{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:14:37Z","timestamp":1786119277394,"version":"build-2736575974"},"reference-count":38,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2007,11]]},"DOI":"10.1097\/iae.0b013e3180592c00","type":"journal-article","created":{"date-parts":[[2009,3,4]],"date-time":"2009-03-04T21:44:36Z","timestamp":1236203076000},"page":"1279-1285","source":"Crossref","is-referenced-by-count":18,"title":["CORRELATION OF THE EXTENT AND DURATION OF RHEGMATOGENOUS RETINAL DETACHMENT WITH THE EXPRESSION OF MATRIX METALLOPROTEINASES IN THE VITREOUS"],"prefix":"10.1097","volume":"27","author":[{"given":"CHRYSANTHOS","family":"SYMEONIDIS","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"EUDOXIA","family":"DIZA","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ELENI","family":"PAPAKONSTANTINOU","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"EFIMIA","family":"SOULIOU","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"STAVROS A.","family":"DIMITRAKOS","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"GEORGE","family":"KARAKIULAKIS","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-21-20210130","first-page":"982","article-title":"Ophthalmology.","author":"Wilkinson","year":"2004"},{"key":"R2-21-20210130","first-page":"1002","article-title":"Ophthalmology.","author":"Aylward","year":"2004"},{"key":"R3-21-20210130","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1007\/s00417-006-0386-3","article-title":"Expression of matrix metalloproteinases in the subretinal fluid correlates with the extent of rhegmatogenous retinal detachment.","volume":"245","author":"Symeonidis","year":"2007","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"R4-21-20210130","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.survophthal.2003.10.003","article-title":"Subretinal fluid in primary rhegmatogenous retinal detachment: pathophysiology and composition.","volume":"49","author":"Quintyn","year":"2004","journal-title":"Surv Ophthalmol"},{"key":"R5-21-20210130","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1136\/bjo.84.6.654","article-title":"Matrix metalloproteinase biology applied to vitreoretinal disorders.","volume":"84","author":"Sethi","year":"2000","journal-title":"Br J Ophthalmol"},{"key":"R6-21-20210130","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S1350-9462(01)00015-5","article-title":"MMPs in the eye: emerging roles for matrix metallo-proteinases in ocular pathology.","volume":"21","author":"Sivak","year":"2002","journal-title":"Prog Retin Eye Res"},{"key":"R7-21-20210130","first-page":"853","article-title":"TGF- increases retinal endothelial cell permeability by increasing MMP-9: possible role of glial cells in endothelial cells in endothelial barrier function.","volume":"42","author":"Behzadian","year":"2001","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"R8-21-20210130","first-page":"2767","article-title":"Modulation of matrix metalloproteinase and TIMP-1 expression by cytokines in human RPE cells.","volume":"43","author":"Eichler","year":"2002","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"R9-21-20210130","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1161\/01.RES.0000070112.80711.3D","article-title":"Matrix metalloproteinases and tissue inhibitors of metalloproteinases-structure, function, and biochemistry.","volume":"92","author":"Visse","year":"2003","journal-title":"Circ Res"},{"key":"R10-21-20210130","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1146\/annurev.cb.09.110193.002545","article-title":"Tumor cell interactions with the extracellular matrix during invasion and metastasis.","volume":"9","author":"Stetler-Stevenson","year":"1993","journal-title":"Annu Rev Cell Biol"},{"key":"R11-21-20210130","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1074\/jbc.270.2.801","article-title":"The C-terminal region of membrane type matrix metalloproteinase is a functional trans-membrane domain required for pro-gelatinase A activation.","volume":"270","author":"Cao","year":"1995","journal-title":"J Biol Chem"},{"key":"R12-21-20210130","first-page":"509","article-title":"Human keratinocyte cell lines differ in the expression of the collagenolytic matrix metalloproteinases \u20131, \u20138 and \u201313 and of TIMP-1.","volume":"381","author":"Bachmeier","year":"2000","journal-title":"Biol Chem"},{"key":"R13-21-20210130","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1615\/CritRevEukarGeneExpr.v7.i1-2.90","article-title":"Transcriptional control of matrix metalloproteinases and the tissue inhibitors of matrix metalloproteinases.","volume":"7","author":"Borden","year":"1997","journal-title":"Crit Rev Euk Gene Exp"},{"key":"R14-21-20210130","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1016\/S0002-9394(98)00041-5","article-title":"Gelatinase B in proliferative vitreoretinal disorders.","volume":"125","author":"Abu El-Asrar","year":"1998","journal-title":"Am J Ophthalmol"},{"key":"R15-21-20210130","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1136\/bjo.84.10.1091","article-title":"Matrix metalloproteinases and their natural inhibitors in fibrovascular membranes of proliferative diabetic retinopathy.","volume":"84","author":"Salzmann","year":"2000","journal-title":"Br J Ophthalmol"},{"key":"R16-21-20210130","doi-asserted-by":"crossref","first-page":"1555","DOI":"10.1016\/S0002-9440(10)62540-0","article-title":"Matrix metalloproteinases: a role in the contraction of vitreo-retinal scar tissue.","volume":"159","author":"Sheridan","year":"2001","journal-title":"Am J Pathol"},{"key":"R17-21-20210130","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1006\/exer.1998.0585","article-title":"Predominance of MMP-1 and MMP-2 in epiretinal and subretinal membranes of proliferative vitreoretinopathy.","volume":"68","author":"Webster","year":"1999","journal-title":"Exp Eye Res"},{"key":"R18-21-20210130","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1006\/exer.2001.1112","article-title":"Drusen are cold spots for proteolysis: expression of matrix metalloproteinases and their tissue inhibitor proteins in age-related macular degeneration.","volume":"74","author":"Leu","year":"2002","journal-title":"Exp Eye Res"},{"key":"R19-21-20210130","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1146\/annurev.cellbio.17.1.463","article-title":"How matrix metalloproteinases regulate cell behavior.","volume":"17","author":"Sternlicht","year":"2001","journal-title":"Annu Rev Cell Dev Biol"},{"key":"R20-21-20210130","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1006\/exer.2001.1152","article-title":"Expression of matrix metalloproteinases and their inhibitors in experimental retinal ischemia-perfusion injury in rats.","volume":"74","author":"Zhang","year":"2002","journal-title":"Exp Eye Res"},{"key":"R21-21-20210130","first-page":"214","article-title":"Structural remodelling in heart failure: gelatinase induction.","volume":"10","author":"Armstrong","year":"1994","journal-title":"Can J Cardiol"},{"key":"R22-21-20210130","first-page":"145","article-title":"Regulation of metalloproteinase gene expression: implications for osteoarthritis.","volume":"2","author":"Brinckerhoff","year":"1992","journal-title":"Crit Rev Euk Gene Exp"},{"key":"R23-21-20210130","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1093\/jnci\/89.17.1260","article-title":"Changing views of the role of matrix metalloproteinases in metastasis.","volume":"89","author":"Chambers","year":"1997","journal-title":"J Natl Cancer Inst"},{"key":"R24-21-20210130","first-page":"2922","article-title":"Regulation of collagenase, stromelysin and gelatinase B in human conjunctival and conjunctivochalasis fibroblasts by interleukin-1beta and tumor necrosis factor-alpha.","volume":"41","author":"Meller","year":"2000","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"R25-21-20210130","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1016\/j.jaad.2004.01.055","article-title":"Expression of matrix metalloproteinases and their endogenous tissue inhibitors in skin lesions from patients with tuberous sclerosis.","volume":"51","author":"Papakonstantinou","year":"2004","journal-title":"J Am Acad Dermatol"},{"key":"R26-21-20210130","first-page":"121","article-title":"The classification of retinal detachment with proliferative vitreoretinopathy.","volume":"90","year":"1983","journal-title":"Am J Ophthalmol"},{"key":"R27-21-20210130","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1006\/exer.1998.0552","article-title":"Increase in interphotoreceptor matrix gelatinase A (MMP-2) associated with age-related macular degeneration.","volume":"67","author":"Plantner","year":"1998","journal-title":"Exp Eye Res"},{"key":"R28-21-20210130","first-page":"158","article-title":"Increased type IV collagen-degrading activity in metastases originating from primary tumors of the human colon.","volume":"17","author":"Karakiulakis","year":"1997","journal-title":"Invasion Metastasis"},{"key":"R29-21-20210130","doi-asserted-by":"crossref","first-page":"639","DOI":"10.3109\/02713689408999899","article-title":"Characterization of an endogenous metalloproteinase in human vitreous.","volume":"13","author":"Brown","year":"1994","journal-title":"Curr Eye Res"},{"key":"R30-21-20210130","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1076\/ceyr.17.2.132.5610","article-title":"Matrix metalloproteinases and metalloproteinase inhibitors in human interphotoreceptor matrix and vitreous.","volume":"17","author":"Plantner","year":"1998","journal-title":"Curr Eye Res"},{"key":"R31-21-20210130","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/S0021-5155(98)00038-0","article-title":"TIMP-1 and TIMP-2 levels in vitreous and subretinal fluid.","volume":"42","author":"Matsuo","year":"1998","journal-title":"Jpn J Ophthalmol"},{"key":"R32-21-20210130","first-page":"1524","article-title":"A prospective study of matrix metalloproteinases in proliferative vitreoretinopathy.","volume":"39","author":"Kon","year":"1998","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"R33-21-20210130","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/S1368-8375(99)00004-4","article-title":"Matrix metalloproteinases and oral cancer.","volume":"35","author":"Thomas","year":"1999","journal-title":"Oral Oncol"},{"key":"R34-21-20210130","first-page":"210","article-title":"The balance between proteinases and inhibitors in a murine model of proliferative retinopathy.","volume":"42","author":"Majka","year":"2001","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"R35-21-20210130","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1159\/000074567","article-title":"Role of retinal detachment subretinal fluid on extracellular matrix metabolism.","volume":"218","author":"Gonzalez-Avila","year":"2004","journal-title":"Ophthalmologica"},{"key":"R36-21-20210130","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1089\/1080768041223657","article-title":"Preventive versus treatment effect of AG3340, a potent matrix metalloproteinase inhibitor in a rat model of choroidal neovascularization.","volume":"20","author":"El Bradey","year":"2004","journal-title":"J Ocul Pharmacol Ther"},{"key":"R37-21-20210130","first-page":"S974","article-title":"The effect of AG3340 a potent inhibitor of matrix metalloproteinase on a subacute model of proliferative vitreoretinopathy.","volume":"40","author":"Ozerdem","year":"1999","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"R38-21-20210130","doi-asserted-by":"crossref","first-page":"425","DOI":"10.2174\/0929867013373417","article-title":"The design, structure and therapeutic application of matrix metalloproteinase inhibitors.","volume":"8","author":"Skiles","year":"2001","journal-title":"Curr Med Chem"}],"container-title":["Retina"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00006982-200711000-00021","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T17:48:50Z","timestamp":1786038530000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00006982-200711000-00021"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,11]]},"references-count":38,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2007]]}},"URL":"https:\/\/doi.org\/10.1097\/iae.0b013e3180592c00","relation":{},"ISSN":["0275-004X"],"issn-type":[{"value":"0275-004X","type":"print"}],"subject":[],"published":{"date-parts":[[2007,11]]}}}