{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T20:28:33Z","timestamp":1787257713347,"version":"build-2736575974"},"reference-count":25,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"9","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>While central serous chorioretinopathy is typically associated with pachychoroid, a subset of patients presents with thin choroids. This study aims to compare the clinical features of central serous chorioretinopathy in thin versus thick choroid eyes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      In this retrospective multicenter study, patients were categorized by subfoveal choroidal thickness into thin (\u2264250\n                      <jats:italic toggle=\"yes\">\u00b5<\/jats:italic>\n                      m) and thick (\u2265400\n                      <jats:italic toggle=\"yes\">\u00b5<\/jats:italic>\n                      m) groups. Multimodal imaging was used to analyze central macular thickness, subfoveal choroidal thickness, neurosensory detachment height, Haller vessel thickness, and inner choroidal thickness at baseline and final visit.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Among 355 eyes, 52 (14.6%) had thin and 303 (85.4%) had thick choroids. Patients with thin choroids were older (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001) and more often female (38.5% vs. 23.1%,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.019). Visual acuity was similar at baseline (0.30 log minimum angle of resolution [logMAR], Snellen equivalent [20\/40] versus 0.22 [20\/33], and\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.38) and final (0.18 logMAR, Snellen equivalent [20\/30] vs. 0.15 [20\/28], and\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.08) follow-up. Central macular thickness decreased in both groups, but subfoveal choroidal thickness, Haller vessel thickness, and inner choroidal thickness remained stable in the thin group. Spontaneous resolution and recurrence rates were similar; however, choroidal neovascularization development was significantly higher in the thin choroid group (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.003).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Thin-choroid central serous chorioretinopathy represents a distinct clinical phenotype with older age and female predominance. Although choroidal neovascularization occurred more frequently in this group compared with the thick choroid group, multivariate analysis indicates that age may be a key contributor to choroidal neovascularization risk.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1097\/iae.0000000000004875","type":"journal-article","created":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T17:00:29Z","timestamp":1778000429000},"page":"1570-1577","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["COMPARISON BETWEEN THIN AND THICK CHOROID EYES IN CENTRAL SEROUS CHORIORETINOPATHY"],"prefix":"10.1097","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1894-7772","authenticated-orcid":false,"given":"Sanya","family":"Yadav","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, West Virginia University; Morgantown, West Virginia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nasiq","family":"Hasan","sequence":"additional","affiliation":[{"name":"University of Pittsburgh School of Medicine; Pittsburgh, Pennsylvania, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niroj","family":"Sahoo","sequence":"additional","affiliation":[{"name":"Ophthalmology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arman","family":"Zarnegar","sequence":"additional","affiliation":[{"name":"University of Pittsburgh School of Medicine; Pittsburgh, Pennsylvania, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica","family":"Cao","sequence":"additional","affiliation":[{"name":"Retina Consultants of Texas, Houston, Texas;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Avery","family":"Zhou","sequence":"additional","affiliation":[{"name":"Retina Consultants of Texas, Houston, Texas;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stanley","family":"Saju","sequence":"additional","affiliation":[{"name":"Retina Consultants of Texas, Houston, Texas;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles C.","family":"Wykoff","sequence":"additional","affiliation":[{"name":"Retina Consultants of Texas, Houston, Texas;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priya","family":"Shah","sequence":"additional","affiliation":[{"name":"Harvard Medical School Department of Ophthalmology within Massachusetts Eye and Ear (MEE), Boston, Massachusetts;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Panisa","family":"Singhanetr","sequence":"additional","affiliation":[{"name":"Harvard Medical School Department of Ophthalmology within Massachusetts Eye and Ear (MEE), Boston, Massachusetts;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Rossin","sequence":"additional","affiliation":[{"name":"Harvard Medical School Department of Ophthalmology within Massachusetts Eye and Ear (MEE), Boston, Massachusetts;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorenzo Ferro","family":"Desideri","sequence":"additional","affiliation":[{"name":"Inselspital, University Hospital Bern, Bern, Switzerland;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felicia","family":"Hertkorn","sequence":"additional","affiliation":[{"name":"Gutblick, Pf\u00e4ffikon, Switzerland;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marion R.","family":"Munk","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Northwestern University Feinberg School of Medicine, Chicago, Illinois;"},{"name":"Inselspital, University Hospital Bern, Bern, Switzerland;"},{"name":"Gutblick, Pf\u00e4ffikon, Switzerland;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen","family":"Antia Rodriguez Fernandez","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Catalunya, Spain;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis A.","family":"Barquet","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Catalunya, Spain;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Institute of Vision Research, Gangnam Severance Hospital, Yonsei University College of Medicine, Gangnam-gu, Seoul, Republic of Korea;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stela","family":"Vujosevic","sequence":"additional","affiliation":[{"name":"Department of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy;"},{"name":"Eye Clinic, IRCCS MultiMedica, Milan, Italy;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuf","family":"Ashfaq","sequence":"additional","affiliation":[{"name":"Casey Eye Institute at Oregon Health and Science University, Portland, Oregon;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zachary","family":"Kroeger","sequence":"additional","affiliation":[{"name":"Department of Retina and Vitreous, L V Prasad Eye Institute, Vijayawada, India;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorenzo","family":"Pili","sequence":"additional","affiliation":[{"name":"Ophthalmology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Checchin","sequence":"additional","affiliation":[{"name":"Ophthalmology Unit, IRCCS San Raffaele Scientific Institute, Milan, 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