{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:09:59Z","timestamp":1786118999473,"version":"build-2736575974"},"reference-count":21,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2008,6]]},"DOI":"10.1097\/iae.0b013e318177f934","type":"journal-article","created":{"date-parts":[[2008,5,27]],"date-time":"2008-05-27T03:06:41Z","timestamp":1211857601000},"page":"831-838","source":"Crossref","is-referenced-by-count":204,"title":["INTRAVITREAL INJECTION OF BEVACIZUMAB (AVASTIN) FOR TREATMENT OF STAGE 3 RETINOPATHY OF PREMATURITY IN ZONE I OR POSTERIOR ZONE II"],"prefix":"10.1097","volume":"28","author":[{"given":"HELEN A.","family":"MINTZ-HITTNER","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"RONALD R.","family":"KUFFEL","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-7-20210130","doi-asserted-by":"crossref","first-page":"4738","DOI":"10.1523\/JNEUROSCI.15-07-04738.1995","article-title":"Development of retinal vasculature is mediated by hypoxia-induced vascular endothelial growth factor (VEGF) expression by neuroglia.","volume":"15","author":"Stone","year":"1995","journal-title":"J Neurosci"},{"key":"R2-7-20210130","doi-asserted-by":"crossref","first-page":"1684","DOI":"10.1001\/archopht.121.12.1684","article-title":"Revised indications for the treatment of retinopathy of prematurity: results of the Early Treatment for Retinopathy of Prematurity Randomized Trial.","volume":"121","year":"2003","journal-title":"Arch Ophthalmol"},{"key":"R3-7-20210130","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1542\/peds.2005-2749","article-title":"Screening examination of premature infants for retinopathy of prematurity.","volume":"117","year":"2006","journal-title":"Pediatrics"},{"key":"R4-7-20210130","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1001\/archopht.125.7.875","article-title":"Interexpert agreement of plus disease diagnosis in retinopathy of prematurity.","volume":"125","author":"Chiang","year":"2007","journal-title":"Arch Ophthalmol"},{"key":"R5-7-20210130","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1001\/archopht.123.3.406-a","article-title":"The evidence supporting the early treatment for type 1 retinopathy of prematurity needs further evaluation.","volume":"123","author":"Averbukh","year":"2005","journal-title":"Arch Ophthalmol"},{"key":"R6-7-20210130","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1001\/archopht.123.3.408","article-title":"The dilemma of exercising clinical judgment in the treatment of retinopathy of prematurity.","volume":"123","author":"Coats","year":"2005","journal-title":"Arch Ophthalmol"},{"key":"R7-7-20210130","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1001\/archopht.123.3.407","article-title":"Clinical application of the revised indications for the treatment of retinopathy of prematurity.","volume":"123","author":"Jalali","year":"2005","journal-title":"Arch Ophthalmol"},{"key":"R8-7-20210130","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1001\/archopht.123.3.406-b","article-title":"Revised indications for early treatment of retinopathy of prematurity.","volume":"123","author":"Vander","year":"2005","journal-title":"Arch Ophthalmol"},{"key":"R9-7-20210130","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1136\/bjo.84.12.1383","article-title":"Diode laser treatment of posterior retinopathy of prematurity.","volume":"84","author":"Axer-Siegel","year":"2000","journal-title":"Br J Ophthalmol"},{"key":"R10-7-20210130","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1111\/j.1395-3907.2003.00171.x","article-title":"Outcome of zone I retinopathy of prematurity.","volume":"81","author":"O\u2019Keefe","year":"2003","journal-title":"Acta Ophthalmol Scand"},{"key":"R11-7-20210130","doi-asserted-by":"crossref","first-page":"204","DOI":"10.3928\/0191-3913-20030701-06","article-title":"Laser treatment of zone I prethreshold and stage 3 threshold retinopathy of prematurity.","volume":"40","author":"R\u00e9cs\u00e1n","year":"2003","journal-title":"J Pediatr Ophthalmol Strabismus"},{"key":"R12-7-20210130","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1067\/mpa.2000.107904","article-title":"Zone I retinopathy of prematurity.","volume":"4","author":"Katz","year":"2004","journal-title":"J Am Assoc Pediatr Ophthalmol Strabismus"},{"key":"R13-7-20210130","doi-asserted-by":"crossref","first-page":"S11","DOI":"10.1097\/01.iae.0000244285.79004.e6","article-title":"Zone I retinopathy of prematurity: clinical characteristics and treatment outcomes.","volume":"26","author":"Kychenthal","year":"2006","journal-title":"Retina"},{"key":"R14-7-20210130","first-page":"493","article-title":"Long-term visual outcomes in extremely low-birth-weight children (an American Ophthalmological Society Thesis).","volume":"104","author":"Spencer","year":"2006","journal-title":"Trans Am Ophthalmol Soc"},{"key":"R15-7-20210130","doi-asserted-by":"crossref","first-page":"1727","DOI":"10.1007\/s00417-007-0661-y","article-title":"Combination of laser photocoagulation and intravitreal bevacizumab (Avastin\u00ae) for aggressive zone I retinopathy of prematurity.","volume":"245","author":"Chung","year":"2007","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"R16-7-20210130","doi-asserted-by":"crossref","first-page":"233","DOI":"10.3928\/15428877-20070501-09","article-title":"Intravitreal bevacizumab in aggressive posterior retinopathy of prematurity.","volume":"38","author":"Travassos","year":"2007","journal-title":"Ophthalmic Surg Lasers Imaging"},{"key":"R17-7-20210130","doi-asserted-by":"crossref","first-page":"75","DOI":"10.4103\/0301-4738.29505","article-title":"Intravitreal bevacizumab (Avastin) for post laser anterior segment ischemia in aggressive posterior retinopathy of prematurity.","volume":"55","author":"Shah","year":"2007","journal-title":"Indian J Ophthalmol"},{"key":"R18-7-20210130","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1001\/archopht.123.7.991","article-title":"The International Classification of Retinopathy of Prematurity revisited.","volume":"123","year":"2005","journal-title":"Arch Ophthalmol"},{"key":"R19-7-20210130","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1001\/archopht.1988.01060130517027","article-title":"Multicenter trial of cryotherapy for retinopathy of prematurity: preliminary results.","volume":"106","year":"1988","journal-title":"Arch Ophthalmol"},{"key":"R20-7-20210130","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1016\/S0161-6420(94)31301-7","article-title":"Postnatal retinal vascularization in former preterm infants with retinopathy of prematurity.","volume":"101","author":"Mintz-Hittner","year":"1994","journal-title":"Ophthalmology"},{"key":"R21-7-20210130","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1016\/j.ophtha.2007.01.017","article-title":"Pharmacokinetics of intravitreal bevacizumab (Avastin).","volume":"114","author":"Bakri","year":"2007","journal-title":"Ophthalmology"}],"container-title":["Retina"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00006982-200806000-00007","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T17:10:17Z","timestamp":1786036217000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00006982-200806000-00007"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,6]]},"references-count":21,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2008]]}},"URL":"https:\/\/doi.org\/10.1097\/iae.0b013e318177f934","relation":{},"ISSN":["0275-004X"],"issn-type":[{"value":"0275-004X","type":"print"}],"subject":[],"published":{"date-parts":[[2008,6]]}}}