{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T14:36:32Z","timestamp":1784298992985,"version":"3.55.0"},"reference-count":13,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017]]},"abstract":"<jats:sec>\n            <jats:title>Purpose:<\/jats:title>\n            <jats:p>To report the case of a 44-year-old woman with acute transient visual loss likely because of idiopathic pulmonary arterial hypertension.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods:<\/jats:title>\n            <jats:p>Case report imaged with fundus photographs, spectral-domain optical coherence tomography, fundus autofluorescence, and fluorescein and indocyanine green angiographies.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results:<\/jats:title>\n            <jats:p>The patient complained of unilateral vision loss with metamorphopsia. Fundus examination of the right eye showed serous macular detachment and retinal folds. Fluorescein angiography and indocyanine green angiography showed delayed choroidal filling with multiple choroidal perfusion defects and dye leakage from areas of multiple pigment epithelial detachments. Spectral-domain optical coherence tomography showed a thick choroid. Medical history included idiopathic pulmonary arterial hypertension treated with tadalafil. Ocular signs regressed spontaneously within 1 week.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion:<\/jats:title>\n            <jats:p>Transient severe choroidal filling defects with subretinal exudation may be observed in idiopathic pulmonary arterial hypertension. The present case raised the questions of the triggering factor of the acute decompensation of the blood\u2013retinal barrier and the cause of its spontaneous regression.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/icb.0000000000000336","type":"journal-article","created":{"date-parts":[[2016,5,20]],"date-time":"2016-05-20T14:22:51Z","timestamp":1463754171000},"page":"261-265","source":"Crossref","is-referenced-by-count":15,"title":["ACUTE SEROUS RETINAL DETACHMENT IN IDIOPATHIC PULMONARY ARTERIAL HYPERTENSION"],"prefix":"10.1097","volume":"11","author":[{"given":"David","family":"Martiano","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Centre Hospitalier Intercommunal de Cr\u00e9teil, Universit\u00e9 Paris Est, Paris, France; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Chevreaud","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Centre Hospitalier Intercommunal de Cr\u00e9teil, Universit\u00e9 Paris Est, Paris, France; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Delphine","family":"Lam","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Centre Hospitalier Intercommunal de Cr\u00e9teil, Universit\u00e9 Paris Est, Paris, France; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salomon Y.","family":"Cohen","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Centre Hospitalier Intercommunal de Cr\u00e9teil, Universit\u00e9 Paris Est, Paris, France; and"},{"name":"The Centre Ophtalmologique d'Imagerie et de Laser, Paris, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric H.","family":"Souied","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Centre Hospitalier Intercommunal de Cr\u00e9teil, Universit\u00e9 Paris Est, Paris, France; and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20230817","doi-asserted-by":"crossref","first-page":"1976","DOI":"10.1016\/j.jacc.2015.03.540","article-title":"Management of pulmonary arterial hypertension","volume":"65","author":"McLaughlin","year":"2015","journal-title":"J Am Coll Cardiol"},{"key":"R2-20230817","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1136\/jmg.37.10.741","article-title":"Sporadic primary pulmonary hypertension is associated with germline mutations of the gene encoding BMPR-II, a receptor member of the TGF-\u03b2 family","volume":"37","author":"Thomson","year":"2000","journal-title":"J Med Genet"},{"key":"R3-20230817","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1097\/ICB.0b013e31828eefce","article-title":"Flecked retina, choroidopathy, and retinal pigment epithelial tear in familial pulmonary arterial hypertension","volume":"7","author":"Torfs","year":"2013","journal-title":"Retin Cases Brief Rep"},{"key":"R4-20230817","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1097\/ICB.0000000000000090","article-title":"Multifocal central serous chorioretinopathy with photoreceptor-retinal pigment epithelium diastasis in heritable pulmonary arterial hypertension","volume":"9","author":"Li","year":"2015","journal-title":"Retin Cases Brief Rep"},{"key":"R5-20230817","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1007\/s00417-004-1099-0","article-title":"Viagra-associated serous macular detachment","volume":"243","author":"Quiram","year":"2005","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"R6-20230817","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1097\/WNO.0b013e318167554a","article-title":"Bilateral posterior ischemic optic neuropathy associated with use of sildenafil","volume":"28","author":"Su","year":"2008","journal-title":"J Neuroophthalmol"},{"key":"R7-20230817","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.1136\/bjo.2008.149013","article-title":"Non-arteritic anterior ischaemic optic neuropathy and phosphodiesterase-5 inhibitors","volume":"92","author":"Hayreh","year":"2008","journal-title":"Br J Ophthalmol"},{"key":"R8-20230817","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2165\/00002018-200932010-00001","article-title":"Vision disorders and phosphodiesterase type 5 inhibitors","volume":"32","author":"Laties","year":"2009","journal-title":"Drug Saf"},{"key":"R9-20230817","doi-asserted-by":"crossref","first-page":"2894","DOI":"10.1111\/j.1743-6109.2011.02382.x","article-title":"Are phosphodiesterase type 5 inhibitors associated with vision-threatening adverse events? 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