{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T13:20:22Z","timestamp":1787750422061,"version":"build-2784847793"},"reference-count":0,"publisher":"Ovid Technologies (Wolters Kluwer Health)","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,6,25]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>\n                      To report a case of unilateral endogenous\n                      <jats:italic toggle=\"yes\">Streptococcus anginosus<\/jats:italic>\n                      endophthalmitis in order to improve timely recognition and treatment strategies for similar presentations.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A retrospective review of the electronic medical record of one patient was performed from September 2024 through December 2024.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      A 50-year-old healthy male presented with a unilateral hypopyon and dense vitreous opacities. The patient was found to have evidence of systemic infection and endophthalmitis secondary to\n                      <jats:italic toggle=\"yes\">S. anginosus;<\/jats:italic>\n                      specifically, the patient was found to have a large subcarinal mass as well as abscesses in the left cerebrum, both of which were positive for\n                      <jats:italic toggle=\"yes\">S. anginosus<\/jats:italic>\n                      . The patient underwent treatment with intravitreal and systemic antibiotics as well as pars plana vitrectomy.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>\n                      <jats:italic toggle=\"yes\">S. anginosus<\/jats:italic>\n                      endophthalmitis in the setting of a confirmed primary mediastinal infection has not previously been reported. Our patient had a particularly virulent presentation of\n                      <jats:italic toggle=\"yes\">S. anginosus<\/jats:italic>\n                      endophthalmitis, and the ophthalmic findings led to the diagnosis of a systemic infection. A thorough systemic evaluation of patients with suspected endogenous endophthalmitis should be pursued, and a seemingly noncontributory medical history can prove to be significant.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1097\/icb.0000000000001908","type":"journal-article","created":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T16:05:36Z","timestamp":1782403536000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Endogenous Streptococcus Anginosus Endophthalmitis: A Case Report and Review of the Literature"],"prefix":"10.1097","author":[{"given":"Nish","family":"Patel","sequence":"first","affiliation":[{"name":"Kellogg Eye Center, Michigan Medicine, Ann Arbor, MI, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tejaswini","family":"Matsyaraja","sequence":"additional","affiliation":[{"name":"Kellogg Eye Center, Michigan Medicine, Ann Arbor, MI, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marten R.","family":"Hawkins","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, University of Michigan Medical School, Ann Arbor, MI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shilpa","family":"Kodati","sequence":"additional","affiliation":[{"name":"Kellogg Eye Center, Michigan Medicine, Ann Arbor, MI, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","container-title":["RETINAL Cases &amp; Brief Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.1097\/ICB.0000000000001908","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T12:33:28Z","timestamp":1787747608000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.1097\/ICB.0000000000001908"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,25]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1097\/icb.0000000000001908","relation":{},"ISSN":["1935-1089"],"issn-type":[{"value":"1935-1089","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6,25]]}}}