{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T03:22:45Z","timestamp":1775704965424,"version":"3.50.1"},"reference-count":18,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:sec>\n            <jats:title>Purpose:<\/jats:title>\n            <jats:p>We report a patient with <jats:italic toggle=\"yes\">CTNNB1<\/jats:italic>-associated vitreoretinopathy. We discuss imaging findings and surgical management.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods:<\/jats:title>\n            <jats:p>Case report.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results:<\/jats:title>\n            <jats:p>An 18-month-old girl with microcephaly, failure to thrive, developmental delay, and chronic rhinitis presented with bilateral central and peripheral tractional retinal detachments and an anomalous retinal vasculature. She underwent multimodal imaging and genetic testing, and we discuss successful surgical management.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion:<\/jats:title>\n            <jats:p>\n                                 <jats:italic toggle=\"yes\">CTNNB1<\/jats:italic> mutations can cause a vision-threatening vitreoretinopathy. We recommend <jats:italic toggle=\"yes\">CTNNB1<\/jats:italic> to be considered as part of the workup of patients presenting with familial exudative vitreoretinopathy\u2013like clinical findings, especially if there are systemic manifestations.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/icb.0000000000000990","type":"journal-article","created":{"date-parts":[[2020,3,9]],"date-time":"2020-03-09T08:04:09Z","timestamp":1583741049000},"page":"259-262","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":4,"title":["CTNNB1 (\u03b2-CATENIN) VITREORETINOPATHY: IMAGING CHARACTERISTICS AND SURGICAL MANAGEMENT"],"prefix":"10.1097","volume":"16","author":[{"given":"Boontip","family":"Tipsuriyaporn","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael J.","family":"Ammar","sequence":"additional","affiliation":[{"name":"Wills Eye Hospital Retina Service, Mid Atlantic Retina, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshihiro","family":"Yonekawa","sequence":"additional","affiliation":[{"name":"Wills Eye Hospital Retina Service, Mid Atlantic Retina, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","published-online":{"date-parts":[[2020,3,5]]},"reference":[{"key":"R1-20250507","doi-asserted-by":"crossref","first-page":"3337","DOI":"10.1242\/jcs.013771","article-title":"Mechanistic insights from structural studies of beta-catenin and its binding partners","volume":"120","author":"Xu","year":"2007","journal-title":"J Cell 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