.","volume":"20","author":"Greve","year":"2006","journal-title":"Clin Neuropsychol"},{"issue":"10","key":"R40-6-20210129","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1111\/j.1468-1331.2009.02653.x","article-title":"Serum S100B protein in early management of patients after mild traumatic brain injury.","volume":"16","author":"Morochovic","year":"2009","journal-title":"Eur J Neurol"},{"issue":"2","key":"R41-6-20210129","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/S0003-9993(97)90253-7","article-title":"Systematic bias in outcome studies of persons with traumatic brain injury.","volume":"78","author":"Corrigan","year":"1997","journal-title":"Arch Phys Med Rehabil"},{"issue":"2","key":"R42-6-20210129","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1053\/apmr.2003.50093","article-title":"Systematic bias in traumatic brain injury outcome studies because of loss to follow up.","volume":"84","author":"Corrigan","year":"2003","journal-title":"Arch Phys Med Rehabil"},{"issue":"9","key":"R43-6-20210129","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1089\/neu.2008.0753","article-title":"Pediatric brain trauma outcome prediction using paired serum levels of inflammatory mediators and brain-specific proteins.","volume":"26","author":"Lo","year":"2009","journal-title":"J Neurotrauma"}],"container-title":["Journal of Head Trauma Rehabilitation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00001199-201203000-00006","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T19:02:56Z","timestamp":1786042976000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00001199-201203000-00006"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,3]]},"references-count":37,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2012]]}},"URL":"https:\/\/doi.org\/10.1097\/htr.0b013e31820e6840","relation":{},"ISSN":["0885-9701"],"issn-type":[{"value":"0885-9701","type":"print"}],"subject":[],"published":{"date-parts":[[2012,3]]}}}